Haemophilus Influenzae

Common Name(s)

Haemophilus Influenzae

Haemophilus Influenzae is an infectious bacterium that can cause problems for many systems of the body. There are six types (a-f) of the bacterium that can cause serious infections in infants and children under the age of five. The bacteria are passed from person to person through direct contact or respiratory droplets from coughing or sneezing. Haemophilus influenzae are most dangerous when they have infected the bloodstream (bacteremia), lungs (pneumonia), or brain (meningitis). Each of these infections correlates to a different set of symptoms. Haemophilus influenzae infections can be treated with antibiotics. In some severe cases, hospitalization may occur as well.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Haemophilus Influenzae" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Haemophilus Influenzae" returned 1476 free, full-text research articles on human participants. First 3 results:

Evaluation of Haemophilus influenzae type b carrier status among children 10 years after the introduction of Hib vaccine in Brazil.
 

Author(s): Rosemeire Cobo Zanella, Maria Cristina de Cunto Brandileone, Ana Lúcia Andrade, Cinthya Terumi Ogassavara, Cleiton Eduardo Fiório, Angela Pires Brandão, Samanta Cristine Grassi Almeida, Ana Paula Silva Lemos, Maria Cecília Gorla, Telma Regina Carvalhanas, Helena Sato, Bernadete Liphaus, Maria Lígia Nerger, Monica Conde, Ana Freitas Ribeiro

Journal: Mem. Inst. Oswaldo Cruz. 2015 Sep;110(6):755-9.

 

The aim of the present study was to assess the prevalence of Haemophilus influenzae type b (Hib) nasopharyngeal (NP) colonisation among healthy children where Hib vaccination using a 3p+0 dosing schedule has been routinely administered for 10 years with sustained coverage (> 90%). ...

Last Updated: 31 Oct 2015

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[Epidemiological survey of Haemophilus influenzae-positive hospitalized children: a retrospective analysis].
 

Author(s): Jun Hu, Xiao-Lei Wang, Feng Xu, Jiang Xie, Hua-Wei Liu, Li-Li Yang, Yuan-Biao Guo

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 Jun;17(6):596-601.

 

To investigate the basic clinical characteristics and drug resistance of Haemophilus influenzae (Hi) infection in hospitalized children in the past two years.

Last Updated: 25 Jun 2015

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High Pulmonary Levels of IL-6 and IL-1β in Children with Chronic Suppurative Lung Disease Are Associated with Low Systemic IFN-γ Production in Response to Non-Typeable Haemophilus influenzae.
 

Author(s): Susan J Pizzutto, John W Upham, Stephanie T Yerkovich, Anne B Chang

Journal:

 

Non-typeable Haemophilus influenzae (NTHi) is commonly associated with chronic suppurative lung disease in children. We have previously shown that children with chronic suppurative lung disease have a reduced capacity to produce IFN-γ in response to NTHi compared with healthy control ...

Last Updated: 13 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Haemophilus Influenzae" returned 52 free, full-text review articles on human participants. First 3 results:

The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi).
 

Author(s): Paul T King, Roleen Sharma

Journal: J Immunol Res. 2015 ;2015():706376.

 

Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (designated as NTHi) are predominantly ...

Last Updated: 26 Jun 2015

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Vaccines for Nontypeable Haemophilus influenzae: the Future Is Now.
 

Author(s): Timothy F Murphy

Journal: Clin. Vaccine Immunol.. 2015 May;22(5):459-66.

 

Infections due to nontypeable Haemophilus influenzae result in enormous global morbidity in two clinical settings: otitis media in children and respiratory tract infections in adults with chronic obstructive pulmonary disease (COPD). Recurrent otitis media affects up to 20% of children ...

Last Updated: 29 Apr 2015

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Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae.
 

Author(s): Lydia J Finney, Andrew Ritchie, Elizabeth Pollard, Sebastian L Johnston, Patrick Mallia

Journal:

 

Bacterial infection of the lower respiratory tract in chronic obstructive pulmonary disease (COPD) patients is common both in stable patients and during acute exacerbations. The most frequent bacteria detected in COPD patients is Haemophilus influenzae, and it appears this organism ...

Last Updated: 24 Oct 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine,Freeze-dried
 

Status: Recruiting

Condition Summary: Haemophilus Influenzae Type b Infections

 

Last Updated: 24 Sep 2015

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Post-authorization Safety Study of Euforvac-Hib Vaccine for Active Primary Immunization in Infants From 6 Weeks
 

Status: Not yet recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Hepatitis B; Haemophilus Influenza Type B

 

Last Updated: 5 Oct 2014

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Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Hepatitis B; Haemophilus Influenzae Type B

 

Last Updated: 5 May 2009

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