Hemangioendothelioma

Common Name(s)

Hemangioendothelioma

The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. The term has also been applied to those that show "borderline" behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas. Hemangioendotheliomas are caused by abnormal growth of blood vessel cells, although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ, such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize). Examples of types of hemangioendotheliomas include spindle cell hemangioma; papillary intralymphatic (Dabska tumor); retiform; kaposiform; epithelioid; pseudomyogenic (epithelioid sarcoma-like hemangioendothelioma); and composite. Treatment depends on the type of hemangioendothelioma present but typically includes surgical excision (removal).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioendothelioma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioendothelioma" returned 103 free, full-text research articles on human participants. First 3 results:

[Radical removal of a malignant mediastinum hemangioendothelioma with restoration of the main blood supply to the brain].
 

Author(s): M I Davydov, D Iu Usachev, B E Polotskiĭ, V A Sobolevskiĭ, K K Laktionov, L A Nikulichev, S S Gerasimov, V A Lukshin, E S Gorobets, V E Gruzdev, A V Shmigel'skiĭ, A Iu Beliaev, I E Volodina

Journal: Zh Vopr Neirokhir Im N N Burdenko. 2013 ;77(4):61-8; discussion 68.

 

46 year old man appealed to the Cancer Research Center of RAMS in October 2012 with unverified anterior superior mediastinal tumor, which was diagnosed in 2010. Progressive compartment syndrome of the superior vena cava was observed. On examination: CT, MRI, angiography, histological ...

Last Updated: 24 Dec 2013

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Epithelioid hemangioendothelioma of the liver.
 

Author(s): Keum Ha Choi, Woo Sung Moon

Journal: Clin Mol Hepatol. 2013 Sep;19(3):315-9.

 

Last Updated: 17 Oct 2013

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[Successful treatment with prednisone in a critical ill newborn with symptomatic multifocal infantile hepatic hemangioendothelioma].
 

Author(s): Miurkis Endis Miranda, Ramón Villamil Martínez, Pastor Alexander Thomas Olivares, Juan Jose Trujillo Gálvez

Journal: Arch Argent Pediatr. 2013 Oct;111(5):e129-e132.

 

Infantile hepatic hemangioendothelioma is the most common vascular tumor of the liver in infancy. The diagnosis can be enunciated without histological defnition, if the clinical, analytical and images fndings are very suggestive; particularly in children less than six months old, ...

Last Updated: 4 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioendothelioma" returned 10 free, full-text review articles on human participants. First 3 results:

Composite hemangioendothelioma arising from the kidney: case report with review of the literature.
 

Author(s): Jin Zhang, Bo Wu, Gui-Qian Zhou, Ru-Song Zhang, Xue Wei, Bo Yu, Zhen-Feng Lu, Heng-Hui Ma, Qun-Li Shi, Xiao-Jun Zhou

Journal:

 

Reported herein is a medical curiosities vascular tumor primary arising from the kidney and exhibiting unique histopathological features. A 32-year-old woman underwent a total nephrectomy of right kidney because of a mass localized in the inferior pole. Distinct from other vascular ...

Last Updated: 16 Sep 2013

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Malignant epithelioid hemangioendothelioma progressing after chemotherapy and Interferon treatment: a case presentation and a brief review of the literature.
 

Author(s): Lutfiye Demir, Alper Can, Rukiye Oztop, Ahmet Dirican, Vedat Bayoglu, Murat Akyol, Yuksel Kucukzeybek, Cigdem Erten, Isil Somali, Mustafa Oktay Tarhan

Journal: J Cancer Res Ther. ;9(1):125-7.

 

Epithelioid hemangioendothelioma is a rare, low-grade malignant vascular tumour. It is frequently seen in the liver, but can occur in the lungs, bones, and other soft tissues. Although survival time might be reasonable in cases that can undergo liver transplantation, there is no consensus ...

Last Updated: 11 Apr 2013

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Multicentric epithelioid hemangioendothelioma involving the same lower extremity: a case report and review of literature.
 

Author(s): Qingjun Liu, Jianyun Miao, Kejian Lian, Lianshui Huang, Zhenqi Ding

Journal: Int J Med Sci. 2011 ;8(7):558-63.

 

Epithelioid hemangioendothelioma (EH) is an uncommon low-grade malignant soft-tissue tumor; no case has been previously reported where multicentric epithelioid hemangioendothelioma occurred in the same lower extremity at different sites. We report a case involving the common peroneal ...

Last Updated: 30 Sep 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Alveolar Soft-part Sarcoma; Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Fibrous Histiocytoma; Adult Malignant Hemangiopericytoma; Adult Malignant Mesenchymoma; Adult Neurofibrosarcoma; Adult Rhabdomyosarcoma; Adult Synovial Sarcoma; Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Hemangioendothelioma; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Hemangiopericytoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Dermatofibrosarcoma Protuberans; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 26 Jul 2014

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A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors
 

Status: Not yet recruiting

Condition Summary: Kaposiform Hemangioendothelioma (KHE); Kasabach-Merritt Syndrome; Tufted Angioma

 

Last Updated: 8 Apr 2014

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Pazopanib Hydrochloride Followed By Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Chondrosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Fibrous Histiocytoma; Adult Malignant Hemangiopericytoma; Adult Malignant Mesenchymoma; Adult Neurofibrosarcoma; Adult Synovial Sarcoma; Dermatofibrosarcoma Protuberans; Stage IIA Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 16 Jun 2014

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