Idiopathic adolescent scoliosis

Common Name(s)

Idiopathic adolescent scoliosis

Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "s" or "C" shape, and the bones of the spine become slightly twisted or rotated. In many cases, the abnormal spinal curve is stable; however, in some children, the curve becomes more severe over time (progressive). For unknown reasons, severe and progressive curves occur more frequently in girls than in boys. The cause of adolescent idiopathic scoliosis is unknown. It is likely that there are both genetic and environmental factors involved. Treatment may include observation, bracing and/or surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic adolescent scoliosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic adolescent scoliosis" returned 287 free, full-text research articles on human participants. First 3 results:

Comparative Analysis of Interval, Skipped, and Key-vertebral Pedicle Screw Strategies for Correction in Patients With Lenke Type 1 Adolescent Idiopathic Scoliosis.
 

Author(s): Fei Wang, Xi-Ming Xu, Yanghu Lu, Xian-Zhao Wei, Xiao-Dong Zhu, Ming Li

Journal: Medicine (Baltimore). 2016 Mar;95(10):e3021.

 

Pedicle screw constructs have become the mainstay for surgical correction in patients with spinal deformities. To reduce or avoid the risk of pedicle screw-based complications and to decrease the costs associated with pedicle screw instrumentation, some authors have introduced interval, ...

Last Updated: 11 Mar 2016

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Body composition in males with adolescent idiopathic scoliosis: a case-control study with dual-energy X-ray absorptiometry.
 

Author(s): Weijun Wang, Zhiwei Wang, Zezhang Zhu, Feng Zhu, Yong Qiu

Journal:

 

In contrast to the well-characterized body growth and development of females with adolescent idiopathic scoliosis (AIS), the pubertal growth pattern of male patients has not been well-documented. Recently, significantly lower body weight (BW) and body mass index (BMI) were reported ...

Last Updated: 1 Mar 2016

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Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.
 

Author(s): Long Guo, Hiroshi Yamashita, Ikuyo Kou, Aki Takimoto, Makiko Meguro-Horike, Shin-ichi Horike, Tetsushi Sakuma, Shigenori Miura, Taiji Adachi, Takashi Yamamoto, Shiro Ikegawa, Yuji Hiraki, Chisa Shukunami

Journal:

 

Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study. Here, we characterized the associated non-coding variant and investigated the function of these genes. A chromosome ...

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic adolescent scoliosis" returned 29 free, full-text review articles on human participants. First 3 results:

Effects of Exercise on Spinal Deformities and Quality of Life in Patients with Adolescent Idiopathic Scoliosis.
 

Author(s): Shahnawaz Anwer, Ahmad Alghadir, Md Abu Shaphe, Dilshad Anwar

Journal: Biomed Res Int. 2015 ;2015():123848.

 

This systematic review was conducted to examine the effects of exercise on spinal deformities and quality of life in patients with adolescent idiopathic scoliosis (AIS).

Last Updated: 20 Nov 2015

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The Association of rs4753426 Polymorphism in the Melatonin Receptor 1B (MTNR1B) Gene and Susceptibility to Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis.
 

Author(s): Peng Yang, Hao Liu, Jun Lin, Huilin Yang

Journal: Pain Physician. ;18(5):419-31.

 

Adolescent idiopathic scoliosis (AIS) is a tridimensional structural deformity of the spine that may deteriorate progressively, leading to significant functional limitations and pain problems. Several previous studies have implicated the rs4753426 single nucleotide polymorphism in ...

Last Updated: 3 Oct 2015

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[Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature].
 

Author(s): Maria Isabel Bonilla Carrasco, Maria Carmen Solano Ruiz

Journal: Rev Esc Enferm USP. 2014 Aug;48(4):748-58.

 

To learn about the experiences of adolescents diagnosed with idiopathic scoliosis.

Last Updated: 23 Oct 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy of Physiotherapeutic Scoliosis Specific Exercises in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Scoliosis Idiopathic Adolescent

 

Last Updated: 16 Nov 2016

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Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis

 

Last Updated: 15 Jun 2016

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Safety and Effectiveness Evaluation of the Minimal Invasive Deformity Correction (MID-C) System in Adolescent Idiopathic Scoliosis (AIS)
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis (AIS)

 

Last Updated: 13 Jan 2015

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