Infective endocarditis

Common Name(s)

Infective endocarditis

Infective endocarditis is an infection of the heart lining, heart valves, or blood vessels. The infection is usually caused by bacteria (bacterial endocarditis) but in some rare cases can be caused by fungus (fungal endocarditis). The risk of endocarditis is greater in individuals with heart conditions that prevent blood from moving correctly through the heart, such as those with congenital heart defects, damaged heart valves, or an implanted heart device. Those who have HIV/AIDS or IV drug users are also at increased risk for developing infective endocarditis.

Symptoms of infective endocarditis include fever, chills, fatigue, and achiness. Later symptoms include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. The symptoms of infective endocarditis will typically become more severe over time as the bacteria or fungi continues to grow. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Infective endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment usually includes IV antibiotics. Good dental hygiene is an important preventative measure, as bacteria from the mouth are likely to enter the bloodstream and can then grow in the heart. Check with your doctor if you think you may be at risk for endocarditis, and you may be given antibiotics to take before a dental procedure. If you have been diagnosed with infective endocarditis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Infective endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infective endocarditis" returned 938 free, full-text research articles on human participants. First 3 results:

Infective endocarditis in patients with cancer: a consequence of invasive procedures or a harbinger of neoplasm?: A prospective, multicenter cohort.
 

Author(s): Ana Fernández-Cruz, Patricia Muñoz, Carmen Sandoval, Carmen Fariñas, Manuel Gutiérrez-Cuadra, Juan M Pericás Pulido, José M Miró, Miguel Á Goenaga-Sánchez, Arístides de Alarcón, Francisco Bonache-Bernal, MªÁngeles Rodríguez, Mariam Noureddine, Emilio Bouza Santiago,

Journal: Medicine (Baltimore). 2017 Sep;96(38):e7913.

 

The aim of the study was to draw a comparison between the characteristics of infective endocarditis (IE) in patients with cancer and those of IE in noncancer patients.Patients with IE, according to the modified Duke criteria, were prospectively included in the GAMES registry between ...

Last Updated: 31 Dec 1969

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First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report.
 

Author(s): Iva Kotaskova, Petr Nemec, Martina Vanerkova, Barbora Malisova, Renata Tejkalova, Marek Orban, Vita Zampachova, Tomas Freiberger

Journal:

 

The presence of more than one bacterial agent is relatively rare in infective endocarditis, although more common in prosthetic cases. Molecular diagnosis from a removed heart tissue is considered a quick and effective way to diagnose fastidious or intracellular agents.

Last Updated: 31 Dec 1969

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Influence of Staphylococcus aureus on Outcomes after Valvular Surgery for Infective Endocarditis.
 

Author(s): Sang Myung Han, Robert A Sorabella, Sowmya Vasan, Mark Grbic, Daniel Lambert, Rahul Prasad, Catherine Wang, Paul Kurlansky, Michael A Borger, Rachel Gordon, Isaac George

Journal:

 

As Staphylococcus aureus (SA) remains one of the leading cause of infective endocarditis (IE), this study evaluates whether S. aureus is associated with more severe infections or worsened outcomes compared to non-S. aureus (NSA) organisms.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infective endocarditis" returned 108 free, full-text review articles on human participants. First 3 results:

The prognosis of infective endocarditis treated with biological valves versus mechanical valves: A meta-analysis.
 

Author(s): Ende Tao, Li Wan, WenJun Wang, YunLong Luo, JinFu Zeng, Xia Wu

Journal:

 

Surgery remains the primary form of treatment for infective endocarditis (IE). However, it is not clear what type of prosthetic valve provides a better prognosis. We conducted a meta-analysis to compare the prognosis of infective endocarditis treated with biological valves to cases ...

Last Updated: 31 Dec 1969

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Bacteremia caused by Bergeyella zoohelcum in an infective endocarditis patient: case report and review of literature.
 

Author(s): Yili Chen, Kang Liao, Lu Ai, Penghao Guo, Han Huang, Zhongwen Wu, Min Liu

Journal:

 

Bergeyella zoohelcum is an aerobic, Gram-negative bacterium that is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B. zoohelcum has been reported causing cellulitis, tenosynovitis, leg abscess and septicemia, which is closely connected ...

Last Updated: 31 Dec 1969

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Could Early Surgery Get Beneficial in Adult Patients with Active Native Infective Endocarditis? A Meta-Analysis.
 

Author(s): Liqun Jia, Zanxin Wang, Qiang Fu, Huaien Bu, Minxin Wei

Journal: Biomed Res Int. 2017 ;2017():3459468.

 

After a thorough search through the database as PubMed database and Embase database, the clinical experimental articles have been selected out on the effects of early surgery on the treatment of active native infective endocarditis. The quality of the trials included in this study ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Metagenomics of Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 22 Jun 2017

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Infective Endocarditis in the Elderly
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 21 Sep 2016

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French National Observatory on Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 6 Sep 2017

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