Infective endocarditis

Common Name(s)

Infective endocarditis

Infective endocarditis is an infection of the heart lining, heart valves, or blood vessels. The infection is usually caused by bacteria (bacterial endocarditis) but in some rare cases can be caused by fungus (fungal endocarditis). The risk of endocarditis is greater in individuals with heart conditions that prevent blood from moving correctly through the heart, such as those with congenital heart defects, damaged heart valves, or an implanted heart device. Those who have HIV/AIDS or IV drug users are also at increased risk for developing infective endocarditis.

Symptoms of infective endocarditis include fever, chills, fatigue, and achiness. Later symptoms include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. The symptoms of infective endocarditis will typically become more severe over time as the bacteria or fungi continues to grow. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Infective endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment usually includes IV antibiotics. Good dental hygiene is an important preventative measure, as bacteria from the mouth are likely to enter the bloodstream and can then grow in the heart. Check with your doctor if you think you may be at risk for endocarditis, and you may be given antibiotics to take before a dental procedure. If you have been diagnosed with infective endocarditis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Infective endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infective endocarditis" returned 876 free, full-text research articles on human participants. First 3 results:

Bartonella henselae Infective Endocarditis Detected by a Prolonged Blood Culture.
 

Author(s): Tsutomu Mito, Yusuke Hirota, Shingo Suzuki, Kazutaka Noda, Takanori Uehara, Yoshiyuki Ohira, Masatomi Ikusaka

Journal: Intern. Med.. ;55(20):3065-3067.

 

A 65-year-old Japanese man was admitted with a 4-month history of fatigue and exertional dyspnea. Transthoracic echocardiography revealed a vegetation on the aortic valve and severe aortic regurgitation. Accordingly, infective endocarditis and heart failure were diagnosed. Although ...

Last Updated: 17 Oct 2016

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Enormous Pedunculated Vegetation Originating in the Left Ventricular Apex in a Patient with Infective Endocarditis.
 

Author(s): Azusa Murata, Kenji Inoue, Sonomi Maruyama, Shigekazu Iguchi, Manabu Sugita, Makoto Hiki, Shinya Okazaki, Iwao Okai, Yasumasa Fujiwara, Masataka Sumiyoshi, Taira Yamamoto, Atsushi Amano, Masao Daimon, Hiroyuki Daida

Journal: Intern. Med.. ;55(20):2971-2973.

 

A healthy teenage Japanese girl was admitted to our hospital after experiencing out-of-hospital cardiac arrest. She had attempted to commit suicide by taking 4,950 mg of disopyramide and 12 mg of flunitrazepam. Mechanical cardiopulmonary support was started with percutaneous cannulation ...

Last Updated: 17 Oct 2016

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Infective Endocarditis with Intermittent Atrioventricular Block and Pseudoaneurysm of the Mitral-aortic Intervalvular Fibrosa in a Patient with Severe Aortic Stenosis.
 

Author(s): Hideyuki Hasebe, Akira Takanohashi, Kazuaki Shirota, Hajime Nakamura

Journal: Intern. Med.. ;55(19):2825-2829.

 

Atrioventricular (AV) block and pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) are rare complications of infective endocarditis (IE). A 72-year-old man with severe aortic stenosis was hospitalized due to IE. After admission, intermittent AV block and P-MAIVF were ...

Last Updated: 11 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infective endocarditis" returned 96 free, full-text review articles on human participants. First 3 results:

Managing infective endocarditis in the elderly: new issues for an old disease.
 

Author(s): Emmanuel Forestier, Thibaut Fraisse, Claire Roubaud-Baudron, Christine Selton-Suty, Leonardo Pagani

Journal:

 

The incidence of infective endocarditis (IE) rises in industrialized countries. Older people are more affected by this severe disease, notably because of the increasing number of invasive procedures and intracardiac devices implanted in these patients. Peculiar clinical and echocardiographic ...

Last Updated: 13 Sep 2016

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Development and evaluation of a novel fast broad-range 16S ribosomal DNA PCR and sequencing assay for diagnosis of bacterial infective endocarditis: multi-year experience in a large Canadian healthcare zone and a literature review.
 

Author(s): Robert J H Miller, Barbara Chow, Dylan Pillai, Deirdre Church

Journal:

 

The study aimed to explore the sensitivity and specificity of a novel fast 16S rDNA PCR and sequencing assay for the improved diagnosis of infective endocarditis (IE) in patients with suspected native or prosthetic heart valve (HV) infection over a multi-year period at our cardiovascular center.

Last Updated: 12 Apr 2016

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Value of brain MRI in infective endocarditis: a narrative literature review.
 

Author(s): J Champey, P Pavese, H Bouvaist, A Kastler, A Krainik, P Francois

Journal: Eur. J. Clin. Microbiol. Infect. Dis.. 2016 Feb;35(2):159-68.

 

The nervous system is frequently involved in patients with infective endocarditis (IE). A systematic review of the literature was realized in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). This study sought to systematically evaluate ...

Last Updated: 25 Jan 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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Last Updated: 19 Oct 2016

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Infective Endocarditis in the Elderly
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 21 Sep 2016

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