Glioma

Common Name(s)

Glioma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioma" for support, advocacy or research.

National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioma" for support, advocacy or research.

National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glioma" returned 3272 free, full-text research articles on human participants. First 3 results:

DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells.
 

Author(s): Daoyang Zhou, Yingfeng Wan, Dajiang Xie, Yirong Wang, Junhua Wei, Qingfeng Yan, Peng Lu, Lianjie Mo, Jixi Xie, Shuxu Yang, Xuchen Qi

Journal:

 

Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on glioblastoma chemoresistance has not been well defined. ...

Last Updated: 4 Sep 2015

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Does Tenascin have Clinical Implications in Pathological Grade of Glioma Patients?: A Systematic Meta-Analysis.
 

Author(s): Xiangyi Kong, Wenbin Ma, Yongning Li, Yu Wang, Jian Guan, Jun Gao, Junji Wei, Yong Yao, Wei Lian, Zhiqin Xu, Wanchen Dou, Bing Xing, Zuyuan Ren, Changbao Su, Yi Yang, Renzhi Wang

Journal: Medicine (Baltimore). 2015 Aug;94(32):e1330.

 

Tenascin (TN) is an extracellular oligomeric glycoprotein that participates in the adhesion of cells to extracellular matrixc (ECM). Studies have shown that the expression levels of TN are upregulated in a variety of cancers, including colon cancer, lung cancer, brain tumor, and breast ...

Last Updated: 13 Aug 2015

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MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression.
 

Author(s): Qian Ma, Yan Zhang, Ran Meng, Kun Ming Xie, Ying Xiong, Song Lin, Zong Lin K He, Tao Tao, Ying Yang, Ji Zong Zhao, Jun Qi He

Journal: Biomed. Environ. Sci.. 2015 Jul;28(7):502-9.

 

To investigate the role and molecular mechanism of membrane-associated guanylate kinase inverted 3 (MAGI3) in glioma cell proliferation.

Last Updated: 7 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glioma" returned 206 free, full-text review articles on human participants. First 3 results:

Drug delivery strategies to enhance the permeability of the blood-brain barrier for treatment of glioma.
 

Author(s): Fang Zhang, Chun-Lei Xu, Chun-Mei Liu

Journal:

 

Gliomas are amongst the most insidious and destructive types of brain cancer and are associated with a poor prognosis, frequent recurrences, and extremely high lethality despite combination treatment of surgery, radiotherapy, and chemotherapy. The existence of the blood-brain barrier ...

Last Updated: 30 Apr 2015

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Systematic review on the association between ERCC1 rs3212986 and ERCC2 rs13181 polymorphisms and glioma risk.
 

Author(s): C X Zhou, J H Zhao

Journal:

 

Several studies have examined the association between excision repair cross-complementation group 1 (ERCC1) C8092A and ERCC2 Lys751Gln polymorphisms and glioma risk, but the results have been inconclusive. We conducted a meta-analysis of 12 studies to determine the association between ...

Last Updated: 14 Apr 2015

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Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion.
 

Author(s): Lucie Dardevet, Dipti Rani, Tarek Abd El Aziz, Ingrid Bazin, Jean-Marc Sabatier, Mahmoud Fadl, Elisabeth Brambilla, Michel De Waard

Journal:

 

Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. Initially, chlorotoxin was used as a pharmacological tool to characterize chloride channels. While studying glioma-specific chloride currents, it was soon discovered that ...

Last Updated: 1 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
 

Status: Recruiting

Condition Summary: Pilomyxoid Astrocytoma; Pilocytic Astrocytoma; Glioma, Astrocytic; Optic Nerve Glioma; Pleomorphic Xanthoastrocytoma; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliosarcoma; Diffuse Intrinsic Pontine Glioma; DIPG; Low-grade Glioma; Brainstem Glioma

 

Last Updated: 14 Oct 2015

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Proton Radiation Therapy for Gliomas
 

Status: Recruiting

Condition Summary: Low Grade Glioma; WHO Grade 3 Glioma With IDH1 Mutation; WHO Grade 3 Glioma With 1p/19q Codeletion

 

Last Updated: 13 Jan 2016

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A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
 

Status: Recruiting

Condition Summary: Newly Diagnosed Pediatric Pontine Glioma.; Newly Diagnosed Pediatric High Grade Glioma.; Recurrent Pediatric High Grade Glioma.; Recurrent Pediatric Low Grade Glioma.

 

Last Updated: 22 Jan 2016

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