Hodgkin lymphoma

Common Name(s)

Hodgkin lymphoma, Hodgkin's disease

Hodgkin lymphoma is a cancer of the lymph tissue, which can be found in the lymph nodes, spleen and other organs of the immune system. There are two types of Hodgkin lymphoma, which are known as nodular and classical Hodgkin’s. The classical form is further divided into four subtypes and is characterized by the presence of what are known as "Reed–Sternberg cells" (overgrown B-cells). Although Hodgkin lymphoma starts in the bone marrow, it may also spread to other tissues of the body, depending on the stage and how aggressive the type is. Anyone can get Hodgkin lymphoma, but there are some factors that increase one’s risks. People who have or have had the Epstein-Barr virus (also known as mono or mononucleosis) or HIV are at an increased risk, as well as those with a family history of the condition. Additionally, males, young adults and the elderly, and people from the U.S., Canada, or Europe are more likely to develop Hodgkin lymphoma than women, children, or people from other geographic locations.

The most common symptom is one or more enlarged lymph node(s), but enlargement of the spleen or liver may also be a sign. Other symptoms include night sweats, unexplained weight loss, itching, back pain, and red colored patched on the skin. The most effective and commonly used method for diagnosis is a lymph node biopsy, in which the lymph node is cut open and examined. Scans such as the PET or CT scans may be used as well to determine where the cancer is or how far it has spread and the appropriate treatment options. Treatment varies depending on the individual's weight, age, and size as well as the severity of the cancer. Treatment generally involves chemotherapy, radiation, or a combination of the two. Talk to your doctor if you are experiencing any symptoms or think you have Hodgkin lymphoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

View Details
National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

View Details
The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

View Details
The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

http://www.hodgkinsfoundation.org

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hodgkin lymphoma" returned 1614 free, full-text research articles on human participants. First 3 results:

Ileocecal Obstruction Due to B-cell Non-Hodgkin Lymphoma.
 

Author(s): Vasile Negrean, Florin Graur, Emil Moiş, Nadim Al-Hajjar,

Journal: Chirurgia (Bucur). ;111(1):71-3.

 

We report a rare case of non-Hodgkin lymphoma presented as an ileocecal mass. The patient was a 77-year-old man with history of symptoms of partial bowel obstruction, intermittent right iliac fossa pain, loss of weight, vomiting and fatigue. Clinical signs included moderate abdominal ...

Last Updated: 18 Mar 2016

Go To URL
Gemcitabine-Based Treatment in Poor-Prognosis Patients with Relapsed and Refractory Hodgkin Lymphoma and Non-Hodgkin Lymphoma--a Multicenter Polish Experience.
 

Author(s): Justyna Rybka, Wojciech Jurczak, Agnieszka Giza, Ewa Paszkiewicz-Kozik, Beata Kumiega, Joanna Drozd-Sokołowska, Aleksandra Butrym, Kazimierz Kuliczkowski, Tomasz Wróbel

Journal: Adv Clin Exp Med. ;24(5):783-9.

 

The treatment of patients with relapsed or refractory Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) remains challenging. Gemcitabine is a cytidine analog with a wide spectrum of antitumor activity. Gemcitabine treatment is widely used to treat patients with certain solid ...

Last Updated: 15 Jan 2016

Go To URL
A 20-year population-based study on the epidemiology, clinical features, treatment, and outcome of nodular lymphocyte predominant Hodgkin lymphoma.
 

Author(s): L Strobbe, L L F G Valke, I J Diets, M van den Brand, K Aben, J M M Raemaekers, K M Hebeda, J H J M van Krieken

Journal: Ann. Hematol.. 2016 Feb;95(3):417-23.

 

Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a subtype of Hodgkin lymphoma characterized by a unique clinical and histological presentation. Because of the rare nature of this disease, few large-scale studies are available. We conducted a cohort study in which patients ...

Last Updated: 5 Feb 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hodgkin lymphoma" returned 120 free, full-text review articles on human participants. First 3 results:

Bilateral hand squamous-cells carcinoma in patient affected with non-Hodgkin lymphoma. Case report and literature review.
 

Author(s): P Fino, A M Spagnoli, M Ruggieri, M Marcasciano, N Scuderi

Journal: G Chir. ;36(4):172-82.

 

Squamous-cell skin cancer is the most frequent tumor in the hand. It occurs on sun-damaged skin, especially in lightskinned individuals with a long history of chronic sun exposure.

Last Updated: 29 Dec 2015

Go To URL
Red and Processed Meat Consumption Increases Risk for Non-Hodgkin Lymphoma: A PRISMA-Compliant Meta-Analysis of Observational Studies.
 

Author(s): Li Yang, Jianming Dong, Shenghua Jiang, Wenyu Shi, Xiaohong Xu, Hongming Huang, Xuefen You, Hong Liu

Journal: Medicine (Baltimore). 2015 Nov;94(45):e1729.

 

The association between consumption of red and processed meat and non-Hodgkin lymphoma (NHL) remains unclear. We performed a meta-analysis of the published observational studies to explore this relationship.We searched databases in MEDLINE and EMBASE to identify observational studies ...

Last Updated: 12 Nov 2015

Go To URL
Systematic review and meta-analysis on the prognostic value of complete remission status at FDG-PET in Hodgkin lymphoma after completion of first-line therapy.
 

Author(s): Hugo J A Adams, Rutger A J Nievelstein, Thomas C Kwee

Journal: Ann. Hematol.. 2016 Jan;95(1):1-9.

 

This study aimed to systematically review and meta-analyze the prognostic value of complete remission status at 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) in Hodgkin lymphoma after completion of first-line therapy. A systematic literature search was performed ...

Last Updated: 26 Apr 2016

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Gemcitabine and Bendamustine in Patients With Relapsed or Refractory Hodgkin's Lymphoma
 

Status: Recruiting

Condition Summary: Adult Lymphocyte Depletion Hodgkin Lymphoma; Adult Lymphocyte Predominant Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin Lymphoma; Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma; Adult Nodular Sclerosis Hodgkin Lymphoma; Recurrent Adult Hodgkin Lymphoma

 

Last Updated: 20 Oct 2015

Go to URL
Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphoma
 

Status: Recruiting

Condition Summary: Stage II Childhood Hodgkin Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage IV Childhood Hodgkin Lymphoma

 

Last Updated: 24 Mar 2016

Go to URL
Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma
 

Status: Recruiting

Condition Summary: AIDS-Related Hodgkin Lymphoma; Classical Hodgkin Lymphoma; HIV Infection; Stage IIA Hodgkin Lymphoma; Stage IIB Hodgkin Lymphoma; Stage IIIA Hodgkin Lymphoma; Stage IIIB Hodgkin Lymphoma; Stage IVA Hodgkin Lymphoma; Stage IVB Hodgkin Lymphoma

 

Last Updated: 25 May 2016

Go to URL