Hereditary pancreatitis

Common Name(s)

Hereditary pancreatitis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hereditary pancreatitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hereditary pancreatitis" returned 47 free, full-text research articles on human participants. First 3 results:

Hereditary Pancreatitis Associated With the N29T Mutation of the PRSS1 Gene in a Brazilian Family: A Case-Control Study.
 

Author(s): Marcio Garrison Dytz, Julia Mendes de Melo, Olga de Castro Santos, Isabel Durso da Silva Santos, Melanie Rodacki, Flavia Lucia Conceição, Tania Maria Ortiga-Carvalho

Journal: Medicine (Baltimore). 2015 Sep;94(37):e1508.

 

Hereditary pancreatitis (HP) is an autosomal-dominant disease with incomplete penetrance manifesting as early-onset chronic relapsing pancreatitis. A mutation in the PRSS1 gene is present in greater than 70% of HP kindreds and leads to a gain-of-function characterized by the increased ...

Last Updated: 17 Sep 2015

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Long-term outcomes of total pancreatectomy and islet auto transplantation for hereditary/genetic pancreatitis.
 

Author(s): Srinath Chinnakotla, David M Radosevich, Ty B Dunn, Melena D Bellin, Martin L Freeman, Sarah J Schwarzenberg, A N Balamurugan, Josh Wilhelm, Barbara Bland, Selwyn M Vickers, Gregory J Beilman, David E R Sutherland, Timothy L Pruett

Journal: J. Am. Coll. Surg.. 2014 Apr;218(4):530-43.

 

Chronic pancreatitis is a debilitating disease resulting from many causes. The subset with hereditary/genetic pancreatitis (HGP) not only has chronic pain, but also an increased risk for pancreatic cancer. Long-term outcomes of total pancreatectomy (TP) and islet autogeneic transplantation ...

Last Updated: 24 Mar 2014

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The histopathology of PRSS1 hereditary pancreatitis.
 

Author(s): Aatur D Singhi, Reetesh K Pai, Jeffrey A Kant, Tanner L Bartholow, Herbert J Zeh, Kenneth K Lee, Martin Wijkstrom, Dhiraj Yadav, Rita Bottino, Randall E Brand, Jennifer S Chennat, Mark E Lowe, Georgios I Papachristou, Adam Slivka, David C Whitcomb, Abhinav Humar

Journal: Am. J. Surg. Pathol.. 2014 Mar;38(3):346-53.

 

Hereditary pancreatitis is an autosomal dominant disorder with 80% penetrance and variable expressivity. The vast majority of cases have been linked to mutations within the cationic trypsinogen gene, also referred to as serine protease 1 (PRSS1). Other than inheritance, PRSS1 pancreatitis ...

Last Updated: 14 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hereditary pancreatitis" returned 8 free, full-text review articles on human participants. First 3 results:

Hereditary chronic pancreatitis.
 

Author(s): Jonas Rosendahl, Hans Bödeker, Joachim Mössner, Niels Teich

Journal:

 

Hereditary chronic pancreatitis (HCP) is a very rare form of early onset chronic pancreatitis. With the exception of the young age at diagnosis and a slower progression, the clinical course, morphological features and laboratory findings of HCP do not differ from those of patients ...

Last Updated: 18 Jan 2007

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Biochemical models of hereditary pancreatitis.
 

Author(s): Miklós Sahin-Tóth

Journal: Endocrinol. Metab. Clin. North Am.. 2006 Jun;35(2):303-12, ix.

 

The past decade has witnessed remarkable progress in the genetics of chronic pancreatitis. Despite these accomplishments, the understanding of the molecular mechanisms through which PRSS1 and SPINK1 mutations cause chronic pancreatitis has remained sketchy. Pancreatitis-associated ...

Last Updated: 24 Apr 2006

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[Hereditary pancreatitis].
 

Author(s): Sung Koo Lee

Journal: Korean J Gastroenterol. 2005 Nov;46(5):358-67.

 

The first family of hereditary pancreatitis was described in 1952. The mode of inheritance is autosomal dominant trait with an 80% of penetrance rate. Although hereditary pancreatitis is rare, this disorder has provided valuable insights in understanding the pathophysiology of pancreatitis ...

Last Updated: 22 Nov 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.
 

Status: Recruiting

Condition Summary: Hereditary Pancreatitis; Hereditary Pancreatic Cancer

 

Last Updated: 2 Nov 2016

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Pancreatic Cancer Early Detection Program
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Pancreas Cancer; Pancreatic Adenocarcinoma; Familial Pancreatic Cancer; BRCA 1/2; HNPCC; Lynch Syndrome; Hereditary Pancreatitis; FAMMM; Familial Atypical Multiple Mole Melanoma; Peutz Jeghers Syndrome

 

Last Updated: 30 Jul 2014

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Pancreatic Cancer Screening of High-Risk Individuals in Arkansas
 

Status: Recruiting

Condition Summary: Pancreatic Neoplasms; Peutz-Jegher's Syndrome; BRCA1 Gene Mutation; BRCA2 Gene Mutation; Ataxia Telangiectasia; Familial Atypical Mole-Malignant Melanoma Syndrome; Colorectal Neoplasms, Hereditary Nonpolyposis; Hereditary Pancreatitis

 

Last Updated: 20 Jul 2016

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