Hepatitis

Common Name(s)

Hepatitis

Hepatitis is a medical condition that affects the liver. The liver is an organ found in the right side of our belly (abdomen) under the rib cage. The liver cleans our blood of toxins, poisons, and bacteria; produces bile that helps our body breakdown food; stores vitamins, minerals and sugars; and helps control cholesterol levels. Hepatitis occurs when the liver swells, scars, and becomes inflamed, which stops it from working properly or completely.

Symptoms of hepatitis may include jaundice (yellowing of the skin), poor appetite, abdominal pain, enlargement of the abdomen, and a general feeling of being unwell, or malaise. Sometimes hepatitis can heal on its own, but other times it will progress to fibrosis and cirrhosis (types of scarring).

The most common causes of hepatitis are viral infections, but other medical conditions, including autoimmune disorders, certain medications and toxic substances, including alcohol and drugs, can also cause hepatitis. Viral hepatitis includes Hepatitis A, B, C, D and E. There are vaccines available to help prevent types A and B. Hepatitis A and E usually resolve on their own, whereas hepatitis B, C, and D can be chronic and serious. Transmission is dependent on the virus type. Physicians diagnose hepatitis by assessing symptoms during a physical exam, blood tests, and, if needed, using a liver biopsy.

Treatment for hepatitis is usually supportive, preventing further damage by avoiding toxic medications (including acetaminophen or Tylenol), drugs or alcohol, and, if possible, reversing the underlying cause. There are medications available to treat chronic hepatitis and, due to medical research, treatments are improving rapidly. Talk with your doctor if you or a family member has been diagnosed with hepatitis to decide on the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis" returned 21393 free, full-text research articles on human participants. First 3 results:

Sequential Therapy with PEG-IFN alpha-2a and Tenofovir in a Hepatitis B Virus-Infected African Man.
 

Author(s): Francesca Cainelli, Sandro Vento

Journal: Isr. Med. Assoc. J.. 2015 Dec;17(12):790.

 

Last Updated: 22 Feb 2016

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Treatment of chronic hepatitis B patients with tyrosine-methionine-aspartate-aspartate mutations.
 

Author(s): Aylin Calica Utku, Oguz Karabay

Journal: World J. Gastroenterol.. 2016 Jan;22(4):1727-8.

 

Lamivudine is an antiviral used for the treatment of chronic hepatitis B. Several studies have reported various mutations that are induced by lamivudine therapy. These mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif are necessary and sufficient to confer high-level ...

Last Updated: 28 Jan 2016

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Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator.
 

Author(s): Tri M Bui-Nguyen, Suresh B Pakala, Divijendranatha Reddy Sirigiri, Emil Martin, Ferid Murad, Suresh K Rayala, Rakesh Kumar, Rajesh Kumar

Journal: J. Biol. Chem.. 2016 Jan;291(3):1198.

 

Last Updated: 16 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis" returned 2306 free, full-text review articles on human participants. First 3 results:

[Nontraumatic causes of bilateral avascular necrosis of the femoral head: link between hepatitis C and pegylated interferon].
 

Author(s): J G Gómez-Mont Landerreche, F Gil-Orbezo, H Morales-Dominguez, M Navarrete-Álvarez, C Trueba-Davalillo, P Capuano-Tripp

Journal: Acta Ortop Mex. ;29(3):172-5.

 

Avascular necrosis of the femoral head is a frequent condition in patients with a history of trauma. The major pathologic causes include vascular diseases, malignancies, hypercoagulability states, long-term steroid treatment, and some patients have a history of hepatitis C infection ...

Last Updated: 22 Mar 2016

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A Brief Clinical Update on Hepatitis C--The Essentials.
 

Author(s): Jonas Lee, James Conniff, Connie Kraus, Sarina Schrager

Journal: WMJ. 2015 Dec;114(6):263-9; quiz 270.

 

Infection with the hepatitis C virus (HCV) is a common cause of cirrhosis and liver failure and the most common indication for liver transplant in the United States. Based on the prevalence of HCV infection at 1.3% of the US population, there are an estimated 74,000 people living ...

Last Updated: 8 Feb 2016

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Hepatitis C Virus in Children: Deferring Treatment in Expectation of Direct-Acting Antiviral Agents.
 

Author(s): Esther Granot, Etienne M Sokal

Journal: Isr. Med. Assoc. J.. 2015 Nov;17(11):707-11.

 

The major route of hepatitis C virus (HCV) infection in the pediatric age group is vertical, with infection occurring in up to 5% of infants born to mothers positive for HCV-RNA. The natural course of pediatric HCV infection is characterized by a high rate of spontaneous clearance, ...

Last Updated: 13 Jan 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
 

Status: Recruiting

Condition Summary: Hepatitis C; Hepatitis B; Autoimmune Hepatitis; Liver Cirrhosis, Biliary; Cholangitis, Sclerosing

 

Last Updated: 29 Nov 2005

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A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Japanese Adults With Chronic Hepatitis C Virus Infection
 

Status: Recruiting

Condition Summary: Chronic Hepatitis C Virus; Hepatitis C Virus

 

Last Updated: 27 Apr 2016

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A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Japanese Adults With Genotype 2 Chronic Hepatitis C Virus Infection
 

Status: Recruiting

Condition Summary: Chronic Hepatitis C Virus; Hepatitis C Virus

 

Last Updated: 4 May 2016

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