Human parvovirus B19 infection

Common Name(s)

Human parvovirus B19 infection, Fifth disease

Human parvovirus B19 infections, also known as fifth disease, is an infection by a specific virus that only affects humans. Parvovirus is highly contagious in children and causes a rash on the face which due to its appearance is called a "slap rash". Usually infections in children do not last very long and the associated rash can be treated at home with over the counter anti-rash remedies. Adults may also get parvovirus but their symptoms are usually limited to joint pain and immobility. People with weakened immune systems caused by leukemia, cancer, organ transplants, or HIV infection are at risk for serious complications from fifth disease. It can cause chronic anemia that requires medical treatment.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Human parvovirus B19 infection" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Human parvovirus B19 infection" returned 62 free, full-text research articles on human participants. First 3 results:

Human parvovirus B19 infection leads to downregulation of thyroid, estrogen, and retinoid hormone receptor expression.
 

Author(s): Igor V Ignatovich, Jacqueline A Hobbs

Journal: Virology. 2013 Nov;446(1-2):173-9.

 

Erythrovirus B19 (B19V) is a member of the family Parvoviridae. Infection with B19V has been linked to a variety of diseases including erythroid, thyroid, neurological and autoimmune diseases. Here we show that infection of primary CD36+ cells with B19V coincides with downregulation ...

Last Updated: 30 Sep 2013

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Human parvovirus B19 infection causes cell cycle arrest of human erythroid progenitors at late S phase that favors viral DNA replication.
 

Author(s): Yong Luo, Steve Kleiboeker, Xuefeng Deng, Jianming Qiu

Journal: J. Virol.. 2013 Dec;87(23):12766-75.

 

Human parvovirus B19 (B19V) infection has a unique tropism to human erythroid progenitor cells (EPCs) in human bone marrow and the fetal liver. It has been reported that both B19V infection and expression of the large nonstructural protein NS1 arrested EPCs at a cell cycle status ...

Last Updated: 4 Nov 2013

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Co-infection of human parvovirus B19 with Plasmodium falciparum contributes to malaria disease severity in Gabonese patients.
 

Author(s): Nguyen L Toan, Bui T Sy, Le H Song, Hoang V Luong, Nguyen T Binh, Vu Q Binh, Reinhard Kandolf, Thirumalaisamy P Velavan, Peter G Kremsner, C-Thomas Bock

Journal:

 

High seroprevalence of parvovirus B19 (B19V) coinfection with Plasmodium falciparum has been previously reported. However, the impact of B19V-infection on the clinical course of malaria is still elusive. In this study, we investigated the prevalence and clinical significance of B19V ...

Last Updated: 26 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Human parvovirus B19 infection" returned 6 free, full-text review articles on human participants. First 3 results:

Intravenous immunoglobulin therapy for pure red cell aplasia related to human parvovirus b19 infection: a retrospective study of 10 patients and review of the literature.
 

Author(s): Yoann Crabol, Benjamin Terrier, Flore Rozenberg, Vincent Pestre, Christophe Legendre, Olivier Hermine, Catherine Montagnier-Petrissans, Loïc Guillevin, Luc Mouthon,

Journal: Clin. Infect. Dis.. 2013 Apr;56(7):968-77.

 

We evaluated the efficacy of intravenous immunoglobulin (IVIG) therapy in patients with pure red cell aplasia (PRCA) related to human parvovirus B19 (HPV-B19) infection.

Last Updated: 6 Mar 2013

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Parvovirus B19 infection in human pregnancy.
 

Author(s): R F Lamont, J D Sobel, E Vaisbuch, J P Kusanovic, S Mazaki-Tovi, S K Kim, N Uldbjerg, R Romero

Journal: BJOG. 2011 Jan;118(2):175-86.

 

Human parvovirus B19 infection is widespread. Approximately 30-50% of pregnant women are nonimmune, and vertical transmission is common following maternal infection in pregnancy. Fetal infection may be associated with a normal outcome, but fetal death may also occur without ultrasound ...

Last Updated: 16 Dec 2010

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[Various clinical symptoms in human parvovirus B19 infection].
 

Author(s): Kotaro Kumano

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2008 Dec;31(6):448-53.

 

Human parvovirus B19 infection causes erythema infectiosum in child, aplastic crisis in patients with chronic hemolytic anemia, chronic pure red cell aplasia in immunocompromised patients and hydrops fetalis. Human parvovirus B19 causes arthritis and acute glomerulonephritis due to ...

Last Updated: 5 Jan 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease
 

Status: Recruiting

Condition Summary: Sickle Cell Disease

 

Last Updated: 21 Oct 2014

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