Hepatic fibrosis

Common Name(s)

Hepatic fibrosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatic fibrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatic fibrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatic fibrosis" returned 308 free, full-text research articles on human participants. First 3 results:

Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.
 

Author(s): Hikari Okada, Masao Honda, Jean S Campbell, Kai Takegoshi, Yoshio Sakai, Taro Yamashita, Takayoshi Shirasaki, Riuta Takabatake, Mikiko Nakamura, Takuji Tanaka, Shuichi Kaneko

Journal: Cancer Sci.. 2015 Sep;106(9):1143-52.

 

Differentially regulated microRNA (miRNA) are associated with hepatic fibrosis; however, their potential usefulness for blocking hepatic fibrosis has not been exploited fully. We examined the expression of miRNA in the liver of a transgenic mouse model in which platelet-derived growth ...

Last Updated: 23 Sep 2015

Go To URL
Non-alcoholic fatty liver disease (NAFLD) and significant hepatic fibrosis defined by non-invasive assessment in patients with type 2 diabetes.
 

Author(s): Abhasnee Sobhonslidsuk, Akharawit Pulsombat, Piyaporn Kaewdoung, Supanna Petraksa

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(5):1789-94.

 

Non-alcoholic fatty liver disease (NAFLD), the most common liver problem in diabetes, is a risk factor for liver cancer. Diabetes, high body mass index (BMI) and old age can all contribute to NAFLD progression. Transient elastography (TE) is used for non-invasive fibrosis assessment.

Last Updated: 16 Mar 2015

Go To URL
Serum osteopontin predicts degree of hepatic fibrosis and serves as a biomarker in patients with hepatitis C virus infection.
 

Author(s): Yasuhiro Matsue, Mikihiro Tsutsumi, Nobuhiko Hayashi, Takashi Saito, Mutsumi Tsuchishima, Nobuyuki Toshikuni, Tomiyasu Arisawa, Joseph George

Journal:

 

Osteopontin (OPN) is a matricellular protein that upregulates during pathogenesis of hepatic fibrosis. The present study was aimed to evaluate whether serum OPN could be used as a biomarker to assess the degree of hepatic fibrosis in patients with hepatitis C virus (HCV) infection.

Last Updated: 12 Mar 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatic fibrosis" returned 48 free, full-text review articles on human participants. First 3 results:

New gene therapy strategies for hepatic fibrosis.
 

Author(s): Adriana M Salazar-Montes, Luis D Hernández-Ortega, Martha S Lucano-Landeros, Juan Armendariz-Borunda

Journal: World J. Gastroenterol.. 2015 Apr;21(13):3813-25.

 

The liver is the largest internal organ of the body, which may suffer acute or chronic injury induced by many factors, leading to cirrhosis and hepatocarcinoma. Cirrhosis is the irreversible end result of fibrous scarring and hepatocellular regeneration, characterized by diffuse disorganization ...

Last Updated: 8 Apr 2015

Go To URL
Review of diagnostic techniques of hepatic fibrosis.
 

Author(s): Sobia Hassan, Serajuddaula Syed, Shahnaz Imdad Kehar

Journal: J Pak Med Assoc. 2014 Aug;64(8):941-5.

 

With increasing innovations aimed at the treatment of chronic liver disease (CLD), the precise staging of liver fibrosis is important to help establish efficacious management of disease activity in each patient. The development of biomarkers capable of non-invasive staging of fibrosis ...

Last Updated: 25 Sep 2014

Go To URL
Autophagy in hepatic fibrosis.
 

Author(s): Yang Song, Yingying Zhao, Fei Wang, Lichan Tao, Junjie Xiao, Changqing Yang

Journal: Biomed Res Int. 2014 ;2014():436242.

 

Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular ...

Last Updated: 29 Apr 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Development of an Imaging Biomarker for Hepatic Fibrosis Using Gadoxetate Disodium
 

Status: Recruiting

Condition Summary: Hepatic Fibrosis

 

Last Updated: 31 Jan 2013

Go to URL
Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLD
 

Status: Recruiting

Condition Summary: Chronic Hepatitis B; Hepatic Fibrosis; Fatty Liver

 

Last Updated: 1 Dec 2015

Go to URL
Shear Wave Sonoelastography in Pediatric Liver Fibrosis
 

Status: Recruiting

Condition Summary: Sonoelastography; Elastography; Elastograms; Liver Fibrosis; Hepatic Fibrosis; Cirrhosis; Pediatrics

 

Last Updated: 9 Dec 2015

Go to URL