Ganglioglioma

Common Name(s)

Ganglioglioma

A ganglioglioma is a rare type of brain tumor, accounting for approximately 1% of all brain tumors.   Gangliogliomas occur when a single cell in the brain starts to divide into more cells, forming a tumor.   This can occur when the cell randomly acquires changes (mutations) in genes that regulate how a cell divides.  Most gangliogliomas grow slowly and are considered benign.  However, up to 10% of gangliogliomas may grow more rapidly and become malignant, meaning the tumor affects the surrounding brain tissue.     The main treatment for ganglioglioma is removal of the entire tumor during surgery.  If the entire tumor is not removed, it has the potential to recur and may require additional surgery or treatments, such as radiation therapy or chemotherapy.  Unfortunately, because gangliogliomas are quite rare, there is limited information to show that radiation therapy or chemotherapy are effective treatments for this condition.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ganglioglioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ganglioglioma" returned 35 free, full-text research articles on human participants. First 3 results:

Ganglioglioma mimicking the cerebral abscess in advanced age: a case report.
 

Author(s): Cem Atabey, Ahmet Eroglu, Cem Dinc, Ahmet Colak

Journal: Turk Neurosurg. 2013 ;23(4):557-60.

 

Ganglioglioma is one of the rare mixed neuronal glial tumors of the central nerve system. It is responsible for 0.4 - 2% of the intracranial tumors observed in infants and young matures. Its most common localization is the supratentorial region. Typically, the first symptom is epilepsy. ...

Last Updated: 8 Oct 2013

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Brainstem ganglioglioma successfully treated with vemurafenib.
 

Author(s): Sarah Rush, Nicholas Foreman, Arthur Liu

Journal: J. Clin. Oncol.. 2013 Apr;31(10):e159-60.

 

Last Updated: 1 Apr 2013

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Last Updated: 31 Dec 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ganglioglioma" returned 7 free, full-text review articles on human participants. First 3 results:

Cerebellar ganglioglioma.
 

Author(s): Badr Fedoul, Zouhayr Souirti

Journal: Pan Afr Med J. 2012 ;12():12.

 

The cerebellar location of ganglioglioma (GG) is exceptional. We report one case of a 27-year-old man who underwent an intracranial hypertension syndrome and a static cerebellar syndrome. Brain magnetic resonance images revealed a cyst image in the vermis. Histological study after ...

Last Updated: 24 Jul 2012

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Infiltrative cerebellar ganglioglioma: conventional and advanced MRI, proton MR spectroscopic, and FDG PET findings in an 18-month-old child.
 

Author(s): U Löbel, D W Ellison, B L Shulkin, Z Patay

Journal: Clin Radiol. 2011 Feb;66(2):194-201.

 

Last Updated: 10 Jan 2011

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Anaplastic ganglioglioma in a middle-aged woman: a case report with a review of the literature.
 

Author(s): Dong Ho Kang, Chul Hee Lee, Soo Hyun Hwang, In Sung Park, Jong Woo Han, Jin Myung Jung

Journal: J. Korean Med. Sci.. 2007 Sep;22 Suppl():S139-44.

 

We report a case of anaplastic ganglioglioma. A 45-yr-old woman was admitted with a 5-month history of headache and dizziness, both of which progressed slowly. Preoperative magnetic resonance imaging revealed a strong enhancing mass in the left frontal lobe extending to the cingulate ...

Last Updated: 9 Oct 2007

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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
 

Status: Recruiting

Condition Summary: Brain Tumor; Low Grade Glioma; Astrocytoma; Ependymoma; Ganglioglioma

 

Last Updated: 10 Apr 2014

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Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors
 

Status: Recruiting

Condition Summary: Astrocytoma, Oligoastrocytoma, Mixed; Ganglioneuroma; Glioma; Ganglioglioma; Glioblastoma Multiforme Glioma

 

Last Updated: 15 May 2014

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