Immune thrombocytopenia

Common Name(s)

Immune thrombocytopenia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Immune thrombocytopenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Immune thrombocytopenia" returned 302 free, full-text research articles on human participants. First 3 results:

Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors.
 

Author(s): Mei Wu, Hongfeng Ge, Shue Li, Hailiang Chu, Shili Yang, Xiaoxing Sun, Zhenxia Zhou, Xiongpeng Zhu

Journal: J Immunol Res. 2015 ;2015():316351.

 

Mesenchymal stem cells are immunoregulation cells. IL-22 plays an important role in the pathogenesis of immune thrombocytopenia. However, the effects of mesenchymal stem cells on IL-22 production in patients with immune thrombocytopenia remain unclear. Flow cytometry analyzed immunophenotypes ...

Last Updated: 27 Oct 2015

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Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
 

Author(s): Zheng Cai, Serge V Yarovoi, Zhiqiang Zhu, Lubica Rauova, Vincent Hayes, Tatiana Lebedeva, Qun Liu, Mortimer Poncz, Gowthami Arepally, Douglas B Cines, Mark I Greene

Journal:

 

Heparin-induced thrombocytopenia (HIT) is an autoimmune thrombotic disorder caused by immune complexes containing platelet factor 4 (PF4), antibodies to PF4 and heparin or cellular glycosaminoglycans (GAGs). Here we solve the crystal structures of the: (1) PF4 tetramer/fondaparinux ...

Last Updated: 22 Sep 2015

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Anaphylaxis to Intravenous Methylprednisolone Hemisuccinate in a Patient With Immune Thrombocytopenia.
 

Author(s): F Alvarez Caro, V García González, J González García, R García Mozo, B García Norniella, A Gómez Farpó

Journal: J Investig Allergol Clin Immunol. 2015 ;25(4):309-10.

 

Last Updated: 27 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Immune thrombocytopenia" returned 56 free, full-text review articles on human participants. First 3 results:

Clinical and laboratory predictors of chronic immune thrombocytopenia in children: a systematic review and meta-analysis.
 

Author(s): Katja M J Heitink-Pollé, Joyce Nijsten, Chantal W B Boonacker, Masja de Haas, Marrie C A Bruin

Journal: Blood. 2014 Nov;124(22):3295-307.

 

Childhood immune thrombocytopenia (ITP) is a rare autoimmune bleeding disorder. Most children recover within 6 to 12 months, but individual course is difficult to predict. We performed a systematic review and meta-analysis to identify predictors of chronic ITP. We found 1399 articles; ...

Last Updated: 21 Nov 2014

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T cell immune abnormalities in immune thrombocytopenia.
 

Author(s): Xuebin Ji, Liping Zhang, Jun Peng, Ming Hou

Journal:

 

Immune thrombocytopenia is an autoimmune disease with abnormal T cell immunity. Cytotoxic T cells, abnormal T regulatory cells, helper T cell imbalance, megakaryocyte maturation abnormalities and abnormal T cell anergy are involved in the pathogenesis of this condition. The loss of ...

Last Updated: 28 Apr 2015

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Novel treatments for immune thrombocytopenia.
 

Author(s): Andrew Shih, Ishac Nazi, John G Kelton, Donald M Arnold

Journal: Presse Med. 2014 Apr;43(4 Pt 2):e87-95.

 

Primary immune thrombocytopenia (ITP) is caused by platelet autoantibodies and T-cell dysregulation. Both platelets and their precursor megakaryocytes may be targeted leading to platelet destruction and underproduction. Current treatments for ITP are inadequate since they do not reverse ...

Last Updated: 15 Apr 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Multi-center Study of Low-dose Decitabine for the Treatment of Immune Thrombocytopenia
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia

 

Last Updated: 21 Apr 2016

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Recombinant Human Thrombopoietin (rhTPO) in Management of Immune Thrombocytopenia (ITP) in Pregnancy
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia; Pregnancy

 

Last Updated: 18 Apr 2016

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Last Updated: 31 Jul 2015

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