Alpha Thalassemia Trait

Common Name(s)

Alpha Thalassemia Trait

Alpha thalassemia trait is a type of hemoglobinopathy, or hemoglobin disorder. Hemoglobin is a chemical found in the blood and its function is to carry oxygen from the lungs to the rest of the body. Hemoglobinopathies occur when there is a problem with this chemical and it is not able to function correctly. Alpha thalessemia trait is a more mild form of alpha thaessemia, and does not lead to the more severe forms called hemoglobin H disease and hydrops fetalis. Symptoms include pale skin, weakness, and fatigue. It may also result in temporary yellowing of the skin (jaundice) or anemia. This is a genetic disorder, meaning that it may be transferred from parents to their children. This condition often requires lifelong management, including frequent check-ups, different vitamins, such as folic acid, and potentially blood transfusions. Treatment mainly depends on age, medical history, severity of the disease.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alpha Thalassemia Trait" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alpha Thalassemia Trait" returned 11 free, full-text research articles on human participants. First 3 results:

Skeletal muscle structural and energetic characteristics in subjects with sickle cell trait, alpha-thalassemia, or dual hemoglobinopathy.
 

Author(s): Lucile Vincent, Léonard Féasson, Samuel Oyono-Enguéllé, Viviane Banimbek, Géraldine Monchanin, Macias Dohbobga, Dieudonné Wouassi, Cyril Martin, David Gozal, André Geyssant, Patrice Thiriet, Christian Denis, Laurent Messonnier

Journal: J. Appl. Physiol.. 2010 Sep;109(3):728-34.

 

Previous studies have shown that subjects with sickle cell trait (SCT), alpha-thalassemia (alpha-t), and the dual hemoglobinopathy (SCT/alpha-t) manifest subtle, albeit significant, differences during exercise. To better understand such differences, we assessed skeletal muscle histomorphological ...

Last Updated: 10 Sep 2010

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Remodeling of skeletal muscle microvasculature in sickle cell trait and alpha-thalassemia.
 

Author(s): Lucile Vincent, Léonard Féasson, Samuel Oyono-Enguéllé, Viviane Banimbek, Christian Denis, Catherine Guarneri, Emeline Aufradet, Géraldine Monchanin, Cyril Martin, David Gozal, Macias Dohbobga, Dieudonné Wouassi, Martin Garet, Patrice Thiriet, Laurent Messonnier

Journal: Am. J. Physiol. Heart Circ. Physiol.. 2010 Feb;298(2):H375-84.

 

The influence of sickle cell trait and/or alpha-thalassemia on skeletal muscle microvascular network characteristics was assessed and compared with control subjects [hemoglobin (Hb) AA] in 30 Cameroonian residents [10 HbAA, 5 HbAA alpha-thalassemia (alpha-t), 6 HbAS, and 9 HbASalpha-t] ...

Last Updated: 21 Jan 2010

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Effects of progressive and maximal exercise on plasma levels of adhesion molecules in athletes with sickle cell trait with or without alpha-thalassemia.
 

Author(s): Geraldine Monchanin, Laura D Serpero, Philippe Connes, Julien Tripette, Dieudonné Wouassi, Laurent Bezin, Alain Francina, Jeanne Ngongang, Monica de la Peña, Raphael Massarelli, David Gozal, Patrice Thiriet, Cyril Martin

Journal: J. Appl. Physiol.. 2007 Jan;102(1):169-73.

 

The aim of the study was to examine the effects of exercise on soluble vascular cell adhesion molecule-1 (sVCAM-1) and intercellular adhesion molecule-1 (sICAM-1) in sickle cell trait (SCT) athletes with or without alpha-thalassemia. Six athletes with SCT, seven athletes with both ...

Last Updated: 8 Jan 2007

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alpha Thalassemia Trait" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.