Idiopathic thrombocytopenic purpura

Common Name(s)

Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic thrombocytopenic purpura" returned 341 free, full-text research articles on human participants. First 3 results:

A Case Report of an Elderly Woman With Thrombocytopenia and Bilateral Lung Infiltrates: A Rare Association Between Diffuse Alveolar Hemorrhage and Idiopathic Thrombocytopenic Purpura.
 

Author(s): Hafiz Rizwan Talib Hashmi, Sindhaghatta Venkatram, Gilda Diaz-Fuentes

Journal: Medicine (Baltimore). 2015 Dec;94(50):e2235.

 

Etiologies for diffuse alveolar hemorrhage are wide and range from infectious to vasculitis and malignant processes. Idiopathic thrombocytopenic purpura is an autoimmune disorder characterized by persistent thrombocytopenia, with a relatively indolent course in young patients, but ...

Last Updated: 19 Dec 2015

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Is Helicobacter pylori infection a risk factor for idiopathic thrombocytopenic purpura in children?
 

Author(s): Alireza Abdollahi, Saeed Shoar, Shadi Ghasemi, Oloomi-Yazdi Zohreh

Journal: Ann Afr Med. ;14(4):177-81.

 

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune bleeding disorder, which occurs as a result of autoantibodies attachment to the platelets surface and subsequent destruction. Several organisms can mimic features of human antigens (Ags) and induce autoantibody production. ...

Last Updated: 16 Oct 2015

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Efficacy of standard dose rituximab for refractory idiopathic thrombocytopenic purpura in children.
 

Author(s): W-J Dai, R-R Zhang, X-C Yang, Y-F Yuan

Journal: Eur Rev Med Pharmacol Sci. 2015 Jul;19(13):2379-83.

 

The present study intends to investigate the efficacy and safety of standard dose rituximab for treatment of refractory idiopathic thrombocytopenic purpura (RITP) in children.

Last Updated: 28 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic thrombocytopenic purpura" returned 27 free, full-text review articles on human participants. First 3 results:

Recurrent acute coronary syndrome and restenosis after percutaneous coronary intervention in a patient with idiopathic thrombocytopenic purpura: a case report and literature review.
 

Author(s): Ge Li-Sha, Chen Peng, Li Yue-Chun

Journal:

 

Platelets play a pivotal role in the pathogenesis of acute coronary syndrome (ACS) and acute and chronic complications following percutaneous coronary intervention (PCI). Platelet inhibition is a cornerstone in the management of these patients. Idiopathic thrombocytopenic purpura ...

Last Updated: 19 Sep 2015

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Massive subretinal and vitreous haemorrhages at presentation in idiopathic thrombocytopenic purpura: report of a case and review of literature.
 

Author(s): Neha Goel, Supriya Arora, Pooja Jain, Basudeb Ghosh

Journal: Clin Exp Optom. 2014 May;97(3):270-3.

 

A 21-year-old woman presented with acute decreased vision due to massive subretinal haemorrhage with macular exudation in the right eye and vitreous haemorrhage in the left eye. Haematological work-up revealed thrombocytopenia (platelets 14,000/μl) with anaemia (haemoglobin 6.3 gm/100 ml). ...

Last Updated: 28 Apr 2014

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Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP).
 

Author(s): D Boyers, X Jia, M Crowther, D Jenkinson, C Fraser, G Mowatt

Journal: Health Technol Assess. 2011 May;15 Suppl 1():23-32.

 

This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of eltrombopag for the treatment of adults with chronic idiopathic (immune) thrombocytopenic purpura (ITP), based on a review of the manufacturer's submission ...

Last Updated: 25 May 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cohort of Children With Acute Immune or Idiopathic Thrombocytopenic Purpura (ITP) : a Prospective Study in Pays De La Loire
 

Status: Not yet recruiting

Condition Summary: Acute Idiopathic Thrombocytopenic Purpura

 

Last Updated: 29 May 2006

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Safety and Efficacy Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients
 

Status: Recruiting

Condition Summary: Chronic Idiopathic Thrombocytopenic Purpura

 

Last Updated: 22 Nov 2015

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Study of Doxil in the Treatment of Patients With Refractory Idiopathic Thrombocytopenic Purpura
 

Status: Recruiting

Condition Summary: Autoimmune Thrombocytopenic Purpura

 

Last Updated: 23 Jun 2005

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