Immune thrombocytopenia

Common Name(s)

Immune thrombocytopenia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Immune thrombocytopenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Immune thrombocytopenia" returned 224 free, full-text research articles on human participants. First 3 results:

Interleukin 27 inhibits cytotoxic T-lymphocyte-mediated platelet destruction in primary immune thrombocytopenia.
 

Author(s): Hai Zhou, Ji-Hua Qiu, Tong Wang, Ying-Yi Yu, Xue-Na Liu, Xin Li, Ya-Wen Wang, Yu Hou, Li-Zhen Li, Xin-Guang Liu, Ming Hou, Jun Peng

Journal: Blood. 2014 Nov;124(22):3316-9.

 

Cytotoxic T-lymphocyte (CTL)-mediated platelet destruction and aberrant cytokine profiles play important roles in the pathogenesis of primary immune thrombocytopenia (ITP). Interleukin-27 (IL-27) has pleiotropic immunomodulatory effects. However, the effect of IL-27 on CTL activity ...

Last Updated: 21 Nov 2014

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Atypical scleromyxedema with prominent nodular lesions associated with immune thrombocytopenia: an unusual presentation.
 

Author(s): Ingrid Lopez-Lerma, Andreu Fernandez-Codina, Helena Hilari, Berta Ferrer, Albert Selva-O'Callaghan, Vicente Garcia-Patos

Journal: J. Am. Acad. Dermatol.. 2014 Oct;71(4):e158-9.

 

Last Updated: 15 Sep 2014

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Health-related quality of life in children with newly diagnosed immune thrombocytopenia.
 

Author(s): Katja M J Heitink-Pollé, Lotte Haverman, Kim V Annink, Sarah J Schep, Masja de Haas, Marrie C A Bruin

Journal: Haematologica. 2014 Sep;99(9):1525-31.

 

Despite its generally transient and benign course, childhood immune thrombocytopenia has a large impact on health-related quality of life. Recently published guidelines state that quality of life should be taken into account while making decisions on management in childhood immune ...

Last Updated: 1 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Immune thrombocytopenia" returned 50 free, full-text review articles on human participants. First 3 results:

Helicobacter pylori-associated immune thrombocytopenia: clinical features and pathogenic mechanisms.
 

Author(s): Masataka Kuwana

Journal: World J. Gastroenterol.. 2014 Jan;20(3):714-23.

 

Immune thrombocytopenia (ITP) is an autoimmune disease mediated by anti-platelet autoantibodies. There is growing evidence that the eradication of Helicobacter pylori (H. pylori) effectively increases platelet count in a considerable proportion of ITP patients infected with this bacterium. ...

Last Updated: 27 Feb 2014

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Is anti-D immunoglobulin still a frontline treatment option for immune thrombocytopenia?
 

Author(s): Jenny M Despotovic, Cindy E Neunert

Journal: Hematology Am Soc Hematol Educ Program. 2013 ;2013():283-5.

 

A 5-year-old boy presents with platelet count of 2×10(9)/L and clinical and laboratory evidence of immune thrombocytopenia. He has epistaxis and oral mucosal bleeding. Complete blood count reveals isolated thrombocytopenia without any decline in hemoglobin and he is Rh+. You are ...

Last Updated: 9 Dec 2013

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Current management of immune thrombocytopenia.
 

Author(s): Cindy E Neunert

Journal: Hematology Am Soc Hematol Educ Program. 2013 ;2013():276-82.

 

Immune thrombocytopenia (ITP) is an autoimmune-mediated condition that results from antibody-mediated destruction of platelets and impaired megakaryocyte platelet production. ITP patients exhibit severe thrombocytopenia and are at risk for significant hemorrhage. Few randomized trials ...

Last Updated: 9 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

An Open Phase 3 Study of IV-Globulin SN Inj.10% to Treat Immune Thrombocytopenia
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia

 

Last Updated: 18 Mar 2015

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Recombinant Human Thrombopoietin (rhTPO) in Management of Immune Thrombocytopenia (ITP) in Pregnancy
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia; Pregnancy

 

Last Updated: 17 Oct 2014

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Last Updated: 12 Jun 2013

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