Hay-Wells Syndrome

Common Name(s)

Hay-Wells Syndrome, Hay-Wells syndrome of ectodermal dysplasia

Hay-Wells syndrome is a form of ectodermal dysplasia, a group of conditions characterized by abnormal development of ectodermal tissues including the skin, hair, nails, teeth, and sweat glands. The most common feature is missing patches of skin (erosions) on the scalp, neck, hands, and feet. The skin erosions can lead to infection, scarring, and hair loss. Other features include changes in skin coloring; misshapen or absent fingernails and toenails; malformed or missing teeth; increased sensitivity to heat; hearing loss; cleft lip and/or palate; and other facial abnormalities. This condition  is caused by mutations in the TP63 gene and is inherited in an autosomal dominant fashion.

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Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hay-Wells Syndrome" for support, advocacy or research.

National Foundation for Ectodermal Dysplasias

The National Foundation for Ectodermal Dysplasias’ mission is to empower and connect people touched by ectodermal dysplasias through education, support, and research.

Last Updated: 12 Feb 2018

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hay-Wells Syndrome" for support, advocacy or research.

National Foundation for Ectodermal Dysplasias

The National Foundation for Ectodermal Dysplasias’ mission is to empower and connect people touched by ectodermal dysplasias through education, support, and research.

http://www.nfed.org

Last Updated: 12 Feb 2018

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
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Recommended Apps

Privately answer questions about your health. Let resources, you select, come to you

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Hay-Wells Syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hay-Wells Syndrome" returned 6 free, full-text research articles on human participants. First 3 results:

Syndrome in question. Hay-Wells syndrome.
 

Author(s): Vanessa Mello Tonolli, Hamilton Ometto Stolf, Cláudio Sampieri Tonello, Rafaelle Batistella Pires, Luciana Patricia Fernandes Abbade

Journal: An Bras Dermatol. ;89(2):363-4.

 

Hay-Wells syndrome or AEC (Ankyloblepharon, Ectodermal dysplasia and Cleft lip and palate syndrome) is a rare ectodermal disorder. The treatment is aimed to prevent clinical complications. We describe the case of a four-month old male patient with erosions on the scalp, trunk and ...

Last Updated: 31 Dec 1969

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Renal failure in Hay-Wells syndrome.
 

Author(s): Dhanya Mohan, Dileep K Sugathan, Mohammed Railey, Mona Alrukhaimi

Journal: Saudi J Kidney Dis Transpl. 2013 Nov;24(6):1214-6.

 

Ectodermal dysplasia (ED) is a group of disorders involving developmental defects of the ectodermal structures, with abnormalities in the skin, hair, nails and sweat glands. Ankyloblepharon - ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is ...

Last Updated: 31 Dec 1969

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Hay-Wells syndrome: a case report.
 

Author(s): Dário Júnior de Freitas Rosa, Ronaldo Figueiredo Machado, Marcelino Pereira Martins Neto, Alessandra Almeida Montenegro de Sá, Aloísio Gamonal

Journal: An Bras Dermatol. ;85(2):232-5.

 

Hay-Wells syndrome is a rare form of ectodermal dysplasia initially described by Hay and Wells in 1976. It is an autosomal dominant disorder with varying forms of expression featuring congenital abnormalities of the skin, hair, teeth, nails and sweat glands. The present report describes ...

Last Updated: 31 Dec 1969

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To view other free, full-text articles on human participants, please click on the link below.

PubMed Article Results at NCBI: 6 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hay-Wells Syndrome" returned 0 free, full-text review articles on human participants.

No free, full-text review articles on human participants are available at this time. Please click this link to visit the PubMed website for results on "Hay-Wells Syndrome".

 
 
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
https://ghr.nlm.nih.gov/condition/ankyloblepharon-ectodermal-defects-cleft-lip-palate-syndrome
https://ghr.nlm.nih.gov/condition/muckle-wells-syndrome
https://ghr.nlm.nih.gov/gene/ST14
https://ghr.nlm.nih.gov/gene/SPINT2
https://ghr.nlm.nih.gov/condition/atopic-dermatitis
https://ghr.nlm.nih.gov/condition/netherton-syndrome
https://ghr.nlm.nih.gov/gene/NLRP3
https://ghr.nlm.nih.gov/condition/22q112-deletion-syndrome
https://ghr.nlm.nih.gov/gene/CC2D2A
https://ghr.nlm.nih.gov/gene/PIGW
https://ghr.nlm.nih.gov/gene/GPD1L
https://ghr.nlm.nih.gov/condition/16p112-deletion-syndrome
https://ghr.nlm.nih.gov/gene/ATP13A2
https://ghr.nlm.nih.gov/gene/RIN2
https://ghr.nlm.nih.gov/gene/ZBTB20
https://ghr.nlm.nih.gov/condition/allergic-asthma
https://ghr.nlm.nih.gov/gene/FLG
https://ghr.nlm.nih.gov/condition/stevens-johnson-syndrome-toxic-epidermal-necrolysis
https://ghr.nlm.nih.gov/condition/kawasaki-disease
https://ghr.nlm.nih.gov/gene/USH2A
Full Results at Genetics Home Reference: 1980 matches
This information is provided by GeneReviews.
http://www.ncbi.nlm.nih.gov/books/NBK43797
This information is provided by Genetic Testing Registry.
http://www.ncbi.nlm.nih.gov/gtr/conditions/C0406709
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.

According to ClinicalTrials.gov there are currently 0 additional "open" studies for "Hay-Wells Syndrome" (open studies are recruiting volunteers) and 0 "Hay-Wells Syndrome" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
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Relief is when you and the right researcher find each other
Finding the right clinical trial for Hay-Wells Syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More