Angioedema

Common Name(s)

Angioedema

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Angioedema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Angioedema" returned 441 free, full-text research articles on human participants. First 3 results:

Episodic angioedema associated with eosinophilia.
 

Author(s): Fang Liu, Wenxing Hu, Haibo Liu, Min Zhang, Hong Sang

Journal: An Bras Dermatol. ;92(4):534-536.

 

We report a 12-year-old girl who presented with recurrent angioedema on the face, trunk, and extremities, and concomitant marked weight gain for 5 years. During the episode, her white blood cell count increased to 47.7×109/L with 89.9% eosinophils, followed by elevated serum level ...

Last Updated: 27 Sep 2017

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Preventing Hereditary Angioedema Attacks in Children Using Cinryze®: Interim Efficacy and Safety Phase 3 Findings.
 

Author(s): Emel Aygören-Pürsün, Daniel Soteres, Dumitru Moldovan, Jim Christensen, Arthur Van Leerberghe, James Hao, Jennifer Schranz, Kraig W Jacobson, Inmaculada Martinez-Saguer

Journal: Int. Arch. Allergy Immunol.. 2017 ;173(2):114-119.

 

Hereditary angioedema (HAE) is a rare genetic disease causing unpredictable and potentially life-threatening subcutaneous and submucosal edematous attacks. Cinryze® (Shire ViroPharma Inc., Lexington, MA, USA), a nanofiltered C1 inhibitor (C1-INH), is approved in Europe for the treatment, ...

Last Updated: 29 Jun 2017

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Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.
 

Author(s): Hilary Longhurst, Marco Cicardi, Timothy Craig, Konrad Bork, Clive Grattan, James Baker, Huamin H Li, Avner Reshef, James Bonner, Jonathan A Bernstein, John Anderson, William R Lumry, Henriette Farkas, Constance H Katelaris, Gordon L Sussman, Joshua Jacobs, Marc Riedl, Michael E Manning, Jacques Hebert, Paul K Keith, Shmuel Kivity, Sergio Neri, Donald S Levy, Maria L Baeza, Robert Nathan, Lawrence B Schwartz, Teresa Caballero, William Yang, Ioana Crisan, María D Hernandez, Iftikhar Hussain, Michael Tarzi, Bruce Ritchie, Pavlina Králíčková, Mar Guilarte, Syed M Rehman, Aleena Banerji, Richard G Gower, Debra Bensen-Kennedy, Jonathan Edelman, Henrike Feuersenger, John-Philip Lawo, Thomas Machnig, Dipti Pawaskar, Ingo Pragst, Bruce L Zuraw,

Journal: N. Engl. J. Med.. 2017 03;376(12):1131-1140.

 

Hereditary angioedema is a disabling, potentially fatal condition caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein. In a phase 2 trial, the use of CSL830, a nanofiltered C1 inhibitor preparation that is suitable for subcutaneous injection, resulted ...

Last Updated: 22 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Angioedema" returned 46 free, full-text review articles on human participants. First 3 results:

Current and future therapies for the treatment of histamine-induced angioedema.
 

Author(s): Christine James, Jonathan A Bernstein

Journal: Expert Opin Pharmacother. 2017 Feb;18(3):253-262.

 

Angioedema, a sudden, self-limited swelling of localized areas of any part of the body that may or may not be associated with urticaria, is thought to be the result of a mast-cell mediated process versus a bradykinin etiology. Understanding the mechanism is key in determining the ...

Last Updated: 13 Jan 2017

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Novelties in the Diagnosis and Treatment of Angioedema.
 

Author(s): M Cicardi, C Suffritti, F Perego, S Caccia

Journal: J Investig Allergol Clin Immunol. 2016 ;26(4):212-21; quiz two pages after page 221.

 

Angioedema is defined as local, noninflammatory, self-limiting edema that is circumscribed owing to increased leakage of plasma from the capillaries located in the deep layers of the skin and the mucosae. Two mediators, histamine and bradykinin, account for most cases of angioedema. ...

Last Updated: 29 Jul 2016

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Bradykinin-mediated angioedema.
 

Author(s): Krystyna Obtułowicz

Journal: Pol. Arch. Med. Wewn.. 2016 ;126(1-2):76-85.

 

Angioedema and urticaria often constitute a challenge in daily clinical practice. They may either co- -occur or present as independent conditions. They are characterized by a complex pathomechanism, and their symptoms may be triggered by diverse factors. These differences are crucial ...

Last Updated: 4 Feb 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Idiopathic Angioedema With Xolair as Add-on Therapy
 

Status: Recruiting

Condition Summary: Idiopathic Angioedema

 

Last Updated: 13 Oct 2017

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Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients
 

Status: Recruiting

Condition Summary: Hereditary Angioedema

 

Last Updated: 14 Oct 2016

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Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema
 

Status: Recruiting

Condition Summary: Hereditary Angioedema (HAE)

 

Last Updated: 11 Oct 2017

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