Hairy Cell Leukemia

Common Name(s)

Hairy Cell Leukemia

Hairy cell leukemia is a rare, slow-growing cancer of the blood in which the bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. The condition is named after these excess B cells which look 'hairy' under a microscope. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced. The underlying cause of this condition is unknown. While there is no cure, treatment can lead to remission which can last for years.   
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hairy Cell Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hairy Cell Leukemia" returned 271 free, full-text research articles on human participants. First 3 results:

Efficacy of vemurafenib in hairy-cell leukemia.
 

Author(s): Jesvin Samuel, Salvador Macip, Martin J S Dyer

Journal: N. Engl. J. Med.. 2014 Jan;370(3):286-8.

 

Last Updated: 16 Jan 2014

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Hairy cell leukemia--a rare type of leukemia. A retrospective study on 39 patients.
 

Author(s): Amelia Maria Găman

Journal: Rom J Morphol Embryol. 2013 ;54(3):575-9.

 

Hairy cell leukemia (HCL) is a chronic B-cell lymphoid leukemia characterized by pancytopenia, splenomegaly, myelofibrosis and the presence in peripheral blood, bone marrow and spleen of atypical lymphoid cells with a hairy aspect. This is a retrospective analysis of 39 patients hospitalized ...

Last Updated: 26 Sep 2013

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Discrepant results for BRAF V600E mutation among different specimens in a case of hairy cell leukemia.
 

Author(s): Hee-Won Moon, Mina Hur, Sung-Hee Han, Yeo-Min Yun, Sung Yong Kim

Journal: Ann Lab Med. 2013 Jul;33(4):300-3.

 

Last Updated: 4 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hairy Cell Leukemia" returned 11 free, full-text review articles on human participants. First 3 results:

[Recurrent somatic mutation in hairy cell leukemia].
 

Author(s): Eszter Sári, Zsolt Nagy, Judit Demeter

Journal: Orv Hetil. 2013 Jan;154(4):123-7.

 

Hairy cell leukemia is a mature B-cell non-Hogkin lymphoma characterized by unique clinical, morphological and immunhistochemical features. Patients with hairy cell leukemia usually present with splenomegaly, progressive pancytopenia and a relative indolent clinical course. The diagnosis ...

Last Updated: 21 Jan 2013

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Immunoconjugates and new molecular targets in hairy cell leukemia.
 

Author(s): Robert J Kreitman

Journal: Hematology Am Soc Hematol Educ Program. 2012 ;2012():660-6.

 

Hairy cell leukemia (HCL) is a B-cell malignancy that in its classic form is exquisitely sensitive to single-agent purine analog therapy, but that is associated in many patients with late relapse and eventual purine analog resistance. Minimal residual disease, which is present in ...

Last Updated: 12 Dec 2012

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Chemo-immunotherapy for hairy cell leukemia.
 

Author(s): Farhad Ravandi

Journal: Leuk. Lymphoma. 2011 Jun;52 Suppl 2():72-4.

 

With the introduction of the nucleoside analogs cladribine and pentostatin the treatment of patients with hairy cell leukemia (HCL) has been revolutionized, and the majority of patients achieve a long-lasting complete remission with rare patients ever needing the traditional treatment ...

Last Updated: 23 May 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia
 

Status: Recruiting

Condition Summary: Progressive Hairy Cell Leukemia, Initial Treatment; Refractory Hairy Cell Leukemia; Untreated Hairy Cell Leukemia

 

Last Updated: 28 Jul 2014

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Therapy Optimisation for the Treatment of Hairy Cell Leukemia
 

Status: Recruiting

Condition Summary: Hairy Cell Leukemia

 

Last Updated: 2 May 2014

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Cladribine With Simultaneous or Delayed Rituximab to Treat Hairy Cell Leukemia
 

Status: Recruiting

Condition Summary: Hairy Cell Leukemia

 

Last Updated: 30 Apr 2014

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