Hydrocephalus

Common Name(s)

Hydrocephalus

Hydrocephalus is a condition characterized by excessive accumulation of fluid in the brain. Although it was once known as "water on the brain," the "water" is actually cerebrospinal fluid (CSF) - clear fluid that surrounds the brain and spinal cord. Excess CSF builds up when it cannot drain from the brain due to a blockage in a passage through which the fluid normally flows.  This excess fluid causes an abnormal widening of spaces in the brain called ventricles; this can create harmful pressure on brain tissue. Symptoms vary with age, disease progression, and individual differences in tolerance to the condition. Hydrocephalus may be congenital (present at birth) or acquired. The causes are not fully understood; it may result from inherited genetic abnormalities or developmental disorders; complications of premature birth; diseases such as meningitis; tumors; traumatic head injury; or other causes. It is most often treated by surgically inserting a shunt system.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydrocephalus" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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Hydrocephalus Association

The Hydrocephalus Association’s goal is to eliminate the challenges of hydrocephalus by stimulating innovative research and providing support, education and advocacy for individuals, families and professionals dealing with the complex issues of the condition.

Last Updated: 19 Nov 2012

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Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

Last Updated: 15 Apr 2014

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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Spina Bifida Resource

Spina Bifida Resource's mission is to promote the prevention of spina bifida and its secondary conditions and to enhance the health and well-being of those affected.

Last Updated: 15 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydrocephalus" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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Hydrocephalus Association

The Hydrocephalus Association’s goal is to eliminate the challenges of hydrocephalus by stimulating innovative research and providing support, education and advocacy for individuals, families and professionals dealing with the complex issues of the condition.

http://www.hydroassoc.org

Last Updated: 19 Nov 2012

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Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

http://www.mofamilytofamily.org

Last Updated: 15 Apr 2014

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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Spina Bifida Resource

Spina Bifida Resource's mission is to promote the prevention of spina bifida and its secondary conditions and to enhance the health and well-being of those affected.

http://spinabifidaresource.weebly.com/

Last Updated: 15 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hydrocephalus" returned 795 free, full-text research articles on human participants. First 3 results:

Influence of the hole geometry on the flow distribution in ventricular catheters for hydrocephalus.
 

Author(s): Ángel Giménez, Marcelo Galarza, Olga Pellicer, José Valero, José M Amigó

Journal:

 

Hydrocephalus is a medical condition consisting of an abnormal accumulation of cerebrospinal fluid within the brain. A catheter is inserted in one of the brain ventricles and then connected to an external valve to drain the excess of cerebrospinal fluid. The main drawback of this ...

Last Updated: 26 Jul 2016

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Cysticerci located in the fourth ventricle causing obstructive hydrocephalus: a radiological emergency requiring prompt diagnosis.
 

Author(s): Lucas Giansante Abud, Tanaka Koji, Thiago Giansante Abud

Journal: Rev. Soc. Bras. Med. Trop.. 2016 Apr;49(2):263.

 

Last Updated: 19 May 2016

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Ventriculoperitoneal (VP) Shunt Survival in Patients Developing Hydrocephalus After Cranial Surgery.
 

Author(s): Farid Khan, Abdul Rehman, Muhammad Shahzad Shamim, Muhammad Ehsan Bari

Journal: Turk Neurosurg. ;26(3):369-77.

 

Ventriculoperitoneal (VP) shunt insertion remains the most popular method for the treatment of hydrocephalus despite its associated complications. We assessed VP shunt survival in a group of patients who had developed hydrocephalus following cranial surgery.

Last Updated: 10 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hydrocephalus" returned 52 free, full-text review articles on human participants. First 3 results:

Nonsurgical therapy for hydrocephalus: a comprehensive and critical review.
 

Author(s): Marc R Del Bigio, Domenico L Di Curzio

Journal:

 

Pharmacological interventions have been tested experimentally and clinically to prevent hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of varied quality have not demonstrated lasting and convincing protective effects through manipulation of cerebrospinal ...

Last Updated: 5 Feb 2016

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Impact of operation details on hydrocephalus after decompressive craniectomy.
 

Author(s): Qiang-Ping Wang, Jun-Peng Ma, Zhang-Ming Zhou, Chao You

Journal: Neurosciences (Riyadh). 2016 Jan;21(1):10-6.

 

To evaluate the correlation between the distance of craniectomy from the midline and hydrocephalus after DC.

Last Updated: 28 Jan 2016

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A review of cognitive impairment and differential diagnosis in idiopathic normal pressure hydrocephalus.
 

Author(s): Marta Picascia, Roberta Zangaglia, Sara Bernini, Brigida Minafra, Elena Sinforiani, Claudio Pacchetti

Journal: Funct. Neurol.. ;30(4):217-28.

 

Idiopathic normal pressure hydrocephalus (iNPH) is a complex and still underestimated pathology. In the early stages, the cognitive profile is characterized mainly by impairments of attention, psychomotor speed and memory, suggesting frontal involvement; patients with more advanced ...

Last Updated: 5 Jan 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Nov 2016

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A Randomized Cross-over Study for Normal Pressure Hydrocephalus
 

Status: Recruiting

Condition Summary: Normal Pressure Hydrocephalus

 

Last Updated: 17 Mar 2015

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Study of Choroid Plexus Cauderization in Patients With Hydrocephalus
 

Status: Not yet recruiting

Condition Summary: Hydrocephalus

 

Last Updated: 26 Sep 2016

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