Alopecia Areata

Common Name(s)

Alopecia Areata

Alopecia areata (AA) is an autoimmune disease in which the immune system mistakenly attacks the hair follicles. In most cases, hair falls out in small, round patches on the scalp. Although uncommon, hair loss can be more extensive in some people and affect other parts of the body. This condition can progress to complete loss of scalp hair (alopecia totalis) or total loss of all body hair (alopecia universalis).  Although the exact cause of AA is unknown, roughly 20% of affected people have a family member with alopecia, suggesting that genetic factors may contribute to the development of the condition. There is no cure or approved therapy for AA; however, some people find that medications approved for other purposes can help regrow hair.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

Last Updated: 14 Aug 2014

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Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

Last Updated: 20 Mar 2013

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National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

Last Updated: 8 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

http://www.baldgirlsdolunch.org

Last Updated: 14 Aug 2014

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Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

http://www.childrensalopeciaproject.org

Last Updated: 20 Mar 2013

View Details
National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

http://www.naaf.org

Last Updated: 8 Mar 2013

View Details

 

General Support Organizations

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General Resources

How Are You Nurturing Your Self Image

Patient-focused education for women with alopecia diagnoses.

Updated 14 Aug 2014

Open Doc
Understanding the Lives of Women with Alopecia Areata

Public awareness and patient-focused Infographic suitable for printing

Updated 14 Aug 2014

Open Doc
Video: Bald Girls Do Lunch (NYC)

"Spring in the City": Bald Girls Do Lunch Founder Thea Chassin hosts a BGDL evening in New York City

Updated 14 Aug 2014

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VIDEO: BGDL on the TODAY SHOW

The TODAY show came on location with Thea Chassin and Bald Girls Do Lunch in Illinois

Updated 14 Aug 2014

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National Public Radio on location with BGDL

NPR producer Patrick Skahill interviews Thea Chassin on location at Bald Girls Do Lunch in Connecticut.

Updated 14 Aug 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alopecia Areata" returned 215 free, full-text research articles on human participants. First 3 results:

High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease.
 

Author(s): Romana Čeović, Lana Desnica, Dražen Pulanić, Ranka Serventi Seiwerth, Ivana Ilić, Magdalena Grce, Marinka Mravak Stipetić, Tajana Klepac Pulanić, Ervina Bilić, Ernest Bilić, Milan Milošević, Radovan Vrhovac, Damir Nemet, Steven Z Pavletic

Journal: Croat. Med. J.. 2016 Jun;57(3):229-38.

 

To determine the frequency and the characteristics of cutaneous manifestations, especially vitiligo and alopecia areata, in patients with chronic graft-vs-host disease (cGVHD).

Last Updated: 4 Jul 2016

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Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not of Plaque Psoriasis with Tofacitinib in a Young Woman.
 

Author(s): Ulrich Mrowietz, Sascha Gerdes, Regine Gläser, Oltmann Schröder

Journal: Acta Derm. Venereol.. 2017 Feb;97(2):283-284.

 

is missing (Short communication).

Last Updated: 28 Jun 2016

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Molecular signatures define alopecia areata subtypes and transcriptional biomarkers.
 

Author(s): Ali Jabbari, Jane E Cerise, James C Chen, Julian Mackay-Wiggan, Madeleine Duvic, Vera Price, Maria Hordinsky, David Norris, Raphael Clynes, Angela M Christiano

Journal: EBioMedicine. 2016 May;7():240-7.

 

Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss with a variable clinical course. In this study, we conducted whole genome gene expression analysis of 96 human scalp skin biopsy specimens from AA or normal control subjects. Based on gene expression profiling, ...

Last Updated: 21 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alopecia Areata" returned 41 free, full-text review articles on human participants. First 3 results:

Psychological and psychopathological factors in alopecia areata.
 

Author(s): Marta Kuty-Pachecka

Journal: Psychiatr. Pol.. 2015 ;49(5):955-64.

 

The problems of mental disorders and psychological aspects in the condition referred to as alopecia areata in the Polish context are not well researched yet. The objective of our analyses is to present the results of the review of literature devoted to the occurrence of mental disorders ...

Last Updated: 21 Dec 2015

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Industry Perspective on Alopecia Areata.
 

Author(s): Amanda T Wagner

Journal: J. Investig. Dermatol. Symp. Proc.. 2015 Nov;17(2):67-9.

 

Recent advances in our understanding of the autoimmune basis of alopecia areata provide an opportunity to create novel effective pharmaceutical interventions. The current lack of approved therapies for alopecia areata presents a high unmet medical need, as well as a potentially attractive ...

Last Updated: 10 Nov 2015

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Development of Uniform Protocol for Alopecia Areata Clinical Trials.
 

Author(s): James A Solomon

Journal: J. Investig. Dermatol. Symp. Proc.. 2015 Nov;17(2):63-6.

 

Developing a successful treatment for alopecia areata (AA), clearly has not been at the forefront of the agenda for new drug/device development among the pharmaceutical and medical device industry. The National Alopecia Areata Foundation (NAAF), a patient advocacy group, initiated ...

Last Updated: 10 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Aug 2016

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Topical Garlic Concentrate for Alopecia Areata in Children
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 19 Feb 2016

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Excimer Light for Alopecia Areata
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 30 Jun 2015

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