Idiopathic adolescent scoliosis

Common Name(s)

Idiopathic adolescent scoliosis

Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "s" or "C" shape, and the bones of the spine become slightly twisted or rotated. In many cases, the abnormal spinal curve is stable; however, in some children, the curve becomes more severe over time (progressive). For unknown reasons, severe and progressive curves occur more frequently in girls than in boys. The cause of adolescent idiopathic scoliosis is unknown. It is likely that there are both genetic and environmental factors involved. Treatment may include observation, bracing and/or surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic adolescent scoliosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic adolescent scoliosis" returned 229 free, full-text research articles on human participants. First 3 results:

Intraoperative blood loss in female patients with adolescent idiopathic scoliosis during different phases of the menstrual cycle.
 

Author(s): Chao Li, Yang Xie, Zhikun Li, Mingyuan Yang, Xiaofei Sun, Jianping Fan, Honglei Yi Xiaodong Zhu, Chuanfeng Wang, Ming Li

Journal:

 

The vast majority of AIS patients who require surgical intervention are women. Blood loss is a major concern during the operation.

Last Updated: 26 Nov 2014

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Postoperative shoulder imbalance in Lenke Type 1A adolescent idiopathic scoliosis and related factors.
 

Author(s): Morio Matsumoto, Kota Watanabe, Noriaki Kawakami, Taichi Tsuji, Koki Uno, Teppei Suzuki, Manabu Ito, Haruhisa Yanagida, Shohei Minami, Tsutomu Akazawa

Journal:

 

The purpose of this study was to investigate the occurrence and factors associated with postoperative shoulder imbalance (PSI) in Lenke type 1A curve.

Last Updated: 11 Nov 2014

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Transforming growth factor-beta (TGF- β) signaling in paravertebral muscles in juvenile and adolescent idiopathic scoliosis.
 

Author(s): Roman Nowak, Magdalena Kwiecien, Magdalena Tkacz, Urszula Mazurek

Journal: Biomed Res Int. 2014 ;2014():594287.

 

Most researchers agree that idiopathic scoliosis (IS) is a multifactorial disease influenced by complex genetic and environmental factors. The onset of the spinal deformity that determines the natural course of the disease, usually occurs in the juvenile or adolescent period. Transforming ...

Last Updated: 14 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic adolescent scoliosis" returned 26 free, full-text review articles on human participants. First 3 results:

[Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature].
 

Author(s): Maria Isabel Bonilla Carrasco, Maria Carmen Solano Ruiz

Journal: Rev Esc Enferm USP. 2014 Aug;48(4):748-58.

 

To learn about the experiences of adolescents diagnosed with idiopathic scoliosis.

Last Updated: 23 Oct 2014

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A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis.
 

Author(s): Gene Chi Wai Man, Man Gene Chi Wai, William Wei Jun Wang, Wang William Wei Jun, Annie Po Yee Yim, Yim Annie Po Yee, Jack Ho Wong, Wong Jack Ho, Tzi Bun Ng, Ng Tzi Bun, Tsz Ping Lam, Lam Tsz Ping, Simon Kwong Man Lee, Lee Simon Kwong Man, Bobby Kin Wah Ng, Ng Bobby Kin Wah, Chi Chiu Wang, Wang Chi Chiu, Yong Qiu, Qiu Yong, Chun Yiu Cheng, Cheng Jack Chun Yiu

Journal:

 

Adolescent idiopathic scoliosis (AIS) is a common orthopedic disorder of unknown etiology and pathogenesis. Melatonin and melatonin pathway dysfunction has been widely suspected to play an important role in the pathogenesis. Many different types of animal models have been developed ...

Last Updated: 20 Sep 2014

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How 'idiopathic' is adolescent idiopathic scoliosis? A systematic review on associated abnormalities.
 

Author(s): Tom P C Schlösser, Geert J M G van der Heijden, Anne L Versteeg, René M Castelein

Journal:

 

Despite more than a century of dedicated research, the etiology and pathogenesis of adolescent idiopathic scoliosis (AIS) remain unclear. By definition, 'idiopathic' implies an unknown cause. Nevertheless, many abnormalities concomitant to AIS have been described, often with the suggestion ...

Last Updated: 13 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis

 

Last Updated: 8 Jun 2015

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Safety and Effectiveness Evaluation of the Minimal Invasive Deformity Correction (MID-C) System in Adolescent Idiopathic Scoliosis (AIS)
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis (AIS)

 

Last Updated: 13 Jan 2015

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Anesthetic Optimization in Scoliosis Surgery
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis; Respiratory Depression; Postoperative Pain

 

Last Updated: 23 Jun 2015

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