Guillain-Barre Syndrome

Common Name(s)

Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. Symptoms of this disorder include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barre syndrome occurs a few days or weeks after a person has had symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barre syndrome. Most patients recover completely, although some continue to have some degree of weakness.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Guillain-Barre Syndrome" returned 535 free, full-text research articles on human participants. First 3 results:

Zika virus infection complicated by Guillain-Barre syndrome--case report, French Polynesia, December 2013.
 

Author(s): E Oehler, L Watrin, P Larre, I Leparc-Goffart, S Lastere, F Valour, L Baudouin, Hp Mallet, D Musso, F Ghawche

Journal:

 

Zika fever, considered as an emerging disease of arboviral origin, because of its expanding geographic area, is known as a benign infection usually presenting as an influenza-like illness with cutaneous rash. So far, Zika virus infection has never led to hospitalisation. We describe ...

Last Updated: 14 Mar 2014

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A rare case of Guillain-Barre syndrome following scrub typhus.
 

Author(s): Vishal M Sawale, Sanjay Upreti, Th Suraj Singh, N Biplab Singh, Th Bhimo Singh

Journal: Neurol India. ;62(1):82-3.

 

Last Updated: 10 Mar 2014

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Guillain Barre syndrome in an HIV-1-infected patient after the beginning of combined antiretroviral therapy: an immune reconstitution inflammatory syndrome?
 

Author(s): Alessandra Fantauzzi, Maria Anna Digiulio, Eugenio Nelson Cavallari, Gabriella d'Ettorre, Vincenzo Vullo, Ivano Mezzaroma

Journal: New Microbiol.. 2014 Jan;37(1):103-7.

 

HIV-1-associated Guillan-Barre syndrome (hGBS) is an ascendant progressive polyradiculoneuropathy described throughout the course of the viral disease, mainly associated with the acute retroviral syndrome. HGBS is occasionally described in severely immunocompromised subjects in the ...

Last Updated: 17 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Guillain-Barre Syndrome" returned 41 free, full-text review articles on human participants. First 3 results:

Role of Campylobacter jejuni infection in the pathogenesis of Guillain-Barré syndrome: an update.
 

Author(s): Kishan Kumar Nyati, Roopanshi Nyati

Journal: Biomed Res Int. 2013 ;2013():852195.

 

Our current knowledge on Campylobacter jejuni infections in humans has progressively increased over the past few decades. Infection with C. jejuni is the most common cause of bacterial gastroenteritis, sometimes surpassing other infections due to Salmonella, Shigella, and Escherichia ...

Last Updated: 3 Sep 2013

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Guillain-Barré syndrome and variants.
 

Author(s): Mazen M Dimachkie, Richard J Barohn

Journal: Neurol Clin. 2013 May;31(2):491-510.

 

Guillain-Barré syndrome (GBS) is characterized by rapidly evolving ascending weakness, mild sensory loss, and hyporeflexia or areflexia. Acute inflammatory demyelinating polyneuropathy was the first to be recognized over a century ago and is the most common form of GBS. Axonal motor ...

Last Updated: 6 May 2013

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The role of chemokines in Guillain-Barré syndrome.
 

Author(s): Sharon Chiang, Eroboghene E Ubogu

Journal: Muscle Nerve. 2013 Sep;48(3):320-30.

 

Chemokines and their receptors are important mediators of inflammation. Guillain-Barré syndrome (GBS) is the most common cause of acute paralysis worldwide. Despite current treatments, outcomes are suboptimal. Specific chemokine receptor antagonists have the potential to be efficacious ...

Last Updated: 16 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 26 Nov 2013

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Last Updated: 29 Nov 2005

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Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome

 

Last Updated: 19 Aug 2014

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