Hypoparathyroidism

Common Name(s)

Hypoparathyroidism

Hypoparathyroidism is is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

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Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

Last Updated: 1 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

Logo
Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

http://www.hpth.org.uk

Last Updated: 1 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoparathyroidism" returned 285 free, full-text research articles on human participants. First 3 results:

Epileptic seizure, as the first symptom of hypoparathyroidism in children, does not require antiepileptic drugs.
 

Author(s): Meng-Jia Liu, Jiu-Wei Li, Xiu-Yu Shi, Lin-Yan Hu, Li-Ping Zou

Journal: Childs Nerv Syst. 2017 Feb;33(2):297-305.

 

Patients with hypoparathyroidism exhibit metabolic disorders (hypocalcemia) and brain structural abnormalities (brain calcifications). Currently, studies have determined whether antiepileptic drug (AED) treatment is required for epileptic seizures in children with hypoparathyroidism.

Last Updated: 13 Dec 2016

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Living-donor parathyroid allotransplantation for therapy-refractory postsurgical persistent hypoparathyroidism in a nontransplant recipient - three year results: a case report.
 

Author(s): Ayman Agha, Marcus Nils Scherer, Christian Moser, Thomas Karrasch, Christiane Girlich, Fabian Eder, Ernst-Michael Jung, Hans Juergen Schlitt, Andreas Schaeffler

Journal:

 

Therapy-refractory persistent hypoparathyroidism after extensive neck surgery is a rare but severe complication. Parathyroid allotransplantation may represent a definitive treatment option.

Last Updated: 4 Aug 2016

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Treatment of severe life threatening hypocalcemia with recombinant human teriparatide in patients with postoperative hypoparathyroidism - a case series.
 

Author(s): Elżbieta Andrysiak-Mamos, Ewa Żochowska, Agnieszka Kaźmierczyk-Puchalska, Michał Popow, Dorota Kaczmarska-Turek, Janusz Pachucki, Tomasz Bednarczuk, Anhelli Syrenicz

Journal: Endokrynol Pol. 2016 ;67(4):403-12.

 

Hypocalcaemia is a common postoperative complication, both after the resection of parathyroid adenoma associated with primary hyperparathyroidism and after total thyroidectomy due to thyroid cancer or nodular goitre. For a few years, in patients with postoperative hypoparathyroidism ...

Last Updated: 2 Sep 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoparathyroidism" returned 14 free, full-text review articles on human participants. First 3 results:

Bone disease in hypoparathyroidism.
 

Author(s): Bart L Clarke

Journal: Arq Bras Endocrinol Metabol. 2014 Jul;58(5):545-52.

 

Hypoparathyroidism is a rare disorder that may be acquired or inherited. Postsurgical hypoparathyroidism is responsible for the majority of acquired hypoparathyroidism. Bone disease occurs in hypoparathyroidism due to markedly reduced bone remodeling due to the absence or low levels ...

Last Updated: 29 Aug 2014

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Use of parathyroid hormone in hypoparathyroidism.
 

Author(s): N E Cusano, M R Rubin, D Irani, J Sliney, J P Bilezikian

Journal: J. Endocrinol. Invest.. 2013 Dec;36(11):1121-7.

 

Hypoparathyroidism is a disorder characterized by hypocalcemia, deficient PTH, and abnormal bone remodeling. Standard treatment of hypoparathyroidism consists of oral calcium and vitamin D supplementation. However, maintaining serum calcium levels can be a challenge. In addition, ...

Last Updated: 21 Jan 2014

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Pure red cell aplasia as a presenting feature in systemic lupus erythematosus and association with thymoma, hypothyroidism and hypoparathyroidism: a case report and literature review.
 

Author(s): Sasan Fallahi, Mahmoud Akbarian, Shahriar Dabiri

Journal: Iran J Allergy Asthma Immunol. 2014 Apr;13(2):138-43.

 

This paper presents a 54-year-old female with lupus whom severe anaemia due to pure red cell aplasia (PRCA) was the first manifestation. There was seven years interval between PRCA onset and diagnosis of lupus. Thymectomy due to thymoma had been carried out six years before but anaemia ...

Last Updated: 16 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Survey on Epidemiology of Hypoparathyroidism in France
 

Status: Recruiting

Condition Summary: Hypoparathyroidism

 

Last Updated: 17 Jul 2016

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Steroids in the Postoperative Transient Hypoparathyroidism Total Thyroidectomy
 

Status: Recruiting

Condition Summary: Transient Hypoparathyroidism

 

Last Updated: 4 Apr 2016

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PARADIGHM A Natural History Registry for Patients With Chronic Hypoparathyroidism
 

Status: Recruiting

Condition Summary: Chronic Hypoparathyroidism

 

Last Updated: 3 Apr 2017

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