Hemoglobin E disease

Common Name(s)

Hemoglobin E disease

Hemoglobin E (HbE) disease is an inherited blood disorder characterized by an abnormal form of hemoglobin, called hemoglobin E. People with this condition have red blood cells that are smaller than normal and have an irregular shape. HbE disease is thought to be a benign condition. It is inherited in an autosomal recessive pattern and is caused by a particular mutation in the HBB gene. The mutation that causes hemoglobin E disease has the highest frequency among people of Southeast Asian heritage (Cambodian, Laotian, Vietnamese and Thai). However, it is also found in people of Chinese, Filipino, Asiatic Indian, and Turkish descent.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemoglobin E disease" for support, advocacy or research.

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American Sickle Cell Anemia Association

ASCAA is an organization that provides quality and comprehensive services through diagnostic testing, evaluation, couseling, and supportive services to individuals and families at-risk for sickle cell disease.

Last Updated: 11 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemoglobin E disease" for support, advocacy or research.

Logo
American Sickle Cell Anemia Association

ASCAA is an organization that provides quality and comprehensive services through diagnostic testing, evaluation, couseling, and supportive services to individuals and families at-risk for sickle cell disease.

http://www.ascaa.org

Last Updated: 11 Feb 2013

View Details

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemoglobin E disease" returned 6 free, full-text research articles on human participants. First 3 results:

Hemoglobin E disease with concomitant tuberculosis.
 

Author(s): Deepali Jain, Sanjeev Kumar Gupta, Tejinder Singh

Journal: Indian J Pathol Microbiol. ;51(4):570.

 

Last Updated: 14 Nov 2008

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Once-monthly subcutaneous C.E.R.A. maintains stable hemoglobin control in patients with chronic kidney disease on dialysis and converted directly from epoetin one to three times weekly.
 

Author(s): Wladyslaw Sulowicz, Francesco Locatelli, Jean-Philippe Ryckelynck, Jozsef Balla, Botond Csiky, Kevin Harris, Patricia Ehrhard, Ulrich Beyer,

Journal: Clin J Am Soc Nephrol. 2007 Jul;2(4):637-46.

 

C.E.R.A., a continuous erythropoietin receptor activator, is in development to provide anemia correction and stable maintenance of hemoglobin (Hb) levels at extended administration intervals in patients with chronic kidney disease (CKD). This study examined its efficacy and safety ...

Last Updated: 16 Aug 2007

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Sickle cell-hemoglobin E disease in an Indian family.
 

Author(s): S Mukhopadhyay, N Kumar, R Saxena

Journal: Indian J Pathol Microbiol. 2001 Oct;44(4):465-6.

 

Last Updated: 30 May 2002

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemoglobin E disease" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov