Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a medical condition that affects the liver. The liver is an organ found in the right side of our belly (abdomen) under the rib cage. The liver cleans our blood of toxins, poisons, and bacteria; produces bile that helps our body breakdown food; stores vitamins, minerals and sugars; and helps control cholesterol levels. Hepatitis occurs when the liver swells, scars, and becomes inflamed, which stops it from working properly or completely.

Symptoms of hepatitis may include jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. Sometimes hepatitis can heal on its own, but other times it will progress to fibrosis and cirrhosis (types of scarring).

The most common causes of hepatitis are viral infections, but other medical conditions, including autoimmune disorders, certain medications and toxic substances, including alcohol and drugs, can also cause hepatitis. Viral hepatitis includes Hepatitis A, B, C, D and E. There are vaccines available to help prevent types A and B. Hepatitis A and E usually resolve on their own, whereas hepatitis B, C, and D can be chronic and serious. Transmission is dependent on the virus type. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy.

Treatment for hepatitis is usually supportive, preventing further damage by avoiding toxic medications (including acetaminophen or Tylenol), drugs or alcohol, and, if possible, reversing the underlying cause. There are medications available to treat chronic hepatitis and, due to medical research, treatments are improving rapidly. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 21892 free, full-text research articles on human participants. First 3 results:

Epidemiological characteristics and clinical manifestations of hepatitis E virus infection in Bulgaria: A report on 20 patients.
 

Author(s): Magdalena Baymakova, Benjamin Sakem, Kamen Plochev, Georgi T Popov, Raynichka Mihaylova-Garnizova, Valentina Kovaleva, Todor Kundurdjiev

Journal: Srp Arh Celok Lek. ;144(1-2):63-8.

 

Hepatitis E is one of the leading clinical manifestations of acute viral hepatitis in developing countries. In industrialized countries, during the past several years, sporadic "autochthonous" cases of HEV infection have been increased.

Last Updated: 9 Jun 2016

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IMPACT OF THE PEGYLATED-INTERFERON AND RIBAVIRIN THERAPY ON THE TREATMENT-RELATED MORTALITY OF PATIENTS WITH CIRRHOSIS DUE TO HEPATITIS C VIRUS.
 

Author(s): Kelly Fernanda Nomura Dresch, Angelo Alves de Mattos, Cristiane Valle Tovo, Fernanda Quadros de Onofrio, Leandro Casagrande, Alberi Adolfo Feltrin, Iago Christofoli de Barros, Paulo Roberto Lerias de Almeida

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2016 ;58():37.

 

Although the protease inhibitors have revolutionized the therapy of chronic hepatitis C (CHC), the concomitant use of pegylated-interferon (PEG-IFN) and ribavirin (RBV) is associated to a high rate of adverse effects. In this study, we evaluated the consequences of PEG-IFN and RBV ...

Last Updated: 3 Jun 2016

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Prevention of Perinatal Transmission of Hepatitis B Virus: Assessment Among Wisconsin Maternity Hospitals.
 

Author(s): Stephanie M Borchardt, Anna Kocharian, Daniel Hopfensperger, Jeffrey P Davis

Journal: WMJ. 2016 Apr;115(2):74-9; quiz 80.

 

To evaluate the completeness of identification of pregnant women testing positive for hepatitis B surface antigen (HBsAg) and birth dose hepatitis B vaccine administration, and the extent of appropriate prophylaxis of infants born to women with and without maternal HBsAg status documented ...

Last Updated: 20 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 2362 free, full-text review articles on human participants. First 3 results:

[Consequences of extrahepatic manifestations of hepatitis C viral infection (HCV)].
 

Author(s): Agnieszka Pawełczyk

Journal:

 

The hepatitis C virus (HCV) is a primarily hepatotropic virus. However, numerous extrahepatic symptoms are observed in patients chronically infected with HCV, e.g. cryoglobulinemia, lymphoproliferative disorders, kidney diseases, disturbances of the central and peripheral nervous ...

Last Updated: 27 Apr 2016

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[Nontraumatic causes of bilateral avascular necrosis of the femoral head: link between hepatitis C and pegylated interferon].
 

Author(s): J G Gómez-Mont Landerreche, F Gil-Orbezo, H Morales-Dominguez, M Navarrete-Álvarez, C Trueba-Davalillo, P Capuano-Tripp

Journal: Acta Ortop Mex. ;29(3):172-5.

 

Avascular necrosis of the femoral head is a frequent condition in patients with a history of trauma. The major pathologic causes include vascular diseases, malignancies, hypercoagulability states, long-term steroid treatment, and some patients have a history of hepatitis C infection ...

Last Updated: 22 Mar 2016

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Systematic Review and Network Meta-Analysis of Randomized Controlled Trials: Comparative Effectiveness and Safety of Direct-Acting Antiviral Agents for Treatment-Naive Hepatitis C Genotype 1.
 

Author(s): Gui-Qi Zhu, Zhuo-Lin Zou, Ji-Na Zheng, Da-Zhi Chen, Tian-Tian Zou, Ke-Qing Shi, Ming-Hua Zheng

Journal: Medicine (Baltimore). 2016 Mar;95(9):e3004.

 

All possible direct-acting antiviral agent (DAA) regimens for treatment-naive hepatitis C genotype 1 were evaluated by many randomized controlled trials (RCTs). However, the optimum regimen remains inconclusive. We aim to compare interventions in terms of sustained virological response ...

Last Updated: 6 Mar 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection
 

Status: Recruiting

Condition Summary: Hepatitis B; Chronic Hepatitis B; Hepatitis B, Chronic; Hepatitis B Infection; HBV

 

Last Updated: 6 Jul 2016

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Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis C; Hepatitis B; Autoimmune Hepatitis; Liver Cirrhosis, Biliary; Cholangitis, Sclerosing

 

Last Updated: 29 Nov 2005

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Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Delta
 

Status: Recruiting

Condition Summary: Chronic Hepatitis B; Chronic Hepatitis D

 

Last Updated: 24 May 2006

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