Glioblastoma

Common Name(s)

Glioblastoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glioblastoma" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glioblastoma" returned 2358 free, full-text research articles on human participants. First 3 results:

Complement activation in Glioblastoma multiforme pathophysiology: evidence from serum levels and presence of complement activation products in tumor tissue.
 

Author(s): T A M Bouwens, L A Trouw, R Veerhuis, C M F Dirven, M L M Lamfers, H Al-Khawaja

Journal: J. Neuroimmunol.. 2015 Jan;278():271-6.

 

Inflammation plays a key role in the pathophysiology of Glioblastoma Multiforme (GBM). Here we focus on the contribution of the so far largely ignored complement system. ELISA and immunohistochemistry were combined to assess levels and localization of critical components of the initiation- ...

Last Updated: 17 Jan 2015

Go To URL
Classification of microvascular patterns via cluster analysis reveals their prognostic significance in glioblastoma.
 

Author(s): Long Chen, Zhi-Xiong Lin, Guo-Shi Lin, Chang-Fu Zhou, Yu-Peng Chen, Xing-Fu Wang, Zong-Qing Zheng

Journal: Hum. Pathol.. 2015 Jan;46(1):120-8.

 

There are limited researches focusing on microvascular patterns (MVPs) in human glioblastoma and their prognostic impact. We evaluated MVPs of 78 glioblastomas by CD34/periodic acid-Schiff dual staining and by cluster analysis of the percentage of microvascular area for distinct microvascular ...

Last Updated: 16 Dec 2014

Go To URL
[New software for objective evaluation of brain glioblastoma resection degree].
 

Author(s): A L Krivoshapkin, G S Sergeev, A S Gaytan, V P Kurbatov, L E Kalneus, E G Tarantsev

Journal: Zh Vopr Neirokhir Im N N Burdenko. 2014 ;78(5):33-9; discussion 40.

 

The visual evaluation of the degree of GBM resection based upon postoperative enhanced MRI is still difficult. It is explained by intricate complex of tumor residual fragments, blood cells, hemostatic tissues and perifocal edema that located in the postoperative area. We introduce ...

Last Updated: 21 Nov 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glioblastoma" returned 153 free, full-text review articles on human participants. First 3 results:

Eph receptors as therapeutic targets in glioblastoma.
 

Author(s): B W Day, B W Stringer, A W Boyd

Journal: Br. J. Cancer. 2014 Sep;111(7):1255-61.

 

The dismal outlook for patients with the most aggressive and common form of adult brain cancer, glioblastoma (GBM), motivates a search for new therapeutic strategies and targets for this aggressive disease. Here we review the findings to date on the role of Eph family receptor tyrosine ...

Last Updated: 24 Sep 2014

Go To URL
Use of high-resolution volumetric MR spectroscopic imaging in assessing treatment response of glioblastoma to an HDAC inhibitor.
 

Author(s): Hyunsuk Shim, Li Wei, Chad A Holder, Ying Guo, Xiaoping P Hu, Andrew H Miller, Jeffrey J Olson

Journal: AJR Am J Roentgenol. 2014 Aug;203(2):W158-65.

 

Improved predictive imaging would enable personalization and adjustment of treatment, which are critical for patients with glioblastomain whom therapy is likely to fail. This article describes the use of MR spectroscopic imaging (MRSI) to predict early clinical and behavioral response ...

Last Updated: 24 Jul 2014

Go To URL
Nanoparticles for hyperthermic therapy: synthesis strategies and applications in glioblastoma.
 

Author(s): Jyoti Verma, Sumit Lal, Cornelis J F Van Noorden

Journal:

 

Glioblastoma multiforme (GBM) is the most common and most aggressive malignant primary brain tumor in humans. Current GBM treatment includes surgery, radiation therapy, and chemotherapy, sometimes supplemented with novel therapies. Despite recent advances, survival of GBM patients ...

Last Updated: 24 Jun 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
 

Status: Recruiting

Condition Summary: Glioma; Glioblastoma; Glioblastoma Multiforme

 

Last Updated: 22 Sep 2014

Go to URL
Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme
 

Status: Not yet recruiting

Condition Summary: Glioblastoma Multiforme; Glioblastoma - Category

 

Last Updated: 18 Apr 2014

Go to URL
Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma
 

Status: Recruiting

Condition Summary: Giant Cell Glioblastoma; Glioblastoma; Gliosarcoma

 

Last Updated: 3 Dec 2014

Go to URL