Idiopathic thrombocytopenic purpura

Common Name(s)

Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic thrombocytopenic purpura" returned 342 free, full-text research articles on human participants. First 3 results:

Presence of Antiphospholipid Antibodies as a Risk Factor for Thrombotic Events in Patients with Connective Tissue Diseases and Idiopathic Thrombocytopenic Purpura.
 

Author(s): Koji Habe, Hideo Wada, Takeshi Matsumoto, Kohshi Ohishi, Makoto Ikejiri, Kimiko Matsubara, Tatsuhiko Morioka, Yuki Kamimoto, Tomoaki Ikeda, Naoyuki Katayama, Hitoshi Mizutani

Journal: Intern. Med.. 2016 ;55(6):589-95.

 

Antiphospholipid syndrome (APS) is a well-known complication of habitual abortion and/or thrombosis and is frequently associated with autoimmune diseases.

Last Updated: 17 Mar 2016

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Primary Percutaneous Coronary Intervention by a Stentless Technique for Acute Myocardial Infarction with Idiopathic Thrombocytopenic Purpura: A Case Report and Review of the Literature.
 

Author(s): Susumu Fujino, Satoru Niwa, Kensuke Fujioka, Tomohito Mabuchi, Yoshihiro Noji, Masato Yamaguchi, Takahiko Aoyama

Journal: Intern. Med.. 2016 ;55(2):147-52.

 

A 78-year-old man who had been diagnosed with idiopathic thrombocytopenic purpura (ITP) was admitted to our hospital with chest pain, cold sweating and nausea. An electrocardiogram and echocardiogram revealed an ST elevated acute lateral myocardial infarction. He underwent an immediate ...

Last Updated: 19 Jan 2016

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Peliosis hepatis presenting with massive hepatomegaly in a patient with idiopathic thrombocytopenic purpura.
 

Author(s): Sun Bean Kim, Do Kyung Kim, Sun Jeong Byun, Ji Hye Park, Jin Young Choi, Young Nyun Park, Do Young Kim

Journal: Clin Mol Hepatol. 2015 Dec;21(4):387-92.

 

Peliosis hepatis is a rare condition that can cause hepatic hemorrhage, rupture, and ultimately liver failure. Several authors have reported that peliosis hepatis develops in association with chronic wasting disease or prolonged use of anabolic steroids or oral contraceptives. In ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic thrombocytopenic purpura" returned 27 free, full-text review articles on human participants. First 3 results:

Recurrent acute coronary syndrome and restenosis after percutaneous coronary intervention in a patient with idiopathic thrombocytopenic purpura: a case report and literature review.
 

Author(s): Ge Li-Sha, Chen Peng, Li Yue-Chun

Journal:

 

Platelets play a pivotal role in the pathogenesis of acute coronary syndrome (ACS) and acute and chronic complications following percutaneous coronary intervention (PCI). Platelet inhibition is a cornerstone in the management of these patients. Idiopathic thrombocytopenic purpura ...

Last Updated: 19 Sep 2015

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Massive subretinal and vitreous haemorrhages at presentation in idiopathic thrombocytopenic purpura: report of a case and review of literature.
 

Author(s): Neha Goel, Supriya Arora, Pooja Jain, Basudeb Ghosh

Journal: Clin Exp Optom. 2014 May;97(3):270-3.

 

A 21-year-old woman presented with acute decreased vision due to massive subretinal haemorrhage with macular exudation in the right eye and vitreous haemorrhage in the left eye. Haematological work-up revealed thrombocytopenia (platelets 14,000/μl) with anaemia (haemoglobin 6.3 gm/100 ml). ...

Last Updated: 28 Apr 2014

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Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP).
 

Author(s): D Boyers, X Jia, M Crowther, D Jenkinson, C Fraser, G Mowatt

Journal: Health Technol Assess. 2011 May;15 Suppl 1():23-32.

 

This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of eltrombopag for the treatment of adults with chronic idiopathic (immune) thrombocytopenic purpura (ITP), based on a review of the manufacturer's submission ...

Last Updated: 25 May 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients
 

Status: Recruiting

Condition Summary: Chronic Idiopathic Thrombocytopenic Purpura

 

Last Updated: 22 Nov 2015

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Last Updated: 4 Feb 2015

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A Multi-center Study of Low-dose Decitabine for the Treatment of Immune Thrombocytopenia
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia

 

Last Updated: 26 Jul 2016

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