Graves' Disease

Common Name(s)

Graves' Disease, Graves Disease

Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism). It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism and occurs most often in women over age 20. However, the disorder may occur at any age and may affect males as well.  Treatment may include radioiodine therapy, antithyroid drugs, and/or thyroid surgery.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Graves' Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

Last Updated: 12 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Graves' Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

http://www.gdatf.org

Last Updated: 12 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Graves' Disease" returned 564 free, full-text research articles on human participants. First 3 results:

Metastatic papillary carcinoma of the thyroid in a patient previously treated for Graves' disease.
 

Author(s): Garba H Yunusa, Tessa Kotze, Anita Brink

Journal: Ann Afr Med. ;13(2):91-4.

 

Incidental papillary carcinoma of the thyroid in patients treated surgically for benign thyroid diseases including Graves' disease is a known phenomenon. However, the management of these patients remains an issue of concern and controversy for those who care for them. We report a ...

Last Updated: 7 Apr 2014

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The unusual association of Graves' disease, chronic spontaneous urticaria, and premature ovarian failure: report of a case and HLA haplotype characterization.
 

Author(s): Rosaria Maddalena Ruggeri, Giuseppe Vita, Anna Grazia D'Angelo, Paolina Quattrocchi, Rosaria Certo, Salvatore Benvenga, Salvatore Cannavò, Sebastiano Gangemi

Journal: Arq Bras Endocrinol Metabol. 2013 Dec;57(9):748-52.

 

Chronic spontaneous urticaria (CSU), defined as the occurrence of spontaneous wheals for more than six weeks, has been associated with autoimmune diseases. Herein, we report the unusual association of CSU, Graves' disease, and premature ovarian failure. Human leukocyte antigen (HLA) ...

Last Updated: 9 Jan 2014

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Palmar vitiligo associated with Graves' disease.
 

Author(s): Yosuke Sasaki, Mitsuyo Kinjo, Rita Lynn McGill, Hitoshi Miyasato

Journal: Intern. Med.. 2013 ;52(17):2001-2.

 

Last Updated: 2 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Graves' Disease" returned 36 free, full-text review articles on human participants. First 3 results:

[Selenium in Graves' disease].
 

Author(s): Jadwiga Kryczyk, Paweł Zagrodzki

Journal:

 

The aim of this study was to present the current state of knowledge of the role of selenium in Graves' disease. Recently, in the pathogenesis and course of this autoimmune disease, more attention has been paid to the relationship between oxidative stress and the antioxidant system, ...

Last Updated: 11 Jun 2013

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[Treatment of hyperthyroidism due to Graves' disease: what is the recommended antithyroid drug during pregnancy?].
 

Author(s): P Caron

Journal: J Gynecol Obstet Biol Reprod (Paris). 2013 May;42(3):232-7.

 

Clinical hyperthyroidism during the first trimester of pregnancy due to Graves' disease can be associated with maternal, obstetrical and fetal complications, indicating an active treatment to restore normal thyroid function. Antithyroid drugs are the first line treatment in pregnant ...

Last Updated: 1 May 2013

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Mechanisms in endocrinology. Role of emotional stress in the pathophysiology of Graves' disease.
 

Author(s): Géraldine Falgarone, Hassan M Heshmati, Régis Cohen, Gérard Reach

Journal:

 

The role of stress in the pathophysiology of Graves' disease is suggested by several clinical observations, by recent advances in immunology and by better understanding of autoimmune diseases which provides new insights into potential effects of stress hormones on T helper cell imbalance ...

Last Updated: 11 Dec 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Shared Decision Making in Graves Disease - Graves Disease (GD) Choice
 

Status: Recruiting

Condition Summary: Graves' Disease; Thyroid Disease; Hyperthyroidism

 

Last Updated: 4 Apr 2014

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Comparative Study of Different I-131 Doses in Graves' Disease
 

Status: Recruiting

Condition Summary: Graves' Disease

 

Last Updated: 14 Apr 2014

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Radioactive Iodide Therapy for Pediatric Graves' Disease
 

Status: Recruiting

Condition Summary: Graves' Disease

 

Last Updated: 15 Jul 2014

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