Postural orthostatic tachycardia syndrome

Common Name(s)

Postural orthostatic tachycardia syndrome, Hypovolemic postural tachycardia syndrome

Postural orthostatic tachycardia syndrome (POTS) describes a group of symptoms that are commonly seen together. For people with POTS, going from a position of lying on their back (supine position) to sitting up causes an increased heart rate (tachycardia). The person’s blood pressure often does not change, but when it does it can be either lower or higher than normal. POTS may make it difficult for one to do day to day tasks and thus can affect quality of life.

People with POTS have a rapid heart rate when sitting up or standing. Other symptoms may include fainting, migraines, fatigue, and blotchy purplish skin while standing (blood pooling). Anyone can develop POTS, but it is more common in women under 50. Although the symptoms are similar to those of panic and anxiety disorders, POTS is not a mental health condition. Its underlying causes are many, including certain genetic conditions (e.g. Ehlers-Danlos syndrome, mitochondrial disease), diabetes, hepatitis C, pregnancy, multiple sclerosis, vitamin deficiencies, anemia, certain infections (e.g. mononucleosis, Epstein Barr virus, & Lyme disease), autoimmune disorders (e.g. Lupus, Sjorgren’s syndrome, & sarcoidosis) and more.

A tilt table test, which monitors heart rate as the table goes from a flat to upright position, is used to diagnose POTS. Other tests will be performed to determine the underlying cause. Treatment may include certain dietary changes and medications, but again is dependent on the underlying cause. Long term outlook is also dependent on the underlying cause and the severity of symptoms. Research is ongoing, so talk to your doctor about the most current treatment options. If your diagnosis includes a genetic condition, talk to a genetic counselor to learn more information about genetic testing and the condition. Support groups are also good resources of information and can help connect you with others living with POTS.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Postural orthostatic tachycardia syndrome" for support, advocacy or research.

Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

Last Updated: 17 Aug 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Postural orthostatic tachycardia syndrome" for support, advocacy or research.

Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

http://www.ehlers-danlos.org

Last Updated: 17 Aug 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Postural orthostatic tachycardia syndrome" returned 46 free, full-text research articles on human participants. First 3 results:

[Time-dependent heart rate variability in the head-up tilt test in children with postural orthostatic tachycardia syndrome].
 

Author(s): Jing Ran, Cheng Wang, Run-Mei Zou, Li-Jia Wu, Ping Lin, Fang Li, Yi Xu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 Oct;17(10):1070-3.

 

To study the time-dependent heart rate (HR) variability in the head-up tilt test (HUTT) in children with postural orthostatic tachycardia syndrome (POTS) and to explore the HR diagnostic criteria for POTS in children.

Last Updated: 20 Oct 2015

Go To URL
Disturbances of gastrointestinal transit and autonomic functions in postural orthostatic tachycardia syndrome.
 

Author(s): A Loavenbruck, J Iturrino, W Singer, D M Sletten, P A Low, A R Zinsmeister, A E Bharucha

Journal: Neurogastroenterol. Motil.. 2015 Jan;27(1):92-8.

 

Gastrointestinal symptoms are common in the postural orthostatic tachycardia syndrome (POTS). However, few studies have evaluated gastrointestinal transit in POTS. Our primary objectives were to evaluate gastrointestinal emptying and the relationship with autonomic dysfunctions in POTS.

Last Updated: 5 Jan 2015

Go To URL
[Pyridostigmine in the treatment of postural orthostatic tachycardia syndrome].
 

Author(s): Ilknur Can, Venkatakrishna Tholakanahalli

Journal: Turk Kardiyol Dern Ars. 2014 Sep;42(6):553-5.

 

A 34-year-old female patient was admitted with the complaints of inability to stand upright, palpitations, dizziness, and fatigue in the upright posture for the last one year. She was found to stand upright for less than one minute without symptoms. Tilt table testing showed that, ...

Last Updated: 3 Nov 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Postural orthostatic tachycardia syndrome" returned 3 free, full-text review articles on human participants. First 3 results:

A review of postural orthostatic tachycardia syndrome.
 

Author(s): Sheila Carew, Margaret O Connor, John Cooke, Richard Conway, Christine Sheehy, Aine Costelloe, Declan Lyons

Journal: Europace. 2009 Jan;11(1):18-25.

 

A 21-year-old female reports an 18-month history of light-headedness on standing. This is often associated with palpitations and a feeling of intense anxiety. She has had two black-outs in the past 12 months. She is not taking any regular medications. Her supine blood pressure was ...

Last Updated: 17 Dec 2008

Go To URL
Postural orthostatic tachycardia syndrome.
 

Author(s): A K Agarwal, R Garg, A Ritch, P Sarkar

Journal: Postgrad Med J. 2007 Jul;83(981):478-80.

 

Postural orthostatic tachycardia syndrome (POTS) is an autonomic disturbance which has become better understood in recent years. It is now thought to encompass a group of disorders that have similar clinical features, such as orthostatic intolerance, but individual distinguishing ...

Last Updated: 10 Jul 2007

Go To URL
Chronic orthostatic intolerance and the postural tachycardia syndrome (POTS).
 

Author(s): Julian M Stewart

Journal: J. Pediatr.. 2004 Dec;145(6):725-30.

 

Last Updated: 6 Dec 2004

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
 

Status: Recruiting

Condition Summary: Postural Tachycardia Syndrome; Postural Orthostatic Tachycardia Syndrome

 

Last Updated: 7 Dec 2015

Go to URL
Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
 

Status: Recruiting

Condition Summary: Postural Orthostatic Tachycardia Syndrome

 

Last Updated: 2 Jun 2015

Go to URL
Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
 

Status: Recruiting

Condition Summary: Postural Orthostatic Tachycardia Syndrome

 

Last Updated: 13 Jan 2016

Go to URL