Idiopathic adolescent scoliosis

Common Name(s)

Idiopathic adolescent scoliosis

Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "s" or "C" shape, and the bones of the spine become slightly twisted or rotated. In many cases, the abnormal spinal curve is stable; however, in some children, the curve becomes more severe over time (progressive). For unknown reasons, severe and progressive curves occur more frequently in girls than in boys. The cause of adolescent idiopathic scoliosis is unknown. It is likely that there are both genetic and environmental factors involved. Treatment may include observation, bracing and/or surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic adolescent scoliosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic adolescent scoliosis" returned 282 free, full-text research articles on human participants. First 3 results:

Comparative Analysis of Interval, Skipped, and Key-vertebral Pedicle Screw Strategies for Correction in Patients With Lenke Type 1 Adolescent Idiopathic Scoliosis.
 

Author(s): Fei Wang, Xi-Ming Xu, Yanghu Lu, Xian-Zhao Wei, Xiao-Dong Zhu, Ming Li

Journal: Medicine (Baltimore). 2016 Mar;95(10):e3021.

 

Pedicle screw constructs have become the mainstay for surgical correction in patients with spinal deformities. To reduce or avoid the risk of pedicle screw-based complications and to decrease the costs associated with pedicle screw instrumentation, some authors have introduced interval, ...

Last Updated: 11 Mar 2016

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Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.
 

Author(s): Long Guo, Hiroshi Yamashita, Ikuyo Kou, Aki Takimoto, Makiko Meguro-Horike, Shin-ichi Horike, Tetsushi Sakuma, Shigenori Miura, Taiji Adachi, Takashi Yamamoto, Shiro Ikegawa, Yuji Hiraki, Chisa Shukunami

Journal:

 

Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study. Here, we characterized the associated non-coding variant and investigated the function of these genes. A chromosome ...

Last Updated: 29 Jan 2016

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Effect of a Traditional Chinese Medicine combined therapy on adolescent idiopathic scoliosis: a randomized controlled trial.
 

Author(s): Hui Wei, Jinyuan Xu, Zhong Jiang, Shuliang Ye, Hongquan Song, Xitao Ning, Huanmin Huang, Wei Chen, Jianwei Pei, Nengyi Jiang, Shao Chen, Honggen Du

Journal: J Tradit Chin Med. 2015 Oct;35(5):514-9.

 

To evaluate the effectiveness of a combined Traditional Chinese Medicine (TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.

Last Updated: 20 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic adolescent scoliosis" returned 28 free, full-text review articles on human participants. First 3 results:

The Association of rs4753426 Polymorphism in the Melatonin Receptor 1B (MTNR1B) Gene and Susceptibility to Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis.
 

Author(s): Peng Yang, Hao Liu, Jun Lin, Huilin Yang

Journal: Pain Physician. ;18(5):419-31.

 

Adolescent idiopathic scoliosis (AIS) is a tridimensional structural deformity of the spine that may deteriorate progressively, leading to significant functional limitations and pain problems. Several previous studies have implicated the rs4753426 single nucleotide polymorphism in ...

Last Updated: 3 Oct 2015

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[Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature].
 

Author(s): Maria Isabel Bonilla Carrasco, Maria Carmen Solano Ruiz

Journal: Rev Esc Enferm USP. 2014 Aug;48(4):748-58.

 

To learn about the experiences of adolescents diagnosed with idiopathic scoliosis.

Last Updated: 23 Oct 2014

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A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis.
 

Author(s): Gene Chi Wai Man, Man Gene Chi Wai, William Wei Jun Wang, Wang William Wei Jun, Annie Po Yee Yim, Yim Annie Po Yee, Jack Ho Wong, Wong Jack Ho, Tzi Bun Ng, Ng Tzi Bun, Tsz Ping Lam, Lam Tsz Ping, Simon Kwong Man Lee, Lee Simon Kwong Man, Bobby Kin Wah Ng, Ng Bobby Kin Wah, Chi Chiu Wang, Wang Chi Chiu, Yong Qiu, Qiu Yong, Chun Yiu Cheng, Cheng Jack Chun Yiu

Journal:

 

Adolescent idiopathic scoliosis (AIS) is a common orthopedic disorder of unknown etiology and pathogenesis. Melatonin and melatonin pathway dysfunction has been widely suspected to play an important role in the pathogenesis. Many different types of animal models have been developed ...

Last Updated: 20 Sep 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis

 

Last Updated: 15 Jun 2016

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Safety and Effectiveness Evaluation of the Minimal Invasive Deformity Correction (MID-C) System in Adolescent Idiopathic Scoliosis (AIS)
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis (AIS)

 

Last Updated: 13 Jan 2015

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Anesthetic Optimization in Scoliosis Surgery
 

Status: Recruiting

Condition Summary: Adolescent Idiopathic Scoliosis; Respiratory Depression; Postoperative Pain

 

Last Updated: 21 Jun 2016

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