Hypothalamic dysfunction

Common Name(s)

Hypothalamic dysfunction

Hypothalamic dysfunction refers to a condition in which the hypothalamus is not working properly. The hypothalamus produces hormones that control body temperature, hunger, moods, release of hormones from many glands such as the pituitary gland, sex drive, sleep, and thirst. The signs and symptoms patients have vary depending on the hormones missing. A number of different causes including anorexia, bleeding, genetic disorder, tumors, and more have been linked to hypothalamic dysfunction. Treatment depends on the cause of the hypothalamic dysfunction.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypothalamic dysfunction" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypothalamic dysfunction" returned 21 free, full-text research articles on human participants. First 3 results:

Hypothalamic-pituitary-adrenal axis dysfunction in non-clinical psychosis.
 

Author(s): Vijay Anand Mittal, Joseph Michael Orr, Andrea Pelletier, Derek James Dean, Ashley Smith, Jessica Lunsford-Avery

Journal: Psychiatry Res. 2013 Apr;206(2-3):315-7.

 

While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest ...

Last Updated: 1 Apr 2013

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A case of rapid-onset obesity with hypothalamic dysfunction, hypoventilation, autonomic dysregulation, and neural crest tumor: ROHHADNET syndrome.
 

Author(s): Ayhan Abaci, Gonul Catli, Erhan Bayram, Tolga Koroglu, Hatice Nur Olgun, Kamer Mutafoglu, Ayse Semra Hiz, Handan Cakmakci, Ece Bober

Journal: Endocr Pract. ;19(1):e12-6.

 

Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare disorder that mimics both common obesity and genetic obesity syndromes along with several endocrine disorders during early childhood. We aim to present the clinical features, ...

Last Updated: 25 Feb 2013

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Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects.
 

Author(s): Simone van de Sande-Lee, Fabrício R S Pereira, Dennys E Cintra, Paula T Fernandes, Adilson R Cardoso, Célia R Garlipp, Eliton A Chaim, Jose C Pareja, Bruno Geloneze, Li Min Li, Fernando Cendes, Licio A Velloso

Journal: Diabetes. 2011 Jun;60(6):1699-704.

 

Inflammation and dysfunction of the hypothalamus are common features of experimental obesity. However, it is unknown whether obesity and massive loss of body mass can modify the immunologic status or the functional activity of the human brain. Therefore, the aim of this study was ...

Last Updated: 27 May 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypothalamic dysfunction" returned 5 free, full-text review articles on human participants. First 3 results:

[Hypothalamic dysfunction in obesity].
 

Author(s): Simone van de Sande-Lee, Licio A Velloso

Journal: Arq Bras Endocrinol Metabol. 2012 Aug;56(6):341-50.

 

Obesity, defined as abnormal or excessive fat accumulation that may impair life quality, is one of the major public health problems worldwide. It results from an imbalance between food intake and energy expenditure. The control of energy balance in animals and humans is performed ...

Last Updated: 19 Sep 2012

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Rapid-onset obesity with hypothalamic dysfunction, hypoventilation and autonomic dysregulation (ROHHAD): a case with additional features and review of the literature.
 

Author(s): H B Chew, L H Ngu, W T Keng

Journal:

 

A rare syndrome of rapid-onset obesity with hypothalamic dysfunction, hypoventilation and autonomic dysregulation (ROHHAD) has been recently described. We report the first patient with this syndrome in Southeast Asia and review reported cases to date. Our patient was good health with ...

Last Updated: 20 Jun 2012

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[Childhood maltreatment and adult psychopathology: pathways to hypothalamic-pituitary-adrenal axis dysfunction].
 

Author(s): Marcelo F Mello, Alvaro A Faria, Andrea F Mello, Linda L Carpenter, Audrey R Tyrka, Lawrence H Price

Journal: Rev Bras Psiquiatr. 2009 Oct;31 Suppl 2():S41-8.

 

The aim of this paper was to examine the relationship between childhood maltreatment and adult psychopathology, as reflected in hypothalamic-pituitary-adrenal axis dysfunction.

Last Updated: 7 Dec 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Reproductive Hormones During Sustained Administration of Kisspeptin
 

Status: Not yet recruiting

Condition Summary: Fertility Disorders; Hypothalamic Dysfunction

 

Last Updated: 5 Mar 2014

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Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women
 

Status: Recruiting

Condition Summary: Anovulation; Oligo-ovulation; Hypothalamic-pituitary Dysfunction; Polycystic Ovarian Syndrome

 

Last Updated: 4 Jun 2014

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Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors
 

Status: Recruiting

Condition Summary: Hypopituitarism; Hypogonadism; Thyroid Dysfunction; Bone Diseases, Metabolic

 

Last Updated: 14 Mar 2014

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