Glioma

Common Name(s)

Glioma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioma" for support, advocacy or research.

National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioma" for support, advocacy or research.

National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glioma" returned 2849 free, full-text research articles on human participants. First 3 results:

Late neurological sequelae due to brainstem irradiation for an assumed glioma.
 

Author(s): Florian Roser, Marcos S Tatagiba, Florian H Ebner

Journal: Acta Neurol Taiwan. 2014 Jun;23(2):55-8.

 

There is ongoing discussion whether radiotherapy might be beneficial in the treatment of intracranial cavernomas, however long-term sequelae due to brainstem irradiation may exist.

Last Updated: 3 Jun 2015

Go To URL
Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
 

Author(s): Eva Bernhart, Sabine Damm, Andrea Wintersperger, Christoph Nusshold, Anna Martina Brunner, Ioanna Plastira, Gerald Rechberger, Helga Reicher, Christian Wadsack, Andreas Zimmer, Ernst Malle, Wolfgang Sattler

Journal: Biochem. Pharmacol.. 2015 Jul;96(2):119-30.

 

Glioblastoma is the most common malignant brain tumor, which, despite combined radio- and chemotherapy, recurs and is invariably fatal for affected patients. Members of the sphingolipid (SL) family are potent effectors of glioma cell proliferation. In particular sphingosine-1-phosphate ...

Last Updated: 15 Jun 2015

Go To URL
The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines.
 

Author(s): Rashid Elhag, Elizabeth A Mazzio, Karam F A Soliman

Journal: Anticancer Res.. 2015 Mar;35(3):1263-9.

 

Glioblastoma multiforme (GBM) is an intractable brain tumor, associated with poor prognosis and low survival rate. Combination therapy such as surgery, radiotherapy and temozolomide is considered standard in overcoming this aggressive cancer, despite poor prognosis. There is a need ...

Last Updated: 9 Mar 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glioma" returned 183 free, full-text review articles on human participants. First 3 results:

Recent advances in the role of toll-like receptors and TLR agonists in immunotherapy for human glioma.
 

Author(s): Shuanglin Deng, Shan Zhu, Yuan Qiao, Yong-Jun Liu, Wei Chen, Gang Zhao, Jingtao Chen

Journal: Protein Cell. 2014 Dec;5(12):899-911.

 

Gliomas are extremely aggressive brain tumors with a very poor prognosis. One of the more promising strategies for the treatment of human gliomas is targeted immunotherapy where antigens that are unique to the tumors are exploited to generate vaccines. The approach, however, is complicated ...

Last Updated: 9 Dec 2014

Go To URL
Antibody-based immunotherapy for malignant glioma.
 

Author(s): Patrick C Gedeon, Katherine A Riccione, Peter E Fecci, John H Sampson

Journal: Semin. Oncol.. 2014 Aug;41(4):496-510.

 

Conventional therapy for malignant glioma (MG) fails to specifically eliminate tumor cells, resulting in toxicity that limits therapeutic efficacy. In contrast, antibody-based immunotherapy uses the immune system to eliminate tumor cells with exquisite specificity. Increased understanding ...

Last Updated: 1 Sep 2014

Go To URL
Standard of care and future pharmacological treatment options for malignant glioma: an urgent need for screening and identification of novel tumor-specific antigens.
 

Author(s): Kristen A Batich, John H Sampson

Journal: Expert Opin Pharmacother. 2014 Oct;15(14):2047-61.

 

Malignant gliomas (MGs) represent the most common primary brain tumors in adults, the most deadly of which is grade IV glioblastoma. Patients with glioblastoma undergoing current standard-of-care therapy have a median survival of 12 - 15 months.

Last Updated: 10 Sep 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
 

Status: Recruiting

Condition Summary: Pilomyxoid Astrocytoma; Pilocytic Astrocytoma; Glioma, Astrocytic; Optic Nerve Glioma; Pleomorphic Xanthoastrocytoma; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliosarcoma; Diffuse Intrinsic Pontine Glioma; DIPG; Low-grade Glioma

 

