Hemangioendothelioma

Common Name(s)

Hemangioendothelioma

The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. The term has also been applied to those that show "borderline" behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas. Hemangioendotheliomas are caused by abnormal growth of blood vessel cells, although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ, such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize). Examples of types of hemangioendotheliomas include spindle cell hemangioma; papillary intralymphatic (Dabska tumor); retiform; kaposiform; epithelioid; pseudomyogenic (epithelioid sarcoma-like hemangioendothelioma); and composite. Treatment depends on the type of hemangioendothelioma present but typically includes surgical excision (removal).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioendothelioma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioendothelioma" returned 172 free, full-text research articles on human participants. First 3 results:

Diagnostic utility of FOSB immunohistochemistry in pseudomyogenic hemangioendothelioma and its histological mimics.
 

Author(s): Shintaro Sugita, Hiroshi Hirano, Noriaki Kikuchi, Terufumi Kubo, Hiroko Asanuma, Tomoyuki Aoyama, Makoto Emori, Tadashi Hasegawa

Journal:

 

Pseudomyogenic hemangioendothelioma (PHE) is an unusual vascular tumor of intermediate malignancy that rarely metastasizes and tends to arise in the lower limbs of young adults and children. Histologically, PHE shows fascicular proliferation of eosinophilic spindle cells and/or epithelioid ...

Last Updated: 12 Aug 2016

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Epithelioid hemangioendothelioma in the thorax: Clinicopathologic, CT, PET, and prognostic features.
 

Author(s): Jung Han Woo, Tae Jung Kim, Kyung Soo Lee, Tae Sung Kim, Byung-Tae Kim

Journal: Medicine (Baltimore). 2016 Jul;95(30):e4348.

 

Little is known about prognostic factors in epithelioid hemangioendothelioma (EHE). We aimed to identify prognostic factors among various clinicopathologic and imaging features of thoracic EHEs.Forty-two patients (male:female = 20:22; median age, 49 years) of EHEs with (n = 19) ...

Last Updated: 30 Jul 2016

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Infantile rhabdoid tumor mimicking hepatic hemangioendothelioma.
 

Author(s): Serhan Kupeli, Ahmet Yöntem, Nejat Narli, Figen Doran, Süreyya Soyupak

Journal: J Cancer Res Ther. ;12(1):430-1.

 

Last Updated: 13 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioendothelioma" returned 23 free, full-text review articles on human participants. First 3 results:

A case report of retiform hemangioendothelioma as pleural nodules with literature review.
 

Author(s): Qingqing Liu, Ruoyun Ouyang, Ping Chen, Rui Zhou

Journal:

 

Retiform hemangioendothelioma (RH) is a rare low-grade variant of angiosarcoma mostly reported on dermis or subcutaneously. A 30-year-old woman suffering from dry cough, dyspnea and pleural effusion has been described. Distinctive symptoms and lesions on high resolution computed tomography ...

Last Updated: 27 Oct 2015

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Retiform hemangioendothelioma over forehead: A rare tumor treated with chemoradiation and a review of literature.
 

Author(s): Anup Sunil Tamhankar, Abhishek Vaidya, Prathamesh Pai

Journal: J Cancer Res Ther. ;11(3):657.

 

Retiform hemangioendothelioma (RH) is low grade tumor of skin and subcutaneous tissue. It needs to be differentiated from angiosarcoma as RH has excellent prognosis. It is usually seen in young adults on extremities. Sometimes it may mimic benign conditions and can delay treatment. ...

Last Updated: 13 Oct 2015

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Hepatic epithelioid hemangioendothelioma metastasized to the peritoneum, omentum and mesentery: a case report.
 

Author(s): Sanita Gurung, Hua Fu, Wei Wen Zhang, Yong Hong Gu

Journal:

 

Epithelioid hemangioendothelioma (EHAE) is a malignant vascular tumor derived from endothelial cell often misdiagnosed as Hepatic carcinoma on the basis of radiological features. Till now etiology of this rare curiosity is unknown but it is related with use of oral contraceptives ...

Last Updated: 20 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors
 

Status: Recruiting

Condition Summary: Kaposiform Hemangioendothelioma (KHE); Kasabach-Merritt Syndrome; Tufted Angioma

 

Last Updated: 13 Oct 2016

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Safety and Efficacy of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular Embolization. A Phase IV Study.
 

Status: Not yet recruiting

Condition Summary: Congenital Hemangioma; Hemangioendothelioma; Angiosarcoma; Arteriovenous Malformation

 

Last Updated: 10 Feb 2017

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Identification of Biomarkers for Patients With Vascular Anomalies
 

Status: Recruiting

Condition Summary: Vascular Anomaly; Generalized Lymphatic Anomaly; Kaposiform Hemangioendothelioma; Kaposiform Lymphangiomatosis; Gorham-Stout Disease

 

Last Updated: 20 Dec 2016

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