Glioblastoma

Common Name(s)

Glioblastoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glioblastoma" returned 2154 free, full-text research articles on human participants. First 3 results:

Bevacizumab for newly diagnosed glioblastoma.
 

Author(s): Mark R Gilbert, Erik P Sulman, Minesh P Mehta

Journal: N. Engl. J. Med.. 2014 May;370(21):2048-9.

 

Last Updated: 22 May 2014

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Characterization and management of dermatologic adverse events with the NovoTTF-100A System, a novel anti-mitotic electric field device for the treatment of recurrent glioblastoma.
 

Author(s): Mario E Lacouture, Mary Elizabeth Davis, Grace Elzinga, Nicholas Butowski, David Tran, John L Villano, Lucianna DiMeglio, Angela M Davies, Eric T Wong

Journal: Semin. Oncol.. 2014 Jun;41 Suppl 4():S1-14.

 

The NovoTTF-100A System (NovoTTF™ Therapy, Novocure Inc.) is a device that delivers alternating electric fields (TTFields) to tumor cells and interferes with mitosis. It is approved for use as monotherapy for the treatment of recurrent glioblastoma (rGB). TTFields are delivered ...

Last Updated: 5 May 2014

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Similarity in targets with REST points to neural and glioblastoma related miRNAs.
 

Author(s): Marie L Gebhardt, Stefanie Reuter, Ralf Mrowka, Miguel A Andrade-Navarro

Journal: Nucleic Acids Res.. 2014 ;42(9):5436-46.

 

There are groups of genes that need coordinated repression in multiple contexts, for example if they code for proteins that work together in a pathway or in a protein complex. Redundancy of biological regulatory networks implies that such coordinated repression might occur at both ...

Last Updated: 20 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glioblastoma" returned 142 free, full-text review articles on human participants. First 3 results:

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.
 

Author(s): Dominik Sturm, Sebastian Bender, David T W Jones, Peter Lichter, Jacques Grill, Oren Becher, Cynthia Hawkins, Jacek Majewski, Chris Jones, Joseph F Costello, Antonio Iavarone, Kenneth Aldape, Cameron W Brennan, Nada Jabado, Stefan M Pfister

Journal: Nat. Rev. Cancer. 2014 Feb;14(2):92-107.

 

We have extended our understanding of the molecular biology that underlies adult glioblastoma over many years. By contrast, high-grade gliomas in children and adolescents have remained a relatively under-investigated disease. The latest large-scale genomic and epigenomic profiling ...

Last Updated: 24 Jan 2014

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Standards of care and novel approaches in the management of glioblastoma multiforme.
 

Author(s): Andreas F Hottinger, Roger Stupp, Krisztian Homicsko

Journal: Chin J Cancer. 2014 Jan;33(1):32-9.

 

Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Standard therapeutic approaches provide modest improvement in the progression-free and overall survival, necessitating the investigation of novel therapies. We review the standard treatment options ...

Last Updated: 3 Jan 2014

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Novel strategies in glioblastoma surgery aim at safe, supra-maximum resection in conjunction with local therapies.
 

Author(s): John G Wolbers

Journal: Chin J Cancer. 2014 Jan;33(1):8-15.

 

The biggest challenge in neuro-oncology is the treatment of glioblastoma, which exhibits poor prognosis and is increasing in incidence in an increasing aging population. Diverse treatment strategies aim at maximum cytoreduction and ensuring good quality of life. We discuss multimodal ...

Last Updated: 3 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
 

Status: Recruiting

Condition Summary: Glioblastoma; Small Cell Glioblastoma; Giant Cell Glioblastoma; Gliosarcoma; Glioblastoma With Oligodendroglial Component; Recurrent Glioblastoma; Relapsed Glioblastoma

 

Last Updated: 3 Sep 2014

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Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
 

Status: Recruiting

Condition Summary: Glioblastoma; Small Cell Glioblastoma; Giant Cell Glioblastoma; Gliosarcoma; Glioblastoma With Oligodendroglial Component

 

Last Updated: 6 Aug 2014

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Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
 

Status: Recruiting

Condition Summary: Glioma; Glioblastoma; Glioblastoma Multiforme

 

Last Updated: 24 Jun 2014

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