Guillain-Barre Syndrome

Common Name(s)

Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. Symptoms of this disorder include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barre syndrome occurs a few days or weeks after a person has had symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barre syndrome. Most patients recover completely, although some continue to have some degree of weakness.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Guillain-Barre Syndrome" returned 651 free, full-text research articles on human participants. First 3 results:

Guillain-Barré Syndrome (42 Cases) Occurring During a Zika Virus Outbreak in French Polynesia.
 

Author(s): Louise Watrin, Frédéric Ghawché, Philippe Larre, Jean-Philippe Neau, Stéphane Mathis, Emmanuel Fournier

Journal: Medicine (Baltimore). 2016 Apr;95(14):e3257.

 

Zika virus (transmitted by mosquitoes) reached French Polynesia for the first time in 2013, leading to an epidemic affecting 10% of the total population. So far, it has not been known to induce any neurological complications, but, a few weeks after the outbreak, an unexpectedly high ...

Last Updated: 9 Apr 2016

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Distinct Clinical Characteristics of Pediatric Guillain-Barré Syndrome: A Comparative Study between Children and Adults in Northeast China.
 

Author(s): Xiujuan Wu, Donghui Shen, Ting Li, Bing Zhang, Chunrong Li, Mei Mao, Jixue Zhao, Kangding Liu, Hong-Liang Zhang

Journal:

 

Clinical characteristics of pediatric Guillain-Barré syndrome (GBS) have been extensively studied whereas scarcely been compared with those of adult GBS. Herein we compared the clinical features of GBS between pediatric and adult patients.

Last Updated: 15 Mar 2016

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Zika virus detection in urine from patients with Guillain-Barré syndrome on Martinique, January 2016.
 

Author(s): Benoît Rozé, Fatiha Najioullah, Jean-Louis Fergé, Kossivi Apetse, Yannick Brouste, Raymond Cesaire, Cédric Fagour, Laurence Fagour, Patrick Hochedez, Séverine Jeannin, Julien Joux, Hossein Mehdaoui, Ruddy Valentino, Aïssatou Signate, André Cabié,

Journal: Euro Surveill.. 2016 ;21(9):.

 

We report two cases of Guillain-Barré syndrome who had concomitant Zika virus viruria. This viruria persisted for longer than 15 days after symptom onset. The cases occurred on Martinique in January 2016, at the beginning of the Zika virus outbreak. Awareness of this possible neurological ...

Last Updated: 12 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Guillain-Barre Syndrome" returned 54 free, full-text review articles on human participants. First 3 results:

Guillain-Barre syndrome following dengue fever and literature review.
 

Author(s): Dissanayake Mudiyanselage Priyantha Udaya Kumara Ralapanawa, Senanayake Abeysinghe Mudiyanselage Kularatne, Widana Arachilage Thilak Ananda Jayalath

Journal:

 

Dengue is an arboviral infection that classically presents with fever, joint pain, headaches, skin flush and morbilliform rashes. The incidence of neurological symptoms and complications in dengue varies from 1 to 25% that include encephalopathy, Guillain-Barre syndrome (GBS), acute ...

Last Updated: 28 Nov 2015

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Biomarkers of Guillain-Barré Syndrome: Some Recent Progress, More Still to Be Explored.
 

Author(s): Ying Wang, Shuang Sun, Jie Zhu, Li Cui, Hong-Liang Zhang

Journal: Mediators Inflamm.. 2015 ;2015():564098.

 

Guillain-Barré syndrome (GBS), the axonal subtype of which is mainly triggered by C. jejuni with ganglioside-mimicking lipooligosaccharides (LOS), is an immune-mediated disorder in the peripheral nervous system (PNS) accompanied by the disruption of the blood-nerve barrier (BNB) ...

Last Updated: 9 Oct 2015

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Human Leukocyte Antigen DQB1 (HLA-DQB1) Polymorphisms and the Risk for Guillain-Barré Syndrome: A Systematic Review and Meta-Analysis.
 

Author(s): Peng-Peng Jin, Li-Li Sun, Bo-Jun Ding, Na Qin, Bin Zhou, Feng Xia, Li Li, Li-Juan Liu, Xue-Dong Liu, Gang Zhao, Wen Wang, Yan-Chun Deng, Shuang-Xing Hou

Journal:

 

Guillain-Barré syndrome (GBS) is an autoimmune disorder of the peripheral nervous system. There is no consensus regarding reported associations between human leukocyte antigen DQB1 (HLA-DQB1) polymorphisms and the risk for developing GBS. Here, we evaluated possible associations ...

Last Updated: 24 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

sCD163 as a Potential Biomarker in Guillain- Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barre Syndrome

 

Last Updated: 21 Oct 2015

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Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome

 

Last Updated: 6 Oct 2016

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International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 2 Mar 2015

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