Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a medical condition which affects the liver. The liver is an organ found in the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. It stores vitamins, minerals and sugars. And it helps control cholesterol levels. Hepatitis occurs when the liver swells, scars, and becomes inflamed, which stops it from working properly or completely. It can occur with little or no symptoms, but will often lead to jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. Sometimes hepatitis can heal on its own, but other times it will progress to fibrosis (scarring) and cirrhosis. Hepatitis is chronic if it lasts more than six months. The most common causes of hepatitis are viral infections, but other medical conditions, including autoimmune disorders, certain medications and toxic substances, including alcohol and drugs, can also cause hepatitis. Viral hepatitis includes Hepatitis A, B, C, D and E. There are vaccines available to help prevent types A and B. Hepatitis A and E usually resolve on their own, whereas hepatitis B, C, and D can be chronic and serious. Transmission is dependent on the virus type. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy. Treatment for hepatitis is usually supportive, preventing further damage by avoiding toxic medications (including acetaminophen or Tylenol), drugs or alcohol, and, if possible, reversing the underlying cause. There are medications available to treat chronic hepatitis and, due to medical research, treatments are improving rapidly. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 16 Mar 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 16 Mar 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 18189 free, full-text research articles on human participants. First 3 results:

Clinical study on treatment of chronic viral cholestatic hepatitis with chishaodanpi decoction.
 

Author(s): Heping Zhao, Tianqing Hou, Dandan Shao

Journal: J Tradit Chin Med. 2014 Dec;34(6):646-51.

 

To observe the therapeutic effect of Chishaodanpi decoction (CSDPD) on chronic viral cholestatic hepatitis.

Last Updated: 26 Jan 2015

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Demographics, clinical characteristics, IFNL3- and IFNL4- polymorphisms in a cohort of hepatitis C patients from Puerto Rico.
 

Author(s): Lilliana Morales-Vásquez, Edgar I Miranda-Avalo, José R Rodríguez-Medina, Yomarid Quiñones-Badillo, Juan Marqués-Lespier, José Muñoz-Acabá, Rafael Pastrana, Cynthia M Pérez-Cardona, Yasuhiro Yamamura, Esther A Torres

Journal: P R Health Sci J. 2014 Dec;33(4):177-83.

 

To describe the risk factors for infection, complications, treatment received and response in Puerto Ricans with HCV attending gastroenterology clinics at UPR-MSC, and the prevalence of single nucleotide polymorphisms (SNPs) in IFNL3 and IFNL4 in this population.

Last Updated: 7 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 1747 free, full-text review articles on human participants. First 3 results:

Reducing the neglected burden of viral hepatitis in Africa: strategies for a global approach.
 

Author(s): Maud Lemoine, Serge Eholié, Karine Lacombe

Journal: J. Hepatol.. 2015 Feb;62(2):469-76.

 

The burden of liver disease may dramatically increase in the near future in Africa, where screening and access to care and treatment are hampered by inadequate disease surveillance, lack of high-quality tools to assess chronic liver disease, and underestimated needs for human and ...

Last Updated: 19 Jan 2015

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The emerging role of hepatitis B virus pre-S2 deletion mutant proteins in HBV tumorigenesis.
 

Author(s): Ih-Jen Su, Lily Hui-Ching Wang, Wen-Chuan Hsieh, Han-Chieh Wu, Chiao-Fang Teng, Hung-Wen Tsai, Wenya Huang

Journal:

 

Chronic hepatitis B virus (HBV) infection can cause hepatocellular carcinoma (HCC). Several hypotheses have been proposed to explain the mechanisms of HBV tumorigenesis, including inflammation and liver regeneration associated with cytotoxic immune injuries and transcriptional activators ...

Last Updated: 17 Oct 2014

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Molecular diagnostics in the management of chronic hepatitis C: key considerations in the era of new antiviral therapies.
 

Author(s): Bryan Cobb, Gabrielle Heilek, Regis A Vilchez

Journal: BMC Infect. Dis.. 2014 ;14 Suppl 5():S8.

 

Molecular tests that detect and/or quantify HCV RNA are important in the diagnosis and management of patients with chronic hepatitis C (CHC) undergoing anti-viral therapy. The primary goal of anti-HCV therapy is to achieve a sustained virologic response (SVR) defined as "undetectable" ...

Last Updated: 19 Sep 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis C; Hepatitis B; Autoimmune Hepatitis; Liver Cirrhosis, Biliary; Cholangitis, Sclerosing

 

Last Updated: 29 Nov 2005

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Non-invasive Biomarkers of Fibrosis in Pediatric Viral Hepatitis
 

Status: Recruiting

Condition Summary: Viral Hepatitis; Liver Fibrosis; Liver Disease; Hepatitis B; Hepatitis C

 

Last Updated: 23 Mar 2015

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New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C
 

Status: Recruiting

Condition Summary: Cirrhosis; Chronic Hepatitis C; Hepatitis C; Hepatitis C, Chronic

 

Last Updated: 26 Feb 2015

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