Hyperoxaluria

Common Name(s)

Hyperoxaluria

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hyperoxaluria" for support, advocacy or research.

Oxalosis & Hyperoxaluria Foundation

To seek the cause, improve the clinical treatment and discover the cure of hyperoxaluria and oxalate stone disease and enhance the quality of life of patients and their families.

Last Updated: 19 Mar 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hyperoxaluria" for support, advocacy or research.

Oxalosis & Hyperoxaluria Foundation

To seek the cause, improve the clinical treatment and discover the cure of hyperoxaluria and oxalate stone disease and enhance the quality of life of patients and their families.

http://www.ohf.org/

Last Updated: 19 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hyperoxaluria" returned 144 free, full-text research articles on human participants. First 3 results:

Dietary hyperoxaluria is not reduced by treatment with lactic acid bacteria.
 

Author(s): Roswitha Siener, Diana J Bade, Albrecht Hesse, Bernd Hoppe

Journal:

 

Secondary hyperoxaluria either based on increased intestinal absorption of oxalate (enteric), or high oxalate intake (dietary), is a major risk factor of calcium oxalate urolithiasis. Oxalate-degrading bacteria might have beneficial effects on urinary oxalate excretion resulting from ...

Last Updated: 19 Dec 2013

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Primary hyperoxaluria.
 

Author(s): Gill Rumsby, Pierre Cochat

Journal: N. Engl. J. Med.. 2013 Nov;369(22):2163.

 

Last Updated: 28 Nov 2013

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The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I.
 

Author(s): Noel Mesa-Torres, Israel Fabelo-Rosa, Debora Riverol, Cristina Yunta, Armando Albert, Eduardo Salido, Angel L Pey

Journal:

 

Primary hyperoxaluria type I (PH1) is a conformational disease which result in the loss of alanine:glyoxylate aminotransferase (AGT) function. The study of AGT has important implications for protein folding and trafficking because PH1 mutants may cause protein aggregation and mitochondrial ...

Last Updated: 8 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hyperoxaluria" returned 14 free, full-text review articles on human participants. First 3 results:

Combined liver and kidney transplantation in primary hyperoxaluria: a report of three cases and review of the literature.
 

Author(s): Prasad Nair, Torki Al-Otaibi, Narayanan Nampoory, Wafa'a Al-Qabandi, Tarek Said, Medhat Abdul Halim, Osama Gheith

Journal: Saudi J Kidney Dis Transpl. 2013 Sep;24(5):969-75.

 

Primary hyperoxaluria type-1 (PH-1) is a rare autosomal recessive metabolic disorder leading to excessive oxalate production, deposition of calcium oxalate crystals in the kidney, nephrocalcinosis, progressive renal failure and systemic deposition of oxalate (oxalosis). Combined liver ...

Last Updated: 13 Sep 2013

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Protein homeostasis defects of alanine-glyoxylate aminotransferase: new therapeutic strategies in primary hyperoxaluria type I.
 

Author(s): Angel L Pey, Armando Albert, Eduardo Salido

Journal: Biomed Res Int. 2013 ;2013():687658.

 

Alanine-glyoxylate aminotransferase catalyzes the transamination between L-alanine and glyoxylate to produce pyruvate and glycine using pyridoxal 5'-phosphate (PLP) as cofactor. Human alanine-glyoxylate aminotransferase is a peroxisomal enzyme expressed in the hepatocytes, the main ...

Last Updated: 19 Aug 2013

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Hyperoxaluria after modern bariatric surgery: case series and literature review.
 

Author(s): Jared M Whitson, G Bennett Stackhouse, Marshall L Stoller

Journal: Int Urol Nephrol. 2010 Jun;42(2):369-74.

 

Two recent studies have shown that modern bariatric surgery leads to significant hyperoxaluria and risk of nephrolithiasis. However, neither report evaluates the use or effects of stone risk modifying agents in these patients. We sought to determine the impact of medical management ...

Last Updated: 17 Jun 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Patients With Primary Hyperoxaluria
 

Status: Recruiting

Condition Summary: Primary Hyperoxaluria

 

Last Updated: 4 Sep 2014

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Last Updated: 4 Sep 2014

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Biobank Protocol, Rare Diseases Clinical Research Network
 

Status: Recruiting

Condition Summary: Primary Hyperoxaluria; Dent Disease; APRT Deficiency; Cystinuria

 

Last Updated: 16 Sep 2014

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