Hypopituitarism

Common Name(s)

Hypopituitarism

Hypopituitarism occurs when the body has low levels of certain hormones made by the pituitary gland.  The pituitary gland normally makes several hormones (including growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, prolactin, follicle stimulating hormone and luteinizing hormone, vasopressin, and oxytocin).  These hormones are important for directing body growth and development, and for regulating blood pressure and metabolism.  Symptoms of this condition vary and depend on which hormones are affected.  Treatment depends on the cause of this condition; once the cause is corrected, medication (hormone replacement therapy) must be taken to provide the body with the normal amount of hormones.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypopituitarism" for support, advocacy or research.

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Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypopituitarism" for support, advocacy or research.

Logo
Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

http://www.pituitary.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypopituitarism" returned 167 free, full-text research articles on human participants. First 3 results:

Fatal Candida septic shock during systemic chemotherapy in lung cancer patient receiving corticosteroid replacement therapy for hypopituitarism: a case report.
 

Author(s): Daisuke Morichika, Akiko Sato-Hisamoto, Katsuyuki Hotta, Katsuyoshi Takata, Noriko Iwaki, Koji Uchida, Daisuke Minami, Toshio Kubo, Mitsune Tanimoto, Katsuyuki Kiura

Journal: Jpn. J. Clin. Oncol.. 2014 May;44(5):501-5.

 

Invasive candidiasis has increased as nosocomial infection recently in cancer patients who receive systemic chemotherapy, and the timely risk assessment for developing such specific infection is crucial. Especially in those concomitantly with hypopituitarism, febrile neutropenia with ...

Last Updated: 30 Apr 2014

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[Pseudo-pituitary tumor and hypopituitarism secondary to a sphenoid sinus inverted papilloma].
 

Author(s): Karina Danilowicz, Oscar D Bruno, Marcos Manavela, Javier Herrera, Eugenia Salvai

Journal: Medicina (B Aires). 2013 ;73(5):467-9.

 

Inverted papilloma (IP) is a benign uncommon epithelial tumor, arising mostly from the lateral nasal wall. Though benign, this lesion is highly invasive into surrounding tissues and malignant transformation may occur. Primary IP of the sphenoid sinus and intracranial extension with ...

Last Updated: 24 Oct 2013

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Acute hypophysitis and hypopituitarism in early syphilitic meningitis in a HIV-infected patient: a case report.
 

Author(s): Christoph D Spinner, Sebastian Noe, Christiane Schwerdtfeger, Antonia Todorova, Jochen Gaa, Roland M Schmid, Dirk H Busch, Michael Neuenhahn

Journal:

 

Sexually transmitted diseases and most notably syphilis-infections are rising amongst men who have sex with men. In HIV-co-infected patients, an accelerated clinical course of syphilis neurological involvement is known.

Last Updated: 17 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypopituitarism" returned 20 free, full-text review articles on human participants. First 3 results:

GH therapy and cancer risk in hypopituitarism: what we know from human studies.
 

Author(s): Sandra Pekic, Vera Popovic

Journal:

 

It has been difficult to identify factors that affect the risk of cancer, but we know that people are at higher risk as they get older, or if they have a strong family history of cancer. The potential influence of environmental and behavioral factors remains poorly understood. Early ...

Last Updated: 2 Oct 2013

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Pituitary stem cell update and potential implications for treating hypopituitarism.
 

Author(s): Frederic Castinetti, Shannon W Davis, Thierry Brue, Sally A Camper

Journal: Endocr. Rev.. 2011 Aug;32(4):453-71.

 

Stem cells have been identified in organs with both low and high cell turnover rates. They are characterized by the expression of key marker genes for undifferentiated cells, the ability to self-renew, and the ability to regenerate tissue after cell loss. Several recent reports present ...

Last Updated: 8 Aug 2011

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Hypopituitarism following envenoming by Russell's vipers (Daboia siamensis and D. russelii) resembling Sheehan's syndrome: first case report from Sri Lanka, a review of the literature and recommendations for endocrine management.
 

Author(s): C N Antonypillai, J A H Wass, D A Warrell, H N Rajaratnam

Journal: QJM. 2011 Feb;104(2):97-108.

 

Russell's vipers (Daboia russelii and D. siamensis) inhabit 10 South and South East Asian countries. People envenomed by these snakes suffer coagulopathy, bleeding, shock, neurotoxicity, acute kidney injury and local tissue damage leading to severe morbidity and mortality. An unusual ...

Last Updated: 19 Jan 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Androgen Replacement Therapy in Women With Hypopituitarism
 

Status: Recruiting

Condition Summary: Hypopituitarism

 

Last Updated: 23 Jun 2005

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Hormone Deficiency After Brain Injury During Combat
 

Status: Not yet recruiting

Condition Summary: Traumatic Brain Injury; Hypopituitarism

 

Last Updated: 14 Aug 2012

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