Shingles

Common Name(s)

Shingles, Herpes zoster

Shingles is a painful rash caused by a viral infection. It can occur anywhere on your body, but typically shows up as a single strip of blisters around one side of your torso. Shingles is caused by the varicella-zoster virus, the same virus that also causes chickenpox. If a person had chickenpox in the past, the virus lies inactive (dormant or sleeping) in the nerve tissue near the spinal cord and brain and can reactivate as shingles at a later time. While shingles is not life-threatening, it can be very painful. Shingles generally lasts between two and six weeks. Most people who have shingles only get it once in their life, but it is possible to get it more than once.

Symptoms of shingles includes pain, burning, numbness, sensitivity to touch, red rash, fluid-filled blisters, and itching in the affected area. Some people experience fever, headache, sensitivity to light, and tiredness (fatigue) as well. Risk factors for shingles includes being older than 50, having certain diseases that weaken the immune system (like HIV or cancer), undergoing cancer treatments, and taking medications that weaken your immune system. Vaccines are available which may decrease your risk of shingles.

Your doctor can diagnose shingles by examining the affected area. A sample of affected tissue may be collected and tested to confirm the diagnosis. There is no cure for shingles, but quick treatment with medications that treat viruses (antiviral medications) can speed up the healing process and reduce complications. Your doctor can also provide medications that reduce the pain caused by shingles. If you are diagnosed with shingles, talk with your doctor about the current treatment recommendations.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Shingles" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Shingles" returned 56 free, full-text research articles on human participants. First 3 results:

Insulin-induced localized lipoatrophy preceded by shingles (herpes zoster): a case report.
 

Author(s): Ernst A Chantelau, Ruth Prätor, Jörg Prätor

Journal:

 

Localized involutional lipoatrophy of subcutaneous adipose tissue may develop due to subcutaneous injection of pharmaceutical preparations. The pathogenesis of this adverse drug reaction is unknown. The progression of localized involutional lipoatrophy ceases and occasionally it resolves ...

Last Updated: 9 Jul 2014

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Herpes zoster ophthalmicus reduction: implementation of shingles vaccination in the UK.
 

Author(s): A Potts, G J Williams, J A Olson, K G J Pollock, H Murdoch, J C Cameron

Journal: Eye (Lond). 2014 Mar;28(3):247-8.

 

Last Updated: 13 Mar 2014

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Shingles and statin treatment: confounding by cholesterol or APOE4 status?
 

Author(s): Timo E Strandberg, Pentti Tienari

Journal: Clin. Infect. Dis.. 2014 Apr;58(7):1042-3.

 

Last Updated: 14 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Shingles" returned 5 free, full-text review articles on human participants. First 3 results:

Herpes zoster (shingles) and postherpetic neuralgia.
 

Author(s): Priya Sampathkumar, Lisa A Drage, David P Martin

Journal: Mayo Clin. Proc.. 2009 Mar;84(3):274-80.

 

Herpes zoster (HZ), commonly called shingles, is a distinctive syndrome caused by reactivation of varicella zoster virus (VZV). This reactivation occurs when immunity to VZV declines because of aging or immunosuppression. Herpes zoster can occur at any age but most commonly affects ...

Last Updated: 2 Mar 2009

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Zoster vaccine live for the prevention of shingles in the elderly patient.
 

Author(s): Jamie Zussman, Lorraine Young

Journal: Clin Interv Aging. 2008 ;3(2):241-50.

 

Shingles, also known as herpes zoster, is a common disease in the elderly population that is caused by reactivation of latent varicella zoster virus. Its manifestations and complications can lead to significant short- and long-term morbidity. In 2006, the United States Food and Drug ...

Last Updated: 8 Aug 2008

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Chickenpox, chickenpox vaccination, and shingles.
 

Author(s): P D Welsby

Journal: Postgrad Med J. 2006 May;82(967):351-2.

 

Chickenpox in the United Kingdom, where vaccination is not undertaken, has had a stable epidemiology for decades and is a routine childhood illness. Because of vaccination, chickenpox is now a rarity in the USA. In the UK vaccination is not done because introduction of a routine childhood ...

Last Updated: 8 May 2006

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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of a Live Herpes Zoster Vaccine and a Recombinant Vaccine in 50-59 and 70-85 Year Olds
 

Status: Recruiting

Condition Summary: Adult; Shingles; Herpes Zoster

 

Last Updated: 8 Jun 2015

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A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgia
 

Status: Recruiting

Condition Summary: Shingles; Herpes Zoster; Postherpetic Neuralgia

 

Last Updated: 1 Sep 2015

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Acupuncture in Herpes Zoster Neuralgia (ACUZoster)
 

Status: Recruiting

Condition Summary: Herpes Zoster; Postherpetic Neuralgia; Pain

 

Last Updated: 15 Jan 2015

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