Hydatidiform mole

Common Name(s)

Hydatidiform mole, Gestational Trophoblastic Neoplasms

Molar pregnancy is a condition in which the placenta does not develop properly. The symptoms of molar pregnancy, which may include vaginal bleeding, severe morning sickness, stomach cramps, and high blood pressure, typically begin around the 10th week of pregnancy. Because the embryo does not form or is malformed in molar pregnancies, and because there is a small risk of developing a cancer called choriocarcinoma, a D&C is usually performed.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydatidiform mole" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydatidiform mole" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hydatidiform mole" returned 120 free, full-text research articles on human participants. First 3 results:

Abnormal villous morphology mimicking a hydatidiform mole associated with paternal trisomy of chromosomes 3,7,8 and unipaternal disomy of chromosome 11.
 

Author(s): Neil J Sebire, Philippa C May, Baljeet Kaur, Michael J Seckl, Rosemary A Fisher

Journal:

 

Pregnancies affected by non-molar chromosomal abnormality may sometimes demonstrate abnormal chorionic villous morphology that is similar to partial hydatidiform mole. Determination of the underlying aetiology may be difficult in such cases.

Last Updated: 5 Feb 2016

Go To URL
Early Detection by Ultrasound of Partial Hydatidiform Mole With a Coexistent Live Fetus.
 

Author(s): Kanika Gupta, Bhuvaneswari Venkatesan, Meenakshisundaram Kumaresan, Tushar Chandra

Journal: WMJ. 2015 Oct;114(5):208-11; quiz 212.

 

Twin pregnancy with hydatidiform mole and coexistent live fetus is a rare condition with severe maternal and fetal complications such as preeclampsia, vaginal bleeding, persistent gestational trophoblastic tumor, and fetal death.

Last Updated: 1 Jan 2016

Go To URL
Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole.
 

Author(s): Kyu Rae Kim, Chang Ohk Sung, Tae Jeong Kwon, JungBok Lee, Stanley J Robboy

Journal:

 

The pathogenetic mechanism underlying the hydropic change in complete hydatidiform moles (CHMs) is poorly understood. A growing body of data suggests that pericytes play a role in vascular maturation. Since maturation of villous stromal vessels in CHMs is markedly impaired at early ...

Last Updated: 8 Apr 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hydatidiform mole" returned 7 free, full-text review articles on human participants. First 3 results:

[Complete hydatidiform mole].
 

Author(s): Jean-Jacques Candelier

Journal: Med Sci (Paris). 2015 Oct;31(10):861-8.

 

"The battle of the sexes begins in the zygote" W. Reik and J. Walter. Complete hydatidiform mole (CHM) is a pathology of the placenta with androgenetic diploid origin (chromosomes only from paternal origin). Placental villi present an abnormal hyperproliferation and hydropic degeneration ...

Last Updated: 20 Oct 2015

Go To URL
A case of true tubal hydatidiform mole and literature review.
 

Author(s): A Siozos, A Sriemevan

Journal:

 

Tubal hydatidiform mole is an uncommon condition with about 40 confirmed cases in the accessible literature. The patient usually presents with symptoms and signs of a classical ectopic pregnancy and it is only after histological examination and DNA ploidy analysis of the conceptus ...

Last Updated: 6 Jul 2012

Go To URL
[Hydatidiform mole and gestational trophoblastic disease].
 

Author(s): Jurandyr Moreira de Andrade

Journal: Rev Bras Ginecol Obstet. 2009 Feb;31(2):94-101.

 

The hydatiform mole is a relatively rare pregnancy complication, but with potential to evolve to forms which need systemic treatment and can be a threat to life. There are two histopathological and clinical entities under the name of hydatiform mole: the partial and the complete mole. ...

Last Updated: 1 May 2009

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole
 

Status: Recruiting

Condition Summary: Hydatidiform Mole

 

Last Updated: 22 Mar 2016

Go to URL
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles
 

Status: Recruiting

Condition Summary: Hydatidiform Moles

 

Last Updated: 16 Jun 2016

Go to URL
The French National Reference Centre of GTD
 

Status: Recruiting

Condition Summary: Neoplasm, Trophoblastic; Gestational Trophoblastic Disease; Hydatidiform Mole; Hydatidiform Mole, Invasive

 

Last Updated: 2 Sep 2016

Go to URL