Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a medical condition that affects the liver. The liver is an organ found in the right side of our belly (abdomen) under the rib cage. The liver cleans our blood of toxins, poisons, and bacteria; produces bile that helps our body breakdown food; stores vitamins, minerals and sugars; and helps control cholesterol levels. Hepatitis occurs when the liver swells, scars, and becomes inflamed, which stops it from working properly or completely.

Symptoms of hepatitis may include jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. Sometimes hepatitis can heal on its own, but other times it will progress to fibrosis and cirrhosis (types of scarring).

The most common causes of hepatitis are viral infections, but other medical conditions, including autoimmune disorders, certain medications and toxic substances, including alcohol and drugs, can also cause hepatitis. Viral hepatitis includes Hepatitis A, B, C, D and E. There are vaccines available to help prevent types A and B. Hepatitis A and E usually resolve on their own, whereas hepatitis B, C, and D can be chronic and serious. Transmission is dependent on the virus type. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy.

Treatment for hepatitis is usually supportive, preventing further damage by avoiding toxic medications (including acetaminophen or Tylenol), drugs or alcohol, and, if possible, reversing the underlying cause. There are medications available to treat chronic hepatitis and, due to medical research, treatments are improving rapidly. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 27 Apr 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 27 Apr 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 18518 free, full-text research articles on human participants. First 3 results:

Prednisolone or pentoxifylline for alcoholic hepatitis.
 

Author(s): Mark R Thursz, Paul Richardson, Michael Allison, Andrew Austin, Megan Bowers, Christopher P Day, Nichola Downs, Dermot Gleeson, Alastair MacGilchrist, Allister Grant, Steven Hood, Steven Masson, Anne McCune, Jane Mellor, John O'Grady, David Patch, Ian Ratcliffe, Paul Roderick, Louise Stanton, Nikhil Vergis, Mark Wright, Stephen Ryder, Ewan H Forrest,

Journal: N. Engl. J. Med.. 2015 Apr;372(17):1619-28.

 

Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver impairment that occurs in patients with a history of heavy and prolonged alcohol use. The short-term mortality among patients with severe disease exceeds 30%. Prednisolone and pentoxifylline are both recommended ...

Last Updated: 23 Apr 2015

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Occult hepatitis C virus infection in dialysis patients: does it need special attention?
 

Author(s): Mohammad Saeid Rezaee-Zavareh, Mahdi Ramezani-Binabaj, Behzad Einollahi

Journal: Saudi J Kidney Dis Transpl. 2015 Mar;26(2):368-9.

 

Last Updated: 12 Mar 2015

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Hepatitis A virus in a medical setting in Madagascar: a lesson for public health.
 

Author(s): Massimo Ciccozzi, Eleonora Cella, Marta Giovanetti, Alessandra Lo Presti, Anna Rita Ciccaglione, Isabella Bon, Paolo Gallo, Maria Musumeci, Mario Bonetti, Antonio Picardi, Elisabetta Riva, Giovanni Mottini

Journal: New Microbiol.. 2015 Jan;38(1):119-20.

 

Last Updated: 6 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 1879 free, full-text review articles on human participants. First 3 results:

Reducing the neglected burden of viral hepatitis in Africa: strategies for a global approach.
 

Author(s): Maud Lemoine, Serge Eholié, Karine Lacombe

Journal: J. Hepatol.. 2015 Feb;62(2):469-76.

 

The burden of liver disease may dramatically increase in the near future in Africa, where screening and access to care and treatment are hampered by inadequate disease surveillance, lack of high-quality tools to assess chronic liver disease, and underestimated needs for human and ...

Last Updated: 19 Jan 2015

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[Chronic viral hepatitis B and C in immigrant population, Spain].
 

Author(s): Enrique Calderón Sandubete, Rosa Yang Lai, María Luz Calero Bernal, María Teresa Martínez Rísquez, María Calderón Baturone, Carmen de la Horra Padilla

Journal: Rev. Esp. Salud Publica. ;88(6):811-8.

 

the prevalence of chronic viral hepatitis in Spain could vary because of the immigrants coming from countries having an elevated with a higher endemicity of hepatitis B and C virus. Hepatitis B and hepatitis C virus infections are an important health problem worldwide taking into ...

Last Updated: 24 Nov 2014

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[Hepatitis B virus reactivation induced by Brentuximab vedotin in the treatment of Hodgkin lymphoma: a case report and literature review].
 

Author(s): Hui Yang, Zhigang Cao, Zhihong Wang, Mo Liu, Hongwei Zhou, Qingming Yang

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Oct;35(10):949-50.

 

Last Updated: 23 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Non-invasive Biomarkers of Fibrosis in Pediatric Viral Hepatitis
 

Status: Recruiting

Condition Summary: Viral Hepatitis; Liver Fibrosis; Liver Disease; Hepatitis B; Hepatitis C

 

Last Updated: 23 Mar 2015

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Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis C; Hepatitis B; Autoimmune Hepatitis; Liver Cirrhosis, Biliary; Cholangitis, Sclerosing

 

Last Updated: 29 Nov 2005

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New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C
 

Status: Recruiting

Condition Summary: Cirrhosis; Chronic Hepatitis C; Hepatitis C; Hepatitis C, Chronic

 

Last Updated: 30 Apr 2015

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