Gastroparesis

Common Name(s)

Gastroparesis

Gastroparesis is a condition in which the stomach muscles do not function properly. When food moves into the stomach, muscles contract and relax to break down the food before it passes into the small intestine. If the stomach muscles do not work correctly, food does not move on to the small intestine, causing problems with digestion. Types of gastroparesis include idiopathic and diabetic. Sometimes gastroparesis may get better on its own but more often it is a lifelong condition (chronic).

Symptoms of gastroparesis include vomiting, nausea, feeling full after just a few bites, bloating, abdominal pain, lack of appetite, malnutrition, and changes in blood sugar levels. Complications include severe dehydration, malnutrition, and blood sugar fluctuations. The cause of gastroparesis is not clear, but seems to involve damage to the nerve that controls stomach muscles (the vagus nerve).

Risk factors include diabetes, abdominal or esophageal surgery, radiation therapy, infection, narcotic pain medications, and hypothyroidism (low thyroid function). Certain conditions such as Ehlers Danlos syndrome, postural orthostatic tachycardia syndrome, scleroderma, multiple sclerosis and Parkinson disease also increase a person’s risk. Idiopathic gastroparesis is more likely to affect young and middle aged women.

Diagnosis may include and upper GI scan, MRI, CT scan, special breath test, stomach emptying test and/or an endoscopy. There is no cure for gastroparesis and the treatments may not help everyone. Treatments may include diet changes, medication, and/or devices or procedures that help move the digested food through the stomach and controlling underlying causes. If you or a family member has been diagnosed with gastroparesis, talk to your doctor and specialists about the most current treatment options. Support groups are a good source for information and will help connect you with others living with gastroparesis.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

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Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

Last Updated: 17 Aug 2015

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G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

Last Updated: 28 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

View Details
Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

http://www.ehlers-danlos.org

Last Updated: 17 Aug 2015

View Details
G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

http://www.g-pact.org

Last Updated: 28 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gastroparesis" returned 127 free, full-text research articles on human participants. First 3 results:

Rectal sensitivity in diabetes patients with symptoms of gastroparesis.
 

Author(s): Eirik Søfteland, Christina Brock, Jens B Frøkjær, Magnus Simrén, Asbjørn M Drewes, Georg Dimcevski

Journal: J Diabetes Res. 2014 ;2014():784841.

 

In a clinical setting, diabetic autonomic complications (cardiac, gastrointestinal, urogenital, etc.) are often handled as separate entities. We investigated rectal sensitivity to heat, mechanical distension, and electrical stimulations in 20 patients with diabetes and symptoms of ...

Last Updated: 19 Aug 2014

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Combination of symptoms, syndrome and disease: treatment of refractory diabetic gastroparesis.
 

Author(s): Jun-Ling Li, Min Li, Bing Pang, Qiang Zhou, Jia-Xing Tian, Hong-Xing Liu, Xi-Yan Zhao, Xiao-Lin Tong

Journal: World J. Gastroenterol.. 2014 Jul;20(26):8674-80.

 

To assess effect of combination of symptoms, syndrome and disease on treatment of diabetic gastroparesis with severe nausea and vomiting.

Last Updated: 15 Jul 2014

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Rapid improvement in post-infectious gastroparesis symptoms with mirtazapine.
 

Author(s): Shinjini Kundu, Shari Rogal, Abdulkader Alam, David J Levinthal

Journal: World J. Gastroenterol.. 2014 Jun;20(21):6671-4.

 

We report the case of a 34-year-old woman with severe post-infectious gastroparesis who was transferred from an outside medical facility for a second opinion regarding management. This patient had no prior history of gastrointestinal symptoms. However, in the aftermath of a viral ...

Last Updated: 10 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gastroparesis" returned 20 free, full-text review articles on human participants. First 3 results:

Treatment of refractory diabetic gastroparesis: Western medicine and traditional Chinese medicine therapies.
 

Author(s): Bing Pang, Qiang Zhou, Jun-Ling Li, Lin-Hua Zhao, Xiao-Lin Tong

Journal: World J. Gastroenterol.. 2014 Jun;20(21):6504-14.

 

Refractory diabetic gastroparesis (DGP), a disorder that occurs in both type 1 and type 2 diabetics, is associated with severe symptoms, such as nausea and vomiting, and results in an economic burden on the health care system. In this article, the basic characteristics of refractory ...

Last Updated: 10 Jun 2014

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Xiangshaliujunzi Decoction for the treatment of diabetic gastroparesis: a systematic review.
 

Author(s): Jia-Xing Tian, Min Li, Jiang-Quan Liao, Wen-Ke Liu, Xiao-Lin Tong

Journal: World J. Gastroenterol.. 2014 Jan;20(2):561-8.

 

To assess the current clinical evidence of the effectiveness of Xiangshaliujunzi Decoction (XSLJZD) for the treatment of diabetic gastroparesis (DGP).

Last Updated: 27 Feb 2014

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Meta-analysis of acupuncture for relieving non-organic dyspeptic symptoms suggestive of diabetic gastroparesis.
 

Author(s): Mingxing Yang, Xiumin Li, Suhuan Liu, Zhipeng Li, Mei Xue, Dehong Gao, Xuejun Li, Shuyu Yang

Journal:

 

Acupuncture is widely used to treat diabetic patients with dyspeptic symptoms suggestive of gastroparesis in China. We conducted this systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of acupuncture for diabetic gastroparesis (DGP).

Last Updated: 17 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gastroparesis Registry 2
 

Status: Recruiting

Condition Summary: Gastroparesis; Diabetic Gastroparesis; Idiopathic Gastroparesis

 

Last Updated: 12 Mar 2015

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Acupuncture Treatment for Gastroparesis: a Pilot Study
 

Status: Recruiting

Condition Summary: Gastroparesis; Nausea; Vomiting; Abdominal Pain

 

Last Updated: 16 Jul 2012

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Treatment Use of Domperidone for Gastroparesis
 

Status: Available

Condition Summary: Gastroesophageal Reflux Disease; GERD; Gastroparesis

 

Last Updated: 15 Aug 2015

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