Alopecia Areata

Common Name(s)

Alopecia Areata

Alopecia areata (AA) is an autoimmune disease in which the immune system mistakenly attacks the hair follicles. In most cases, hair falls out in small, round patches on the scalp. Although uncommon, hair loss can be more extensive in some people and affect other parts of the body. This condition can progress to complete loss of scalp hair (alopecia totalis) or total loss of all body hair (alopecia universalis).  Although the exact cause of AA is unknown, roughly 20% of affected people have a family member with alopecia, suggesting that genetic factors may contribute to the development of the condition. There is no cure or approved therapy for AA; however, some people find that medications approved for other purposes can help regrow hair.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

Last Updated: 14 Aug 2014

View Details
Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

Last Updated: 20 Mar 2013

View Details
National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

Last Updated: 8 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

http://www.baldgirlsdolunch.org

Last Updated: 14 Aug 2014

View Details
Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

http://www.childrensalopeciaproject.org

Last Updated: 20 Mar 2013

View Details
National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

http://www.naaf.org

Last Updated: 8 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

How Are You Nurturing Your Self Image

Patient-focused education for women with alopecia diagnoses.

Updated 14 Aug 2014

Open Doc
Understanding the Lives of Women with Alopecia Areata

Public awareness and patient-focused Infographic suitable for printing

Updated 14 Aug 2014

Open Doc
Video: Bald Girls Do Lunch (NYC)

"Spring in the City": Bald Girls Do Lunch Founder Thea Chassin hosts a BGDL evening in New York City

Updated 14 Aug 2014

Go To URL
VIDEO: BGDL on the TODAY SHOW

The TODAY show came on location with Thea Chassin and Bald Girls Do Lunch in Illinois

Updated 14 Aug 2014

Go To URL
National Public Radio on location with BGDL

NPR producer Patrick Skahill interviews Thea Chassin on location at Bald Girls Do Lunch in Connecticut.

Updated 14 Aug 2014

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alopecia Areata" returned 208 free, full-text research articles on human participants. First 3 results:

Late-onset alopecia areata: descriptive analysis of 30 cases.
 

Author(s): Rosana Lazzarini, Camila Bilac Oliari, Ana Luisa Nasser Erthal

Journal: An Bras Dermatol. ;91(6):844-845.

 

Alopecia areata is an autoimmune disease characterized by non-scaring hair loss. The onset in over 50-year-old patients is rare and has barely been studied. Cases of this disease have been retrospectively analyzed - according to clinical forms, extension, and associated diseases - ...

Last Updated: 18 Jan 2017

Go To URL
Lack of association between alopecia areata and HLA class I and II in a southeastern Brazilian population.
 

Author(s): Ângela Marques Barbosa, Luiz Euribel Prestes-Carneiro, Aldri Roberta Sodoschi Sobral, Marcelo Jun Sakiyama, Bruna Cerávolo Lemos, Marilda Aparecida Milanez Morgado de Abreu, Luciana Leite Crivelin Martos, Ricardo Alberto Moliterno

Journal: An Bras Dermatol. ;91(3):284-9.

 

Alopecia areata (AA) is a common disorder of unknown etiology that affects approximately 0.7% to 3.8% of patients among the general population. Currently, genetic and autoimmune factors are emphasized as etiopathogenic. Studies linking Human Leukocyte Antigens (HLA) to AA have suggested ...

Last Updated: 21 Jul 2016

Go To URL
High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease.
 

Author(s): Romana Čeović, Lana Desnica, Dražen Pulanić, Ranka Serventi Seiwerth, Ivana Ilić, Magdalena Grce, Marinka Mravak Stipetić, Tajana Klepac Pulanić, Ervina Bilić, Ernest Bilić, Milan Milošević, Radovan Vrhovac, Damir Nemet, Steven Z Pavletic

Journal: Croat. Med. J.. 2016 Jun;57(3):229-38.

 

To determine the frequency and the characteristics of cutaneous manifestations, especially vitiligo and alopecia areata, in patients with chronic graft-vs-host disease (cGVHD).

Last Updated: 4 Jul 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alopecia Areata" returned 41 free, full-text review articles on human participants. First 3 results:

Alopecia areata in patients with inflammatory bowel disease: an overview.
 

Author(s): Aleksandra Sobolewska-Włodarczyk, Marcin Włodarczyk, Jakub Fichna, Maria Wiśniewska-Jarosińska

Journal: Folia Med Cracov. ;56(1):5-12.

 

Alopecia areata (AA) is one of the most common causes of non-scarring hair loss, which is associated with the premature induction of hair follicle regression. The pathogenesis of AA is unknown, although it is believed that a complicated autoimmune mechanism with Th1 lymphocytes and ...

Last Updated: 12 Aug 2016

Go To URL
Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies.
 

Author(s): Amos Gilhar, Adam G Schrum, Amos Etzioni, Herman Waldmann, Ralf Paus

Journal: Autoimmun Rev. 2016 Jul;15(7):726-35.

 

One of the most common human autoimmune diseases, alopecia areata (AA), is characterized by sudden, often persisting and psychologically devastating hair loss. Animal models have helped greatly to elucidate critical cellular and molecular immune pathways in AA. The two most prominent ...

Last Updated: 21 May 2016

Go To URL
Psychological and psychopathological factors in alopecia areata.
 

Author(s): Marta Kuty-Pachecka

Journal: Psychiatr. Pol.. 2015 ;49(5):955-64.

 

The problems of mental disorders and psychological aspects in the condition referred to as alopecia areata in the Polish context are not well researched yet. The objective of our analyses is to present the results of the review of literature devoted to the occurrence of mental disorders ...

Last Updated: 21 Dec 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Topical Garlic Concentrate for Alopecia Areata in Children
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 19 Feb 2016

Go to URL
A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia Areata
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 11 Apr 2017

Go to URL
Intralesional Steroids in the Treatment of Alopecia Areata
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 27 Oct 2016

Go to URL