Hodgkin lymphoma

Common Name(s)

Hodgkin lymphoma, Hodgkin's disease

Hodgkin lymphoma is a cancer of the lymph tissue, which can be found in the lymph nodes, spleen and other organs of the immune system. There are two types of Hodgkin lymphoma, which are known as nodular and classical Hodgkin’s. The classical form is further divided into four subtypes and is characterized by the presence of what are known as "Reed–Sternberg cells" (overgrown B-cells). Although Hodgkin lymphoma starts in the bone marrow, it may also spread to other tissues of the body, depending on the stage and how aggressive the type is. Anyone can get Hodgkin lymphoma, but there are some factors that increase one’s risks. People who have or have had the Epstein-Barr virus (also known as mono or mononucleosis) or HIV are at an increased risk, as well as those with a family history of the condition. Additionally, males, young adults and the elderly, and people from the U.S., Canada, or Europe are more likely to develop Hodgkin lymphoma than women, children, or people from other geographic locations.

The most common symptom is one or more enlarged lymph node(s), but enlargement of the spleen or liver may also be a sign. Other symptoms include night sweats, unexplained weight loss, itching, back pain, and red colored patched on the skin. The most effective and commonly used method for diagnosis is a lymph node biopsy, in which the lymph node is cut open and examined. Scans such as the PET or CT scans may be used as well to determine where the cancer is or how far it has spread and the appropriate treatment options. Treatment varies depending on the individual's weight, age, and size as well as the severity of the cancer. Treatment generally involves chemotherapy, radiation, or a combination of the two. Talk to your doctor if you are experiencing any symptoms or think you have Hodgkin lymphoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

View Details
The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

http://www.hodgkinsfoundation.org

Last Updated: 15 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hodgkin lymphoma" returned 1640 free, full-text research articles on human participants. First 3 results:

Treatment patterns and costs of care for patients with relapsed and refractory Hodgkin lymphoma treated with brentuximab vedotin in the United States: A retrospective cohort study.
 

Author(s): Shelagh M Szabo, Ishan Hirji, Karissa M Johnston, Ariadna Juarez-Garcia, Joseph M Connors

Journal:

 

Although brentuximab vedotin (BV) has changed the management of patients with relapsed or refractory Hodgkin lymphoma (RRHL), little information is available on routine clinical practice. We identified treatment patterns and costs of care among RRHL patients in the United States (US) ...

Last Updated: 9 Oct 2017

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Anti-Ma2-associated limbic encephalitis with coexisting chronic inflammatory demyelinating polyneuropathy in a patient with non-Hodgkin lymphoma: A case report.
 

Author(s): Weina Ju, Baochang Qi, Xu Wang, Yu Yang

Journal: Medicine (Baltimore). 2017 Oct;96(40):e8228.

 

We report the rare case of a 74-year-old man with anti-Ma2-associated paraneoplastic neurologic syndrome (PNS), and review and analyze the clinical manifestations, diagnosis, and treatment of the disease.

Last Updated: 6 Oct 2017

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Classic Hodgkin lymphoma in pelvis: A case report highlights diagnosis and treatment challenges.
 

Author(s): Fan Tang, Li Min, Yunxia Ye, Bo Tang, Yong Zhou, Wenli Zhang, Chongqi Tu

Journal: Medicine (Baltimore). 2017 Sep;96(39):e8196.

 

Classic Hodgkin lymphoma with pelvic involvement is a rare entity. Diagnosis and treatment for such an uncommon disease are challenging. Here we report a special case of classic Hodgkin lymphoma in pelvis.

Last Updated: 27 Sep 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hodgkin lymphoma" returned 147 free, full-text review articles on human participants. First 3 results:

Model-based meta-analysis of progression-free survival in non-Hodgkin lymphoma patients.
 

Author(s): Mengyao Li, Nimita Dave, Ahmed Hamed Salem, Kevin J Freise

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7988.

 

Non-Hodgkin lymphoma (NHL) is a group of lymphoproliferative malignancies with varying treatment responses and progression-free survival (PFS) times. The objective of this study was to quantify the effect of treatment and patient-population characteristics on PFS in patients with NHL.

Last Updated: 31 Aug 2017

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Primary adrenal non-Hodgkin lymphoma: a case report and review of the literature.
 

Author(s): Nanik Ram, Owais Rashid, Saad Farooq, Imran Ulhaq, Najmul Islam

Journal:

 

Lymphomas are cancers that arise from the white blood cells and have been traditionally divided into two large subtypes: Hodgkin and non-Hodgkin lymphoma. B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma; almost 85% of patients with lymphoma have this variant. Lymphomas ...

Last Updated: 15 Apr 2017

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Clinical development of anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma.
 

Author(s): Shinichi Makita, Kiyoshi Yoshimura, Kensei Tobinai

Journal: Cancer Sci.. 2017 Jun;108(6):1109-1118.

 

B-cell non-Hodgkin lymphoma (B-NHL) is the most frequent hematological malignancy. Although refined chemotherapy regimens and several new therapeutics including rituximab, a chimeric anti-CD20 monoclonal antibody, have improved its prognosis in recent decades, there are still a substantial ...

Last Updated: 16 Mar 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Sep 2017

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Brazilian Prospective Hodgkin Lymphoma Registry
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma; Hodgkin Disease

 

Last Updated: 10 May 2016

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SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma

 

Last Updated: 15 Aug 2017

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