Alopecia Areata

Common Name(s)

Alopecia Areata

Alopecia areata (AA) is an autoimmune disease in which the immune system mistakenly attacks the hair follicles. In most cases, hair falls out in small, round patches on the scalp. Although uncommon, hair loss can be more extensive in some people and affect other parts of the body. This condition can progress to complete loss of scalp hair (alopecia totalis) or total loss of all body hair (alopecia universalis).  Although the exact cause of AA is unknown, roughly 20% of affected people have a family member with alopecia, suggesting that genetic factors may contribute to the development of the condition. There is no cure or approved therapy for AA; however, some people find that medications approved for other purposes can help regrow hair.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

Last Updated: 14 Aug 2014

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Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

Last Updated: 20 Mar 2013

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National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

Last Updated: 8 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alopecia Areata" for support, advocacy or research.

Bald Girls Do Lunch Inc

Bald Girls Do Lunch (BGDL) helps women with alopecia areata live full and fulfilling lives, and it’s all centered around the idea of getting together for “lunch.” Our lunches and other events are fun, friendly, educational, relaxing and, most of all, totally empowering. By being with people who experience the same things as you, your self-esteem improves and you gain confidence, camaraderie and a powerful sense of community.

http://www.baldgirlsdolunch.org

Last Updated: 14 Aug 2014

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Children's Alopecia Project, Inc.

We help children living with hair loss due to all forms of Alopecia. We raise awareness and build self-esteem so the kids can become stronger teens and more productive adults and the advocates of tomorrow.

http://www.childrensalopeciaproject.org

Last Updated: 20 Mar 2013

View Details
National Alopecia Areata Foundation

The National Alopecia Areata Foundation (NAAF) supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata.

http://www.naaf.org

Last Updated: 8 Mar 2013

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General Support Organizations

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General Resources

How Are You Nurturing Your Self Image

Patient-focused education for women with alopecia diagnoses.

Updated 14 Aug 2014

Open Doc
Understanding the Lives of Women with Alopecia Areata

Public awareness and patient-focused Infographic suitable for printing

Updated 14 Aug 2014

Open Doc
Video: Bald Girls Do Lunch (NYC)

"Spring in the City": Bald Girls Do Lunch Founder Thea Chassin hosts a BGDL evening in New York City

Updated 14 Aug 2014

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VIDEO: BGDL on the TODAY SHOW

The TODAY show came on location with Thea Chassin and Bald Girls Do Lunch in Illinois

Updated 14 Aug 2014

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National Public Radio on location with BGDL

NPR producer Patrick Skahill interviews Thea Chassin on location at Bald Girls Do Lunch in Connecticut.

Updated 14 Aug 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alopecia Areata" returned 246 free, full-text research articles on human participants. First 3 results:

STABILITY OF SOLUTIONS OF 2,3-DIPHENYLCYCLOPROPENONE IN VARIOUS SOLVENTS. A NOVEL FORMULA - DIPHENYLCYCLOPROPENONE IN ISOPROPANOL MAY BE USEFUL IN TOPICAL THERAPY OF PATIENTS WITH ALOPECIA AREATA.
 

Author(s): Katarzyna Borowska, Tomasz Wasylyszyn

Journal: Acta Pol Pharm. 2017 Mar;74(2):459-464.

 

The aim of this study was to evaluate the chemical stability of diphenylcyclopropenone (DCP) in var- ious solvents. DCP is being used in topical therapy in patients with alopecia areata (AA). The solvents for DCP used so far were acetone, ethanol and propylene glycol. DCP is supposed ...

Last Updated: 31 Dec 1969

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SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction.
 

Author(s): Zhen Gao, Yu-Qing Jin, Wei Wu

Journal: Oncotarget. 2017 May;8(20):33432-33443.

 

Alopecia areata is one of the most common autoimmune diseases resulting from T cell-mediated damage of hair follicles. CD8+ T cells infiltrate hair follicles and are responsible for destruction of hair follicles. However the underlying mechanisms for hair loss remain still obscure. ...

Last Updated: 31 Dec 1969

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Parent-of-origin Effect in Alopecia Areata: A Large-scale Pedigree Study.
 

Author(s): Silke Redler, F Buket Ü Basmanav, Bettina Blaumeiser, Natalie Garcia Bartels, Gerhard Lutz, Aylar Tafazzoli, Roland Kruse, Hans Wolff, Markus Böhm, Ulrike Blume-Peytavi, Tim Becker, Markus M Nöthen, Regina C Betz

Journal: Acta Derm. Venereol.. 2017 Jul;97(7):862-863.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alopecia Areata" returned 46 free, full-text review articles on human participants. First 3 results:

The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm.
 

Author(s): Yael Renert-Yuval, Emma Guttman-Yassky

Journal: Adv Ther. 2017 Jul;34(7):1594-1609.

 

Alopecia areata (AA), a prevalent inflammatory cause of hair loss, lacks FDA-approved therapeutics for extensive cases, which are associated with very poor rates of spontaneous hair regrowth and major psychological distress. Current treatments for severe cases include broad immune-suppressants, ...

Last Updated: 31 Dec 1969

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The Changing Landscape of Alopecia Areata: The Translational Landscape.
 

Author(s): Etienne C E Wang, Angela M Christiano

Journal: Adv Ther. 2017 Jul;34(7):1586-1593.

 

Recent genetic and preclinical studies have increased our understanding of the immunopathogenesis of alopecia areata (AA). This has allowed expedited development of targeted therapies for the treatment of AA, and a paradigm shift in our approach and understanding of autoimmunity and ...

Last Updated: 31 Dec 1969

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The Changing Landscape of Alopecia Areata: An Introduction.
 

Author(s): George Han

Journal: Adv Ther. 2017 Jul;34(7):1584-1585.

 

Alopecia areata is an extremely common autoimmune condition affecting hair. Severe forms of alopecia areata exist, with existing treatments consisting of systemic immunosuppressants with numerous side effects. Recently, breakthroughs have been made in both understanding the pathogenesis ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia Areata
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 11 Apr 2017

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Intralesional Steroids in the Treatment of Alopecia Areata
 

Status: Recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 28 Jul 2017

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Cryotherapy Versus Steroids In Alopecia Areata:Trichoscopic Evaluation
 

Status: Not yet recruiting

Condition Summary: Alopecia Areata

 

Last Updated: 21 Mar 2018

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