Hypoparathyroidism

Common Name(s)

Hypoparathyroidism

Hypoparathyroidism is is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

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Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

Last Updated: 1 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

Logo
Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

http://www.hpth.org.uk

Last Updated: 1 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoparathyroidism" returned 290 free, full-text research articles on human participants. First 3 results:

Living-donor parathyroid allotransplantation for therapy-refractory postsurgical persistent hypoparathyroidism in a nontransplant recipient - three year results: a case report.
 

Author(s): Ayman Agha, Marcus Nils Scherer, Christian Moser, Thomas Karrasch, Christiane Girlich, Fabian Eder, Ernst-Michael Jung, Hans Juergen Schlitt, Andreas Schaeffler

Journal:

 

Therapy-refractory persistent hypoparathyroidism after extensive neck surgery is a rare but severe complication. Parathyroid allotransplantation may represent a definitive treatment option.

Last Updated: 4 Aug 2016

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[Reduction in requirements of oral calcium and 1-25 dihydroxy vitamin D in patients with post-surgical hypoparathyroidism treated with teriparatide (PTH1-34)].
 

Author(s): Leticia Eugenia Gutiérrez-Cerecedo, Alma Vergara-López, José Vicente Rosas-Barrientos, Miguel Ángel Guillén-González

Journal: Gac Med Mex. ;152(3):322-8.

 

The objective of the study is to evaluate the effect of daily administration of recombinant parathyroid hormone (PTH1-34), 20 μg, on serum calcium concentrations (Cas), and the requirements of oral calcium and calcitriol in patients with hypoparathyroidism. It is a prospective, longitudinal ...

Last Updated: 23 Jun 2016

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Chronic Hypoparathyroidism Due to Partial Thyroidectomy with Intracranial Calcification.
 

Author(s): Indra Wijaya

Journal: Acta Med Indones. 2016 Jan;48(1):68-9.

 

A 57 year old female came with the complaint of recurrent headache, often fatigue, and sometimes feel numbs and rigid in her extremities, no other symptom was noted. Her body weight is stable and she was in menopausal state. She had a history of partial thyroidectomy 20 years ago ...

Last Updated: 31 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoparathyroidism" returned 15 free, full-text review articles on human participants. First 3 results:

Bone disease in hypoparathyroidism.
 

Author(s): Bart L Clarke

Journal: Arq Bras Endocrinol Metabol. 2014 Jul;58(5):545-52.

 

Hypoparathyroidism is a rare disorder that may be acquired or inherited. Postsurgical hypoparathyroidism is responsible for the majority of acquired hypoparathyroidism. Bone disease occurs in hypoparathyroidism due to markedly reduced bone remodeling due to the absence or low levels ...

Last Updated: 29 Aug 2014

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Use of parathyroid hormone in hypoparathyroidism.
 

Author(s): N E Cusano, M R Rubin, D Irani, J Sliney, J P Bilezikian

Journal: J. Endocrinol. Invest.. 2013 Dec;36(11):1121-7.

 

Hypoparathyroidism is a disorder characterized by hypocalcemia, deficient PTH, and abnormal bone remodeling. Standard treatment of hypoparathyroidism consists of oral calcium and vitamin D supplementation. However, maintaining serum calcium levels can be a challenge. In addition, ...

Last Updated: 21 Jan 2014

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Pure red cell aplasia as a presenting feature in systemic lupus erythematosus and association with thymoma, hypothyroidism and hypoparathyroidism: a case report and literature review.
 

Author(s): Sasan Fallahi, Mahmoud Akbarian, Shahriar Dabiri

Journal: Iran J Allergy Asthma Immunol. 2014 Apr;13(2):138-43.

 

This paper presents a 54-year-old female with lupus whom severe anaemia due to pure red cell aplasia (PRCA) was the first manifestation. There was seven years interval between PRCA onset and diagnosis of lupus. Thymectomy due to thymoma had been carried out six years before but anaemia ...

Last Updated: 16 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Survey on Epidemiology of Hypoparathyroidism in France
 

Status: Recruiting

Condition Summary: Hypoparathyroidism

 

Last Updated: 17 Jul 2016

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Steroids in the Postoperative Transient Hypoparathyroidism Total Thyroidectomy
 

Status: Recruiting

Condition Summary: Transient Hypoparathyroidism

 

Last Updated: 4 Apr 2016

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PARADIGHM A Natural History Registry for Patients With Chronic Hypoparathyroidism
 

Status: Recruiting

Condition Summary: Chronic Hypoparathyroidism

 

Last Updated: 13 Jan 2017

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