Glomerulonephritis

Common Name(s)

Glomerulonephritis

Glomerulonephritis is a type of kidney disease in which there is inflammation of the glomeruli, the tiny filters that remove excess waste and fluids from the blood.  It may be acute or chronic (coming on gradually), and may occur on its own (primary) or be caused by another condition (secondary). Signs and symptoms may depend on the type and cause of the condition and may include blood in the urine; foamy urine; swelling of the face, eyes, or other body parts; abdominal pain; high blood pressure; fatigue; and/or other symptoms. If the condition is severe or prolonged, the kidneys can become damaged.  It may be caused by a variety of infections and diseases, and sometimes the cause is unknown. Treatment depends on the cause, type and severity of the condition.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glomerulonephritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glomerulonephritis" returned 1215 free, full-text research articles on human participants. First 3 results:

Glomerulonephritis and granulomatous vasculitis in kidney as a complication of the use of BRAF and MEK inhibitors in the treatment of metastatic melanoma: A case report.
 

Author(s): Mehdi Maanaoui, Camille Saint-Jacques, Viviane Gnemmi, Marie Frimat, Arnaud Lionet, Marc Hazzan, Christian Noël, François Provot

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7196.

 

BRAF and MEK inhibitors have significantly improved the prognosis of metastatic melanoma, by inhibiting both the mitogen-activated protein kinase (MAP-kinase) pathway. They are associated with infrequent adverse kidney events. Most of these are related to the use of BRAF inhibitors ...

Last Updated: 22 Jun 2017

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Different types of glomerulonephritis associated with the dysregulation of the complement alternative pathway in 2 brothers: A case report.
 

Author(s): Pei Chen, Li Zhu, Feng Yu, Sha-Sha Han, Si-Jun Meng, Wei-Yi Guo, Hong Zhang, Yan Song

Journal: Medicine (Baltimore). 2017 Jun;96(24):e7144.

 

C3 glomerulonephritis (C3GN) and complement-mediated hemolytic uremic syndrome (HUS) both result from the abnormal regulation of the complement system. A significant number of patients with C3GN or complement-mediated HUS have mutations of more than 1 complement protein. This discovery ...

Last Updated: 14 Jun 2017

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Unusual Proliferative Glomerulonephritis in a Patient Diagnosed to Have Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome with a Novel Mutation in the GATA3 Gene.
 

Author(s): Michitsugu Kamezaki, Tetsuro Kusaba, Takaomi Adachi, Noriyuki Yamashita, Mayumi Nakata, Noriyoshi Ota, Yayoi Shiotsu, Mami Ishida, Takeshi Usui, Keiichi Tamagaki

Journal: Intern. Med.. 2017 ;56(11):1393-1397.

 

Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disease caused by GATA3 mutations. Although several cases with variable renal features have been reported, the presence of histological changes within the glomeruli in adult ...

Last Updated: 1 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glomerulonephritis" returned 137 free, full-text review articles on human participants. First 3 results:

Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond.
 

Author(s): Terry King-Wing Ma, Stephen P McAdoo, Frederick Wai Keung Tam

Journal: Nephrol. Dial. Transplant.. 2017 01;32(suppl_1):i129-i138.

 

Glomerulonephritis (GN) affects patients of all ages and is an important cause of morbidity and mortality. Non-selective immunosuppressive drugs have been used in immune-mediated GN but often result in systemic side effects and occasionally fatal infective complications. There is ...

Last Updated: 9 Apr 2017

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CD4(+) T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes.
 

Author(s): Christan F Krebs, Oliver M Steinmetz

Journal: Mediators Inflamm.. 2016 ;2016():5393894.

 

Multiple studies have identified CD4(+) T cells as central players of glomerulonephritis (GN). Cells of the Th1 and Th17 responses cause renal tissue damage, while Tregs mediate protection. Recently, a high degree of plasticity among these T cell lineages was proposed. During inflammation, ...

Last Updated: 15 Dec 2016

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C3 glomerulonephritis in multiple myeloma: A case report and literature review.
 

Author(s): Guang Yin, Zhen Cheng, Cai-Hong Zeng, Zhi-Hong Liu

Journal: Medicine (Baltimore). 2016 Sep;95(37):e4843.

 

C3 glomerulonephritis (C3 GN) is a recently defined entity characterized by predominant C3 deposition in glomeruli due to abnormal activation of the alternative pathway of complement system. C3 GN has been reported to be associated with several systemic diseases. However, the association ...

Last Updated: 16 Sep 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

ACE-inhibitors in Extracapillary Glomerulonephritis
 

Status: Recruiting

Condition Summary: Extracapillary Glomerulonephritis

 

Last Updated: 19 Jul 2017

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Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis
 

Status: Not yet recruiting

Condition Summary: Membranoproliferative Glomerulonephritis

 

Last Updated: 15 Jun 2017

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Acute Post Streptococcal Glomerulonephritis
 

Status: Not yet recruiting

Condition Summary: PSGN - Post-Streptococcal Glomerulonephritis

 

Last Updated: 13 Jun 2017

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