Hypospadias

Common Name(s)

Hypospadias

Hypospadias is a birth defect in which the urethra (the tube that drains urine from the bladder) is abnormally located on the underside of the penis instead of at the tip. It is typically diagnosed at birth, but less severe hypospadius can potentially go overlooked. Hypospadias is caused by an inbalance of hormones required for normal development of the urethra. Treatment involves surgery to reposition the urethra, most commonly resulting in normal appearance and function of the penis.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypospadias" for support, advocacy or research.

AIS-DSD Support Group

The AIS-DSD Support Group is a compassionate community of individuals, families and allies collaborating to promote better lives and informed decision-making through advancement of knowledge so no one will face a diagnosis alone.

Last Updated: 12 Jan 2015

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Hypospadias Epispadias Association

The Hypospadias and Epispadias Association, Inc. (HEA) is an organization founded in the year 2000 for the support and education of people born with hypospadias or epispadias and their families, loved ones, and medical care givers.

Last Updated: 25 Mar 2013

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Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

Last Updated: 8 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypospadias" for support, advocacy or research.

AIS-DSD Support Group

The AIS-DSD Support Group is a compassionate community of individuals, families and allies collaborating to promote better lives and informed decision-making through advancement of knowledge so no one will face a diagnosis alone.

http://www.aisdsd.org

Last Updated: 12 Jan 2015

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Hypospadias Epispadias Association

The Hypospadias and Epispadias Association, Inc. (HEA) is an organization founded in the year 2000 for the support and education of people born with hypospadias or epispadias and their families, loved ones, and medical care givers.

http://www.HEAinfo.org

Last Updated: 25 Mar 2013

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Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

http://www.PullthruNetwork.org

Last Updated: 8 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypospadias" returned 155 free, full-text research articles on human participants. First 3 results:

2-octyl cyanoacrylate versus reintervention for closure of urethrocutaneous fistulae after urethroplasty for hypospadias: a randomized controlled trial.
 

Author(s): Gabriela Ambriz-González, Pedro Aguirre-Ramirez, José Manuel García-de León, Francisco Javier León-Frutos, Sergio Adrián Montero-Cruz, Xóchitl Trujillo, Clotilde Fuentes-Orozco, Michel Dassaejv Macías-Amezcua, Andrea del Socorro Álvarez-Villaseñor, Ana Olivia Cortés-Flores, Mariana Chávez-Tostado, Alejandro González-Ojeda

Journal:

 

Urethrocutaneous fistulae (UCFs) represent one of the most frequent causes of morbidity after urethroplasty. Hypospadias can be repaired using different surgical techniques, but-regardless of technique-the incidence of UCF ranges between 10% and 40%. Surgical repair of UCF remains ...

Last Updated: 26 Nov 2014

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Our experience in chordee without hypospadias: results of 102 cases.
 

Author(s): Emre Can Polat, Mehmet Remzi Erdem, Ramazan Topaktas, Cevper Ersoz, Sinasi Yavuz Onol

Journal:

 

We present long-term surgical experience of 102 chordee without hypospadias cases.

Last Updated: 7 Sep 2014

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Risk factors for hypospadias in China.
 

Author(s): Ling-Fan Xu, Chao-Zhao Liang, Julia Lipianskaya, Xian-Guo Chen, Song Fan, Li Zhang, Jun Zhou, Sheng Tai, Chang-Qin Jiang

Journal: Asian J. Androl.. ;16(5):778-81.

 

This case-controlled study was designed to evaluate the association between various baseline parental factors and the risk of hypospadias in China. Patients were selected from tertiary referral hospitals in Anhui, a province in mid-eastern China. A questionnaire was given to the parents ...

Last Updated: 28 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypospadias" returned 17 free, full-text review articles on human participants. First 3 results:

Tubularized incised plate urethroplasty for hypospadias reoperation: a review and meta-analysis.
 

Author(s): Seyed A Mousavi, Mohsen Aarabi

Journal: Int Braz J Urol. ;40(5):588-95.

 

Tubularized Incised Plate (TIP) urethroplasty is a technique for urethral reconstruction of hypospadias although there are some controversies for its use in recurrent cases. The aim of this study was to review the results of TIP technique in various studies and the usage of different ...

Last Updated: 16 Dec 2014

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Comparison of transverse island flap onlay and tubularized incised-plate urethroplasties for primary proximal hypospadias: a systematic review and meta-analysis.
 

Author(s): Dongdong Xiao, Xin Nie, Wenyue Wang, Juan Zhou, Ming Zhang, Zhe Zhou, Yang Zhao, Meng Gu, Zhong Wang, Mujun Lu

Journal:

 

This meta-analysis was conducted to compare postoperative outcomes between transverse island flap (TVIF) onlay and tubularized incised-plate (TIP) urethroplasties for primary proximal hypospadias.

Last Updated: 9 Sep 2014

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Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidence.
 

Author(s): Suzan L Carmichael, Gary M Shaw, Edward J Lammer

Journal: Birth Defects Res. Part A Clin. Mol. Teratol.. 2012 Jul;94(7):499-510.

 

This review evaluates current knowledge related to trends in the prevalence of hypospadias, the association of hypospadias with endocrine-disrupting exposures, and the potential contribution of genetic susceptibility to its etiology. The review focuses on epidemiologic evidence. Increasing ...

Last Updated: 10 Jul 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prophylactic Antibiotics or Placebo After Hypospadias Repair
 

Status: Recruiting

Condition Summary: Hypospadias

 

Last Updated: 27 Oct 2014

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Hemostasis During Hypospadias Surgery
 

Status: Recruiting

Condition Summary: Hypospadias Repair

 

Last Updated: 15 Oct 2014

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Last Updated: 3 Feb 2015

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