Last Updated: 22 Apr 2015

Go to URL
18F-DOPA-PET in Planning Surgery in Patients With Gliomas
 

Status: Recruiting

Condition Summary: Acoustic Schwannoma; Adult Anaplastic (Malignant) Meningioma; Adult Anaplastic Astrocytoma; Adult Anaplastic Ependymoma; Adult Anaplastic Oligodendroglioma; Adult Brain Stem Glioma; Adult Choroid Plexus Neoplasm; Adult Craniopharyngioma; Adult Diffuse Astrocytoma; Adult Ependymoblastoma; Adult Ependymoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Medulloblastoma; Adult Mixed Glioma; Adult Myxopapillary Ependymoma; Adult Oligodendroglioma; Adult Papillary Meningioma; Adult Pilocytic Astrocytoma; Adult Pineal Gland Astrocytoma; Adult Pineoblastoma; Adult Pineocytoma; Adult Primary Melanocytic Lesion of Meninges; Adult Subependymal Giant Cell Astrocytoma; Adult Subependymoma; Childhood Cerebellar Anaplastic Astrocytoma; Childhood Cerebellar Astrocytoma; Childhood Cerebral Anaplastic Astrocytoma; Childhood Cerebral Astrocytoma; Childhood Choroid Plexus Neoplasm; Childhood Craniopharyngioma; Childhood Ependymoblastoma; Childhood Grade I Meningioma; Childhood Grade II Meningioma; Childhood Grade III Meningioma; Childhood Infratentorial Ependymoma; Childhood Mixed Glioma; Childhood Supratentorial Ependymoma; Malignant Adult Intracranial Hemangiopericytoma; Medulloepithelioma; Newly Diagnosed Childhood Ependymoma; Recurrent Adult Brain Neoplasm; Recurrent Childhood Anaplastic Astrocytoma; Recurrent Childhood Anaplastic Oligoastrocytoma; Recurrent Childhood Anaplastic Oligodendroglioma; Recurrent Childhood Brain Stem Glioma; Recurrent Childhood Cerebellar Astrocytoma; Recurrent Childhood Cerebral Astrocytoma; Recurrent Childhood Diffuse Astrocytoma; Recurrent Childhood Ependymoma; Recurrent Childhood Fibrillary Astrocytoma; Recurrent Childhood Gemistocytic Astrocytoma; Recurrent Childhood Giant Cell Glioblastoma; Recurrent Childhood Glioblastoma; Recurrent Childhood Gliomatosis Cerebri; Recurrent Childhood Gliosarcoma; Recurrent Childhood Medulloblastoma; Recurrent Childhood Oligoastrocytoma; Recurrent Childhood Oligodendroglioma; Recurrent Childhood Pilocytic Astrocytoma; Recurrent Childhood Pilomyxoid Astrocytoma; Recurrent Childhood Pineoblastoma; Recurrent Childhood Pleomorphic Xanthoastrocytoma; Recurrent Childhood Protoplasmic Astrocytoma; Recurrent Childhood Subependymal Giant Cell Astrocytoma; Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor; Recurrent Childhood Visual Pathway Glioma; Untreated Childhood Anaplastic Astrocytoma; Untreated Childhood Anaplastic Oligoastrocytoma; Untreated Childhood Anaplastic Oligodendroglioma; Untreated Childhood Brain Stem Glioma; Untreated Childhood Diffuse Astrocytoma; Untreated Childhood Fibrillary Astrocytoma; Untreated Childhood Gemistocytic Astrocytoma; Untreated Childhood Giant Cell Glioblastoma; Untreated Childhood Glioblastoma; Untreated Childhood Gliomatosis Cerebri; Untreated Childhood Gliosarcoma; Untreated Childhood Medulloblastoma; Untreated Childhood Oligoastrocytoma; Untreated Childhood Oligodendroglioma; Untreated Childhood Pilocytic Astrocytoma; Untreated Childhood Pilomyxoid Astrocytoma; Untreated Childhood Pineoblastoma; Untreated Childhood Pleomorphic Xanthoastrocytoma; Untreated Childhood Protoplasmic Astrocytoma; Untreated Childhood Subependymal Giant Cell Astrocytoma; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor; Untreated Childhood Visual Pathway Glioma

 

Last Updated: 23 Jun 2015

Go to URL
Proton Radiation Therapy for Gliomas
 

Status: Recruiting

Condition Summary: Low Grade Glioma; WHO Grade 3 Glioma With IDH1 Mutation; WHO Grade 3 Glioma With 1p/19q Codeletion

 

Last Updated: 17 Apr 2015

Go to URL