Alveolar Soft Part Sarcoma

Common Name(s)

Alveolar Soft Part Sarcoma

Alveolar soft part sarcoma is an unusual tumor with highly characteristic histopathology and ultrastructure, controversial histogenesis, and enigmatic clinical behavior ({3:Lieberman et al., 1989}; {4:Ordonez, 1999}). The typical histology of ASPS shows well-defined nests of cells with abundant pink cytoplasm. The loss of central cohesion produces a pseudoalveolar appearance ({2:Ladanyi et al., 2001}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alveolar Soft Part Sarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alveolar Soft Part Sarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alveolar Soft Part Sarcoma" returned 82 free, full-text research articles on human participants. First 3 results:

Alveolar soft part sarcoma occurring in the penis of a 3-year-old boy: A rare case report.
 

Author(s): Linli Qiu, Yuman Li, Shima Ibrahim Ali, Mingxing Xie

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8383.

 

Alveolar soft part sarcoma (ASPS) is a rare, malignant neoplasm, which mostly occurs in the upper and lower extremities. This article presents an unusual case of ASPS involving the penis of a 3-year-old boy. To our knowledge, this is the first case of ASPS in the penis of a child.

Last Updated: 31 Dec 1969

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Lingual alveolar soft part sarcoma responsive to pazopanib: A case report.
 

Author(s): Tomoyasu Yoshihiro, Kenji Tsuchihashi, Kenta Nio, Shuji Arita, Takafumi Nakano, Ryuji Yasumatsu, Rina Jiroumaru, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba

Journal: Medicine (Baltimore). 2017 Nov;96(44):e8470.

 

The multi-targeted tyrosine kinase inhibitors such as cediranib, sunitinib and pazopanib have been reported to be effective for alveolar soft part sarcoma (ASPS). The efficacy of pazopanib for the patient with lingual ASPS has yet to be reported.

Last Updated: 31 Dec 1969

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Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma.
 

Author(s): Kenta Mukaihara, Yu Tanabe, Daisuke Kubota, Keisuke Akaike, Takuo Hayashi, Kaoru Mogushi, Masaki Hosoya, Shingo Sato, Eisuke Kobayashi, Taketo Okubo, Youngji Kim, Shinji Kohsaka, Tsuyoshi Saito, Kazuo Kaneko, Yoshiyuki Suehara

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Alveolar soft part sarcoma (ASPS) is an extremely rare metastatic soft tissue tumor with a poor prognosis for which no effective systemic therapies have yet been established. Therefore, the development of novel effective treatment approaches is required. Tyrosine kinases (TKs) are ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alveolar Soft Part Sarcoma" returned 9 free, full-text review articles on human participants. First 3 results:

Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy: A case report and literature review.
 

Author(s): Yubo Wang, Jiayue Cui, Xu Yan, Rihua Jin, Xinyu Hong

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8790.

 

Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.

Last Updated: 31 Dec 1969

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Surgical management and outcome of spinal alveolar soft part sarcoma (ASPA): a case series of five patients and literature review.
 

Author(s): Chenglong Zhao, Xin Gao, Jian Yang, Zhenxi Li, Xiaopan Cai, Tao Tan, Tianhui Hou, Wangjun Yan, Xinghai Yang, Cheng Yang, Tielong Liu, Jianru Xiao

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Alveolar soft part sarcoma (ASPS) is a rare entity of soft tissue malignancies with uncommon spinal involvements. Surgical management should be the best choice of cure.

Last Updated: 31 Dec 1969

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Primary alveolar soft part sarcoma of uterine corpus: a case report with immunohistochemical, ultrastructural study and review of literature.
 

Author(s): Giovanna Giordano, Tiziana D'Adda, Elena Varotti, Giuseppe Crovini, Enrico Maria Silini

Journal:

 

Alveolar soft part sarcoma (ASPS) is a rare mesenchymal malignancy. ASPS usually occurs most commonly in the deep soft tissues of the thigh and buttock or the head and neck regions. ASPS that originate from the uterine corpus are even more rare, with only 10 previous cases reported ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Dec 2017

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Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas
 

Status: Recruiting

Condition Summary: Alveolar Soft Part Sarcoma; Soft Tissue Sarcomas

 

Last Updated: 8 Sep 2017

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A Phase III Trial of Anlotinib in Metastatic or Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma and Synovial Sarcoma
 

Status: Recruiting

Condition Summary: Alveolar Soft Part Sarcoma; Leiomyosarcoma; Synovial Sarcoma; Soft-Tissue Sarcoma

 

Last Updated: 27 Nov 2017

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