Hemolytic uremic syndrome

Common Name(s)

Hemolytic uremic syndrome

Hemolytic uremic syndrome (HUS) is a complex disorder that may affect children after different infections, particularly bacterial infections that cause bloody diarrhea. HUS causes damage to the blood cells and the kidneys, which are organs in the abdomen responsible for filtering blood and creating urine. Symptoms of HUS commonly include bloody diarrhea, vomiting, pale skin tone, extreme tiredness, fever, blood in the urine, decreased urination, swelling, and confusion. A physician can diagnose HUS using blood, urine, and other lab tests. HUS usually requires treatment in the hospital to manage symptoms and prevent further organ damage.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemolytic uremic syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemolytic uremic syndrome" returned 358 free, full-text research articles on human participants. First 3 results:

Hemolytic uremic syndrome outbreak in Turkey in 2011.
 

Author(s): Zelal Ekinci, Cengiz Candan, Harika Alpay, Nur Canpolat, Sare Gülfem Akyüz, Zübeyde Gündüz, Ismail Dursun, Kenan Bek, Hasan Dursun, Emel Işıyel, Faruk Öktem, Yılmaz Tabel, İpek Akil, Ali Delibaş, Kaan Gülleroğlu, Nurver Akıncı, Nida Dinçel, Ozan Özkaya, Oğuz Söylemezoğlu

Journal: Turk. J. Pediatr.. ;55(3):246-52.

 

The aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS ...

Last Updated: 12 Nov 2013

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Eculizumab in atypical hemolytic-uremic syndrome.
 

Author(s): Christophe M Legendre, Christoph Licht, Chantal Loirat

Journal: N. Engl. J. Med.. 2013 Oct;369(14):1379-80.

 

Last Updated: 3 Oct 2013

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Determination of enterohemorrhagic Escherichia coli serotype O165:HNM infection in a hemolytic uremic syndrome patient with adenovirus seroype 41.
 

Author(s): Takayuki Konno, Jun Yatsuyanagi, Shiho Takahashi, Yuko Kumagai, Eriko Wada, Machiko Chiba, Shioko Saito

Journal: Jpn. J. Infect. Dis.. 2013 ;66(5):394-7.

 

A 4-year-old girl who was positive for adenovirus according to a rapid immunochromatographic test conducted at a hospital, progressed to hemorrhagic diarrhea and hemolytic uremic syndrome (HUS). The presence of adenovirus serotype 41 (AdV-41) was confirmed by TaqMan real-time PCR ...

Last Updated: 19 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemolytic uremic syndrome" returned 44 free, full-text review articles on human participants. First 3 results:

Atypical hemolytic uremic syndrome.
 

Author(s): David Kavanagh, Tim H Goodship, Anna Richards

Journal: Semin. Nephrol.. 2013 Nov;33(6):508-30.

 

Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease characterized by complement overactivation. Inherited defects in complement genes and acquired autoantibodies against complement ...

Last Updated: 28 Oct 2013

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Atypical hemolytic-uremic syndrome: the interplay between complements and the coagulation system.
 

Author(s): Ali Nayer, Arif Asif

Journal: Iran J Kidney Dis. 2013 Sep;7(5):340-5.

 

Hemolytic-uremic syndrome (HUS) is a rare life-threatening disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and impaired renal function. A thrombotic microangiopathy underlies the clinical features of HUS. In the majority of cases, HUS follows an infection ...

Last Updated: 27 Sep 2013

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New insights into Shiga toxin-mediated endothelial dysfunction in hemolytic uremic syndrome.
 

Author(s): Tania N Petruzziello-Pellegrini, Mozhgan Moslemi-Naeini, Philip A Marsden

Journal: Virulence. 2013 Aug;4(6):556-63.

 

Shiga toxin-producing E. coli represents a significant global health concern, especially as hypervirulent pathogens surface amidst outbreaks of hemolytic uremic syndrome (HUS). Shiga toxin (Stx) is key in the microangiopathic events underlying the disease and its central role is underscored ...

Last Updated: 27 Aug 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Atypcial Hemolytic-Uremic Syndrome (aHUS) Registry
 

Status: Recruiting

Condition Summary: Atypical Hemolytic-Uremic Syndrome

 

Last Updated: 16 Jan 2014

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Rituximab in Patients With Relapsed or Refractory TTP-HUS
 

Status: Recruiting

Condition Summary: Thrombotic Thrombocytopenic Purpura; Hemolytic Uremic Syndrome

 

Last Updated: 18 May 2010

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Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidney Disease
 

Status: Recruiting

Condition Summary: Atypical Hemolytic Uraemic Syndrome.

 

Last Updated: 1 Feb 2013

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