Guillain-Barre Syndrome

Common Name(s)

Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. Symptoms of this disorder include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barre syndrome occurs a few days or weeks after a person has had symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barre syndrome. Most patients recover completely, although some continue to have some degree of weakness.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Guillain-Barre Syndrome" returned 626 free, full-text research articles on human participants. First 3 results:

Last Updated: 20 Nov 2015

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Short-Term Prognosis of Mechanically Ventilated Patients With Guillain-Barré Syndrome Is Worsened by Corticosteroids as an Add-On Therapy.
 

Author(s): Xiujuan Wu, Bing Zhang, Chunrong Li, Donghui Shen, Kangding Liu, Jie Zhu, Hong-Liang Zhang

Journal: Medicine (Baltimore). 2015 Oct;94(43):e1898.

 

Intravenous immunoglobulin (IVIg) has been proven most effective in treating Guillain-Barré syndrome (GBS). Corticosteroids as an add-on therapy have been prescribed in severe GBS cases. However, the efficacy of intravenous corticosteroids combined with IVIg in dealing with severe ...

Last Updated: 30 Oct 2015

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Is a second cycle of immunoglobulin justified in axonal forms of Guillain-Barré syndrome?
 

Author(s): Daniel Agustin Godoy, Alejandro Rabinstein

Journal: Arq Neuropsiquiatr. 2015 Oct;73(10):848-51.

 

Objective In certain situations, severe forms of Guillain-Barré syndrome (GBS) show no response or continue to deteriorate after intravenous immunoglobulin (IVIg) infusion. It is unclear what the best treatment option would be in these circumstances.Method This is a case report on ...

Last Updated: 15 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Guillain-Barre Syndrome" returned 50 free, full-text review articles on human participants. First 3 results:

[Neurogenic osteoarthritis in Guillain Barre syndrome: a rare complication (case report and review of the literature)].
 

Author(s): Hatim Abid, Mohamed El Idrissi, Mohamed Shimi, Abdelhalim El Ibrahimi, Abdelmajid El Mrini

Journal:

 

Last Updated: 10 Jul 2015

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Dysgeusia in a Patient with Guillain-Barré Syndrome Associated with Acute Hepatitis E: A Case Report and Literature Review.
 

Author(s): Masa-Aki Higuchi, Jiro Fukae, Jun Tsugawa, Shinji Ouma, Kazuaki Takahashi, Shunji Mishiro, Yoshio Tsuboi

Journal: Intern. Med.. 2015 ;54(12):1543-6.

 

Guillain-Barré syndrome (GBS) is usually triggered by viral or bacterial infection. In addition, it was recently reported that infection with hepatitis E virus (HEV) also causes GBS. A 49-year-old man presented with acute-onset paralysis in all extremities and dysgeusia during an ...

Last Updated: 15 Jun 2015

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Role of cytokines and Toll-like receptors in the immunopathogenesis of Guillain-Barré syndrome.
 

Author(s): Kishan Kumar Nyati, Kashi Nath Prasad

Journal: Mediators Inflamm.. 2014 ;2014():758639.

 

Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system, mostly triggered by an aberrant immune response to an infectious pathogen. Although several infections have been implicated in the pathogenesis of GBS, not all such infected individuals develop ...

Last Updated: 23 Jan 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 2 Mar 2015

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sCD163 as a Potential Biomarker in Guillain- Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barre Syndrome

 

Last Updated: 21 Oct 2015

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Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barre Syndrome; Constipation

 

Last Updated: 28 May 2015

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