Hepatitis E

Common Name(s)

Hepatitis E

Hepatitis E is a viral hepatitis that affects the liver and is caused by the hepatitis E virus, or HEV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. It stores vitamins, minerals and sugars. And it helps control cholesterol levels. Hepatitis E occurs when the hepatitis E virus causes the liver to swell, scar, and become inflamed, which stops it from working properly or completely Symptoms may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Hepatitis E symptoms usually go away after 4-6 weeks. It is rare for HEV to become chronic, but it can be very serious for pregnant women. HEV is spread through food or water that is contaminated with the feces (bowel movement) of people infected with HEV. There is some concern that it may also be passed through pigs in areas where HEV is common. There is no evidence that HEV is passed through sexual intercourse. It is very rarely passed from person to person. HEV is rare in developed nations. However, people who travel to the developing countries where HEV is common may be at risk. Outbreaks of hepatitis E have been reported in Central and South-East Asia, North and West Africa, and in Mexico, especially where fecal contamination of drinking water occurs. Physicians can diagnose hepatitis E through blood tests and stool tests that detect the presence of HEV. Physicians and hospitals can provide supportive care for individuals affected by HEV until they recover if needed. If HEV does become chronic, medications are available to help treat the condition. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis E" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis E" returned 798 free, full-text research articles on human participants. First 3 results:

Chronic Hepatitis E Infection in a Persistently Immunosuppressed Patient Unable to Be Eliminated after Ribavirin Therapy.
 

Author(s): Masato Miyoshi, Sei Kakinuma, Yoko Tanabe, Koji Ishii, Tian-Cheng Li, Takaji Wakita, Yukio Tsuura, Hideki Watanabe, Yasuhiro Asahina, Mamoru Watanabe, Takaaki Ikeda

Journal: Intern. Med.. ;55(19):2811-2817.

 

Recent case reports have shown that hepatitis E virus (HEV) infection can cause chronic hepatitis in immunosuppressed or immunocompromised patients. A 37-year-old woman suffered from prolonged elevation of aminotransferases after chemotherapy for Burkitt's lymphoma and was diagnosed ...

Last Updated: 11 Oct 2016

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A Case Report About the Most Common Yet Most Forgotten Hepatitis E.
 

Author(s): Madhuri Chandnani, Mandeep Kaur, Anusha Ramadhas, Taisiya Tumarinson

Journal:

 

BACKGROUND Hepatitis E virus (HEV) is the most common cause of enterically acquired acute viral hepatitis worldwide with major prevalence in the developing countries. An increasing number of sporadic cases of acute HEV infection have also been found in developed countries, but there ...

Last Updated: 16 Aug 2016

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Hepatitis E virus infection--a new threat for Europe.
 

Author(s): Tadeusz Wojciech Łapiński, Jerzy Jaroszewicz

Journal: Przegl Epidemiol. 2016 ;70(1):11-4, 103-6.

 

Of 20 million of patients infected with hepatitis E virus (HEV) worldwide 57 thousand dies each year. HEV-infection is not longer regarded as a diseases in developing endemic countries of Asia, Africa and Latin America. The majority of European countries faces increasing number of ...

Last Updated: 27 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis E" returned 59 free, full-text review articles on human participants. First 3 results:

Hepatitis E infection among Ghanaians: a systematic review.
 

Author(s): Richard Ofori-Asenso, Akosua Adom Agyeman

Journal:

 

Hepatitis E virus (HEV) infection is considered to be of significant public health importance in many developing countries. In this review, we aim to summarise studies on HEV with the aim of providing a further understanding of the epidemiology of the disease in Ghana.

Last Updated: 6 Feb 2017

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Hepatitis E Virus in Industrialized Countries: The Silent Threat.
 

Author(s): Pilar Clemente-Casares, Carlota Ramos-Romero, Eugenio Ramirez-Gonzalez, Antonio Mas

Journal: Biomed Res Int. 2016 ;2016():9838041.

 

Hepatitis E virus (HEV) is the main cause of acute viral hepatitis worldwide. Its presence in developing countries has been documented for decades. Developed countries were supposed to be virus-free and initially only imported cases were detected in those areas. However, sporadic ...

Last Updated: 10 Jan 2017

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Hepatitis E Virus Mutations: Functional and Clinical Relevance.
 

Author(s): Hoang van Tong, Nghiem Xuan Hoan, Bo Wang, Heiner Wedemeyer, C-Thomas Bock, Thirumalaisamy P Velavan

Journal: EBioMedicine. 2016 Sep;11():31-42.

 

Hepatitis E virus (HEV) infection is a major cause of acute hepatitis and affects more than 20 million individuals, with three million symptomatic cases and 56,000 recognized HEV-related deaths worldwide. HEV is endemic in developing countries and is gaining importance in developed ...

Last Updated: 16 Aug 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Seroprevalence of Hepatitis E in People With an Organ Transplant
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 24 Jan 2017

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Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh.
 

Status: Not yet recruiting

Condition Summary: Hepatitis E Infection

 

Last Updated: 29 Apr 2016

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Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection.
 

Status: Recruiting

Condition Summary: Hepatitis E

 

Last Updated: 24 Feb 2016

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