Gastroschisis

Common Name(s)

Gastroschisis

Gastroschisis is a congenital defect of the abdominal wall that occurs laterally to, and often to the right of, a normally closed umbilical ring. Visceral organs that herniate through the defect are not covered by a membrane. Gastroschisis is distinct from omphalocele ({164750}), which is characterized by herniation of abdominal contents through the base of the umbilical cord; in omphalocele, the visceral organs are covered by membranes (summary by {9:Mastroiacovo et al., 2007)}. Both omphalocele and gastroschisis, when they occur without other malformations, are probably multifactorial ({1:Baird and MacDonald, 1981}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroschisis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gastroschisis" returned 104 free, full-text research articles on human participants. First 3 results:

Transforming growth factor-beta 3 alters intestinal smooth muscle function: implications for gastroschisis-related intestinal dysfunction.
 

Author(s): S D Moore-Olufemi, A B Olsen, D M Hook-Dufresne, V Bandla, C S Cox

Journal: Dig. Dis. Sci.. 2015 May;60(5):1206-14.

 

Gastroschisis (GS) is a congenital abdominal wall defect that results in the development of GS-related intestinal dysfunction (GRID). Transforming growth factor-β, a pro-inflammatory cytokine, has been shown to cause organ dysfunction through alterations in vascular and airway smooth ...

Last Updated: 12 May 2015

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Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele.
 

Author(s): Kristin M Corey, Christoph P Hornik, Matthew M Laughon, Kerstin McHutchison, Reese H Clark, P Brian Smith

Journal: Early Hum. Dev.. 2014 Aug;90(8):421-4.

 

Gastroschisis and omphalocele are the most common anterior abdominal wall defects affecting infants. There are few large cohort studies describing the frequency of associated anomalies in infants with these 2 conditions. We describe associated anomalies and outcomes in infants with ...

Last Updated: 21 Jun 2014

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Is early delivery beneficial in gastroschisis?
 

Author(s): Helen Carnaghan, Susana Pereira, Catherine P James, Paul B Charlesworth, Marco Ghionzoli, Elkhouli Mohamed, Kate M K Cross, Edward Kiely, Shailesh Patel, Ashish Desai, Kypros Nicolaides, Joseph I Curry, Niyi Ade-Ajayi, Paolo De Coppi, Mark Davenport, Anna L David, Agostino Pierro, Simon Eaton

Journal: J. Pediatr. Surg.. 2014 Jun;49(6):928-33; discussion 933.

 

Gastroschisis neonates have delayed time to full enteral feeds (ENT), possibly due to bowel exposure to amniotic fluid. We investigated whether delivery at <37weeks improves neonatal outcomes of gastroschisis and impact of intra/extra-abdominal bowel dilatation (IABD/EABD).

Last Updated: 3 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gastroschisis" returned 6 free, full-text review articles on human participants. First 3 results:

Gastroschisis: antenatal sonographic predictors of adverse neonatal outcome.
 

Author(s): Rachael Page, Zachary Michael Ferraro, Felipe Moretti, Karen Fung Kee Fung

Journal: J Pregnancy. 2014 ;2014():239406.

 

The aim of this review was to identify clinically significant ultrasound predictors of adverse neonatal outcome in fetal gastroschisis.

Last Updated: 14 Jan 2015

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Left-sided gastroschisis with placenta findings: case report and literature review.
 

Author(s): Yang Shi, Christine K Farinelli, Michael S Chang, Philip M Carpenter

Journal: Int J Clin Exp Pathol. 2012 ;5(3):243-6.

 

Gastroschisis is a congenital abdominal-wall defect that typically occurs to the right of the umbilicus. Only twenty-one cases of left-sided gastroschisis have been described in the literature. Here we report a large left-sided gastroschisis with pulmonary hypoplasia, scoliosis, ventricular ...

Last Updated: 4 May 2012

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[Integrating the environmental clinic history into prenatal counseling and health care in gastroschisis: 2 case reports].
 

Author(s): J A Ortega García, M Martín, A Brea Lamas, C De Paco-Matallana, J I Ruiz Jiménez, O P Soldin

Journal: An Pediatr (Barc). 2010 Mar;72(3):215-9.

 

Gastroschisis is a malformation with an unknown aetiology, likely involving genetic and environmental risk factors (RF). The aim of this paper is to develop the paediatric environmental clinical history (PECH) of two patients with gastroschisis.

Last Updated: 15 Mar 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Silo Versus Primary Closure for Gastroschisis
 

Status: Recruiting

Condition Summary: Gastroschisis

 

Last Updated: 3 Feb 2015

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Music Therapy: An Adjunct To Gastroschisis Infants' Care
 

Status: Recruiting

Condition Summary: Gastroschisis

 

Last Updated: 31 Jul 2013

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Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care
 

Status: Recruiting

Condition Summary: Gastroschisis

 

Last Updated: 10 Dec 2013

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