Gastroparesis

Common Name(s)

Gastroparesis

Gastroparesis is a condition in which the stomach muscles do not function properly. When food moves into the stomach, muscles contract and relax to break down the food before it passes into the small intestine. If the stomach muscles do not work correctly, food does not move on to the small intestine, causing problems with digestion. Types of gastroparesis include idiopathic and diabetic. Sometimes gastroparesis may get better on its own but more often it is a lifelong condition (chronic).

Symptoms of gastroparesis include vomiting, nausea, feeling full after just a few bites, bloating, abdominal pain, lack of appetite, malnutrition, and changes in blood sugar levels. Complications include severe dehydration, malnutrition, and blood sugar fluctuations. The cause of gastroparesis is not clear, but seems to involve damage to the nerve that controls stomach muscles (the vagus nerve).

Risk factors include diabetes, abdominal or esophageal surgery, radiation therapy, infection, narcotic pain medications, and hypothyroidism (low thyroid function). Certain conditions such as Ehlers Danlos syndrome, postural orthostatic tachycardia syndrome, scleroderma, multiple sclerosis and Parkinson disease also increase a person’s risk. Idiopathic gastroparesis is more likely to affect young and middle aged women.

Diagnosis may include and upper GI scan, MRI, CT scan, special breath test, stomach emptying test and/or an endoscopy. There is no cure for gastroparesis and the treatments may not help everyone. Treatments may include diet changes, medication, and/or devices or procedures that help move the digested food through the stomach and controlling underlying causes. If you or a family member has been diagnosed with gastroparesis, talk to your doctor and specialists about the most current treatment options. Support groups are a good source for information and will help connect you with others living with gastroparesis.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

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Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

Last Updated: 17 Aug 2015

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G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

Last Updated: 28 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

View Details
Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

http://www.ehlers-danlos.org

Last Updated: 17 Aug 2015

View Details
G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

http://www.g-pact.org

Last Updated: 28 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gastroparesis" returned 158 free, full-text research articles on human participants. First 3 results:

Gastric electrical stimulation for refractory gastroparesis: predictors of response and redefining a successful outcome.
 

Author(s): Bryan Richmond, Benny Chong, Asmita Modak, Mary Emmett, Kimball Knackstedt, Benjamin Dyer, Zachary AbuRahma

Journal: Am Surg. 2015 May;81(5):467-71.

 

Predictors of a favorable response and measures of success with gastric electrical stimulation (GES) for gastroparesis remain elusive. Published results remain inconsistent with respect to patient perceived benefit, despite statistical improvements in objective measures of symptom ...

Last Updated: 15 May 2015

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Prospective evaluation of gastric neurostimulation for diabetic gastroparesis in Canada.
 

Author(s): Himanish Panda, Philip Mitchell, Michael Curley, Michelle Buresi, Lynn Wilsack, Christopher N Andrews

Journal: Can J Gastroenterol Hepatol. 2015 May;29(4):198-202.

 

The efficacy of gastric neurostimulation therapy for diabetic gastroparesis (GP) in a 'real-life' Canadian setting has not been assessed.

Last Updated: 13 May 2015

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Duodenal rather than antral motility contractile parameters correlate with symptom severity in gastroparesis patients.
 

Author(s): K Barshop, K Staller, J Semler, B Kuo

Journal: Neurogastroenterol. Motil.. 2015 Mar;27(3):339-46.

 

Studies of symptomatic gastroparetics consistently find poor correlation with gastric emptying. We hypothesized that concomitant small bowel dysmotility may play a role in symptom causation in gastroparesis and sought to test this hypothesis by using wireless motility capsule (WMC) ...

Last Updated: 23 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gastroparesis" returned 29 free, full-text review articles on human participants. First 3 results:

Endoscopic treatment of gastroparesis.
 

Author(s): Thomas R McCarty, Tarun Rustagi

Journal: World J. Gastroenterol.. 2015 Jun;21(22):6842-9.

 

Gastroparesis has traditionally been a largely medically managed disease with refractory symptoms typically falling under the umbrella of the surgical domain. Surgical options include, but are not limited to, gastrostomy, jejunostomy, pyloromyotomy, or pyloroplasty, and the Food and ...

Last Updated: 16 Jun 2015

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Gastric arrhythmias in gastroparesis: low- and high-resolution mapping of gastric electrical activity.
 

Author(s): Gregory O'Grady, Thomas L Abell

Journal: Gastroenterol. Clin. North Am.. 2015 Mar;44(1):169-84.

 

Gastric arrhythmias occur in gastroparesis but their significance is debated. An improved understanding is currently emerging, including newly-defined histopathologic abnormalities in gastroparesis. In particular, the observation that interstitial cells of Cajal are depleted and injured ...

Last Updated: 10 Feb 2015

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Idiopathic gastroparesis.
 

Author(s): Henry P Parkman

Journal: Gastroenterol. Clin. North Am.. 2015 Mar;44(1):59-68.

 

Gastroparesis is a chronic symptomatic disorder of the stomach characterized by delayed emptying without evidence of mechanical obstruction. Idiopathic gastroparesis refers to gastroparesis of unknown cause not from diabetes; not from prior gastric surgery; not related to other endocrine, ...

Last Updated: 10 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gastroparesis Registry 2
 

Status: Recruiting

Condition Summary: Gastroparesis; Diabetic Gastroparesis; Idiopathic Gastroparesis

 

Last Updated: 18 Mar 2016

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G-POEM for Treatment of Refractory Gastroparesis
 

Status: Recruiting

Condition Summary: Diabetic Gastroparesis; Idiopathic Gastroparesis; Gastroparesis Postoperative

 

Last Updated: 5 May 2016

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Acupuncture Treatment for Gastroparesis: a Pilot Study
 

Status: Recruiting

Condition Summary: Gastroparesis; Nausea; Vomiting; Abdominal Pain

 

Last Updated: 16 Jul 2012

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