Hay-Wells Syndrome

Common Name(s)

Hay-Wells Syndrome, Hay-Wells syndrome of ectodermal dysplasia

Hay-Wells syndrome is a form of ectodermal dysplasia, a group of conditions characterized by abnormal development of ectodermal tissues including the skin, hair, nails, teeth, and sweat glands. The most common feature is missing patches of skin (erosions) on the scalp, neck, hands, and feet. The skin erosions can lead to infection, scarring, and hair loss. Other features include changes in skin coloring; misshapen or absent fingernails and toenails; malformed or missing teeth; increased sensitivity to heat; hearing loss; cleft lip and/or palate; and other facial abnormalities. This condition  is caused by mutations in the TP63 gene and is inherited in an autosomal dominant fashion.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hay-Wells Syndrome" for support, advocacy or research.

National Foundation for Ectodermal Dysplasias

The National Foundation for Ectodermal Dysplasias’ mission is to empower and connect people touched by ectodermal dysplasias through education, support, and research.

Last Updated: 7 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hay-Wells Syndrome" for support, advocacy or research.

National Foundation for Ectodermal Dysplasias

The National Foundation for Ectodermal Dysplasias’ mission is to empower and connect people touched by ectodermal dysplasias through education, support, and research.

http://www.nfed.org

Last Updated: 7 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hay-Wells Syndrome" returned 8 free, full-text research articles on human participants. First 3 results:

Syndrome in question. Hay-Wells syndrome.
 

Author(s): Vanessa Mello Tonolli, Hamilton Ometto Stolf, Cláudio Sampieri Tonello, Rafaelle Batistella Pires, Luciana Patricia Fernandes Abbade

Journal: An Bras Dermatol. ;89(2):363-4.

 

Hay-Wells syndrome or AEC (Ankyloblepharon, Ectodermal dysplasia and Cleft lip and palate syndrome) is a rare ectodermal disorder. The treatment is aimed to prevent clinical complications. We describe the case of a four-month old male patient with erosions on the scalp, trunk and ...

Last Updated: 28 Apr 2014

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Renal failure in Hay-Wells syndrome.
 

Author(s): Dhanya Mohan, Dileep K Sugathan, Mohammed Railey, Mona Alrukhaimi

Journal: Saudi J Kidney Dis Transpl. 2013 Nov;24(6):1214-6.

 

Ectodermal dysplasia (ED) is a group of disorders involving developmental defects of the ectodermal structures, with abnormalities in the skin, hair, nails and sweat glands. Ankyloblepharon - ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is ...

Last Updated: 15 Nov 2013

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Hay-Wells syndrome: a case report.
 

Author(s): Dário Júnior de Freitas Rosa, Ronaldo Figueiredo Machado, Marcelino Pereira Martins Neto, Alessandra Almeida Montenegro de Sá, Aloísio Gamonal

Journal: An Bras Dermatol. ;85(2):232-5.

 

Hay-Wells syndrome is a rare form of ectodermal dysplasia initially described by Hay and Wells in 1976. It is an autosomal dominant disorder with varying forms of expression featuring congenital abnormalities of the skin, hair, teeth, nails and sweat glands. The present report describes ...

Last Updated: 3 Jun 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hay-Wells Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.