Hantavirus Pulmonary Syndrome

Common Name(s)

Hantavirus Pulmonary Syndrome

Hantavirus pulmonary syndrome (HPS) is a severe, respiratory disease caused by infection with a hantavirus. People can become infected with a hantavirus through contact with hantavirus-infected rodents or their saliva, urine and/or droppings. Early symptoms universally include fatigue, fever and muscle aches (especially in the thighs, hips, and/or back), and sometimes include headaches, dizziness, chills, and abdominal problems such as nausea, vomiting, diarrhea, and pain. Later symptoms of the syndrome occur 4 to 10 days after initial onset and include coughing and shortness of breath. HPS can be fatal; approximately 38% of individuals with HPS do not survive. There is no cure or specific treatment for HPS, but early diagnosis and treatment in intensive care may increase the chance of recovery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hantavirus Pulmonary Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hantavirus Pulmonary Syndrome" returned 106 free, full-text research articles on human participants. First 3 results:

Hantavirus pulmonary syndrome in an Israeli man returning from South America.
 

Author(s): Ori Galante, Ella Abramovich, Anat Nevo-Shor, Yaniv Almog

Journal: Isr. Med. Assoc. J.. 2014 Apr;16(4):259-61.

 

Last Updated: 19 May 2014

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Ribavirin protects Syrian hamsters against lethal hantavirus pulmonary syndrome--after intranasal exposure to Andes virus.
 

Author(s): Monica Ogg, Colleen B Jonsson, Jeremy V Camp, Jay W Hooper

Journal:

 

Andes virus, ANDV, harbored by wild rodents, causes the highly lethal hantavirus pulmonary syndrome (HPS) upon transmission to humans resulting in death in 30% to 50% of the cases. As there is no treatment for this disease, we systematically tested the efficacy of ribavirin in vitro ...

Last Updated: 12 Nov 2013

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Hantavirus pulmonary syndrome outbreak, Brazil, December 2009-January 2010.
 

Author(s): Ana Cláudia Pereira Terças, Marina Atanaka dos Santos, Marta Gislene Pignatti, Mariano Martinez Espinosa, Alba Valéria Gomes de Melo Via, Jaqueline Aparecida Menegatti

Journal: Emerging Infect. Dis.. 2013 Nov;19(11):1824-7.

 

An outbreak of hantavirus pulmonary syndrome occurred in the Sobradinho Indian settlement of the Kayabí ethnic group in northern Mato Grosso during December 2009-January 2010. We conducted a retrospective study to clarify the outbreak's epidemiologic and clinical characteristics. ...

Last Updated: 11 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hantavirus Pulmonary Syndrome" returned 9 free, full-text review articles on human participants. First 3 results:

The role of endothelial activation in dengue hemorrhagic fever and hantavirus pulmonary syndrome.
 

Author(s): Christina F Spiropoulou, Anon Srikiatkhachorn

Journal: Virulence. 2013 Aug;4(6):525-36.

 

The loss of the endothelium barrier and vascular leakage play a central role in the pathogenesis of hemorrhagic fever viruses. This can be caused either directly by the viral infection and damage of the vascular endothelium, or indirectly by a dysregulated immune response resulting ...

Last Updated: 27 Aug 2013

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The Syrian hamster model of hantavirus pulmonary syndrome.
 

Author(s): David Safronetz, Hideki Ebihara, Heinz Feldmann, Jay W Hooper

Journal: Antiviral Res.. 2012 Sep;95(3):282-92.

 

Hantavirus pulmonary syndrome (HPS) is a relatively rare, but frequently fatal disease associated with New World hantaviruses, most commonly Sin Nombre and Andes viruses in North and South America, respectively. It is characterized by fever and the sudden, rapid onset of severe respiratory ...

Last Updated: 22 Aug 2012

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Treatment of hantavirus pulmonary syndrome.
 

Author(s): Colleen B Jonsson, Jay Hooper, Gregory Mertz

Journal: Antiviral Res.. 2008 Apr;78(1):162-9.

 

Viruses in the genus Hantavirus can cause one of two serious illnesses when transmitted from rodents to humans: hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). Of the two diseases, HPS is more severe with an approximate 40% mortality across the ...

Last Updated: 18 Mar 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hantavirus Transmission in Households in Chile
 

Status: Recruiting

Condition Summary: Hantavirus Infections

 

Last Updated: 16 Nov 2011

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Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever
 

Status: Recruiting

Condition Summary: Hemorrhagic Fever With Renal Syndrome

 

Last Updated: 12 Sep 2014

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