Amyloidosis AA

Common Name(s)

Amyloidosis AA

Amyloidosis is a group of diseases in which a protein, called amyloid, builds up in the body's organs and tissues. Amyloidosis AA is also referred to as Secondary amyloidosis or Inflammatory amyloidosis. This disease is caused by a long-lasting infection or inflammatory disease such as rheumatoid arthritis, familial Mediterranean fever, or osteomyelitis. Infection or inflammation in the body causes an increased amount of a specific protein called serum amyloid A (SAA) protein. In this disease, part of the SAA protein forms deposits called "amyloid fibrils". These desposits occur in the space around the cells of certain tissues of the body. Amyloidosis AA usually begins as a disease in the kidneys, but other organs can be affected such as the liver and spleen. Medical or surgical treatment of the underlying infection or inflammatory disease can slow down or stop the progression of this condition.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Amyloidosis AA" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Amyloidosis AA" returned 83 free, full-text research articles on human participants. First 3 results:

Pearls from the Third Israeli Conference on FMF, other autoinflammatory disorders and AA amyloidosis.
 

Author(s): Avi Livneh, Ilan Ben-Zvi

Journal: Isr. Med. Assoc. J.. 2014 May;16(5):269-70.

 

Last Updated: 1 Jul 2014

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[Non AA amyloidosis and sarcoidosis revealed by an aggressive angiomyxoma of the pelvis. Rare association].
 

Author(s): Besma Ben Dhaou, Fatma Ben Dahmen, Zohra Aydi, Lilia Baili, Fatma Boussema, Lilia Rokbani

Journal: Tunis Med. 2013 Dec;91(12):737-9.

 

Last Updated: 24 Jan 2014

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[Renal AA amyloidosis during Langerhans' cell histiocytosis: case report].
 

Author(s): Mondher Ounissi, Hermine Danielle Fouda, Hafedh Hedri, Karima Boubaker, Samia Barbouch, Mohamed Mongi Bacha, Rym Goucha, Ezzeddine Abderrahim, Hedi Ben Maiz, Adel Kheder

Journal: Tunis Med. 2013 Oct;91(10):613-4.

 

Last Updated: 27 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Amyloidosis AA" returned 8 free, full-text review articles on human participants. First 3 results:

AA amyloidosis: basic knowledge, unmet needs and future treatments.
 

Author(s): Laura Obici, Giampaolo Merlini

Journal:

 

Systemic AA amyloidosis is a long-term complication of several chronic inflammatory disorders, including rheumatoid arthritis, ankylosing spondylitis, autoinflammatory syndromes, Crohn's disease, malignancies and conditions predisposing to recurrent infections. Organ damage results ...

Last Updated: 1 Jun 2012

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Recent insights into the pathogenesis of type AA amyloidosis.
 

Author(s): J C H van der Hilst

Journal:

 

The amyloidoses are a group of life-threatening diseases in which fibrils made of misfolded proteins are deposited in organs and tissues. The fibrils are stable, insoluble aggregates of precursor proteins that have adopted an antiparallel beta-sheet structure. In type AA, or reactive, ...

Last Updated: 15 Mar 2011

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Susceptibility to AA amyloidosis in rheumatic diseases: a critical overview.
 

Author(s): Laura Obici, Sara Raimondi, Francesca Lavatelli, Vittorio Bellotti, Giampaolo Merlini

Journal: Arthritis Rheum.. 2009 Oct;61(10):1435-40.

 

Last Updated: 14 Oct 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Sep 2014

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Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level
 

Status: Not yet recruiting

Condition Summary: Observational

 

Last Updated: 16 Aug 2010

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Safety and Effect of Doxycycline in Patients With Amyloidosis
 

Status: Recruiting

Condition Summary: Amyloidosis

 

Last Updated: 12 May 2013

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