Gestational Pemphigoid

Common Name(s)

Gestational Pemphigoid, Pemphigoid gestationis

Pemphigoid gestationis (PG), also known as gestational pemphigoid or herpes gestationis, is an autoimmune skin disorder associated with pregnancy. Signs and symptoms of the disorder typically present during the second or third trimester of pregnancy, but it may occur at any time during pregnancy or anywhere up to six weeks after giving birth. Although the signs and symptoms are variable, a red, itchy rash with blisters is common. The rash may occur in different parts of the body, but usually develops near the belly button and/or the arms and legs. The condition is caused by the production of antibodies that attack the person's body, leading to damage and consequently blister formation. Treatment generally involves systemic corticosteroids.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gestational Pemphigoid" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gestational Pemphigoid" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gestational Pemphigoid" returned 2 free, full-text research articles on human participants. First 3 results:

Gestational pemphigoid: placental morphology and function.
 

Author(s): Laura Huilaja, Kaarin Mäkikallio, Raija Sormunen, Jouko Lohi, Tiina Hurskainen, Kaisa Tasanen

Journal: Acta Derm. Venereol.. 2013 Jan;93(1):33-8.

 

Gestational pemphigoid (PG), a very rare pregnancy-associated bullous dermatosis, is associated with adverse pregnancy outcome (miscarriage, preterm delivery, foetal growth restriction). The major antigen in PG is collagen XVII (BP180). PG autoantibodies cross-react with collagen ...

Last Updated: 10 Jan 2013

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Detection of IgG autoantibodies in the sera of patients with bullous and gestational pemphigoid: ELISA studies utilizing a baculovirus-encoded form of bullous pemphigoid antigen 2.
 

Author(s): C Haase, L Büdinger, L Borradori, C Yee, H F Merk, K Yancey, M Hertl

Journal: J. Invest. Dermatol.. 1998 Mar;110(3):282-6.

 

Autoantibodies against the extracellular domain of bullous pemphigoid antigen 2 (BPAG2) are thought to play a key role in the pathogenesis of bullous pemphigoid and their detection may thus be of diagnostic and prognostic value. The aim of this study was to develop a standardized ...

Last Updated: 16 Apr 1998

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gestational Pemphigoid" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.