Glioblastoma

Common Name(s)

Glioblastoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glioblastoma" returned 2119 free, full-text research articles on human participants. First 3 results:

Bevacizumab for newly diagnosed glioblastoma.
 

Author(s): Mark R Gilbert, Erik P Sulman, Minesh P Mehta

Journal: N. Engl. J. Med.. 2014 May;370(21):2048-9.

 

Last Updated: 22 May 2014

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Characterization and management of dermatologic adverse events with the NovoTTF-100A System, a novel anti-mitotic electric field device for the treatment of recurrent glioblastoma.
 

Author(s): Mario E Lacouture, Mary Elizabeth Davis, Grace Elzinga, Nicholas Butowski, David Tran, John L Villano, Lucianna DiMeglio, Angela M Davies, Eric T Wong

Journal: Semin. Oncol.. 2014 Jun;41 Suppl 4():S1-14.

 

The NovoTTF-100A System (NovoTTF™ Therapy, Novocure Inc.) is a device that delivers alternating electric fields (TTFields) to tumor cells and interferes with mitosis. It is approved for use as monotherapy for the treatment of recurrent glioblastoma (rGB). TTFields are delivered ...

Last Updated: 5 May 2014

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Similarity in targets with REST points to neural and glioblastoma related miRNAs.
 

Author(s): Marie L Gebhardt, Stefanie Reuter, Ralf Mrowka, Miguel A Andrade-Navarro

Journal: Nucleic Acids Res.. 2014 ;42(9):5436-46.

 

There are groups of genes that need coordinated repression in multiple contexts, for example if they code for proteins that work together in a pathway or in a protein complex. Redundancy of biological regulatory networks implies that such coordinated repression might occur at both ...

Last Updated: 20 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glioblastoma" returned 139 free, full-text review articles on human participants. First 3 results:

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.
 

Author(s): Dominik Sturm, Sebastian Bender, David T W Jones, Peter Lichter, Jacques Grill, Oren Becher, Cynthia Hawkins, Jacek Majewski, Chris Jones, Joseph F Costello, Antonio Iavarone, Kenneth Aldape, Cameron W Brennan, Nada Jabado, Stefan M Pfister

Journal: Nat. Rev. Cancer. 2014 Feb;14(2):92-107.

 

We have extended our understanding of the molecular biology that underlies adult glioblastoma over many years. By contrast, high-grade gliomas in children and adolescents have remained a relatively under-investigated disease. The latest large-scale genomic and epigenomic profiling ...

Last Updated: 24 Jan 2014

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Antivascular endothelial growth factor antibody for treatment of glioblastoma multiforme.
 

Author(s): Joseph A Hanson, Frank P K Hsu, Arun T Jacob, Daniela A Bota, Daniela Alexandru

Journal: Perm J. 2013 ;17(4):68-74.

 

Despite aggressive investigation, glioblastoma multiforme (GBM) remains one of the deadliest cancers, with low progression-free survival and high one-year mortality. Current first-line therapy includes surgery with adjuvant radiation therapy and cytotoxic chemotherapy, but virtually ...

Last Updated: 23 Dec 2013

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The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture.
 

Author(s): Elizabeth M Haley, Yonghyun Kim

Journal: Cancer Lett.. 2014 Apr;346(1):1-5.

 

Glioblastoma multiforme (GBM) is the most malignant form of central nervous system tumor, and current therapies are largely ineffective at treating the cancer. Developing a more complete understanding of the mechanisms controlling the tumor is important in order to explore new possible ...

Last Updated: 5 Mar 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
 

Status: Recruiting

Condition Summary: Glioblastoma; Small Cell Glioblastoma; Giant Cell Glioblastoma; Gliosarcoma; Glioblastoma With Oligodendroglial Component; Recurrent Glioblastoma; Relapsed Glioblastoma

 

Last Updated: 8 Jul 2014

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Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
 

Status: Recruiting

Condition Summary: Glioblastoma; Small Cell Glioblastoma; Giant Cell Glioblastoma; Gliosarcoma; Glioblastoma With Oligodendroglial Component

 

Last Updated: 6 Aug 2014

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Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
 

Status: Recruiting

Condition Summary: Glioblastoma; Glioblastoma Multiforme; Glioma; Astrocytoma; Brain Tumor

 

Last Updated: 18 Dec 2013

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