Hypertrophic Cardiomyopathy

Common Name(s)

Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a disease in which the walls of the heart muscle become abnormally thick. When the walls of the heart are thick it makes it difficult to pump blood. HCM can affect men and women of any age. HCM often goes undiagnosed because people often have few symptoms. Some may experience symptoms such as shortness of breath, chest pain, fainting, dizziness, fatigue, heart murmur or sensation of a racing heart beat. A physician can typically diagnose HCM using a heart function test called an echocardiogram. Additional tests, such as a treadmill stress test, may be needed. Medication and certain medical procedures can help manage symptoms and prevent sudden cardiac death. People with HCM often lead normal lives with no significant problems.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypertrophic Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

Last Updated: 12 Apr 2014

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

Last Updated: 20 May 2014

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Hypertrophic Cardiomyopathy Association

Our mission is to provide support, advocacy and education to patients, and their family members, the medical community and the public about Hypertrophic Cardiomyopathy.

Last Updated: 6 May 2013

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Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 30 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypertrophic Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

http://www.barthsyndrome.org

Last Updated: 12 Apr 2014

View Details
Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

http://www.childrenscardiomyopathy.org

Last Updated: 20 May 2014

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Hypertrophic Cardiomyopathy Association

Our mission is to provide support, advocacy and education to patients, and their family members, the medical community and the public about Hypertrophic Cardiomyopathy.

http://www.4hcm.org

Last Updated: 6 May 2013

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Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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General Support Organizations

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General Resources

2012 Conference Program

Barth Syndrome Foundation 2012 Conference Program

Updated 2 Nov 2012

Open Doc
Barth Syndrome Professional Healthcare Brochure

Important information regarding diagnosis and treatment of Barth syndrome.

Updated 12 Apr 2014

Open Doc
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypertrophic Cardiomyopathy" returned 1684 free, full-text research articles on human participants. First 3 results:

Robot-assisted septal myectomy for hypertrophic cardiomyopathy with left ventricular outflow tract obstruction.
 

Author(s): Zain Khalpey, Lev Korovin, W Randolph Chitwood, Robert Poston

Journal: J. Thorac. Cardiovasc. Surg.. 2014 May;147(5):1708-9.

 

Last Updated: 5 May 2014

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Heart rate recovery in patients with hypertrophic cardiomyopathy.
 

Author(s): Vimal Patel, Christopher H Critoph, Malcolm C Finlay, Bryan Mist, Pier D Lambiase, Perry M Elliott

Journal: Am. J. Cardiol.. 2014 Mar;113(6):1011-7.

 

Recovery in heart rate (HR) after exercise is a measure of autonomic function and a prognostic indicator in cardiovascular disease. The aim of this study was to characterize heart rate recovery (HRR) and to determine its relation to cardiac function and morphology in patients with ...

Last Updated: 3 Mar 2014

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A lethal course of hypertrophic cardiomyopathy in Noonan syndrome due to a novel germline mutation in the KRAS gene: case study.
 

Author(s): Gregor Nosan, Sara Bertok, Samo Vesel, Helger G Yntema, Darja Paro-Panjan

Journal: Croat. Med. J.. 2013 Dec;54(6):574-8.

 

Noonan syndrome is a relatively common and heterogeneous genetic disorder, including congenital heart defect in more than half of the cases. If the defect is not large, life expectancy is normal. Here we report on a case of an infant with Noonan syndrome and rapidly progressive hypertrophic ...

Last Updated: 2 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypertrophic Cardiomyopathy" returned 138 free, full-text review articles on human participants. First 3 results:

The influence of Angiotensin converting enzyme and angiotensinogen gene polymorphisms on hypertrophic cardiomyopathy.
 

Author(s): Rong Luo, Xiaoping Li, Yuequn Wang, Yongqing Li, Yun Deng, Yongqi Wan, Zhigang Jiang, Wei Hua, Xiushan Wu

Journal:

 

Some studies have reported that angiotensin converting enzyme (ACE) and angiotensinogen (AGT) genes have been associated with hypertrophic cardiomyopathy (HCM). However, there have been inconsonant results among different studies. To clarify the influence of ACE and AGT on HCM, a ...

Last Updated: 8 Nov 2013

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Progress in the molecular genetics of hypertrophic cardiomyopathy: a mini-review.
 

Author(s): Tao Tian, Yaxin Liu, Xianliang Zhou, Lei Song

Journal: Gerontology. 2013 ;59(3):199-205.

 

Hypertrophic cardiomyopathy (HCM), which is characterized by unexplained and asymmetric left ventricular hypertrophy in the absence of other cardiac or systemic diseases, is an inherited cardiovascular disease and presents rising penetrance with aging.

Last Updated: 8 May 2013

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Hypertrophic cardiomyopathy: diagnosis, risk stratification and treatment.
 

Author(s): Daniel L Jacoby, Eugene C DePasquale, William J McKenna

Journal: CMAJ. 2013 Feb;185(2):127-34.

 

Last Updated: 5 Feb 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Continous Positive Airway Pressure (CPAP) in Hypertrophic Cardiomyopathy
 

Status: Recruiting

Condition Summary: Non-obstructive Hypertrophic Cardiomyopathy; Obstructive Hypertrophic Cardiomyopathy

 

Last Updated: 27 Jun 2012

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HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy
 

Status: Recruiting

Condition Summary: Hypertrophic Cardiomyopathy

 

Last Updated: 8 Apr 2014

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Comparison of Data Obtained by Echocardiography and Magnetic Resonance Imaging in Hypertrophic Cardiomyopathy
 

Status: Recruiting

Condition Summary: Hypertrophic Cardiomyopathy

 

Last Updated: 17 Apr 2006

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