Idiopathic adolescent scoliosis

Common Name(s)

Idiopathic adolescent scoliosis

Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "s" or "C" shape, and the bones of the spine become slightly twisted or rotated. In many cases, the abnormal spinal curve is stable; however, in some children, the curve becomes more severe over time (progressive). For unknown reasons, severe and progressive curves occur more frequently in girls than in boys. The cause of adolescent idiopathic scoliosis is unknown. It is likely that there are both genetic and environmental factors involved. Treatment may include observation, bracing and/or surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Idiopathic adolescent scoliosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Idiopathic adolescent scoliosis" returned 277 free, full-text research articles on human participants. First 3 results:

Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.
 

Author(s): Long Guo, Hiroshi Yamashita, Ikuyo Kou, Aki Takimoto, Makiko Meguro-Horike, Shin-ichi Horike, Tetsushi Sakuma, Shigenori Miura, Taiji Adachi, Takashi Yamamoto, Shiro Ikegawa, Yuji Hiraki, Chisa Shukunami

Journal:

 

Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study. Here, we characterized the associated non-coding variant and investigated the function of these genes. A chromosome ...

Last Updated: 29 Jan 2016

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Effect of a Traditional Chinese Medicine combined therapy on adolescent idiopathic scoliosis: a randomized controlled trial.
 

Author(s): Hui Wei, Jinyuan Xu, Zhong Jiang, Shuliang Ye, Hongquan Song, Xitao Ning, Huanmin Huang, Wei Chen, Jianwei Pei, Nengyi Jiang, Shao Chen, Honggen Du

Journal: J Tradit Chin Med. 2015 Oct;35(5):514-9.

 

To evaluate the effectiveness of a combined Traditional Chinese Medicine (TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.

Last Updated: 20 Nov 2015

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Sagittal Balance in Adolescent Idiopathic Scoliosis: A Radiographic Study of Spinopelvic Compensation After Selective Posterior Fusion of Thoracolumbar/Lumbar (Lenke 5C) Curves.
 

Author(s): Xi-Ming Xu, Fei Wang, Xiao-Yi Zhou, Zi-Xuan Liu, Xian-Zhao Wei, Yu-Shu Bai, Ming Li

Journal: Medicine (Baltimore). 2015 Nov;94(45):e1995.

 

The relationship between spinal sagittal alignment and pelvic parameters is well known in adolescent idiopathic scoliosis. However, few studies have reported the sagittal spinopelvic relationship after selective posterior fusion of thoracolumbar/lumbar (TL/L) curves. We evaluated ...

Last Updated: 12 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Idiopathic adolescent scoliosis" returned 26 free, full-text review articles on human participants. First 3 results:

[Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature].
 

Author(s): Maria Isabel Bonilla Carrasco, Maria Carmen Solano Ruiz

Journal: Rev Esc Enferm USP. 2014 Aug;48(4):748-58.

 

To learn about the experiences of adolescents diagnosed with idiopathic scoliosis.

Last Updated: 23 Oct 2014

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A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis.
 

Author(s): Gene Chi Wai Man, Man Gene Chi Wai, William Wei Jun Wang, Wang William Wei Jun, Annie Po Yee Yim, Yim Annie Po Yee, Jack Ho Wong, Wong Jack Ho, Tzi Bun Ng, Ng Tzi Bun, Tsz Ping Lam, Lam Tsz Ping, Simon Kwong Man Lee, Lee Simon Kwong Man, Bobby Kin Wah Ng, Ng Bobby Kin Wah, Chi Chiu Wang, Wang Chi Chiu, Yong Qiu, Qiu Yong, Chun Yiu Cheng, Cheng Jack Chun Yiu

Journal:

 

Adolescent idiopathic scoliosis (AIS) is a common orthopedic disorder of unknown etiology and pathogenesis. Melatonin and melatonin pathway dysfunction has been widely suspected to play an important role in the pathogenesis. Many different types of animal models have been developed ...

Last Updated: 20 Sep 2014

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How 'idiopathic' is adolescent idiopathic scoliosis? A systematic review on associated abnormalities.
 

Author(s): Tom P C Schlösser, Geert J M G van der Heijden, Anne L Versteeg, René M Castelein

Journal:

 

Despite more than a century of dedicated research, the etiology and pathogenesis of adolescent idiopathic scoliosis (AIS) remain unclear. By definition, 'idiopathic' implies an unknown cause. Nevertheless, many abnormalities concomitant to AIS have been described, often with the suggestion ...

Last Updated: 13 May 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis; Posterior Spinal Fusion

 

Last Updated: 19 May 2016

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Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis

 

Last Updated: 10 Dec 2015

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Safety and Effectiveness Evaluation of the Minimal Invasive Deformity Correction (MID-C) System in Adolescent Idiopathic Scoliosis (AIS)
 

Status: Not yet recruiting

Condition Summary: Adolescent Idiopathic Scoliosis (AIS)

 

Last Updated: 13 Jan 2015

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