Hemangioblastoma

Common Name(s)

Hemangioblastoma

A hemangioblastoma is a benign, highly vascular tumor that can occur in the brain, spinal cord, and retina (the light-sensitive tissue that lines the back of the eye). This tumor accounts for about 2% of brain tumors. As it enlarges, it presses on the brain and can cause neurological symptoms, such as headaches, weakness, sensory loss, balance and coordination problems, and/or hydrocephalus (a buildup of spinal fluid in the brain). Most hemangioblastomas occur sporadically. However, some people develop hemangioblastomas as part of a genetic syndrome called von Hippel-Lindau syndrome. These people usually develop multiple tumors within the brain and spinal cord over their lifetime.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioblastoma" returned 66 free, full-text research articles on human participants. First 3 results:

Giant solid hemangioblastoma of the cerebellopontine angle: a technically challenging case.
 

Author(s): Bijesh Ravindran Nair, Vivek Joseph, Geeta Chacko, Shyamkumar Nidugala Keshava

Journal: Neurol India. ;62(2):228-9.

 

Last Updated: 14 May 2014

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Clinical effectiveness of preoperative embolization for cerebellar hemangioblastoma.
 

Author(s): Ai-Hua Liu, Tang-Ming Peng, Zhen Wu, Xin-Ru Xiao, Chu-Han Jiang, Zhong-Xue Wu, You-Xiang Li

Journal: Asian Pac. J. Cancer Prev.. 2013 ;14(9):5179-83.

 

The cerebellar hemangioblastoma (CHB) has an abundant blood supply and deep anatomical location. Complete surgical resection is generally very difficult. This study investigated the safety and effectiveness of preoperative embolization followed by surgical resection of CHB in a large ...

Last Updated: 1 Nov 2013

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Sporadic hemangioblastoma of the kidney with PAX2 and focal CD10 expression: report of a case.
 

Author(s): Jin-Gui Jiang, Qiu Rao, Qiu-Yuan Xia, Pin Tu, Zhen-Feng Lu, Qin Shen, Ru-Song Zhang, Bo Yu, Xiao-Jun Zhou, Shan-Shan Shi, Qun-Li Shi

Journal:

 

In this study, we presented an additional case of renal hemangioblastoma, which demonstrates PAX2 and focal CD10 expression. Histologically, the tumor consisted of sheets of oval or polygonal cells and a prominent vascular network. The tumor cells varied in size, and possessed pale ...

Last Updated: 16 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioblastoma" returned 10 free, full-text review articles on human participants. First 3 results:

Sporadic hemangioblastoma of the retroperitoneum.
 

Author(s): Yong Huang, Xiang-Chun Han, Guo-Shi Lv

Journal:

 

Hemangioblastoma is a rare neoplasm occurred in soft tissue. Herein, we present an intriguing case of sporadic hemangioblastoma in the retroperitoneum occurring in a 59-year-old male. The tumor was characterized by an alternation of cellular and paucicellular areas surrounded by a ...

Last Updated: 12 May 2014

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Brachyury: a diagnostic marker for the differential diagnosis of chordoma and hemangioblastoma versus neoplastic histological mimickers.
 

Author(s): Valeria Barresi, Antonio Ieni, Giovanni Branca, Giovanni Tuccari

Journal: Dis. Markers. 2014 ;2014():514753.

 

Brachyury is a transcription factor which is required for posterior mesoderm formation and differentiation as well as for notochord development during embryogenesis. Due to its expression in the neoplastic cells of chordoma, a malignant tumour deriving from notochordal remnants, but ...

Last Updated: 4 Mar 2014

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Hemangioblastoma of the filum terminale associated with von Hippel-Lindau disease: a case report.
 

Author(s): Bulent Tucer, Mehmet Ali Ekici, Burak Kazanci, Bulent Guclu

Journal: Turk Neurosurg. 2013 ;23(5):672-5.

 

We report a 41-year-old man who presented with low back pain, lower extremity paresthesia, urinary retention and constipation. Magnetic resonance imaging showed a vascular intradural-extramedullary lesion at the second lumbar vertebral level. His medical history revealed that he had ...

Last Updated: 8 Oct 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Psychosocial Consequences of the Screening of Von Hippel Lindau Diseases for Patients Operated for a hémangioblastoma of Nervous Centrasl System
 

Status: Recruiting

Condition Summary: Hemangioblastoma (HB) of the Central Nervous System (CNS)

 

Last Updated: 18 Apr 2014

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