Haemophilus Influenzae

Common Name(s)

Haemophilus Influenzae

Haemophilus Influenzae is an infectious bacterium that can cause problems for many systems of the body. There are six types (a-f) of the bacterium that can cause serious infections in infants and children under the age of five. The bacteria are passed from person to person through direct contact or respiratory droplets from coughing or sneezing. Haemophilus influenzae are most dangerous when they have infected the bloodstream (bacteremia), lungs (pneumonia), or brain (meningitis). Each of these infections correlates to a different set of symptoms. Haemophilus influenzae infections can be treated with antibiotics. In some severe cases, hospitalization may occur as well.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Haemophilus Influenzae" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Haemophilus Influenzae" returned 1349 free, full-text research articles on human participants. First 3 results:

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure.
 

Author(s): Matteo De Chiara, Derek Hood, Alessandro Muzzi, Derek J Pickard, Tim Perkins, Mariagrazia Pizza, Gordon Dougan, Rino Rappuoli, E Richard Moxon, Marco Soriani, Claudio Donati

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Apr;111(14):5439-44.

 

One of the main hurdles for the development of an effective and broadly protective vaccine against nonencapsulated isolates of Haemophilus influenzae (NTHi) lies in the genetic diversity of the species, which renders extremely difficult the identification of cross-protective candidate ...

Last Updated: 9 Apr 2014

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Prevention and control of haemophilus influenzae type b disease: recommendations of the advisory committee on immunization practices (ACIP).
 

Author(s): Elizabeth C Briere, Lorry Rubin, Pedro L Moro, Amanda Cohn, Thomas Clark, Nancy Messonnier,

Journal: MMWR Recomm Rep. 2014 Feb;63(RR-01):1-14.

 

This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of Haemophilus influenzae type b (Hib) disease in the United States. As a comprehensive summary of previously published recommendations, ...

Last Updated: 27 Feb 2014

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Outer membrane protein P5 is required for resistance of nontypeable Haemophilus influenzae to both the classical and alternative complement pathways.
 

Author(s): Charles V Rosadini, Sanjay Ram, Brian J Akerley

Journal: Infect. Immun.. 2014 Feb;82(2):640-9.

 

The complement system is an important first line of defense against the human pathogen Haemophilus influenzae. To survive and propagate in vivo, H. influenzae has evolved mechanisms for subverting this host defense, most of which have been shown to involve outer surface structures, ...

Last Updated: 30 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Haemophilus Influenzae" returned 41 free, full-text review articles on human participants. First 3 results:

Introduction of Haemophilus influenzae type b (Hib) as pentavalent(DPT-HepB-Hib) vaccine in two states of India.
 

Author(s): Satish Kumar Gupta, Stephen Sosler, Chandrakant Lahariya

Journal: Indian Pediatr. 2012 Sep;49(9):707-9.

 

Last Updated: 1 Oct 2012

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Quorum signaling and sensing by nontypeable Haemophilus influenzae.
 

Author(s): W Edward Swords

Journal:

 

Quorum signals are diffusible factors produced by bacteria that coordinate communal responses. For nontypeable Haemophilus influenzae (NTHi), a series of recent papers indicate that production and sensing of quorum signals are determinants of biofilm formation/maturation and persistence ...

Last Updated: 24 Aug 2012

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Nontypeable Haemophilus influenzae biofilms: role in chronic airway infections.
 

Author(s): W Edward Swords

Journal:

 

Like many pathogens inhabiting mucosal surfaces, nontypeable Haemophilus influenzae (NTHi) forms multicellular biofilm communities both in vitro and in various infection models. In the past 15 years much has been learned about determinants of biofilm formation by this organism and ...

Last Updated: 24 Aug 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Persistency Study After Hib-CRM197 or Hib-TT Vaccines in Chinese Children
 

Status: Not yet recruiting

Condition Summary: Haemophilus Influenzae Type b Invasive Disease; Gram-negative Invasive Infections

 

Last Updated: 25 Aug 2014

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Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Hepatitis B; Haemophilus Influenzae Type B

 

Last Updated: 5 May 2009

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DTaP-IPV-Hep B-PRP~T Combined Vaccine Versus DTaP-IPV//PRP~T Combined Vaccine + Hep B Vaccine in Hep B Primed Infants
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Haemophilus Influenzae Type b Infection; Poliomyelitis; Hepatitis B

 

Last Updated: 25 Mar 2014

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