Gastroparesis

Common Name(s)

Gastroparesis

Gastroparesis is a condition in which the stomach doesn’t empty properly. In a normal, healthy individual, the stomach muscles push food and other materials down for digestion and excretion. In individuals suffering from gastroparesis, however, the muscles in the stomach responsible for those functions work poorly or in more extreme cases, do not work at all. This leads to common intestinal problems such as indigestion, nausea, diarrhea and vomiting. The severity of these symptoms varies widely by person and age and more specifically by the diet consumed by the person. Complications due to the gastroparesis can include low blood sugar levels and poor nutrition levels.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

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G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

Last Updated: 28 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroparesis" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

View Details
G-PACT

G-PACT is dedicated to increasing awareness of gastroparesis (GP), chronic intestinal pseudo obstruction (CIP), and colonic inertia (CI) among medical professionals, patients, and the general population. We are working towards finding a cure and/or better treatment options for people dealing with DTP. We provide educational resources, multiple support programs, patient advocacy programs, and other aid as needed to help patients cope and to provide hope to everyone afflicted with the condition.

http://www.g-pact.org

Last Updated: 28 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gastroparesis" returned 105 free, full-text research articles on human participants. First 3 results:

Gender aspects suggestive of gastroparesis in patients with diabetes mellitus: a cross-sectional survey.
 

Author(s): Ram Dickman, Julio Wainstein, Marek Glezerman, Yaron Niv, Mona Boaz

Journal:

 

It is suggested that symptoms related to gastroparesis are more common in female than in male patients with type 2 diabetes mellitus (T2DM). The association between sex and prevalence of symptoms suggestive of gastroparesis among patients with T2DM in Israel has not been reported. ...

Last Updated: 26 Feb 2014

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Clinical features and severity of gastric emptying delay in Brazilian patients with gastroparesis.
 

Author(s): Cláudio Marins Rocha Borges, Marie Secaf, Luiz Ernesto de Almeida Troncon

Journal: Arq Gastroenterol. ;50(4):270-6.

 

Gastroparesis is defined by delayed gastric emptying without mechanical obstruction of the gastroduodenal junction, which has been increasingly investigated. Nevertheless, knowledge on the relationships between etiology, symptoms and degree of delayed gastric emptying is limited.

Last Updated: 29 Jan 2014

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Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial.
 

Author(s): Henry P Parkman, Mark L Van Natta, Thomas L Abell, Richard W McCallum, Irene Sarosiek, Linda Nguyen, William J Snape, Kenneth L Koch, William L Hasler, Gianrico Farrugia, Linda Lee, Aynur Unalp-Arida, James Tonascia, Frank Hamilton, Pankaj J Pasricha

Journal: JAMA. 2013 Dec;310(24):2640-9.

 

Gastroparesis remains a challenging syndrome to manage, with few effective treatments and a lack of rigorously controlled trials. Tricyclic antidepressants are often used to treat refractory symptoms of nausea, vomiting, and abdominal pain. Evidence from well-designed studies for ...

Last Updated: 25 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gastroparesis" returned 16 free, full-text review articles on human participants. First 3 results:

Xiangshaliujunzi Decoction for the treatment of diabetic gastroparesis: a systematic review.
 

Author(s): Jia-Xing Tian, Min Li, Jiang-Quan Liao, Wen-Ke Liu, Xiao-Lin Tong

Journal: World J. Gastroenterol.. 2014 Jan;20(2):561-8.

 

To assess the current clinical evidence of the effectiveness of Xiangshaliujunzi Decoction (XSLJZD) for the treatment of diabetic gastroparesis (DGP).

Last Updated: 27 Feb 2014

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Meta-analysis of acupuncture for relieving non-organic dyspeptic symptoms suggestive of diabetic gastroparesis.
 

Author(s): Mingxing Yang, Xiumin Li, Suhuan Liu, Zhipeng Li, Mei Xue, Dehong Gao, Xuejun Li, Shuyu Yang

Journal:

 

Acupuncture is widely used to treat diabetic patients with dyspeptic symptoms suggestive of gastroparesis in China. We conducted this systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of acupuncture for diabetic gastroparesis (DGP).

Last Updated: 17 Jan 2014

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Diagnostic assessment of diabetic gastroparesis.
 

Author(s): Andrea S Shin, Michael Camilleri

Journal: Diabetes. 2013 Aug;62(8):2667-73.

 

Last Updated: 24 Jul 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gastroparesis Registry 2
 

Status: Recruiting

Condition Summary: Gastroparesis; Diabetic Gastroparesis; Idiopathic Gastroparesis

 

Last Updated: 16 Jun 2014

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Acupuncture Treatment for Gastroparesis: a Pilot Study
 

Status: Recruiting

Condition Summary: Gastroparesis; Nausea; Vomiting; Abdominal Pain

 

Last Updated: 16 Jul 2012

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Treatment Use of Domperidone for Gastroparesis
 

Status: Available

Condition Summary: Gastroesophageal Reflux Disease; GERD; Gastroparesis

 

Last Updated: 26 Aug 2014

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