Guillain-Barre Syndrome

Common Name(s)

Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. Symptoms of this disorder include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barre syndrome occurs a few days or weeks after a person has had symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barre syndrome. Most patients recover completely, although some continue to have some degree of weakness.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Guillain-Barre Syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Guillain-Barre Syndrome" returned 540 free, full-text research articles on human participants. First 3 results:

Guillain-Barré syndrome presenting with Raynaud's phenomenon: a case report.
 

Author(s): Sonali Sihindi Chapa Gunatilake, Harith Wimalaratna

Journal:

 

Guillain-Barré syndrome is an immune mediated acute inflammatory polyradiculo-neuropathy involving the peripheral nervous system. Commonest presentation is acute or subacute flaccid ascending paralysis of limbs. Rarely autonomic dysfunction can be the presenting feature of Guillain-Barré ...

Last Updated: 11 Sep 2014

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Retrospective analysis of Guillain-Barré syndrome and Fisher syndrome after the Great East Japan Earthquake.
 

Author(s): Hirofumi Tsuboi, Naoto Sugeno, Maki Tateyama, Ichiro Nakashima, Takafumi Hasegawa, Hiroshi Kuroda, Kimihiko Kaneko, Michiko Kobayashi, Aya Ishigaki, Juichi Fujimori, Masashi Aoki

Journal: Brain Behav. 2014 Jul;4(4):595-7.

 

Guillain-Barré syndrome (GBS) and Fisher syndrome (FS) are immune-mediated peripheral neuropathies, and most of these cases were known to be associated with a preceding infection. Recent reports evidenced an increase in the number of infectious disease cases after the earthquake. ...

Last Updated: 27 Aug 2014

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Syndrome of inappropriate antidiuretic hormone secretion related to Guillain-Barré syndrome after laparoscopic cholecystectomy.
 

Author(s): Mensure Yılmaz Çakırgöz, Esra Duran, Cem Topuz, Deniz Kara, Namigar Turgut, Ülkü Aygen Türkmen, Bülent Turanç, Mustafa Önder Dolap, Volkan Hancı

Journal: Braz J Anesthesiol. ;64(3):195-8.

 

Guillain-Barré Syndrome is one of the most common causes of acute polyneuropathy in adults. Recently, the occurrence of Guillain-Barré Syndrome after major and minor surgical operations has been increasingly debated. In Guillain-Barré syndrome, syndrome of inappropriate antidiuretic ...

Last Updated: 9 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Guillain-Barre Syndrome" returned 42 free, full-text review articles on human participants. First 3 results:

[Guillain-Barre syndrome after allogeneic hematopoietic stem cell transplantation: two cases report and literature review].
 

Author(s): Xiaoqian Xu, Lin Jia, Li Chen, Weiping Zhang, Jianmin Wang

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Aug;35(8):694-7.

 

To investigate the clinical characteristics, treatment and prognosis of Guillain-Barre syndrome (GBS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Last Updated: 25 Aug 2014

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Guillain-Barre syndrome, influenza, and influenza vaccination: the epidemiologic evidence.
 

Author(s): Claudia Vellozzi, Shahed Iqbal, Karen Broder

Journal: Clin. Infect. Dis.. 2014 Apr;58(8):1149-55.

 

Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide, and is thought to be immune-mediated. It is preceded by upper respiratory or gastrointestinal infection in about two-thirds of cases and is associated with some viral infections, including ...

Last Updated: 28 Mar 2014

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Role of Campylobacter jejuni infection in the pathogenesis of Guillain-Barré syndrome: an update.
 

Author(s): Kishan Kumar Nyati, Roopanshi Nyati

Journal: Biomed Res Int. 2013 ;2013():852195.

 

Our current knowledge on Campylobacter jejuni infections in humans has progressively increased over the past few decades. Infection with C. jejuni is the most common cause of bacterial gastroenteritis, sometimes surpassing other infections due to Salmonella, Shigella, and Escherichia ...

Last Updated: 3 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 2 Mar 2015

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Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome

 

Last Updated: 14 Jan 2015

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Last Updated: 29 Nov 2005

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