Glaucoma

Common Name(s)

Glaucoma

Glaucoma is a group of diseases in which there is a blockage of fluid drainage from the eye. When fluid cannot drain properly from the eye, the pressure inside the eye may rise to a level that can damage the optic nerve that brings information from the back of the eye (retina) resulting in vision loss and blindness. This group of diseases makes up the second most common cause of blindness.

There are multiple types of glaucoma, the most common of which is open-angle glaucoma. In open-angle glaucoma, fluid builds up in the anterior chamber of the eye because it cannot drain through a meshwork structure between the colored part of the eye that controls light entry (iris) and the lens (cornea). In this form of glaucoma, side or peripheral vision is usually lost first. Other types of glaucoma include low-tension or normal-tension glaucoma, angle-closure glaucoma, congenital glaucoma, secondary glaucoma, neovascular glaucoma, pigmentary glaucoma, and pseudoexfoliation glaucoma. In angle-closure glaucoma, the iris blocks the channel that normally allows fluid leave the front of the eye. Symptoms of angle-closure glaucoma include eye pain, nausea, blurred vision, and redness of the eye. Medical attention should be sought promptly if angle-closure glaucoma is suspected.

Glaucoma can be diagnosed with a comprehensive dilated eye exam and by measuring intraocular pressure (IOP). Regular eye exams are important because some forms of glaucoma are often asymptomatic prior to permanent vision loss. Treatment options include medication, laser surgery to create holes in the meshwork and allow fluid to drain from the anterior chamber (laser trabeculoplasty), and surgery to alter the iris to allow fluid drainage. If you have been diagnosed with glaucoma, talk to your doctor about the most current treatment options. Support groups are good sources of more information and can connect you with other people living with glaucoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

Last Updated: 14 May 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

http://www.glaucoma.org

Last Updated: 14 May 2015

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

http://www.glaucomafoundation.org

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

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General Resources

Glaucoma Care and Treatment Information

Glaucoma Care and Treatment options

Updated 14 May 2015

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Free Glaucoma Newsletter

Information for glaucoma patients

Updated 14 May 2015

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Glaucoma Research Progress Reports

Information about glaucoma research progress

Updated 14 May 2015

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Low Vision Resources

Links to products and services available for people with low vision.

Updated 14 May 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glaucoma" returned 4318 free, full-text research articles on human participants. First 3 results:

Central corneal thickness in a Jordanian population and its association with different types of Glaucoma: cross-sectional study.
 

Author(s): Sana' Muhsen, Feras Alkhalaileh, Mohammad Hamdan, Saif Aldeen AlRyalat

Journal:

 

Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very variable between different ethnic groups. In this study, we aim to identify ...

Last Updated: 31 Dec 1969

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Association of Genes implicated in primary angle-closure Glaucoma and the ocular biometric parameters of anterior chamber depth and axial length in a northern Chinese population.
 

Author(s): Shaolin Wang, Wenjuan Zhuang, Jianqing Ma, Manyun Xu, Shunyu Piao, Juan Hao, Wen Zhang, Hao Chi, Zhongqi Xue, Shaoping Ha

Journal:

 

The membrane frizzled-related protein (MFRP) gene is involved in axial length (AL) regulation and MFRP mutations cause nanophthalmos; also, the hepatocyte growth factor (HGF) gene is reported to result in morphologic changes of the anterior segment and abnormal aqueous regulation ...

Last Updated: 31 Dec 1969

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Glaucoma severity and intraocular pressure reduction after cataract surgery in eyes with medically controlled glaucoma.
 

Author(s): Chungkwon Yoo, Behzad Amoozgar, Kyung-Sook Yang, Ji-Hye Park, Shan C Lin

Journal: Medicine (Baltimore). 2018 Oct;97(42):e12881.

 

To investigate the relationship between glaucoma severity and intraocular pressure (IOP) reduction after cataract surgery in patients with medically controlled primary open-angle glaucoma (POAG).Retrospective case series.This study included glaucoma suspects (GS) and POAG patients ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glaucoma" returned 486 free, full-text review articles on human participants. First 3 results:

Cytomegalovirus-related uncontrolled glaucoma in an immunocompetent patient: a case report and systematic review.
 

Author(s): Lei Xi, Liang Zhang, Wenlei Fei

Journal:

 

Cytomegalovirus can cause ocular anterior uveitis with ocular hypertension. Basis on the therapy, ocular pressure usually can be controlled. We report a case of a man who had unilateral cytomegalovirus anterior uveitis with refractory glaucoma during the process of treatment.

Last Updated: 31 Dec 1969

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Glaucoma Drugs in the Pipeline.
 

Author(s): Paul L Kaufman, Mary E Mohr, Scott P Riccomini, Carol A Rasmussen

Journal: Asia Pac J Ophthalmol (Phila). ;7(5):345-351.

 

Glaucoma is a chronic disease that can be challenging to treat for both patients and physicians. Most patients will require more than 1 medication over time to maintain their intraocular pressure (IOP) at a physiologically benign level. Patients may become refractory to existing compounds ...

Last Updated: 31 Dec 1969

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Comparison of pars plana with anterior chamber glaucoma drainage device implantation for glaucoma: a meta-analysis.
 

Author(s): Bin Wang, Wenwei Li

Journal:

 

The purpose of this study was to compare the efficacy and safety of pars plana glaucoma drainage device (PP GDD) with anterior chamber glaucoma drainage device (AC GDD) for the treatment of glaucoma.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

To Study the Function of the Retina in Glaucoma Patients Using PERG
 

Status: Recruiting

Condition Summary: Glaucoma

 

Last Updated: 30 Oct 2017

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Improve Glaucoma Medication Adherence
 

Status: Recruiting

Condition Summary: Glaucoma

 

Last Updated: 11 Oct 2018

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Artificial Intelligence-assisted Glaucoma Screening (AIAGS)
 

Status: Not yet recruiting

Condition Summary: Glaucoma Eye

 

Last Updated: 21 Sep 2018

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