Idiopathic thrombocytopenic purpura

Common Name(s)

Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic thrombocytopenic purpura" returned 326 free, full-text research articles on human participants. First 3 results:

An autopsy case of myocardial infarction due to idiopathic thrombotic thrombocytopenic purpura.
 

Author(s): Takashi Tasaki, Sohsuke Yamada, Atsunori Nabeshima, Hirotsugu Noguchi, Aya Nawata, Masanori Hisaoka, Yasuyuki Sasaguri, Toshiyuki Nakayama

Journal:

 

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder characterized by systemic platelet-von Willebrand factor aggregation, organ ischemia and profound thrombocytopenia. In this report, we describe an autopsy case of a 77-year-old Japanese man diagnosed with idiopathic ...

Last Updated: 29 May 2015

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Successful prevention of exacerbation of thrombocytopenia in a pregnant patient with idiopathic thrombocytopenic purpura by anticoagulation treatment.
 

Author(s): Michi Hisano, Nobuhiro Tsukada, Haruhiko Sago, Koushi Yamaguchi

Journal:

 

Corticosteroid or intravenous immunoglobulin is used in the management of idiopathic thrombocytopenic purpura during pregnancy.

Last Updated: 18 Apr 2015

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Idiopathic thrombocytopenic purpura in children: a 10 years experience at tertiary care hospital.
 

Author(s): Muhammad Matloob Alam

Journal: J Pak Med Assoc. 2014 Dec;64(12):1358-62.

 

To evaluate presenting features, treatment modalities and response to therapy in children with idiopathic thrombocytopenic purpura.

Last Updated: 6 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic thrombocytopenic purpura" returned 25 free, full-text review articles on human participants. First 3 results:

Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP).
 

Author(s): D Boyers, X Jia, M Crowther, D Jenkinson, C Fraser, G Mowatt

Journal: Health Technol Assess. 2011 May;15 Suppl 1():23-32.

 

This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of eltrombopag for the treatment of adults with chronic idiopathic (immune) thrombocytopenic purpura (ITP), based on a review of the manufacturer's submission ...

Last Updated: 25 May 2011

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The European Medicines Agency review of eltrombopag (Revolade) for the treatment of adult chronic immune (idiopathic) thrombocytopenic purpura: summary of the scientific assessment of the Committee for Medicinal Products for Human Use.
 

Author(s): Maria Nieto, Gonzalo Calvo, Ian Hudson, Peter Feldschreiber, David Brown, Ching Cheng Lee, Geoffrey Lay, Anna Valeri, Eric Abadie, Angela Thomas, Francesco Pignatti

Journal: Haematologica. 2011 Sep;96(9):e33-40.

 

On 11(th) March 2010, the European Commission issued a marketing authorization valid throughout the European Union for Revolade for the treatment of adult chronic immune (idiopathic) thrombocytopenic purpura. Revolade is an orphan medicinal product indicated for splenectomized patients ...

Last Updated: 1 Sep 2011

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Idiopathic thrombocytopenic purpura and coronary artery disease: comparison between coronary artery bypass grafting and percutaneous coronary intervention.
 

Author(s): Antonio Russo, Marina Cannizzo, Gabriele Ghetti, Elena Barbaresi, Elisa Filippini, Salvatore Specchia, Angelo Branzi

Journal: Interact Cardiovasc Thorac Surg. 2011 Aug;13(2):153-7.

 

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a low platelet count and an increased risk of bleeding. At the same time, ITP patients present an increased risk of thrombosis and atherosclerosis related to the high presence of haemostatic factors ...

Last Updated: 21 Jul 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cohort of Children With Acute Immune or Idiopathic Thrombocytopenic Purpura (ITP) : a Prospective Study in Pays De La Loire
 

Status: Not yet recruiting

Condition Summary: Acute Idiopathic Thrombocytopenic Purpura

 

Last Updated: 29 May 2006

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Safety and Efficacy Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients
 

Status: Recruiting

Condition Summary: Chronic Idiopathic Thrombocytopenic Purpura

 

Last Updated: 22 Nov 2015

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Recombinant Human Thrombopoietin in Combination With Rituximab in Immune Thrombocytopenia (ITP)
 

Status: Recruiting

Condition Summary: Purpura; Idiopathic Thrombocytopenic Purpura

 

Last Updated: 20 Jan 2012

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