Histiocytosis

Common Name(s)

Histiocytosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Histiocytosis" for support, advocacy or research.

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Histiocytosis Association

The Histiocytosis Association is dedicated to raising awareness about histiocytic disorders, providing educational and emotional support, and funding research leading to better treatments and a cure.

Last Updated: 30 Oct 2012

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Histiocytosis" for support, advocacy or research.

Logo
Histiocytosis Association

The Histiocytosis Association is dedicated to raising awareness about histiocytic disorders, providing educational and emotional support, and funding research leading to better treatments and a cure.

http://www.histio.org

Last Updated: 30 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Histiocytosis" returned 441 free, full-text research articles on human participants. First 3 results:

Antiphospholipid syndrome and Langerhans cell histiocytosis: an exceptional association.
 

Author(s): Hamida Kwas, Ines Zendah, Ayda Bayoudh, Asma Zidi, Habib Ghédira

Journal: Tunis Med. 2014 Nov;92(11):697-8.

 

Last Updated: 14 Apr 2015

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[Cladribine for 13 cases refractory high-risk children Langerhans cell histiocytosis].
 

Author(s): Tao Hu, Rong Liu, Junhui Li, Jing Cao, Lei Zhang, Juanjuan Li, Wei Fan, Dixiao Zhong, Xiaodong Shi

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Nov;35(11):985-9.

 

To observe the efficacy and adverse reaction of the improvement program of cladribine combined with cytarabine (2-CdA+Ara-C) in treatment of children with refractory high-risk Langerhans cell histiocytosis (LCH).

Last Updated: 24 Nov 2014

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Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions.
 

Author(s): Jennifer A West, Sharon L Olsen, Jenée M Mitchell, Ross E Priddle, Jennifer M Luke, Selma Olsson Akefeldt, Jan-Inge Henter, Christopher Turville, George Kannourakis

Journal:

 

Langerhans cell histiocytosis (LCH) is a complex and poorly understood disorder that has characteristics of both inflammatory and neoplastic disease. By using eight-colour flow cytometry, we have identified a previously unreported population of CD1a(+)/CD3(+) T-cells in LCH lesions. ...

Last Updated: 25 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Histiocytosis" returned 51 free, full-text review articles on human participants. First 3 results:

Langerhans cell histiocytosis.
 

Author(s): Nanette Grana

Journal: Cancer Control. 2014 Oct;21(4):328-34.

 

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric ...

Last Updated: 14 Oct 2014

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Histiocytosis: a review focusing on neuroimaging findings.
 

Author(s): Larissa Barcessat Gabbay, Cláudia da Costa Leite, Ranieli Saraiva Andriola, Paula da Cunha Pinho, Leandro Tavares Lucato

Journal: Arq Neuropsiquiatr. 2014 Jul;72(7):548-58.

 

Histiocytosis is a systemic disease that usually affects the central nervous system. The aim of this study is to discuss the neuroimaging characteristics of Langerhans cell histiocytosis (LCH), the most common of these diseases; and the non-Langerhans cells histiocytosis (NLCH), which ...

Last Updated: 24 Jul 2014

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The adverse prognostic hallmarks in identical twins with Langerhans cell histiocytosis: a clinical report and literature review.
 

Author(s): Damin Chai, Yisheng Tao, Zhengqi Bao, Li Yang, Zhenzhong Feng, Li Ma, Limei Liang, Xinwen Zhou

Journal: Tohoku J. Exp. Med.. 2013 ;230(4):219-25.

 

Langerhans cell histiocytosis (LCH) is characterized by uncontrolled proliferation of Langerhans cells accompanying eosinophils. It often attacks children under 10 years of age. LCH in identical twins is very rare and its prognosis is different. Here we report identical-twin sisters ...

Last Updated: 8 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase II Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis
 

Status: Not yet recruiting

Condition Summary: Langerhans Cell Histiocytosis

 

Last Updated: 21 Apr 2015

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Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
 

Status: Recruiting

Condition Summary: Langerhans Cell Histiocytosis

 

Last Updated: 10 Mar 2015

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LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
 

Status: Not yet recruiting

Condition Summary: Langerhans Cell Histiocytosis

 

Last Updated: 30 Jul 2014

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