Guillain-Barre Syndrome

Common Name(s)

Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. Symptoms of this disorder include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barre syndrome occurs a few days or weeks after a person has had symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barre syndrome. Most patients recover completely, although some continue to have some degree of weakness.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Guillain-Barre Syndrome" returned 642 free, full-text research articles on human participants. First 3 results:

Guillain-Barré Syndrome Associated with Zika Virus Infection in Colombia.
 

Author(s): Beatriz Parra, Jairo Lizarazo, Jorge A Jiménez-Arango, Andrés F Zea-Vera, Guillermo González-Manrique, José Vargas, Jorge A Angarita, Gonzalo Zuñiga, Reydmar Lopez-Gonzalez, Cindy L Beltran, Karen H Rizcala, Maria T Morales, Oscar Pacheco, Martha L Ospina, Anupama Kumar, David R Cornblath, Laura S Muñoz, Lyda Osorio, Paula Barreras, Carlos A Pardo

Journal: N. Engl. J. Med.. 2016 Oct;375(16):1513-1523.

 

Background Zika virus (ZIKV) infection has been linked to the Guillain-Barré syndrome. From November 2015 through March 2016, clusters of cases of the Guillain-Barré syndrome were observed during the outbreak of ZIKV infection in Colombia. We characterized the clinical features ...

Last Updated: 5 Oct 2016

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Zika Virus and the Guillain-Barré Syndrome - Case Series from Seven Countries.
 

Author(s): Thais Dos Santos, Angel Rodriguez, Maria Almiron, Antonio Sanhueza, Pilar Ramon, Wanderson K de Oliveira, Giovanini E Coelho, Roberto Badaró, Juan Cortez, Martha Ospina, Raquel Pimentel, Rolando Masis, Franklin Hernandez, Bredy Lara, Romeo Montoya, Beatrix Jubithana, Angel Melchor, Angel Alvarez, Sylvain Aldighieri, Christopher Dye, Marcos A Espinal

Journal: N. Engl. J. Med.. 2016 Oct;375(16):1598-1601.

 

Last Updated: 31 Aug 2016

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An unusual case of recurrent Guillain-Barré syndrome with normal cerebrospinal fluid protein levels: a case report.
 

Author(s): Sonali Sihindi Chapa Gunatilake, Rohitha Gamlath, Harith Wimalaratna

Journal:

 

Guillain-Barré syndrome is an acquired polyradiculo-neuropathy, often preceded by an antecedent event. It is a monophasic disease but a recurrence rate of 1-6 % is documented in a subset group of patients. Patients with Guillain-Barré syndrome show cerebrospinal fluid albuminocytologic ...

Last Updated: 6 Sep 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Guillain-Barre Syndrome" returned 52 free, full-text review articles on human participants. First 3 results:

Guillain-Barré syndrome associated with the Zika virus outbreak in Brazil.
 

Author(s): Lucas Masiêro Araujo, Maria Lucia Brito Ferreira, Osvaldo Jm Nascimento

Journal: Arq Neuropsiquiatr. 2016 Mar;74(3):253-5.

 

Zika virus (ZIKV) is now considered an emerging flavivirosis, with a first large outbreak registered in the Yap Islands in 2007. In 2013, a new outbreak was reported in the French Polynesia, with associated cases of neurological complications including Guillain-Barré syndrome (GBS). ...

Last Updated: 7 Apr 2016

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Guillain-Barre syndrome following dengue fever and literature review.
 

Author(s): Dissanayake Mudiyanselage Priyantha Udaya Kumara Ralapanawa, Senanayake Abeysinghe Mudiyanselage Kularatne, Widana Arachilage Thilak Ananda Jayalath

Journal:

 

Dengue is an arboviral infection that classically presents with fever, joint pain, headaches, skin flush and morbilliform rashes. The incidence of neurological symptoms and complications in dengue varies from 1 to 25% that include encephalopathy, Guillain-Barre syndrome (GBS), acute ...

Last Updated: 28 Nov 2015

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Biomarkers of Guillain-Barré Syndrome: Some Recent Progress, More Still to Be Explored.
 

Author(s): Ying Wang, Shuang Sun, Jie Zhu, Li Cui, Hong-Liang Zhang

Journal: Mediators Inflamm.. 2015 ;2015():564098.

 

Guillain-Barré syndrome (GBS), the axonal subtype of which is mainly triggered by C. jejuni with ganglioside-mimicking lipooligosaccharides (LOS), is an immune-mediated disorder in the peripheral nervous system (PNS) accompanied by the disruption of the blood-nerve barrier (BNB) ...

Last Updated: 9 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

sCD163 as a Potential Biomarker in Guillain- Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barre Syndrome

 

Last Updated: 21 Oct 2015

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Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome

 

Last Updated: 6 Oct 2016

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International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 4 Jan 2017

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