Infective endocarditis

Common Name(s)

Infective endocarditis

Infective endocarditis is an infection of the heart lining, heart valves, or blood vessels. The infection is usually caused by bacteria (bacterial endocarditis) but in some rare cases can be caused by fungus (fungal endocarditis). The risk of endocarditis is greater in individuals with heart conditions that prevent blood from moving correctly through the heart, such as those with congenital heart defects, damaged heart valves, or an implanted heart device. Those who have HIV/AIDS or IV drug users are also at increased risk for developing infective endocarditis.

Symptoms of infective endocarditis include fever, chills, fatigue, and achiness. Later symptoms include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. The symptoms of infective endocarditis will typically become more severe over time as the bacteria or fungi continues to grow. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Infective endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment usually includes IV antibiotics. Good dental hygiene is an important preventative measure, as bacteria from the mouth are likely to enter the bloodstream and can then grow in the heart. Check with your doctor if you think you may be at risk for endocarditis, and you may be given antibiotics to take before a dental procedure. If you have been diagnosed with infective endocarditis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Infective endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infective endocarditis" returned 893 free, full-text research articles on human participants. First 3 results:

[Infective endocarditis in patients with ventricular septal defect: the role of echocardiography and prophylactic antibiotic therapy].
 

Author(s): Hanane Boussir, Amine Ghalem, Nabila Ismaili, Noha El Ouafi

Journal:

 

Infective endocarditis can occur in healthy people or in those with a preexisting heart disease. Among people with heart disease at risk for developing infective endocarditis, there are those with congenital heart disease (VSD is the most common type). We report the case of a 17-year ...

Last Updated: 15 Mar 2017

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[Sylvian and mesenteric arteries aneurysm revealing infective endocarditis].
 

Author(s): Amine Ghalem, Houssam Laachach, Alaa Fliti, Abdelmalek Elyandouzi, Abdelwahab Elkasimi, Nabila Ismaili, Noha El Ouafi

Journal:

 

Infective endocarditis is an emergency condition usually diagnosed in the context of an infectious syndrome associated with heart murmur. It can lead to life-threatening complications. We report the case of a patient with endocarditis presenting as neuro-abdominal manifestations associated ...

Last Updated: 15 Mar 2017

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[Broad ischemic stroke revealing infective endocarditis in a young patient: about a case].
 

Author(s): Fanomezantsoa Noella Ravelosaona, Julien Razafimahefa, Rahamefy Odilon Randrianasolo, Solofonirina Rakotoarimanana, Djacoba Alain Tehindrazanarivelo

Journal:

 

Broad ischemic stroke is mainly due to a cardiac embolus or to an atheromatous plaque. In young subjects, one of the main causes of ischemic stroke (broad ischemic stroke in particolar) is embolic heart disease including infective endocarditis. Infective endocarditis is a contraindication ...

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infective endocarditis" returned 100 free, full-text review articles on human participants. First 3 results:

Could Early Surgery Get Beneficial in Adult Patients with Active Native Infective Endocarditis? A Meta-Analysis.
 

Author(s): Liqun Jia, Zanxin Wang, Qiang Fu, Huaien Bu, Minxin Wei

Journal: Biomed Res Int. 2017 ;2017():3459468.

 

After a thorough search through the database as PubMed database and Embase database, the clinical experimental articles have been selected out on the effects of early surgery on the treatment of active native infective endocarditis. The quality of the trials included in this study ...

Last Updated: 22 Mar 2017

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Managing infective endocarditis in the elderly: new issues for an old disease.
 

Author(s): Emmanuel Forestier, Thibaut Fraisse, Claire Roubaud-Baudron, Christine Selton-Suty, Leonardo Pagani

Journal:

 

The incidence of infective endocarditis (IE) rises in industrialized countries. Older people are more affected by this severe disease, notably because of the increasing number of invasive procedures and intracardiac devices implanted in these patients. Peculiar clinical and echocardiographic ...

Last Updated: 13 Sep 2016

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Development and evaluation of a novel fast broad-range 16S ribosomal DNA PCR and sequencing assay for diagnosis of bacterial infective endocarditis: multi-year experience in a large Canadian healthcare zone and a literature review.
 

Author(s): Robert J H Miller, Barbara Chow, Dylan Pillai, Deirdre Church

Journal:

 

The study aimed to explore the sensitivity and specificity of a novel fast 16S rDNA PCR and sequencing assay for the improved diagnosis of infective endocarditis (IE) in patients with suspected native or prosthetic heart valve (HV) infection over a multi-year period at our cardiovascular center.

Last Updated: 12 Apr 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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Last Updated: 19 Oct 2016

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Infective Endocarditis in the Elderly
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 21 Sep 2016

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