Glaucoma

Common Name(s)

Glaucoma

Glaucoma is a group of diseases in which there is a blockage of fluid drainage from the eye. When fluid cannot drain properly from the eye, the pressure inside the eye may rise to a level that can damage the optic nerve that brings information from the back of the eye (retina) resulting in vision loss and blindness. This group of diseases makes up the second most common cause of blindness.

There are multiple types of glaucoma, the most common of which is open-angle glaucoma. In open-angle glaucoma, fluid builds up in the anterior chamber of the eye because it cannot drain through a meshwork structure between the colored part of the eye that controls light entry (iris) and the lens (cornea). In this form of glaucoma, side or peripheral vision is usually lost first. Other types of glaucoma include low-tension or normal-tension glaucoma, angle-closure glaucoma, congenital glaucoma, secondary glaucoma, neovascular glaucoma, pigmentary glaucoma, and pseudoexfoliation glaucoma. In angle-closure glaucoma, the iris blocks the channel that normally allows fluid leave the front of the eye. Symptoms of angle-closure glaucoma include eye pain, nausea, blurred vision, and redness of the eye. Medical attention should be sought promptly if angle-closure glaucoma is suspected.

Glaucoma can be diagnosed with a comprehensive dilated eye exam and by measuring intraocular pressure (IOP). Regular eye exams are important because some forms of glaucoma are often asymptomatic prior to permanent vision loss. Treatment options include medication, laser surgery to create holes in the meshwork and allow fluid to drain from the anterior chamber (laser trabeculoplasty), and surgery to alter the iris to allow fluid drainage. If you have been diagnosed with glaucoma, talk to your doctor about the most current treatment options. Support groups are good sources of more information and can connect you with other people living with glaucoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

Last Updated: 14 May 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

http://www.glaucoma.org

Last Updated: 14 May 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

http://www.glaucomafoundation.org

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

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General Resources

Glaucoma Care and Treatment Information

Glaucoma Care and Treatment options

Updated 14 May 2015

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Free Glaucoma Newsletter

Information for glaucoma patients

Updated 14 May 2015

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Glaucoma Research Progress Reports

Information about glaucoma research progress

Updated 14 May 2015

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Low Vision Resources

Links to products and services available for people with low vision.

Updated 14 May 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glaucoma" returned 3495 free, full-text research articles on human participants. First 3 results:

Glaucoma, "the silent thief of sight": patients' perspectives and health seeking behaviour in Bauchi, northern Nigeria.
 

Author(s): Mohammed Mahdi Abdull, Clare Chandler, Clare Gilbert

Journal:

 

In Nigeria, glaucoma has a high prevalence and is the second cause of blindness among adults after cataract. People with glaucoma frequently present very late with advanced disease, and acceptance of and adherence to treatment is low. The purpose of the study was to explore how patients' ...

Last Updated: 22 Apr 2016

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A novel de novo Myocilin variant in a patient with sporadic juvenile open angle glaucoma.
 

Author(s): Emmanuelle Souzeau, Kathryn P Burdon, Bronwyn Ridge, Andrew Dubowsky, Jonathan B Ruddle, Jamie E Craig

Journal:

 

Glaucoma is a leading cause of irreversible blindness. Pathogenic variants in the Myocilin gene (MYOC) cause juvenile open angle glaucoma (JOAG) in 8-36% of cases, and display an autosomal dominant inheritance with high penetrance. Molecular diagnosis is important for early identification ...

Last Updated: 15 Apr 2016

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Ocular perfusion pressure and ophthalmic artery flow in patients with normal tension glaucoma.
 

Author(s): Amir Samsudin, Nadine Isaacs, Mei-Ling Sharon Tai, Norlina Ramli, Zahari Mimiwati, May May Choo

Journal:

 

Vascular insufficiency has been reported to be a cause of normal tension glaucoma (NTG). The aim of this study was to compare ocular perfusion pressure (OPP) and ophthalmic artery flow (OAF) between patients with NTG and those without glaucoma.

Last Updated: 15 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glaucoma" returned 324 free, full-text review articles on human participants. First 3 results:

Neovascular glaucoma: a retrospective review from a tertiary center in China.
 

Author(s): Na Liao, Chaohong Li, Huilv Jiang, Aiwu Fang, Shengjie Zhou, Qinmei Wang

Journal:

 

The purpose of this study is to report the prevalence, etiology, treatment and outcomes of neovascular glaucoma (NVG) in a tertiary care ophthalmic center in China.

Last Updated: 28 Jan 2016

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Actinobacillus actinomycetemcomitans Keratitis After Glaucoma Infiltration Surgery: A Clinical Report and Literature Review.
 

Author(s): Jiaxu Hong, Jianjiang Xu, Wenjun Cao, Jian Ji, Xinghuai Sun

Journal: Medicine (Baltimore). 2016 Jan;95(3):e2608.

 

Actinobacillus actinomycetemcomitans infection is a rare and easily misdiagnosed ocular disease. In this article, the authors report a chronic, purulent, and difficult-to-treat case of A actinomycetemcomitans keratitis following a glaucoma infiltration surgery.A 56-year-old man with ...

Last Updated: 28 Jan 2016

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Rho kinase inhibitors for glaucoma treatment - Review.
 

Author(s): Renato Antunes Schiave Germano, Simone Finzi, Pratap Challa, Remo Susanna Junior

Journal: Arq Bras Oftalmol. ;78(6):388-91.

 

Glaucoma is a progressive optic neuropathy characterized by the loss of ganglion cells and their axons. A major risk factor for glaucomatous visual field loss is elevated intraocular pressure (IOP), and several studies have shown that lowering IOP reduces the risk of glaucomatous ...

Last Updated: 17 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Protective Effect of Phenytoin on Glaucoma
 

Status: Not yet recruiting

Condition Summary: Primary Open Angle Glaucoma; Secondary Open Angle Glaucoma; Narrow-Angle Glaucomas; Normal Tension Glaucoma

 

Last Updated: 20 Aug 2008

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Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
 

Status: Recruiting

Condition Summary: Glaucoma, Open-Angle; Glaucoma, Primary Open Angle; Exfoliation Glaucoma; Glaucoma, Pigmentary

 

Last Updated: 13 Feb 2016

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Compare the Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Having Cataract Surgery (Hydrus III)
 

Status: Recruiting

Condition Summary: Primary Open Angle Glaucoma; Pseudoexfoliative Glaucoma; Pigmentary Dispersion Glaucoma

 

Last Updated: 27 Dec 2013

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