Histiocytosis

Common Name(s)

Histiocytosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Histiocytosis" for support, advocacy or research.

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Histiocytosis Association

The Histiocytosis Association is dedicated to raising awareness about histiocytic disorders, providing educational and emotional support, and funding research leading to better treatments and a cure.

Last Updated: 30 Oct 2012

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Histiocytosis" for support, advocacy or research.

Logo
Histiocytosis Association

The Histiocytosis Association is dedicated to raising awareness about histiocytic disorders, providing educational and emotional support, and funding research leading to better treatments and a cure.

http://www.histio.org

Last Updated: 30 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Histiocytosis" returned 592 free, full-text research articles on human participants. First 3 results:

Clinicopathological features and BRAF(V600E) mutations in patients with isolated hypothalamic-pituitary Langerhans cell histiocytosis.
 

Author(s): Zhen Huo, Tao Lu, Zhiyong Liang, Fan Ping, Jie Shen, Jingjing Lu, Wenbing Ma, Dachun Zhao, Dingrong Zhong

Journal:

 

Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAF(V600E) mutations and treatments of isolated HPLCH.

Last Updated: 20 Oct 2016

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Pulmonary Langerhans Cell Histiocytosis and Diabetes Insipidus in a Young Smoker.
 

Author(s): K Earlam, C A Souza, R Glikstein, M M Gomes, S Pakhalé

Journal: Can. Respir. J.. 2016 ;2016():3740902.

 

Langerhans cell histiocytosis is characterized by the abnormal nodular proliferation of histiocytes in various organ systems. Pulmonary involvement seen in young adults is nearly always seen in the context of past or current cigarette smoking. Although it tends to be a single-system ...

Last Updated: 22 Jul 2016

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A Case of Pulmonary Langerhans Cell Histiocytosis with BRAF V600E-negative and MAP2K1-posivtive Mutations Presenting as Diffuse Nodules in Chest High-resolution Computed Tomography After Smoking Cessation.
 

Author(s): Yan Li, Hou-Rong Cai, Miao Ma, Li-Jing Wang, Jun Yang, Jing-Jing Ding, Li-Yun Miao

Journal: Chin. Med. J.. 2016 Jun;129(11):1384-6.

 

Last Updated: 27 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Histiocytosis" returned 75 free, full-text review articles on human participants. First 3 results:

Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma: Current Understanding and Differential Diagnosis.
 

Author(s): Hirokazu Nakamine, Mitsunori Yamakawa, Tadashi Yoshino, Takaya Fukumoto, Yasunori Enomoto, Itaru Matsumura

Journal: J Clin Exp Hematop. 2016 ;56(2):109-118.

 

Langerhans cell (LC) histiocytosis (LCH) and LC sarcoma (LCS) are proliferative processes consisting of cells having morphologic and phenotypic features of Langerhans cells (LCs), although the latter may have lost some of these features. Because neoplastic nature of LCH as well as ...

Last Updated: 16 Dec 2016

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Langerhans cell histiocytosis in adults: a case report and review of the literature.
 

Author(s): Cuihong Lian, Yuan Lu, Siyuan Shen

Journal: Oncotarget. 2016 Apr;7(14):18678-83.

 

Langerhans cell histiocytosis (LCH) is a proliferative disease of histiocyte-like cells that generally affects children. Immunohistochemistry is essential to obtain the correct diagnosis, and treatment protocols are controversial.

Last Updated: 14 Jul 2016

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Langerhans Cell Histiocytosis: Emerging Insights and Clinical Implications.
 

Author(s): Daniel J Zinn, Rikhia Chakraborty, Carl E Allen

Journal: Oncology (Williston Park, N.Y.). 2016 Feb;30(2):122-32, 139.

 

Langerhans cell histiocytosis is a disorder characterized by lesions that include CD207+ dendritic cells along with an inflammatory infiltrate. Langerhans cell histiocytosis has a highly variable clinical presentation, ranging from a single lesion to potentially fatal disseminated ...

Last Updated: 18 Feb 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase II Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis
 

Status: Recruiting

Condition Summary: Langerhans Cell Histiocytosis

 

Last Updated: 4 Aug 2016

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Last Updated: 17 Nov 2016

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Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
 

Status: Recruiting

Condition Summary: Langerhans Cell Histiocytosis

 

Last Updated: 10 Mar 2015

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