Hemangioblastoma

Common Name(s)

Hemangioblastoma

A hemangioblastoma is a benign, highly vascular tumor that can occur in the brain, spinal cord, and retina (the light-sensitive tissue that lines the back of the eye). This tumor accounts for about 2% of brain tumors. As it enlarges, it presses on the brain and can cause neurological symptoms, such as headaches, weakness, sensory loss, balance and coordination problems, and/or hydrocephalus (a buildup of spinal fluid in the brain). Most hemangioblastomas occur sporadically. However, some people develop hemangioblastomas as part of a genetic syndrome called von Hippel-Lindau syndrome. These people usually develop multiple tumors within the brain and spinal cord over their lifetime.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Family Alliance

Dedicated to improving diagnosis, treatment, and life quality for individuals and families affected by von Hippel-Lindau disease and funding research to uncover a cure.

Last Updated: 15 Oct 2012

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioblastoma" for support, advocacy or research.

VHL Family Alliance

Dedicated to improving diagnosis, treatment, and life quality for individuals and families affected by von Hippel-Lindau disease and funding research to uncover a cure.

http://www.vhl.org

Last Updated: 15 Oct 2012

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioblastoma" returned 68 free, full-text research articles on human participants. First 3 results:

Giant solid hemangioblastoma of the cerebellopontine angle: a technically challenging case.
 

Author(s): Bijesh Ravindran Nair, Vivek Joseph, Geeta Chacko, Shyamkumar Nidugala Keshava

Journal: Neurol India. ;62(2):228-9.

 

Last Updated: 14 May 2014

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Sporadic hemangioblastoma of the kidney with PAX2 and focal CD10 expression: report of a case.
 

Author(s): Jin-Gui Jiang, Qiu Rao, Qiu-Yuan Xia, Pin Tu, Zhen-Feng Lu, Qin Shen, Ru-Song Zhang, Bo Yu, Xiao-Jun Zhou, Shan-Shan Shi, Qun-Li Shi

Journal:

 

In this study, we presented an additional case of renal hemangioblastoma, which demonstrates PAX2 and focal CD10 expression. Histologically, the tumor consisted of sheets of oval or polygonal cells and a prominent vascular network. The tumor cells varied in size, and possessed pale ...

Last Updated: 16 Sep 2013

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Scleral penetration of an unusually aggressive case of a retinal hemangioblastoma.
 

Author(s): Murilo Rodrigues, Nicholas T Iliff, Charles G Eberhart, Silvia Montaner, Akrit Sodhi

Journal: Can. J. Ophthalmol.. 2013 Aug;48(4):e67-71.

 

Last Updated: 12 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioblastoma" returned 7 free, full-text review articles on human participants. First 3 results:

Hemangioblastoma of the filum terminale associated with von Hippel-Lindau disease: a case report.
 

Author(s): Bulent Tucer, Mehmet Ali Ekici, Burak Kazanci, Bulent Guclu

Journal: Turk Neurosurg. 2013 ;23(5):672-5.

 

We report a 41-year-old man who presented with low back pain, lower extremity paresthesia, urinary retention and constipation. Magnetic resonance imaging showed a vascular intradural-extramedullary lesion at the second lumbar vertebral level. His medical history revealed that he had ...

Last Updated: 8 Oct 2013

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Intra-extradural dumbbell-shaped hemangioblastoma manifesting as subarachnoid hemorrhage in the cauda equina.
 

Author(s): Yusuke Nishimura, Masahito Hara, Atsushi Natsume, Masaya Takemoto, Ryuichi Fukuyama, Toshihiko Wakabayashi

Journal: Neurol. Med. Chir. (Tokyo). 2012 ;52(9):659-65.

 

A 56-year-old man presented with a rare intra-extradural dumbbell-shaped hemangioblastoma in the lumbar spine associated with von Hippel-Lindau (VHL) disease manifesting as subarachnoid hemorrhage. The tumor, which was exiting at the right L2-3 intervertebral foramen, was removed ...

Last Updated: 25 Sep 2012

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Von Hippel-Lindau disease (VHL): a need for a murine model with retinal hemangioblastoma.
 

Author(s): Stanley Park, Chi-Chao Chan

Journal: Histol. Histopathol.. 2012 Aug;27(8):975-84.

 

Von Hippel-Lindau (VHL) disease is a highly penetrant autosomal dominant systemic malignancy that gives rise to cystic and highly vascularized tumors in a constellation of organs. Patients with VHL disease commonly present with hemangioblastomas in the central nervous system and the ...

Last Updated: 5 Jul 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Psychosocial Consequences of the Screening of Von Hippel Lindau Diseases for Patients Operated for a hémangioblastoma of Nervous Centrasl System
 

Status: Recruiting

Condition Summary: Hemangioblastoma (HB) of the Central Nervous System (CNS)

 

Last Updated: 18 Apr 2014

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Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders
 

Status: Recruiting

Condition Summary: Hemangioblastoma; Hereditary Neoplastic Syndrome; Hippel Lindau Disease; Neoplasm; Renal Cell Carcinoma

 

Last Updated: 20 Jun 2014

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Last Updated: 13 May 2014

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