Hemangioblastoma

Common Name(s)

Hemangioblastoma

A hemangioblastoma is a benign, highly vascular tumor that can occur in the brain, spinal cord, and retina (the light-sensitive tissue that lines the back of the eye). This tumor accounts for about 2% of brain tumors. As it enlarges, it presses on the brain and can cause neurological symptoms, such as headaches, weakness, sensory loss, balance and coordination problems, and/or hydrocephalus (a buildup of spinal fluid in the brain). Most hemangioblastomas occur sporadically. However, some people develop hemangioblastomas as part of a genetic syndrome called von Hippel-Lindau syndrome. These people usually develop multiple tumors within the brain and spinal cord over their lifetime.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioblastoma" returned 85 free, full-text research articles on human participants. First 3 results:

Genotype-phenotype analysis of von Hippel-Lindau syndrome in Korean families: HIF-α binding site missense mutations elevate age-specific risk for CNS hemangioblastoma.
 

Author(s): Jee-Soo Lee, Ji-Hyun Lee, Kyu Eun Lee, Jung Hee Kim, Joon Mo Hong, Eun Kyung Ra, Soo Hyun Seo, Seung Jun Lee, Man Jin Kim, Sung Sup Park, Moon-Woo Seong

Journal:

 

von Hippel-Lindau (VHL) disease is a rare hereditary tumor syndrome caused by VHL gene mutations that is characterized by heterogeneous phenotypes such as benign/malignant tumors of the central nervous system, retina, kidney, adrenal gland, and pancreas. The genotype-phenotype correlation ...

Last Updated: 31 Dec 1969

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[Cerebellar hemangioblastoma and thrombocytopenia: Report of one case].
 

Author(s): Santiago Patiño G

Journal: Rev Med Chil. 2016 Apr;144(4):521-5.

 

The association between vascular tumors and thrombocytopenia is rare. Kasabach-Merritt Syndrome is seen in childhood and is characterized by hemangiomas and thrombocytopenia. A 42 years-old man with a cerebellar hemangioblastoma and thrombocytopenia, admitted with a subarachnoid hemorrhage ...

Last Updated: 31 Dec 1969

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Hemangioblastoma located in the posterior incisural space mimicking a tentorial meningioma: a case report.
 

Author(s): Alejandra T Rabadán, Diego A Hernández, Leonardo Paz

Journal:

 

The most common type of vascularized tumor located in the posterior incisural space in older patients is the falcotentorial meningioma. Solid hemangioblastomas are rarely found in this particular area of the brain. To the best of our knowledge, the case of only one patient harboring ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioblastoma" returned 20 free, full-text review articles on human participants. First 3 results:

Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.
 

Author(s): Xiu-Peng Zhang, Yang Liu, Di Zhang, Qin Zheng, Chen Wang, Liang Wang, Qing-Chang Li, Xue-Shan Qiu, En-Hua Wang

Journal:

 

Imaging and histology of clear-cell ependymoma and cerebellum-based hemangioblastoma are similar; distinguishing between them is a diagnostic challenge.

Last Updated: 31 Dec 1969

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[Extradural spinal cord hemangioblastoma (a case report and literature review)].
 

Author(s): N A Konovalov, L V Shishkina, D S Asyutin, R A Onoprienko, V A Korolishin, B A Zakirov, M A Martynova, I U Cherkiev, A L Pogosyan, S Yu Timonin

Journal: Zh Vopr Neirokhir Im N N Burdenko. ;80(6):88-92.

 

Hemangioblastoma is a rare CNS vascular tumor that develops sporadically and can also be associated with von Hippel-Lindau disease. Hemangioblastomas account for 2-6% of all spinal cord tumors and are ranked third in the structure of intramedullary space-occupying lesions of the spinal ...

Last Updated: 31 Dec 1969

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Suprasellar hemangioblastoma without von Hippel-Lindau disease: a case report and literature review.
 

Author(s): Zhen Li, Tianda Feng, Hao Teng, Yi Hu, Yilong Yao, Yunhui Liu

Journal:

 

Suprasellar hemangioblastoma (HBL) without von Hippel-Lindau (VHL) disease is extremely rare. A 51-year-old woman presented with headache and progressively deteriorating bilateral visual disturbance for 4 months. Magnetic resonance imaging (MRI) revealed a 2.5-cm solid mass in the ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.