Gastroesophageal Reflux

Common Name(s)

Gastroesophageal Reflux

Gastroesphageal Reflux is a condition in which the contents of the stomach, whether food, liquid, or acid, retract back to the esophagus irritating or burning the tract of the person. Gastroesophageal reflux is caused when the sphincter muscle, responsible for keeping the contents of the stomach in a proper digestion order, does not close well, allowing for contents to essentially leak back and potentially damage the esophagus. Alcohol, tobacco, and general obesity tend to propel the frequency in which this reflux occurs. Heartburn is a common associated syndrome with this condition and it is not out of the ordinary for a normal person to experience gastroesophageal reflux occasionally.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroesophageal Reflux" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Pediatric Adolescent Gastroesophageal Reflux Association

PAGER offers support and information to families affected by pediatric GERD and the professionals who treat them.

Last Updated: 21 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Gastroesophageal Reflux" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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Pediatric Adolescent Gastroesophageal Reflux Association

PAGER offers support and information to families affected by pediatric GERD and the professionals who treat them.

http://www.reflux.org

Last Updated: 21 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Gastroesophageal Reflux" returned 468 free, full-text research articles on human participants. First 3 results:

Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort.
 

Author(s): Carlos H Martinez, Yuka Okajima, Susan Murray, George R Washko, Fernando J Martinez, Edwin K Silverman, Jin Hwa Lee, Elizabeth A Regan, James D Crapo, Jeffrey L Curtis, Hiroto Hatabu, MeiLan K Han,

Journal:

 

The coexistence of gastroesophageal reflux disease (GERD) and COPD has been recognized, but there has been no comprehensive evaluation of the impact of GERD on COPD-related health status and patient-centered outcomes.

Last Updated: 11 Jun 2014

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Clinical and neurophysiologic characterization of an European family with hereditary sensory neuropathy, paroxysmal cough and gastroesophageal reflux.
 

Author(s): Pedro Barros, Hugo Morais, Catarina Santos, José Roriz, Paula Coutinho

Journal: Arq Neuropsiquiatr. 2014 Apr;72(4):269-72.

 

In 2002, Spring et al reported a family with an autosomal dominant form of hereditary sensory neuropathy; patients also presented adult onset of gastroesophageal reflux and cough. Since then, no further families have been described.

Last Updated: 24 Apr 2014

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Explaining the increased health care expenditures associated with gastroesophageal reflux disease among elderly Medicare beneficiaries with chronic obstructive pulmonary disease: a cost-decomposition analysis.
 

Author(s): Mayank Ajmera, Amit D Raval, Chan Shen, Usha Sambamoorthi

Journal:

 

To estimate excess health care expenditures associated with gastroesophageal reflux disease (GERD) among elderly individuals with chronic obstructive pulmonary disease (COPD) and examine the contribution of predisposing characteristics, enabling resources, need variables, personal ...

Last Updated: 21 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Gastroesophageal Reflux" returned 153 free, full-text review articles on human participants. First 3 results:

The effect of bariatric surgery on gastroesophageal reflux disease.
 

Author(s): Mustafa El-Hadi, Daniel W Birch, Richdeep S Gill, Shahzeer Karmali

Journal: Can J Surg. 2014 Apr;57(2):139-44.

 

Obesity is an epidemic that is known to play a role in the development of gastroesophageal reflux disease (GERD). Studies have shown that increasing body mass index plays a role in the incompetence of the gastroesophageal junction and that weight loss and lifestyle modifications reduce ...

Last Updated: 26 Mar 2014

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Efficacy of mosapride plus proton pump inhibitors for treatment of gastroesophageal reflux disease: a systematic review.
 

Author(s): Qing Liu, Chen-Chen Feng, Er-Man Wang, Xiu-Juan Yan, Sheng-Liang Chen

Journal: World J. Gastroenterol.. 2013 Dec;19(47):9111-8.

 

To assess the potential benefits of mosapride plus proton pump inhibitors (PPIs) in the treatment of gastroesophageal reflux disease.

Last Updated: 31 Dec 2013

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Are there risks associated with empiric acid suppression treatment of infants and children suspected of having gastroesophageal reflux disease?
 

Author(s): Erica Y Chung, Jeremy Yardley

Journal: Hosp Pediatr. 2013 Jan;3(1):16-23.

 

It has become common practice to empirically treat infants and children who have suspected gastroesophageal reflux disease by using acid-suppressive medications. However, evidence to support the effectiveness of these medications in the pediatric population is limited. With multiple ...

Last Updated: 10 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy
 

Status: Not yet recruiting

Condition Summary: Acid Reflux Esophagitis; Non-acid Reflux Esophagitis

 

Last Updated: 31 Jan 2014

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The Role of HIF-2a in the Pathogenesis of Reflux Esophagitis
 

Status: Recruiting

Condition Summary: Esophagitis; Reflux Esophagitis; Gastroesophageal Reflux Disease

 

Last Updated: 27 Feb 2013

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Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)
 

Status: Not yet recruiting

Condition Summary: Gastroesophageal Reflux Disease; Non Erosive Reflux Disease; Dyspepsia

 

Last Updated: 16 Jan 2014

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