Idiopathic thrombocytopenic purpura

Common Name(s)

Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic thrombocytopenic purpura" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic thrombocytopenic purpura" returned 257 free, full-text research articles on human participants. First 3 results:

Renal transplantation in idiopathic thrombocytopenic purpura.
 

Author(s): Kamal V Kanodia, Aruna V Vanikar, Pankaj R Shah, H L Trivedi

Journal: Saudi J Kidney Dis Transpl. 2013 Jul;24(4):793-4.

 

Last Updated: 2 Jul 2013

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[Role of Helicobacter pylori infection in the pathogenesis and clinical outcome of childhood acute idiopathic thrombocytopenic purpura].
 

Author(s): Jie Lu, Chun-mei Wang, Song-tao Xu, Li-li Song, Xiao-ming Zhao, Qun-ying Wang, Guang-yao Sheng

Journal: Zhonghua Xue Ye Xue Za Zhi. 2013 Jan;34(1):41-4.

 

To investigate the role of Helicobacter pylori (Hp) and its products cytotoxin-associated protein (Cag A), vacuolating cytotoxin (VacA) in childhood acute idiopathic thrombocytopenic purpura (aITP), to evaluate the effect of Hp on their clinical outcome.

Last Updated: 19 Apr 2013

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Idiopathic thrombocytopenic purpura associated with splenic tuberculosis: case report.
 

Author(s): Mehmet Sinan Dal, Tuba Dal, Recep Tekin, Erdal Bodakçi, Yakup Düzköprü, Mehmet Orhan Ayyildiz

Journal: Infez Med. 2013 Mar;21(1):50-5.

 

Tuberculosis is still one of the most prevalent and fatal infectious diseases in spite of considerable improvements in medical science. Splenic tuberculosis is a rare form of extrapulmonary tuberculosis. There are limited numbers of cases in which immune thrombocytopenia is associated ...

Last Updated: 25 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic thrombocytopenic purpura" returned 22 free, full-text review articles on human participants. First 3 results:

Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP).
 

Author(s): D Boyers, X Jia, M Crowther, D Jenkinson, C Fraser, G Mowatt

Journal: Health Technol Assess. 2011 May;15 Suppl 1():23-32.

 

This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of eltrombopag for the treatment of adults with chronic idiopathic (immune) thrombocytopenic purpura (ITP), based on a review of the manufacturer's submission ...

Last Updated: 25 May 2011

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The European Medicines Agency review of eltrombopag (Revolade) for the treatment of adult chronic immune (idiopathic) thrombocytopenic purpura: summary of the scientific assessment of the Committee for Medicinal Products for Human Use.
 

Author(s): Maria Nieto, Gonzalo Calvo, Ian Hudson, Peter Feldschreiber, David Brown, Ching Cheng Lee, Geoffrey Lay, Anna Valeri, Eric Abadie, Angela Thomas, Francesco Pignatti

Journal: Haematologica. 2011 Sep;96(9):e33-40.

 

On 11(th) March 2010, the European Commission issued a marketing authorization valid throughout the European Union for Revolade for the treatment of adult chronic immune (idiopathic) thrombocytopenic purpura. Revolade is an orphan medicinal product indicated for splenectomized patients ...

Last Updated: 1 Sep 2011

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Idiopathic thrombocytopenic purpura and coronary artery disease: comparison between coronary artery bypass grafting and percutaneous coronary intervention.
 

Author(s): Antonio Russo, Marina Cannizzo, Gabriele Ghetti, Elena Barbaresi, Elisa Filippini, Salvatore Specchia, Angelo Branzi

Journal: Interact Cardiovasc Thorac Surg. 2011 Aug;13(2):153-7.

 

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a low platelet count and an increased risk of bleeding. At the same time, ITP patients present an increased risk of thrombosis and atherosclerosis related to the high presence of haemostatic factors ...

Last Updated: 21 Jul 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cohort of Children With Acute Immune or Idiopathic Thrombocytopenic Purpura (ITP) : a Prospective Study in Pays De La Loire
 

Status: Not yet recruiting

Condition Summary: Acute Idiopathic Thrombocytopenic Purpura

 

Last Updated: 29 May 2006

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MONICA-SC: A Study to Evaluate the Efficacy, Safety and Tolerability of Blisibimod (A-623) Administration in Subjects With ITP
 

Status: Not yet recruiting

Condition Summary: Immune Thrombocytopenic Purpura; Idiopathic Thrombocytopenic Purpura

 

Last Updated: 5 Aug 2014

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Study of Doxil in the Treatment of Patients With Refractory Idiopathic Thrombocytopenic Purpura
 

Status: Recruiting

Condition Summary: Autoimmune Thrombocytopenic Purpura

 

Last Updated: 23 Jun 2005

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