Glucocorticoid Resistance

Common Name(s)

Glucocorticoid Resistance

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glucocorticoid Resistance" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glucocorticoid Resistance" returned 88 free, full-text research articles on human participants. First 3 results:

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells.
 

Author(s): Ajay Palagani, Ken Op de Beeck, Stefan Naulaerts, Jolien Diddens, Chandra Sekhar Chirumamilla, Guy Van Camp, Kris Laukens, Karen Heyninck, Sarah Gerlo, Pieter Mestdagh, Joke Vandesompele, Wim Vanden Berghe

Journal:

 

Glucocorticoids (GCs) selectively trigger cell death in the multiple myeloma cell line MM1S which express NR3C1/Glucocorticoid Receptor (GR) protein, but fail to kill MM1R cells which lack GR protein. Given recent demonstrations of altered microRNA profiles in a diverse range of haematological ...

Last Updated: 5 Dec 2014

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Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance.
 

Author(s): Seong-Su Han, Sangwoo Han, Natalie L Kamberos

Journal: Biochem. Biophys. Res. Commun.. 2014 Sep;452(3):669-75.

 

Piperlongumine (PL), a pepper plant alkaloid from Piper longum, has anti-inflammatory and anti-cancer properties. PL selectively kills both solid and hematologic cancer cells, but not normal counterparts. Here we evaluated the effect of PL on the proliferation and survival of B-cell ...

Last Updated: 29 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glucocorticoid Resistance" returned 17 free, full-text review articles on human participants. First 3 results:

Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes.
 

Author(s): Alex Rafacho, Henrik Orts├Ąter, Angel Nadal, Ivan Quesada

Journal: J. Endocrinol.. 2014 Dec;223(3):R49-62.

 

Glucocorticoids (GCs) are broadly prescribed for numerous pathological conditions because of their anti-inflammatory, antiallergic and immunosuppressive effects, among other actions. Nevertheless, GCs can produce undesired diabetogenic side effects through interactions with the regulation ...

Last Updated: 25 Oct 2014

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Primary generalized familial and sporadic glucocorticoid resistance (Chrousos syndrome) and hypersensitivity.
 

Author(s): Evangelia Charmandari, Tomoshige Kino, George P Chrousos

Journal: Endocr Dev. 2013 ;24():67-85.

 

Familial or sporadic primary generalized glucocorticoid resistance or Chrousos syndrome is a rare genetic condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids and a consequent hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis. ...

Last Updated: 8 Feb 2013

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Primary generalized glucocorticoid resistance and hypersensitivity.
 

Author(s): Evangelia Charmandari

Journal: Horm Res Paediatr. 2011 ;76(3):145-55.

 

The human glucocorticoid receptor (hGR) is a ubiquitously expressed intracellular, ligand-dependent transcription factor, which mediates the action of glucocorticoids and influences physiological functions essential for life. Alterations in the molecular mechanisms of hGR action impair ...

Last Updated: 14 Oct 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Steroid Treatment for Hypereosinophilic Syndrome
 

Status: Recruiting

Condition Summary: Hypereosinophilia

 

Last Updated: 16 Jun 2015

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