Hemangioma

Common Name(s)

Hemangioma

A hemangioma is a noncancerous clumping of blood vessels found on the skin or internal organs, most commonly the liver. Hemangiomas are often present at birth or develop in the first few months of life. Skin hemangiomas are quite common, mostly found on the face and neck. Liver hemangiomas rarely cause symptoms. Cavernous hemangiomas most commonly form on the brain or spinal cord and have a different outcome than the other types of hemangiomas. The cause of the clumping of the blood vessels is not well understood.

Skin hemangiomas form on the surface of the skin or in the fatty layer just underneath. It may at first appear as a flat birth mark, but will become a raised red rubbery or spongy lump over the first year. Most will stop growing at this point and after some time will begin to go away. Most skin hemangiomas disappear by age 10, though a faint discoloration may remain. Hemangiomas may affect the vision if they are on the eyelid.

Liver hemangiomas can form within the organ or on its surface. Liver hemangiomas may be estrogen sensitive, meaning they may grow if a woman is given estrogen supplements during menopause. Hemangiomas may also form on the kidneys, colon, and lungs. A hemangioma on any of these organs rarely causes problems unless it grows too large or multiple hemangiomas form. Symptoms may then include nausea, vomiting, abdominal pain, and loss of appetite. Occasionally they interfere with breathing. However, they usually go unnoticed unless picked up by an imaging study (MRI) being done for another reason.

Diagnosis is made by physical exam and imaging studies. Many hemangiomas will go away without treatment. If causing problems, treatment may include laser procedures, steroid injections, medication or surgical removal. If you or your child has been diagnosed with hemangioma, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioma" returned 736 free, full-text research articles on human participants. First 3 results:

[Changes in ambulatory electrocardiographic findings after oral administration of low-dose propranolol in infants with hemangioma].
 

Author(s): Lan-Fen Yi, Hong-Xia Wen, Sui Huang, Mei Qiu, Jing-Yang Zhang, Xiao-Xiao Cao

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2016 Apr;18(4):345-9.

 

To investigate the effects of oral administration of low-dose propranolol on heart rate variability (HRV), acceleration capacity (AC), deceleration capacity (DC), and cardiac conduction in the treatment of infantile hemangioma.

Last Updated: 21 Apr 2016

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Intracranial capillary hemangioma misdiagnosed as a meningioma.
 

Author(s): Carlos B Dabdoub, Mario Chavez, Jose Luis Ferrufino, Edith Claros, Elisabeth do Nascimento Silveira, Carlos F Dabdoub

Journal: Arq Neuropsiquiatr. 2016 Apr;74(4):356-7.

 

Last Updated: 21 Apr 2016

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Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma.
 

Author(s): Ugur M Ayturk, Javier A Couto, Steven Hann, John B Mulliken, Kaitlin L Williams, August Yue Huang, Steven J Fishman, Theonia K Boyd, Harry P W Kozakewich, Joyce Bischoff, Arin K Greene, Matthew L Warman

Journal: Am. J. Hum. Genet.. 2016 Apr;98(4):789-95.

 

Congenital hemangioma is a rare vascular tumor that forms in utero. Postnatally, the tumor either involutes quickly (i.e., rapidly involuting congenital hemangioma [RICH]) or partially regresses and stabilizes (i.e., non-involuting congenital hemangioma [NICH]). We hypothesized that ...

Last Updated: 9 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioma" returned 73 free, full-text review articles on human participants. First 3 results:

Hepatocellular carcinoma in nonalcoholic fatty liver disease mimicking benign hemangioma: two case reports and literature review.
 

Author(s): Haidong Tan, Li Xu, Xiaolei Liu, Shuang Si, Yongliang Sun, Liguo Liu, Wenying Zhou, Zhiying Yang

Journal:

 

To study the clinical features of nonalcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC).

Last Updated: 29 Jan 2016

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Spontaneous rupture of hepatic hemangioma: a case report and literature review.
 

Author(s): Wei Zhao, Xiao Guo, Jiahong Dong

Journal:

 

Hepatic hemangioma, a common benign tumor of the liver, has caused great threats to the public health. Most patients have an excellent prognosis because of the benign nature of hemangioma. On some occasions, spontaneous rupture of hepatic hemangioma is rarely observed in patients. ...

Last Updated: 1 Jan 2016

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Renal cavernous hemangioma: robot-assisted partial nephrectomy with selective warm ischemia. Case report and review of the literature.
 

Author(s): G Ceccarelli, M Codacci Pisanelli, A Patriti, A Biancafarina

Journal: G Chir. ;36(5):197-200.

 

Renal hemangioma is a relatively rare benign tumor with a wide range of clinical and radiological presentation, not easy to differentiate preoperatively from a renal cancer. Due to its benign nature complete surgical resection is the recommended therapy and is considered curative. ...

Last Updated: 29 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nadolol Versus Propranolol in Children With Infantile Hemangiomas
 

Status: Recruiting

Condition Summary: Infantile Hemangioma

 

Last Updated: 4 Jan 2016

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Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH)
 

Status: Not yet recruiting

Condition Summary: Infantile Hemangioma

 

Last Updated: 21 Sep 2016

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