Hepatitis E

Common Name(s)

Hepatitis E

Hepatitis E is a liver disease caused by the Hepatitis E virus, transmitted mainly through contaminated drinking water. Hepatitis E is most prevalent in East and South Asia, though it is found worldwide. It is usually a self-limiting infection and resolves within 4-6 weeks, though sometimes it may develop into a suddenly severe form in which acute liver failure occurs. Common signs and symptoms of hepatitis include jaundice, loss of appetite, an enlarged, tender liver, abdominal pain and tenderness, nausea and vomiting, and fever.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis E" returned 671 free, full-text research articles on human participants. First 3 results:

Ribavirin for chronic hepatitis E virus infection.
 

Author(s): Nassim Kamar, Vincent Mallet, Jacques Izopet

Journal: N. Engl. J. Med.. 2014 Jun;370(25):2447-8.

 

Last Updated: 19 Jun 2014

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Prevalence of hepatitis B e antigen among human immunodeficiency virus and hepatitis B virus co-infected patients in Jos, Nigeria.
 

Author(s): Michael O Iroezindu, Comfort A Daniyam, Oche O Agbaji, Ejiji S Isa, Edith N Okeke, Godwin E Imade

Journal:

 

Human immunodeficiency virus (HIV) negatively impacts the natural history of hepatitis B virus (HBV) infection, including replication. We determined the prevalence of HBeAg in HIV/HBV co-infected patients compared to HBV mono-infected controls and further investigated the relationship ...

Last Updated: 16 Dec 2013

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Hepatitis E virus genotype 1 infection of swine kidney cells in vitro is inhibited at multiple levels.
 

Author(s): H T Nguyen, P Shukla, U Torian, K Faulk, S U Emerson

Journal: J. Virol.. 2014 Jan;88(2):868-77.

 

Genotype 1 hepatitis E viruses (HEVs) are restricted to primate hosts, whereas genotype 3 HEVs predominantly infect swine, in addition to primates. In order to identify possible determinants of the host range, infectious recombinant viruses and chimeras of a genotype 1 isolate and ...

Last Updated: 31 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis E" returned 34 free, full-text review articles on human participants. First 3 results:

Zoonotic transmission of hepatitis E virus in industrialized countries.
 

Author(s): Franco Maria Ruggeri, Ilaria Di Bartolo, Eleonora Ponterio, Giorgia Angeloni, Marcello Trevisani, Fabio Ostanello

Journal: New Microbiol.. 2013 Oct;36(4):331-44.

 

Hepatitis E is an infectious viral disease with clinical and morphological features of acute hepatitis. The disease represents an important public health problem in developing countries, where it is often related to outbreaks mainly associated with consumption of contaminated water. ...

Last Updated: 1 Nov 2013

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Hepatitis E virus: foodborne, waterborne and zoonotic transmission.
 

Author(s): Danielle M Yugo, Xiang-Jin Meng

Journal:

 

Hepatitis E virus (HEV) is responsible for epidemics and endemics of acute hepatitis in humans, mainly through waterborne, foodborne, and zoonotic transmission routes. HEV is a single-stranded, positive-sense RNA virus classified in the family Hepeviridae and encompasses four known ...

Last Updated: 27 Sep 2013

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[Hepatitis E].
 

Author(s): Gaetano Scotto, Fabio Bulla, Francesca Campanale, Alessandra Tartaglia, Vincenzina Fazio

Journal: Infez Med. 2013 Sep;21(3):175-88.

 

Hepatitis E virus (HEV) represents the main aetiological agent of enteric non-A hepatitis and is the only member of a new virus, Hepevirus, belonging to the family of Hepeviridae. HEV is the single most important cause of acute clinical hepatitis among adults in many areas of the ...

Last Updated: 6 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Seroprevalence of Hepatitis E in People With an Organ Transplant
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 29 Jul 2014

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Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®)
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 10 Jul 2014

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A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus
 

Status: Recruiting

Condition Summary: Acute on Chronic Hepatic Failure; Liver Failure; Hepatitis E Infection

 

Last Updated: 29 Sep 2012

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