Infective endocarditis

Common Name(s)

Infective endocarditis

Infective endocarditis is an infection of the heart lining, heart valves, or blood vessels. The infection is usually caused by bacteria (bacterial endocarditis) but in some rare cases can be caused by fungus (fungal endocarditis). The risk of endocarditis is greater in individuals with heart conditions that prevent blood from moving correctly through the heart, such as those with congenital heart defects, damaged heart valves, or an implanted heart device. Those who have HIV/AIDS or IV drug users are also at increased risk for developing infective endocarditis.

Symptoms of infective endocarditis include fever, chills, fatigue, and achiness. Later symptoms include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. The symptoms of infective endocarditis will typically become more severe over time as the bacteria or fungi continues to grow. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Infective endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment usually includes IV antibiotics. Good dental hygiene is an important preventative measure, as bacteria from the mouth are likely to enter the bloodstream and can then grow in the heart. Check with your doctor if you think you may be at risk for endocarditis, and you may be given antibiotics to take before a dental procedure. If you have been diagnosed with infective endocarditis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Infective endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infective endocarditis" returned 961 free, full-text research articles on human participants. First 3 results:

[Antibiotic prophylaxis against infective endocarditis].
 

Author(s): Lise Lund Håheim

Journal:

 

Last Updated: 24 Feb 2016

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Antineutrophil Cytoplasmic Antibodies Associated With Infective Endocarditis.
 

Author(s): Vincent Langlois, Anais Lesourd, Nicolas Girszyn, Jean-Francois Ménard, Hervé Levesque, Francois Caron, Isabelle Marie

Journal: Medicine (Baltimore). 2016 Jan;95(3):e2564.

 

To determine the prevalence of antineutrophil cytoplasmic antibodies (ANCA) in patients with infective endocarditis (IE) in internal medicine; and to compare clinical and biochemical features and outcome between patients exhibiting IE with and without ANCA.Fifty consecutive patients ...

Last Updated: 28 Jan 2016

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Systematic Search for Present and Potential Portals of Entry for Infective Endocarditis.
 

Author(s): François Delahaye, Ali M'Hammedi, Brice Guerpillon, Guy de Gevigney, André Boibieux, Olivier Dauwalder, Coralie Bouchiat, François Vandenesch

Journal: J. Am. Coll. Cardiol.. 2016 Jan;67(2):151-8.

 

Looking for and treating the portal of entry (POE) of infective endocarditis (IE) is important, but published research on this topic is nonexistent.

Last Updated: 21 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infective endocarditis" returned 102 free, full-text review articles on human participants. First 3 results:

Non-infective endocarditis with systemic embolization and recurrent stroke in systemic sclerosis.
 

Author(s): Ellen De Langhe, Alexandra Seghers, Philippe Demaerel, Patrick Verschueren, Robin Lemmens

Journal: Rheumatology (Oxford). 2016 Mar;55(3):589-91.

 

Last Updated: 10 Feb 2016

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The Preoperative Evaluation of Infective Endocarditis via 3-Dimensional Transesophageal Echocardiography.
 

Author(s): Matthew S Yong, Pankaj Saxena, Ammar M Killu, Sean Coffey, Harold M Burkhart, Siu-Hin Wan, Joseph F Malouf

Journal:

 

Transesophageal echocardiography continues to have a central role in the diagnosis of infective endocarditis and its sequelae. Recent technological advances offer the option of 3-dimensional imaging in the evaluation of patients with infective endocarditis. We present an illustrative ...

Last Updated: 28 Sep 2015

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Infective endocarditis involving an apparently structurally normal valve: new epidemiological trend?
 

Author(s): Jae-Kwan Song

Journal: Korean J. Intern. Med.. 2015 Jul;30(4):434-42.

 

Infective endocarditis (IE) has been increasingly diagnosed in patients without previously detected predisposing heart disease, but its clinical features have yet to be fully determined. A recent single-center study including echocardiographic images and surgical findings investigated ...

Last Updated: 16 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
 

Status: Not yet recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 30 Apr 2014

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Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 21 Feb 2013

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