Hepatic fibrosis

Common Name(s)

Hepatic fibrosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatic fibrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatic fibrosis" returned 357 free, full-text research articles on human participants. First 3 results:

Human neutrophil peptide-1 promotes alcohol-induced hepatic fibrosis and hepatocyte apoptosis.
 

Author(s): Rie Ibusuki, Hirofumi Uto, Kohei Oda, Akihiko Ohshige, Kazuaki Tabu, Seiichi Mawatari, Kotaro Kumagai, Shuji Kanmura, Tsutomu Tamai, Akihiro Moriuchi, Hirohito Tsubouchi, Akio Ido

Journal:

 

Neutrophil infiltration of the liver is a typical feature of alcoholic liver injury. Human neutrophil peptide (HNP)-1 is an antimicrobial peptide secreted by neutrophils. The aim of this study was to determine if HNP-1 affects ethanol-induced liver injury and to examine the mechanism ...

Last Updated: 13 Apr 2017

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Carvedilol Attenuates the Progression of Hepatic Fibrosis Induced by Bile Duct Ligation.
 

Author(s): Xiaopeng Tian, Chunhong Zhao, Jinbo Guo, Shurui Xie, Fengrong Yin, Xiaoxia Huo, Xiaolan Zhang

Journal: Biomed Res Int. 2017 ;2017():4612769.

 

Background. The sympathetic nervous system (SNS) is responsible for hepatic stellate cells (HSCs) activation and the accumulation of collagen that occurs in hepatic fibrogenesis. Carvedilol has been widely used for the complication of hepatic cirrhosis in the clinic. Furthermore, ...

Last Updated: 11 Apr 2017

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Platelet-derived growth factor A mRNA in platelets is associated with the degree of hepatic fibrosis in chronic hepatitis C.
 

Author(s): Aline Aki Tanikawa, Rejane Maria Tommasini Grotto, Giovanni Faria Silva, Adriana Camargo Ferrasi, Valéria Cristina Rodrigues Sarnighausen, Maria Inês de Moura Campos Pardini

Journal: Rev. Soc. Bras. Med. Trop.. ;50(1):113-116.

 

Transforming growth factor beta 1 (TGFB1) and platelet-derived growth factor (PDGF) are the main cytokines related to hepatic fibrogenesis.

Last Updated: 22 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatic fibrosis" returned 57 free, full-text review articles on human participants. First 3 results:

Evidence for a "Pathogenic Triumvirate" in Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease.
 

Author(s): Lu Jiang, Pingping Fang, James L Weemhoff, Udayan Apte, Michele T Pritchard

Journal: Biomed Res Int. 2016 ;2016():4918798.

 

Autosomal recessive polycystic kidney disease (ARPKD) is a severe monogenic disorder that occurs due to mutations in the PKHD1 gene. Congenital hepatic fibrosis (CHF) associated with ARPKD is characterized by the presence of hepatic cysts derived from dilated bile ducts and a robust, ...

Last Updated: 28 Nov 2016

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TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis.
 

Author(s): Fengyun Xu, Changwei Liu, Dandan Zhou, Lei Zhang

Journal: J. Histochem. Cytochem.. 2016 Mar;64(3):157-67.

 

Transforming growth factor-beta1 (TGF-β1), a key member in the TGF-β superfamily, plays a critical role in the development of hepatic fibrosis. Its expression is consistently elevated in affected organs, which correlates with increased extracellular matrix deposition. SMAD proteins ...

Last Updated: 25 Feb 2016

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[Inflammation and Hepatic Fibrosis, Then Hepatocellular Carcinoma].
 

Author(s): Oh Sang Kwon, Seong Han Choi, Ju Hyun Kim

Journal: Korean J Gastroenterol. 2015 Dec;66(6):320-4.

 

Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and cirrhosis develops in patients with chronic liver inflammation. Therefore, ...

Last Updated: 22 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

S-Shearwave Elastography for Assessment of Hepatic Fibrosis
 

Status: Not yet recruiting

Condition Summary: Liver Fibroses

 

Last Updated: 8 Feb 2017

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Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLD
 

Status: Recruiting

Condition Summary: Chronic Hepatitis B; Hepatic Fibrosis; Fatty Liver

 

Last Updated: 13 Oct 2016

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Optimized Treatment and Regression of HBV-induced Liver Fibrosis
 

Status: Recruiting

Condition Summary: Liver Fibrosis

 

Last Updated: 12 Jan 2016

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