Hemangioblastoma

Common Name(s)

Hemangioblastoma

A hemangioblastoma is a benign, highly vascular tumor that can occur in the brain, spinal cord, and retina (the light-sensitive tissue that lines the back of the eye). This tumor accounts for about 2% of brain tumors. As it enlarges, it presses on the brain and can cause neurological symptoms, such as headaches, weakness, sensory loss, balance and coordination problems, and/or hydrocephalus (a buildup of spinal fluid in the brain). Most hemangioblastomas occur sporadically. However, some people develop hemangioblastomas as part of a genetic syndrome called von Hippel-Lindau syndrome. These people usually develop multiple tumors within the brain and spinal cord over their lifetime.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioblastoma" returned 84 free, full-text research articles on human participants. First 3 results:

Biological and clinical impact of hemangioblastoma-associated peritumoral cysts in von Hippel-Lindau disease.
 

Author(s): Kristin Huntoon, Tianxia Wu, J Bradley Elder, John A Butman, Emily Y Chew, W Marston Linehan, Edward H Oldfield, Russell R Lonser

Journal: J. Neurosurg.. 2016 Apr;124(4):971-6.

 

Peritumoral cysts are frequently associated with CNS hemangioblastomas and often underlie neurological morbidity and mortality. To determine their natural history and clinical impact, the authors prospectively analyzed hemangioblastoma-associated peritumoral cysts in patients with ...

Last Updated: 1 Apr 2016

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Propranolol reduces viability and induces apoptosis in hemangioblastoma cells from von Hippel-Lindau patients.
 

Author(s): Virginia Albiñana, Karina Villar Gómez de Las Heras, Gemma Serrano-Heras, Tomás Segura, Ana Belén Perona-Moratalla, Mercedes Mota-Pérez, José María de Campos, Luisa María Botella

Journal:

 

Von Hippel-Lindau (VHL) disease is a rare oncological disease with an incidence of 1:36,000, and is characterized by the growth of different types of tumors: hemangioblastomas in the central nervous system (CNS) and retina, renal carcinoma, pheochromocytomas, pancreatic serous cystadenoma, ...

Last Updated: 23 Sep 2015

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Clear cell renal cell carcinoma with hemangioblastoma-like features: A recently described pattern with unusual immunohistochemical profile.
 

Author(s): Sankalp Sancheti, Santosh Menon, Satyadip Mukherjee, Indu Arun

Journal: Indian J Pathol Microbiol. ;58(3):354-5.

 

The diagnosis of clear cell renal cell carcinoma may sometimes pose challenges because of the presence of uncharacteristic morphology, varied immunophenotypic patterns and due to lack of molecular or genetic determinants. More often, the morphological variations can be easily overlooked ...

Last Updated: 15 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioblastoma" returned 18 free, full-text review articles on human participants. First 3 results:

Suprasellar hemangioblastoma without von Hippel-Lindau disease: a case report and literature review.
 

Author(s): Zhen Li, Tianda Feng, Hao Teng, Yi Hu, Yilong Yao, Yunhui Liu

Journal:

 

Suprasellar hemangioblastoma (HBL) without von Hippel-Lindau (VHL) disease is extremely rare. A 51-year-old woman presented with headache and progressively deteriorating bilateral visual disturbance for 4 months. Magnetic resonance imaging (MRI) revealed a 2.5-cm solid mass in the ...

Last Updated: 11 Aug 2015

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Extraneural hemangioblastoma of the kidney: the challenge for clinicopathological diagnosis.
 

Author(s): Yong Wu, Tao Wang, Pei-Pei Zhang, Xiaoqun Yang, Jian Wang, Chao-Fu Wang

Journal: J. Clin. Pathol.. 2015 Dec;68(12):1020-5.

 

Hemangioblastoma is a benign cerebellar tumour which may occur as a sporadic entity or in association with von Hippel-Lindau (VHL) disease in approximately 25% of cases. Renal hemangioblastoma (RH) is an extremely rare and newly recognised tumour. Here, we describe five cases of RH, ...

Last Updated: 25 Nov 2015

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Intratumoral hemorrhage in a patient with cerebellar hemangioblastoma: a case report and review.
 

Author(s): Zhen Wang, Jun Hu, Liang Xu, Jay Malaguit, Sheng Chen

Journal: Medicine (Baltimore). 2015 Jan;94(4):e497.

 

Spontaneous hemorrhage is rarely associated with hemangioblastomas. Intratumoral hemorrhage occurring in cerebellar hemangioblastomas is more rare. A 25-year-old man was admitted to our hospital with headache. We found a round cystic lesion with solid part in the right cerebellum. ...

Last Updated: 30 Jan 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.