Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a rare genetic condition that affects the liver and results from a mutation or error in a person’s DNA or genes. The liver is an organ in your abdomen (belly) which is responsible for breaking down certain chemicals and compounds found throughout the body as well as for producing bile, which is a solution that helps the body digest fat. Hepatitis occurs when the liver swells, scars, and becomes inflamed, causing it to malfunction or stop functioning altogether. It can occur with little or no symptoms, but will often lead to jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. The most common causes of hepatitis are viral infections, but other conditions and toxic substances, including alcohol and drugs, can also cause hepatitis. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy. Treatment for hepatitis is usually supportive, avoiding additional damage with toxic medications or alcohol, and, if possible, reversing the underlying cause. Longterm management may include medications to fight infections and avoiding alcohol, tylenol and other substances that can further damage the liver.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 5 May 2014

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Logo
American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 5 May 2014

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 17587 free, full-text research articles on human participants. First 3 results:

More on hepatitis B virus rtI233V mutation and resistance to adefovir.
 

Author(s): Andreas Geipel, Dieter Glebe, Wolfram H Gerlich

Journal: N. Engl. J. Med.. 2014 Jul;371(5):483.

 

Last Updated: 31 Jul 2014

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Payers consider waiting out budget-busting hepatitis C drug.
 

Author(s): John Carroll

Journal: Manag Care. 2014 May;23(5):7, 9.

 

Last Updated: 14 Jul 2014

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Ribavirin for chronic hepatitis E virus infection.
 

Author(s): Nassim Kamar, Vincent Mallet, Jacques Izopet

Journal: N. Engl. J. Med.. 2014 Jun;370(25):2447-8.

 

Last Updated: 19 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 1700 free, full-text review articles on human participants. First 3 results:

Antiviral treatment of hepatitis C.
 

Author(s): Eoin R Feeney, Raymond T Chung

Journal:

 

Hepatitis C virus (HCV) infection is a substantial health problem worldwide. Most patients infected with HCV remain chronically infected, with an increased risk of cirrhosis and hepatocellular carcinoma. Although they are associated with toxicities and low sustained viral response ...

Last Updated: 8 Jul 2014

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Development, production, and postmarketing surveillance of hepatitis A vaccines in China.
 

Author(s): Fuqiang Cui, Xiaofeng Liang, Fuzhen Wang, Hui Zheng, Yvan J Hutin, Weizhong Yang

Journal: J Epidemiol. 2014 ;24(3):169-77.

 

China has long experience using live attenuated and inactivated vaccines against hepatitis A virus (HAV) infection. We summarize this experience and provide recent data on adverse events after immunization (AEFIs) with hepatitis A vaccines in China. We reviewed the published literature ...

Last Updated: 8 May 2014

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An update on hepatitis B, D, and E viruses.
 

Author(s): Jennifer Price

Journal: Top Antivir Med. 2014 Jan;21(5):157-63.

 

Although newer and more effective treatments are now available for hepatitis C virus (HCV) infection, non-HCV viral hepatitis remains an important cause of liver disease, especially among HIV-infected individuals. Hepatitis B virus (HBV) is the leading cause of cirrhosis worldwide, ...

Last Updated: 17 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Non-invasive Biomarkers of Fibrosis in Pediatric Viral Hepatitis
 

Status: Recruiting

Condition Summary: Viral Hepatitis; Liver Fibrosis; Liver Disease; Hepatitis B; Hepatitis C

 

Last Updated: 11 Jun 2014

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Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis C; Hepatitis B; Autoimmune Hepatitis; Liver Cirrhosis, Biliary; Cholangitis, Sclerosing

 

Last Updated: 29 Nov 2005

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Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C/Hepatitis B Co-Infection and Chronic Hepatitis C
 

Status: Recruiting

Condition Summary: Hepatitis B, Chronic; Hepatitis C, Chronic

 

Last Updated: 10 Aug 2007

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