Hemangioma

Common Name(s)

Hemangioma

A hemangioma is a noncancerous clumping of blood vessels found on the skin or internal organs, most commonly the liver. Hemangiomas are often present at birth or develop in the first few months of life. Skin hemangiomas are quite common, mostly found on the face and neck. Liver hemangiomas rarely cause symptoms. Cavernous hemangiomas most commonly form on the brain or spinal cord and have a different outcome than the other types of hemangiomas. The cause of the clumping of the blood vessels is not well understood.

Skin hemangiomas form on the surface of the skin or in the fatty layer just underneath. It may at first appear as a flat birth mark, but will become a raised red rubbery or spongy lump over the first year. Most will stop growing at this point and after some time will begin to go away. Most skin hemangiomas disappear by age 10, though a faint discoloration may remain. Hemangiomas may affect the vision if they are on the eyelid.

Liver hemangiomas can form within the organ or on its surface. Liver hemangiomas may be estrogen sensitive, meaning they may grow if a woman is given estrogen supplements during menopause. Hemangiomas may also form on the kidneys, colon, and lungs. A hemangioma on any of these organs rarely causes problems unless it grows too large or multiple hemangiomas form. Symptoms may then include nausea, vomiting, abdominal pain, and loss of appetite. Occasionally they interfere with breathing. However, they usually go unnoticed unless picked up by an imaging study (MRI) being done for another reason.

Diagnosis is made by physical exam and imaging studies. Many hemangiomas will go away without treatment. If causing problems, treatment may include laser procedures, steroid injections, medication or surgical removal. If you or your child has been diagnosed with hemangioma, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioma" returned 701 free, full-text research articles on human participants. First 3 results:

Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma.
 

Author(s): Natália Bertoni, Lied M S Pereira, Fábio E Severino, Regina Moura, Winston B Yoshida, Patricia P Reis

Journal:

 

Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited. Currently, microRNAs (miRNAs) have been shown as gene expression regulators with an important role in disease pathogenesis. ...

Last Updated: 16 Jan 2016

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Early Surgical Management of Large Scalp Infantile Hemangioma Using the TopClosure® Tension-Relief System.
 

Author(s): Zhanyong Zhu, Xilin Yang, Yueqiang Zhao, Huajun Fan, Mosheng Yu, Moris Topaz

Journal: Medicine (Baltimore). 2015 Nov;94(47):e2128.

 

Infantile hemangiomas (IHs) are the most common benign vascular neoplasms of infancy and childhood. The majority do not need medical intervention. However, large ulcerated scalp IHs may lead to fatal bleeding as well as severe cosmetic disfigurement that indicate early surgical excision, ...

Last Updated: 4 Dec 2015

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Last Updated: 28 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioma" returned 61 free, full-text review articles on human participants. First 3 results:

Renal cavernous hemangioma: robot-assisted partial nephrectomy with selective warm ischemia. Case report and review of the literature.
 

Author(s): G Ceccarelli, M Codacci Pisanelli, A Patriti, A Biancafarina

Journal: G Chir. ;36(5):197-200.

 

Renal hemangioma is a relatively rare benign tumor with a wide range of clinical and radiological presentation, not easy to differentiate preoperatively from a renal cancer. Due to its benign nature complete surgical resection is the recommended therapy and is considered curative. ...

Last Updated: 29 Dec 2015

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Hepatic hemangioma -review-.
 

Author(s): N Bajenaru, V Balaban, F Săvulescu, I Campeanu, T Patrascu

Journal: J Med Life. 2015 ;8 Spec Issue():4-11.

 

Hepatic hemangiomas are benign tumors of the liver consisting of clusters of blood-filled cavities, lined by endothelial cells, fed by the hepatic artery. The vast majority of HH are asymptomatic, most often being discovered incidentally during imaging investigations for various unrelated ...

Last Updated: 12 Sep 2015

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A giant cord hemangioma with extramedullary hematopoiesis and elevated maternal serum human chorionic gonadotropin: a case report and review of the literature.
 

Author(s): Kieko Hara, Yuki Fukumura, Tsuyoshi Saito, Atsushi Arakawa, Hitomi Okabe, Satoru Takeda, Takashi Yao

Journal:

 

A case of prenatally diagnosed, giant cord hemangioma is reported, which was accompanied by the elevation of maternal serum alpha-fetoprotein (MS-AFP) and human chorionic gonadotropin (MS-hCG) levels. A 30-year-old woman without a previous history of gravida or para, presented with ...

Last Updated: 4 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Topical Timolol Gel for the Treatment of Infantile Hemangiomas
 

Status: Not yet recruiting

Condition Summary: Hemangioma

 

Last Updated: 22 May 2014

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Topical Timolol 0.5% Solution for Proliferating Infantile Hemangiomas
 

Status: Recruiting

Condition Summary: Hemangioma; Infant

 

Last Updated: 18 Jun 2010

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Last Updated: 25 Feb 2016

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