Hepatitis E

Common Name(s)

Hepatitis E

Hepatitis E is a viral hepatitis that affects the liver and is caused by the hepatitis E virus, or HEV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. It stores vitamins, minerals and sugars. And it helps control cholesterol levels. Hepatitis E occurs when the hepatitis E virus causes the liver to swell, scar, and become inflamed, which stops it from working properly or completely Symptoms may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Hepatitis E symptoms usually go away after 4-6 weeks. It is rare for HEV to become chronic, but it can be very serious for pregnant women. HEV is spread through food or water that is contaminated with the feces (bowel movement) of people infected with HEV. There is some concern that it may also be passed through pigs in areas where HEV is common. There is no evidence that HEV is passed through sexual intercourse. It is very rarely passed from person to person. HEV is rare in developed nations. However, people who travel to the developing countries where HEV is common may be at risk. Outbreaks of hepatitis E have been reported in Central and South-East Asia, North and West Africa, and in Mexico, especially where fecal contamination of drinking water occurs. Physicians can diagnose hepatitis E through blood tests and stool tests that detect the presence of HEV. Physicians and hospitals can provide supportive care for individuals affected by HEV until they recover if needed. If HEV does become chronic, medications are available to help treat the condition. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis E" returned 805 free, full-text research articles on human participants. First 3 results:

Hepatitis E virus persists in the presence of a type III interferon response.
 

Author(s): Xin Yin, Xinlei Li, Charuta Ambardekar, Zhimin Hu, Sébastien Lhomme, Zongdi Feng

Journal:

 

The RIG-I-like RNA helicase (RLR)-mediated interferon (IFN) response plays a pivotal role in the hepatic antiviral immunity. The hepatitis A virus (HAV) and the hepatitis C virus (HCV) counter this response by encoding a viral protease that cleaves the mitochondria antiviral signaling ...

Last Updated: 30 May 2017

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Hepatitis E and blood donation safety in selected European countries: a shift to screening?
 

Author(s): Dragoslav Domanović, Richard Tedder, Johannes Blümel, Hans Zaaijer, Pierre Gallian, Christoph Niederhauser, Silvia Sauleda Oliveras, Joan O'Riordan, Fiona Boland, Lene Harritshøj, Maria São José Nascimento, Anna Rita Ciccaglione, Constatina Politis, Cornelia Adlhoch, Benoit Flan, Wahiba Oualikene-Gonin, Guy Rautmann, Paul Strengers, Patricia Hewitt

Journal: Euro Surveill.. 2017 Apr;22(16):.

 

The public health implications of hepatitis E virus (HEV) in Europe have changed due to increasing numbers of hepatitis E cases and recent reports of chronic, persistent HEV infections associated with progression to cirrhosis in immunosuppressed patients. The main infectious risk ...

Last Updated: 28 Apr 2017

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Clinical features of acute hepatitis E super-infections on chronic hepatitis B.
 

Author(s): Chong Chen, Shu-Ye Zhang, Dan-Dan Zhang, Xin-Yan Li, Yu-Ling Zhang, Wei-Xia Li, Jing-Jing Yan, Min Wang, Jing-Na Xun, Chuan Lu, Yun Ling, Yu-Xian Huang, Liang Chen

Journal: World J. Gastroenterol.. 2016 Dec;22(47):10388-10397.

 

To examine the clinical features and risk factors for adverse outcomes in chronic hepatitis B (CHB) superimposed with hepatitis E virus (HEV).

Last Updated: 6 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis E" returned 59 free, full-text review articles on human participants. First 3 results:

Hepatitis E infection among Ghanaians: a systematic review.
 

Author(s): Richard Ofori-Asenso, Akosua Adom Agyeman

Journal:

 

Hepatitis E virus (HEV) infection is considered to be of significant public health importance in many developing countries. In this review, we aim to summarise studies on HEV with the aim of providing a further understanding of the epidemiology of the disease in Ghana.

Last Updated: 6 Feb 2017

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Hepatitis E Virus in Industrialized Countries: The Silent Threat.
 

Author(s): Pilar Clemente-Casares, Carlota Ramos-Romero, Eugenio Ramirez-Gonzalez, Antonio Mas

Journal: Biomed Res Int. 2016 ;2016():9838041.

 

Hepatitis E virus (HEV) is the main cause of acute viral hepatitis worldwide. Its presence in developing countries has been documented for decades. Developed countries were supposed to be virus-free and initially only imported cases were detected in those areas. However, sporadic ...

Last Updated: 10 Jan 2017

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Hepatitis E: Discovery, global impact, control and cure.
 

Author(s): Mohammad S Khuroo, Mehnaaz S Khuroo, Naira S Khuroo

Journal: World J. Gastroenterol.. 2016 Aug;22(31):7030-45.

 

Hepatitis E was identified as an epidemic of non-A, non-B hepatitis from Kashmir, India in 1978. Hepatitis E virus (HEV), the etiological agent is the sole member of family Hepeviridae. The virus has marked heterogeneity and infects many animals like bats, camel, chicken, deer, boar, ...

Last Updated: 9 Sep 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 25 May 2017

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Seroprevalence of Hepatitis E in People With an Organ Transplant
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 30 Jun 2017

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Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh.
 

Status: Not yet recruiting

Condition Summary: Hepatitis E Infection

 

Last Updated: 29 Apr 2016

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