Glaucoma

Common Name(s)

Glaucoma

Glaucoma is a group of diseases in which there is a blockage of fluid drainage from the eye. When fluid cannot drain properly from the eye, the pressure inside the eye may rise to a level that can damage the optic nerve that brings information from the back of the eye (retina) resulting in vision loss and blindness. This group of diseases makes up the second most common cause of blindness.

There are multiple types of glaucoma, the most common of which is open-angle glaucoma. In open-angle glaucoma, fluid builds up in the anterior chamber of the eye because it cannot drain through a meshwork structure between the colored part of the eye that controls light entry (iris) and the lens (cornea). In this form of glaucoma, side or peripheral vision is usually lost first. Other types of glaucoma include low-tension or normal-tension glaucoma, angle-closure glaucoma, congenital glaucoma, secondary glaucoma, neovascular glaucoma, pigmentary glaucoma, and pseudoexfoliation glaucoma. In angle-closure glaucoma, the iris blocks the channel that normally allows fluid leave the front of the eye. Symptoms of angle-closure glaucoma include eye pain, nausea, blurred vision, and redness of the eye. Medical attention should be sought promptly if angle-closure glaucoma is suspected.

Glaucoma can be diagnosed with a comprehensive dilated eye exam and by measuring intraocular pressure (IOP). Regular eye exams are important because some forms of glaucoma are often asymptomatic prior to permanent vision loss. Treatment options include medication, laser surgery to create holes in the meshwork and allow fluid to drain from the anterior chamber (laser trabeculoplasty), and surgery to alter the iris to allow fluid drainage. If you have been diagnosed with glaucoma, talk to your doctor about the most current treatment options. Support groups are good sources of more information and can connect you with other people living with glaucoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

Last Updated: 14 May 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glaucoma" for support, advocacy or research.

Glaucoma Research Foundation

We work to prevent vision loss from glaucoma by investing in innovative research, education, and support with the ultimate goal of finding a cure.

http://www.glaucoma.org

Last Updated: 14 May 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

http://www.glaucomafoundation.org

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

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General Resources

Glaucoma Care and Treatment Information

Glaucoma Care and Treatment options

Updated 14 May 2015

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Free Glaucoma Newsletter

Information for glaucoma patients

Updated 14 May 2015

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Glaucoma Research Progress Reports

Information about glaucoma research progress

Updated 14 May 2015

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Low Vision Resources

Links to products and services available for people with low vision.

Updated 14 May 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glaucoma" returned 3873 free, full-text research articles on human participants. First 3 results:

Structure-Function Relationships in Perimetric Glaucoma: Comparison of Minimum-Rim Width and Retinal Nerve Fiber Layer Parameters.
 

Author(s): Navid Amini, Ramin Daneshvar, Farideh Sharifipour, Pablo Romero, Sharon Henry, Joseph Caprioli, Kouros Nouri-Mahdavi

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 Sep;58(11):4623-4631.

 

To test the hypotheses that: (1) structure-function (SF) relationships between visual fields (VF) and Bruch's membrane opening-based minimum rim width (BMO-MRW) measurements are superior to those for peripapillary retinal nerve fiber layer (pRNFL) in perimetric glaucoma; (2) BMO-MRW ...

Last Updated: 12 Sep 2017

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Surgical treatment of neovascular glaucoma with Ex-PRESS glaucoma shunt: Case report.
 

Author(s): Teng-Chieh Yu, Gow-Lieng Tseng, Chun-Chen Chen, Shiow-Wen Liou

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7845.

 

Neovascular glaucoma (NVG) is one of the most aggressive types of glaucoma, and its abnormal fibrovascular tissue growth on the iris and trabecular meshwork may create difficulties to control the intraocular pressure (IOP) and perform the operation such as trabeculectomy.

Last Updated: 31 Aug 2017

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Magnetic Resonance Imaging of Optic Nerve Traction During Adduction in Primary Open-Angle Glaucoma With Normal Intraocular Pressure.
 

Author(s): Joseph L Demer, Robert A Clark, Soh Youn Suh, JoAnn A Giaconi, Kouros Nouri-Mahdavi, Simon K Law, Laura Bonelli, Anne L Coleman, Joseph Caprioli

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 Aug;58(10):4114-4125.

 

We used magnetic resonance imaging (MRI) to ascertain effects of optic nerve (ON) traction in adduction, a phenomenon proposed as neuropathic in primary open-angle glaucoma (POAG).

Last Updated: 22 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glaucoma" returned 408 free, full-text review articles on human participants. First 3 results:

Association of WDR36 polymorphisms with primary open angle glaucoma: A systematic review and meta-analysis.
 

Author(s): Ke Liu, Wenling He, Jun Zhao, Yingxia Zeng, Hongbo Cheng

Journal: Medicine (Baltimore). 2017 Jun;96(26):e7291.

 

The association of the WDR36 gene with glaucoma has been controversial in the literature. We therefore conducted a systematic review and meta-analysis to assess the association of all reported common polymorphisms in WDR36 with primary open angle glaucoma (POAG) and its subtypes: ...

Last Updated: 28 Jun 2017

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Biomarkers and Surrogate Endpoints: Lessons Learned From Glaucoma.
 

Author(s): Felipe A Medeiros

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 May;58(6):BIO20-BIO26.

 

With the recent progress in imaging technologies for assessment of structural damage in glaucoma, a debate has emerged on whether these measurements can be used as valid surrogate endpoints in clinical trials evaluating new therapies for the disease. A discussion of surrogates should ...

Last Updated: 5 May 2017

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Circulating biomarkers in glaucoma, age-related macular degeneration, and diabetic retinopathy.
 

Author(s): Madhu Nath, Nabanita Halder, Thirumurthy Velpandian

Journal: Indian J Ophthalmol. 2017 Mar;65(3):191-197.

 

Biomarkers to predict the altering physiological conditions over the period leading toward the ocular disorders are of major importance in therapeutics. Isolation and validation of the biomarkers specific to ocular diseases are a challenging task. Glaucoma is a neurodegenerative disease ...

Last Updated: 25 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Triamcinolone for Ahmed Glaucoma Valve
 

Status: Recruiting

Condition Summary: Glaucoma

 

Last Updated: 12 Jan 2016

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Improve Glaucoma Medication Adherence
 

Status: Not yet recruiting

Condition Summary: Glaucoma

 

Last Updated: 5 Jun 2017

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