Ichthyosis vulgaris

Common Name(s)

Ichthyosis vulgaris

Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin.  It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid, salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ichthyosis vulgaris" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ichthyosis vulgaris" returned 16 free, full-text research articles on human participants. First 3 results:

Ichthyosis vulgaris and pycnodysostosis: an unusual occurrence.
 

Author(s): Vinayak Y Kshirsagar, Minhajuddin Ahmed, Suhel Nagarsenkar, Kulmani Sahoo, Kuldeep B Shah

Journal: Acta Med Acad. 2012 ;41(2):214-8.

 

Pycnodysostosis is a rare autosomal recessive disorder whose gene responsible for this phenotype (CTSK), mapped to human chromosome 1q21, code for the enzyme cathepsin K, a lysosomal cysteine protease; with an estimated incidence of 1.7 per 1 million births. This clinical entity includes ...

Last Updated: 21 Jan 2013

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Filaggrin genotype determines functional and molecular alterations in skin of patients with atopic dermatitis and ichthyosis vulgaris.
 

Author(s): Mårten C G Winge, Torborg Hoppe, Berit Berne, Anders Vahlquist, Magnus Nordenskjöld, Maria Bradley, Hans Törmä

Journal: PLoS ONE. 2011 ;6(12):e28254.

 

Several common genetic and environmental disease mechanisms are important for the pathophysiology behind atopic dermatitis (AD). Filaggrin (FLG) loss-of-function is of great significance for barrier impairment in AD and ichthyosis vulgaris (IV), which is commonly associated with AD. ...

Last Updated: 14 Dec 2011

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Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.
 

Author(s): Robert Gruber, Peter M Elias, Debra Crumrine, Tzu-Kai Lin, Johanna M Brandner, Jean-Pierre Hachem, Richard B Presland, Philip Fleckman, Andreas R Janecke, Aileen Sandilands, W H Irwin McLean, Peter O Fritsch, Michael Mildner, Erwin Tschachler, Matthias Schmuth

Journal: Am. J. Pathol.. 2011 May;178(5):2252-63.

 

Although it is widely accepted that filaggrin (FLG) deficiency contributes to an abnormal barrier function in ichthyosis vulgaris and atopic dermatitis, the pathomechanism of how FLG deficiency provokes a barrier abnormality in humans is unknown. We report here that the presence of ...

Last Updated: 25 Apr 2011

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Reviews from the PubMed Database

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The terms "Ichthyosis vulgaris" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Studies of Skin Microbes in Healthy People and in People With Skin Conditions
 

Status: Recruiting

Condition Summary: Atopic Dermatitis; Eczema; Ichthyosis Vulgaris

 

Last Updated: 11 Nov 2014

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