Ichthyosis

Common Name(s)

Ichthyosis

Ichthyosis is an umbrella term used to describe the many forms of inherited skin disorders in which dead skin cells accumulate in thick, dry scales on your skin's surface. Types of ichthyoses are classified by their appearance and their genetic cause. Ichthyosis vulgaris, accounts for 95% of all ichthyosis cases. Sometimes, mild cases of ichthyosis go undiagnosed because they're mistaken for extremely dry skin. Also, sometimes, other skin diseases, such as the allergic skin condition eczema, are associated with ichthyosis. Exposure to sunlight may improve or worsen the condition. In some cases, excess dead skin sheds much better from wet tanned skin after bathing or a swim, although the dry skin might be preferable to the damaging effects of sun exposure.

There is no cure for ichthyosis. The main goal of treatment is to moisturize and exfoliate. This helps prevent dryness, scaling, cracking and build-up of skin.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ichthyosis" for support, advocacy or research.

Foundation for Ichthyosis and Related Skin Types, Inc.

The Foundation's mission is to educate, inspire, and connect those touched by ichthyosis and related disorders through emotional support, information, advocacy and research funding for better treatments and eventual cures.

Last Updated: 15 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ichthyosis" for support, advocacy or research.

Foundation for Ichthyosis and Related Skin Types, Inc.

The Foundation's mission is to educate, inspire, and connect those touched by ichthyosis and related disorders through emotional support, information, advocacy and research funding for better treatments and eventual cures.

http://www.firstskinfoundation.org

Last Updated: 15 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ichthyosis" returned 309 free, full-text research articles on human participants. First 3 results:

Role of molecular testing in the multidisciplinary diagnostic approach of ichthyosis.
 

Author(s): Andrea Diociaiuti, May El Hachem, Elisa Pisaneschi, Simona Giancristoforo, Silvia Genovese, Pietro Sirleto, Renata Boldrini, Adriano Angioni

Journal:

 

The term ichthyosis describes a generalized disorder of cornification characterized by scaling and/or hyperkeratosis of different skin regions. Mutations in a broad group of genes related to keratinocyte differentiation and epidermal barrier function have been demonstrated to play ...

Last Updated: 14 Jan 2016

Go To URL
X-linked ichthyosis and Crigler-Najjar syndrome I: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3.
 

Author(s): Jinli Bai, Yujin Qu, Yanyan Cao, Yan Li, Wenhui Zhang, Yuwei Jin, Hong Wang, Fang Song

Journal: Mol Med Rep. 2016 Feb;13(2):1135-40.

 

X-linked ichthyosis (XLI) is an X-linked recessive skin disorder generally restricted to males, which arises from mutations in the steroid sulfatase (STS) gene located on Xp22.3. Crigler-Najjar syndrome (CN-I) is a rare autosomal recessive disease caused by the homozygous or compound ...

Last Updated: 10 Feb 2016

Go To URL
[Keratitis-Ichthyosis-Deafness syndrome (KID) in a Togolese child born from a consanguineous marriage].
 

Author(s): Koussak Kombaté, Bayaki Saka, Dadja Essoya Landoh, Abass Mouhari-Toure, Séfako Akakpo, Eric Belei, Wanguena Gnassingbé, Mohaman Awalou Djibril, Kissem Tchangaï-Walla, Palokinam Pitché

Journal:

 

Last Updated: 15 Dec 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ichthyosis" returned 17 free, full-text review articles on human participants. First 3 results:

Ichthyosis with confetti: clinics, molecular genetics and management.
 

Author(s): Liliana Guerra, Andrea Diociaiuti, May El Hachem, Daniele Castiglia, Giovanna Zambruno

Journal:

 

Ichthyosis with confetti (IWC) is an autosomal dominant congenital ichthyosis also known as ichthyosis variegata or congenital reticular ichthyosiform erythroderma. It manifests at birth with generalized ichthyosiform erythroderma or with a collodion baby picture. The erythrodermic ...

Last Updated: 19 Sep 2015

Go To URL
Annular epidermolytic ichthyosis: a rare phenotypic variant of bullous congenital ichthyosiform erythroderma.
 

Author(s): Aditi Jha, Jitender Taneja, V Ramesh, Avninder Singh

Journal: Indian J Dermatol Venereol Leprol. ;81(2):194-7.

 

Last Updated: 10 Mar 2015

Go To URL
Lamellar ichthyosis caused by a previously unreported homozygous ALOXE3 mutation in East Asia.
 

Author(s): Kazumitsu Sugiura, Masashi Akiyama

Journal: Acta Derm. Venereol.. 2015 Sep;95(7):858-9.

 

Last Updated: 6 Oct 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 1 Sep 2016

Go to URL
A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis
 

Status: Not yet recruiting

Condition Summary: Congenital Ichthyosis

 

Last Updated: 8 Aug 2016

Go to URL
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
 

Status: Recruiting

Condition Summary: Atopic Dermatitis; Eczema; Ichthyosis Vulgaris

 

Last Updated: 20 Oct 2016

Go to URL