Herpes simplex encephalitis

Common Name(s)

Herpes simplex encephalitis

Herpes simplex is a viral infection of two types, herpes simplex 1 (HS1) and 2 (HS2). HS1 is received through contact with oral secretions (saliva) or skin sores containing the virus. This can be done through kissing and sharing toothbrushes or eating utensils with an individual who has HS1. HS1 causes sores around the mouth and lips. HS2 is received through sexual contact with an individual infected with HS2. HS2 may also be transmitted to a newborn baby during childbirth if the mother is infected with the virus. HS2 can cause genital warts in men and women. Although symptoms can be treated for with medication, there is no cure for herpes. The virus can become dormant in its host for different amounts of time causing outbreaks of symptoms triggered by stress, trauma to the affected area, illness, fatigue, weakening of the immune system.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Herpes simplex encephalitis" for support, advocacy or research.

Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

Last Updated: 19 Feb 2013

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ProjectAccept.org

To gather together all individuals and groups affected by HSV(herpes) & HPV into one social movement; to organize and empower the community in order to fund ProjectAccept.org which will combat HSV & HPV on the following fronts: Awareness: To raise public awareness of both the present and the potential impact of viruses on the uninfected and their loved ones Acceptance: To combat the stigma surrounding HSV & HPV; to make life for the affected easier, while fighting the spread of the viruses through more open communication Virus Research: To combat the disease(s) medically

Last Updated: 15 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Herpes simplex encephalitis" for support, advocacy or research.

Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

http://www.encephalitisglobal.org

Last Updated: 19 Feb 2013

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ProjectAccept.org

To gather together all individuals and groups affected by HSV(herpes) & HPV into one social movement; to organize and empower the community in order to fund ProjectAccept.org which will combat HSV & HPV on the following fronts: Awareness: To raise public awareness of both the present and the potential impact of viruses on the uninfected and their loved ones Acceptance: To combat the stigma surrounding HSV & HPV; to make life for the affected easier, while fighting the spread of the viruses through more open communication Virus Research: To combat the disease(s) medically

http://www.projectaccept.org

Last Updated: 15 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Herpes simplex encephalitis" returned 186 free, full-text research articles on human participants. First 3 results:

Long-term outcome of severe herpes simplex encephalitis: a population-based observational study.
 

Author(s): Youenn Jouan, Leslie Grammatico-Guillon, Fabien Espitalier, Xavier Cazals, Patrick François, Antoine Guillon

Journal:

 

Herpes simplex encephalitis (HSE) is a rare disease with a poor prognosis. No recent evaluation of hospital incidence, acute mortality and morbidity is available. In particular, decompressive craniectomy has rarely been proposed in cases of life-threatening HSE with temporal herniation, ...

Last Updated: 21 Sep 2015

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Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3.
 

Author(s): Shen-Ying Zhang, Jean-Laurent Casanova

Journal: J. Exp. Med.. 2015 Aug;212(9):1342-3.

 

Last Updated: 25 Aug 2015

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Functional IRF3 deficiency in a patient with herpes simplex encephalitis.
 

Author(s): Line Lykke Andersen, Nanna Mørk, Line S Reinert, Emil Kofod-Olsen, Ryo Narita, Sofie E Jørgensen, Kristian A Skipper, Klara Höning, Hans Henrik Gad, Lars Østergaard, Torben F Ørntoft, Veit Hornung, Søren R Paludan, Jacob Giehm Mikkelsen, Takashi Fujita, Mette Christiansen, Rune Hartmann, Trine H Mogensen

Journal: J. Exp. Med.. 2015 Aug;212(9):1371-9.

 

Herpes simplex encephalitis (HSE) in children has previously been linked to defects in type I interferon (IFN) production downstream of Toll-like receptor 3. Here, we describe a novel genetic etiology of HSE by identifying a heterozygous loss-of-function mutation in the IFN regulatory ...

Last Updated: 25 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Herpes simplex encephalitis" returned 12 free, full-text review articles on human participants. First 3 results:

Psychiatric aspects of herpes simplex encephalitis, tick-borne encephalitis and herpes zoster encephalitis among immunocompetent patients.
 

Author(s): Magdalena Więdłocha, Piotr Marcinowicz, Bartłomiej Stańczykiewicz

Journal: Adv Clin Exp Med. ;24(2):361-71.

 

The psychopathological symptoms occurring in the course of diseases associated with infections are often initially isolated and non-characteristic, and may cause diagnostic difficulties. Moreover, such disorders tend to be less responsive to psychiatric management. Among possible ...

Last Updated: 1 May 2015

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Herpes simplex virus encephalitis in pregnancy - a case report and review of reported patients in the literature.
 

Author(s): Katherine C Dodd, Benedict D Michael, Besa Ziso, Bode Williams, Ray Borrow, Anita Krishnan, Tom Solomon

Journal:

 

Herpes simplex virus (HSV) encephalitis is the most common sporadic cause of encephalitis with significant morbidity and mortality that is drastically reduced by early antiviral treatment.

Last Updated: 19 Apr 2015

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Proteomics in immunity and herpes simplex encephalitis.
 

Author(s): Rebeca Pérez de Diego, Claire Mulvey, Jean-Laurent Casanova, Jasminka Godovac-Zimmermann

Journal: Expert Rev Proteomics. 2014 Feb;11(1):21-9.

 

The genetic theory of infectious diseases has proposed that susceptibility to life-threatening infectious diseases in childhood, occurring in the course of primary infection, results mostly from individually rare but collectively diverse single-gene variants. Recent evidence of an ...

Last Updated: 20 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.